Why the Soil Matters: Uterine Aging in IVF with KevinMD (Episode 88)

In this thought-provoking episode of Fertile Talks, Dr. Yemi Famuyiwa joins KevinMD to explore a topic that is often overlooked in fertility care: uterine aging. While much of the conversation around fertility focuses on egg quality, emerging research shows that the uterus—the “soil”—ages as well, and may significantly influence implantation and pregnancy success, even when using young donor eggs.

Dr. Famuyiwa breaks down the science behind endometrial receptivity, epigenetic drift, and the buildup of senescent “zombie” cells that create an inflammatory environment within the uterus. She explains why a normal progesterone level doesn’t always mean the uterus can respond properly, and how age-related changes in the uterine lining may impact IVF outcomes.

This episode sheds light on the evolving science of reproductive aging and reminds patients and providers alike: fertility is not just about the seed. The soil matters too.

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Connect with Dr. Famuyiwa

Dr. Famuyiwa's practice: https://montgomeryfertilitycenter.com/

Social media links and other resources: https://linktr.ee/Dr.Yemi_Famuyiwa

About Dr. Famuyiwa: https://montgomeryfertilitycenter.com/dr-yemi-adesanya-famuyiwa/

Disclaimer: The information provided in this podcast is for educational purposes only and should not be considered medical advice. Please consult with a qualified healthcare professional before making any decisions regarding your health.