{"version":"1.0.0","segments":[{"speaker":"John Simboli","startTime":0.0,"endTime":1.92,"body":"Welcome to"},{"speaker":"John Simboli","startTime":0.0,"endTime":1.92,"body":"BioBoss. Stacy."},{"speaker":"Stacy Lindborg","startTime":2.46,"endTime":4.44,"body":"Thank you. It's"},{"speaker":"Stacy Lindborg","startTime":2.46,"endTime":4.44,"body":"a delight to be here."},{"speaker":"John Simboli","startTime":4.44,"endTime":7.8,"body":"What led you to"},{"speaker":"John Simboli","startTime":4.44,"endTime":7.8,"body":"your role as CEO at Immunon?"},{"speaker":"Stacy Lindborg","startTime":8.22,"endTime":10.86,"body":"I really step"},{"speaker":"Stacy Lindborg","startTime":8.22,"endTime":10.86,"body":"back and I think about where the"},{"speaker":"Stacy Lindborg","startTime":10.86,"endTime":15.0,"body":"journey began. It really started"},{"speaker":"Stacy Lindborg","startTime":10.86,"endTime":15.0,"body":"with a phenomenal company, so"},{"speaker":"Stacy Lindborg","startTime":15.06,"endTime":20.16,"body":"Eli Lilly and Company. I was"},{"speaker":"Stacy Lindborg","startTime":15.06,"endTime":20.16,"body":"there for almost half my career."},{"speaker":"Stacy Lindborg","startTime":20.22,"endTime":24.48,"body":"And I think that where you start"},{"speaker":"Stacy Lindborg","startTime":20.22,"endTime":24.48,"body":"and who you're exposed to,"},{"speaker":"Stacy Lindborg","startTime":25.08,"endTime":28.725,"body":"really can set you off on a"},{"speaker":"Stacy Lindborg","startTime":25.08,"endTime":28.725,"body":"different course. And I was"},{"speaker":"Stacy Lindborg","startTime":28.725,"endTime":34.065,"body":"given the opportunity very early"},{"speaker":"Stacy Lindborg","startTime":28.725,"endTime":34.065,"body":"in my career, and I think as you"},{"speaker":"Stacy Lindborg","startTime":34.065,"endTime":38.085,"body":"leave great companies, you also"},{"speaker":"Stacy Lindborg","startTime":34.065,"endTime":38.085,"body":"see how different they are. So"},{"speaker":"Stacy Lindborg","startTime":38.085,"endTime":43.245,"body":"Lilly is, I think, phenomenal in"},{"speaker":"Stacy Lindborg","startTime":38.085,"endTime":43.245,"body":"thinking about people and"},{"speaker":"Stacy Lindborg","startTime":43.245,"endTime":48.09,"body":"development and really setting"},{"speaker":"Stacy Lindborg","startTime":43.245,"endTime":48.09,"body":"perhaps expectations long beyond"},{"speaker":"Stacy Lindborg","startTime":48.09,"endTime":52.35,"body":"you can expect, especially"},{"speaker":"Stacy Lindborg","startTime":48.09,"endTime":52.35,"body":"earlier in your career. And they"},{"speaker":"Stacy Lindborg","startTime":52.35,"endTime":56.85,"body":"gave me just a series of"},{"speaker":"Stacy Lindborg","startTime":52.35,"endTime":56.85,"body":"opportunities that taught me"},{"speaker":"Stacy Lindborg","startTime":56.85,"endTime":60.57,"body":"that I had formal training, I"},{"speaker":"Stacy Lindborg","startTime":56.85,"endTime":60.57,"body":"had industry knowledge that I"},{"speaker":"Stacy Lindborg","startTime":60.57,"endTime":64.89,"body":"was accumulating, and I had the"},{"speaker":"Stacy Lindborg","startTime":60.57,"endTime":64.89,"body":"ability to really think at a"},{"speaker":"Stacy Lindborg","startTime":64.89,"endTime":68.67,"body":"macro level, as well as really"},{"speaker":"Stacy Lindborg","startTime":64.89,"endTime":68.67,"body":"getting to know drug"},{"speaker":"Stacy Lindborg","startTime":68.67,"endTime":72.375,"body":"development. And I really think"},{"speaker":"Stacy Lindborg","startTime":68.67,"endTime":72.375,"body":"that's what started it. I was"},{"speaker":"Stacy Lindborg","startTime":72.435,"endTime":76.275,"body":"very early, given an opportunity"},{"speaker":"Stacy Lindborg","startTime":72.435,"endTime":76.275,"body":"to step into more of a"},{"speaker":"Stacy Lindborg","startTime":76.275,"endTime":79.935,"body":"leadership capacity for a"},{"speaker":"Stacy Lindborg","startTime":76.275,"endTime":79.935,"body":"blockbuster that was a product"},{"speaker":"Stacy Lindborg","startTime":79.935,"endTime":84.135,"body":"that took the lead revenue"},{"speaker":"Stacy Lindborg","startTime":79.935,"endTime":84.135,"body":"driving for Lilly after Prozac"},{"speaker":"Stacy Lindborg","startTime":84.135,"endTime":88.455,"body":"went off patent and was asked to"},{"speaker":"Stacy Lindborg","startTime":84.135,"endTime":88.455,"body":"take over the schizophrenia"},{"speaker":"Stacy Lindborg","startTime":88.455,"endTime":93.015,"body":"brand for Zyprexa. This is, you"},{"speaker":"Stacy Lindborg","startTime":88.455,"endTime":93.015,"body":"know, a product that reached, I"},{"speaker":"Stacy Lindborg","startTime":93.015,"endTime":98.04,"body":"think, $ 4.7 billion in peak"},{"speaker":"Stacy Lindborg","startTime":93.015,"endTime":98.04,"body":"sales, and we were languishing"},{"speaker":"Stacy Lindborg","startTime":98.04,"endTime":103.56,"body":"in schizophrenia sales. So as a"},{"speaker":"Stacy Lindborg","startTime":98.04,"endTime":103.56,"body":"young PhD, I found myself with"},{"speaker":"Stacy Lindborg","startTime":103.56,"endTime":108.36,"body":"marketing staff, really talented"},{"speaker":"Stacy Lindborg","startTime":103.56,"endTime":108.36,"body":"commercial guys reporting to me,"},{"speaker":"Stacy Lindborg","startTime":108.84,"endTime":113.52,"body":"the manufacturing capacity, and"},{"speaker":"Stacy Lindborg","startTime":108.84,"endTime":113.52,"body":"then R\u0026D and developing new"},{"speaker":"Stacy Lindborg","startTime":113.52,"endTime":117.645,"body":"indications. And I think it"},{"speaker":"Stacy Lindborg","startTime":113.52,"endTime":117.645,"body":"really taught me how much I"},{"speaker":"Stacy Lindborg","startTime":117.645,"endTime":122.325,"body":"loved that intersection between"},{"speaker":"Stacy Lindborg","startTime":117.645,"endTime":122.325,"body":"business and science. And then"},{"speaker":"Stacy Lindborg","startTime":122.385,"endTime":127.005,"body":"another pivotal role was really"},{"speaker":"Stacy Lindborg","startTime":122.385,"endTime":127.005,"body":"getting to look at the portfolio"},{"speaker":"Stacy Lindborg","startTime":127.065,"endTime":130.365,"body":"and be accountable for R\u0026D"},{"speaker":"Stacy Lindborg","startTime":127.065,"endTime":130.365,"body":"strategy and actually sit with"},{"speaker":"Stacy Lindborg","startTime":130.845,"endTime":135.105,"body":"John Lechleiter, at the time the"},{"speaker":"Stacy Lindborg","startTime":130.845,"endTime":135.105,"body":"CEO, and I sat at their"},{"speaker":"Stacy Lindborg","startTime":135.405,"endTime":139.185,"body":"executive leadership in a"},{"speaker":"Stacy Lindborg","startTime":135.405,"endTime":139.185,"body":"week-long, long range plan where"},{"speaker":"Stacy Lindborg","startTime":139.23,"endTime":143.31,"body":"we were plotting the year's,"},{"speaker":"Stacy Lindborg","startTime":139.23,"endTime":143.31,"body":"what we called y-z, which was"},{"speaker":"Stacy Lindborg","startTime":143.31,"endTime":145.95,"body":"when we would lose a lot of"},{"speaker":"Stacy Lindborg","startTime":143.31,"endTime":145.95,"body":"patents of drugs that had y's"},{"speaker":"Stacy Lindborg","startTime":145.95,"endTime":149.55,"body":"and z's in their names. And, you"},{"speaker":"Stacy Lindborg","startTime":145.95,"endTime":149.55,"body":"know, actually talking about how"},{"speaker":"Stacy Lindborg","startTime":149.55,"endTime":153.03,"body":"we would reinvigorate the"},{"speaker":"Stacy Lindborg","startTime":149.55,"endTime":153.03,"body":"company and the investments, and"},{"speaker":"Stacy Lindborg","startTime":153.03,"endTime":157.83,"body":"how we would survive that. And"},{"speaker":"Stacy Lindborg","startTime":153.03,"endTime":157.83,"body":"those are really formative"},{"speaker":"Stacy Lindborg","startTime":157.89,"endTime":163.095,"body":"experiences early in my career"},{"speaker":"Stacy Lindborg","startTime":157.89,"endTime":163.095,"body":"that caused me to be open, then"},{"speaker":"Stacy Lindborg","startTime":163.095,"endTime":164.835,"body":"to future opportunities."},{"speaker":"John Simboli","startTime":165.015,"endTime":167.835,"body":"At what point did"},{"speaker":"John Simboli","startTime":165.015,"endTime":167.835,"body":"you think to yourself, I'm ready"},{"speaker":"John Simboli","startTime":167.835,"endTime":171.435,"body":"to take that step. I'm ready to"},{"speaker":"John Simboli","startTime":167.835,"endTime":171.435,"body":"become the leader of the"},{"speaker":"John Simboli","startTime":171.615,"endTime":172.635,"body":"biopharma company."},{"speaker":"Unknown","startTime":173.295,"endTime":176.295,"body":"I looked at every job"},{"speaker":"Unknown","startTime":173.295,"endTime":176.295,"body":"that I was offered at Lilly,"},{"speaker":"Unknown","startTime":176.295,"endTime":179.955,"body":"which, you know, again, a real"},{"speaker":"Unknown","startTime":176.295,"endTime":179.955,"body":"strength for them was that they,"},{"speaker":"Unknown","startTime":180.015,"endTime":184.275,"body":"unsolicited, would come and give"},{"speaker":"Unknown","startTime":180.015,"endTime":184.275,"body":"new opportunities. I never found"},{"speaker":"Unknown","startTime":184.275,"endTime":187.98,"body":"that I had to go advocate and"},{"speaker":"Unknown","startTime":184.275,"endTime":187.98,"body":"ask for ways that I could grow"},{"speaker":"Unknown","startTime":187.98,"endTime":192.24,"body":"and contribute. And so I really"},{"speaker":"Unknown","startTime":187.98,"endTime":192.24,"body":"kind of looked at every"},{"speaker":"Unknown","startTime":192.24,"endTime":196.14,"body":"opportunity, again, first half"},{"speaker":"Unknown","startTime":192.24,"endTime":196.14,"body":"of my career. Can I learn? Can I"},{"speaker":"Unknown","startTime":196.14,"endTime":202.02,"body":"contribute? And, you know, and"},{"speaker":"Unknown","startTime":196.14,"endTime":202.02,"body":"will I grow? I think that really"},{"speaker":"Unknown","startTime":202.02,"endTime":205.98,"body":"just continued to open, you"},{"speaker":"Unknown","startTime":202.02,"endTime":205.98,"body":"know, different doors. And I"},{"speaker":"Unknown","startTime":205.98,"endTime":209.625,"body":"went from Lilly to Biogen. So"},{"speaker":"Unknown","startTime":205.98,"endTime":209.625,"body":"every company got smaller and"},{"speaker":"Unknown","startTime":209.625,"endTime":213.585,"body":"smaller. You know, it's"},{"speaker":"Unknown","startTime":209.625,"endTime":213.585,"body":"interesting. My time at Biogen"},{"speaker":"Unknown","startTime":213.645,"endTime":217.665,"body":"offered, you know, insights into"},{"speaker":"Unknown","startTime":213.645,"endTime":217.665,"body":"broader, bigger teams, lots of"},{"speaker":"Unknown","startTime":217.665,"endTime":222.585,"body":"functions. When I joined my"},{"speaker":"Unknown","startTime":217.665,"endTime":222.585,"body":"previous company, Brainstorm"},{"speaker":"Unknown","startTime":222.585,"endTime":226.125,"body":"Cell Therapeutics, you know, I"},{"speaker":"Unknown","startTime":222.585,"endTime":226.125,"body":"was getting exposed to different"},{"speaker":"Unknown","startTime":226.125,"endTime":229.065,"body":"modalities. We had an autologous"},{"speaker":"Unknown","startTime":226.125,"endTime":229.065,"body":"cell therapy. This was a"},{"speaker":"Unknown","startTime":229.065,"endTime":233.67,"body":"micro-cap company. It was a very"},{"speaker":"Unknown","startTime":229.065,"endTime":233.67,"body":"different understanding of, you"},{"speaker":"Unknown","startTime":233.67,"endTime":237.75,"body":"know, really our existence and"},{"speaker":"Unknown","startTime":233.67,"endTime":237.75,"body":"how we continue to advance an"},{"speaker":"Unknown","startTime":237.75,"endTime":242.31,"body":"amazing product. I went there as"},{"speaker":"Unknown","startTime":237.75,"endTime":242.31,"body":"head of global clinical"},{"speaker":"Unknown","startTime":242.31,"endTime":246.45,"body":"development, and then was asked"},{"speaker":"Unknown","startTime":242.31,"endTime":246.45,"body":"to step in as Co-CEO in advance"},{"speaker":"Unknown","startTime":246.87,"endTime":251.85,"body":"to that. And I think it really"},{"speaker":"Unknown","startTime":246.87,"endTime":251.85,"body":"gave me familiarity with the"},{"speaker":"Unknown","startTime":251.85,"endTime":255.615,"body":"breadth of stakeholders that one"},{"speaker":"Unknown","startTime":251.85,"endTime":255.615,"body":"needs to balance and communicate"},{"speaker":"Unknown","startTime":255.615,"endTime":259.395,"body":"with and as you're thinking"},{"speaker":"Unknown","startTime":255.615,"endTime":259.395,"body":"about as a CEO. And it really"},{"speaker":"Unknown","startTime":259.395,"endTime":264.255,"body":"then prepared me when I was"},{"speaker":"Unknown","startTime":259.395,"endTime":264.255,"body":"asked to consider my current"},{"speaker":"Unknown","startTime":264.255,"endTime":268.215,"body":"role. So it was ireally a"},{"speaker":"Unknown","startTime":264.255,"endTime":268.215,"body":"natural evolution, and it felt"},{"speaker":"Unknown","startTime":268.515,"endTime":272.655,"body":"like any big problem. If you can"},{"speaker":"Unknown","startTime":268.515,"endTime":272.655,"body":"break it down into what's"},{"speaker":"Unknown","startTime":272.655,"endTime":276.255,"body":"needed, what do I bring as a"},{"speaker":"Unknown","startTime":272.655,"endTime":276.255,"body":"strength? What am I going to not"},{"speaker":"Unknown","startTime":276.3,"endTime":279.48,"body":"know, always have things we"},{"speaker":"Unknown","startTime":276.3,"endTime":279.48,"body":"don't know, and how am I going"},{"speaker":"Unknown","startTime":279.48,"endTime":284.04,"body":"to seek advice and get input."},{"speaker":"Unknown","startTime":279.48,"endTime":284.04,"body":"And it then feels like it's a,"},{"speaker":"Unknown","startTime":284.04,"endTime":288.18,"body":"you know, a doable assignment,"},{"speaker":"Unknown","startTime":284.04,"endTime":288.18,"body":"which we all want to succeed and"},{"speaker":"Unknown","startTime":288.18,"endTime":291.42,"body":"add value. And I definitely felt"},{"speaker":"Unknown","startTime":288.18,"endTime":291.42,"body":"prepared, prepared for it,"},{"speaker":"John Simboli","startTime":292.08,"endTime":295.44,"body":"As you assumed the"},{"speaker":"John Simboli","startTime":292.08,"endTime":295.44,"body":"leadership role in your previous"},{"speaker":"John Simboli","startTime":295.44,"endTime":298.38,"body":"company and then in your current"},{"speaker":"John Simboli","startTime":295.44,"endTime":298.38,"body":"one, what kinds of things"},{"speaker":"John Simboli","startTime":298.44,"endTime":302.745,"body":"matched how you thought it might"},{"speaker":"John Simboli","startTime":298.44,"endTime":302.745,"body":"be to be the CEO, what things"},{"speaker":"John Simboli","startTime":302.745,"endTime":303.345,"body":"were different?"},{"speaker":"Stacy Lindborg","startTime":303.885,"endTime":307.245,"body":"In my last role,"},{"speaker":"Stacy Lindborg","startTime":303.885,"endTime":307.245,"body":"I was sharing a job, I was"},{"speaker":"Stacy Lindborg","startTime":307.245,"endTime":311.865,"body":"working with a phenomenal"},{"speaker":"Stacy Lindborg","startTime":307.245,"endTime":311.865,"body":"partner, with a very established"},{"speaker":"Stacy Lindborg","startTime":311.865,"endTime":316.485,"body":"business sphere, or expertise, a"},{"speaker":"Stacy Lindborg","startTime":311.865,"endTime":316.485,"body":"broad network, a lot of things"},{"speaker":"Stacy Lindborg","startTime":316.485,"endTime":320.925,"body":"that really made us very"},{"speaker":"Stacy Lindborg","startTime":316.485,"endTime":320.925,"body":"complementary. And I think even"},{"speaker":"Stacy Lindborg","startTime":320.985,"endTime":326.49,"body":"now at Immunon, I have a partner"},{"speaker":"Stacy Lindborg","startTime":320.985,"endTime":326.49,"body":"an executive director who was"},{"speaker":"Stacy Lindborg","startTime":326.49,"endTime":330.75,"body":"CEO for 13 years, and had a very"},{"speaker":"Stacy Lindborg","startTime":326.49,"endTime":330.75,"body":"different and complementary set"},{"speaker":"Stacy Lindborg","startTime":330.75,"endTime":334.95,"body":"of experiences, a very trusted"},{"speaker":"Stacy Lindborg","startTime":330.75,"endTime":334.95,"body":"relationship, both of them have"},{"speaker":"Stacy Lindborg","startTime":334.95,"endTime":339.87,"body":"been. So I think I came in and I"},{"speaker":"Stacy Lindborg","startTime":334.95,"endTime":339.87,"body":"mean, I even think about my own"},{"speaker":"Stacy Lindborg","startTime":339.87,"endTime":345.21,"body":"leadership style, what resonates"},{"speaker":"Stacy Lindborg","startTime":339.87,"endTime":345.21,"body":"really deeply with me, and it's"},{"speaker":"Stacy Lindborg","startTime":345.21,"endTime":348.255,"body":"been a central part of how I've"},{"speaker":"Stacy Lindborg","startTime":345.21,"endTime":348.255,"body":"led across my entire career, is"},{"speaker":"Stacy Lindborg","startTime":348.315,"endTime":351.435,"body":"more servant leadership. And I"},{"speaker":"Stacy Lindborg","startTime":348.315,"endTime":351.435,"body":"think you know that really is"},{"speaker":"Stacy Lindborg","startTime":351.435,"endTime":354.615,"body":"ultimately grounded in humility."},{"speaker":"Stacy Lindborg","startTime":351.435,"endTime":354.615,"body":"And I think that when we put"},{"speaker":"Stacy Lindborg","startTime":354.615,"endTime":358.095,"body":"ourselves in too big of a place,"},{"speaker":"Stacy Lindborg","startTime":354.615,"endTime":358.095,"body":"and we're fearful then of"},{"speaker":"Stacy Lindborg","startTime":358.875,"endTime":362.055,"body":"finding out something we don't"},{"speaker":"Stacy Lindborg","startTime":358.875,"endTime":362.055,"body":"know, versus just appreciating"},{"speaker":"Stacy Lindborg","startTime":362.055,"endTime":367.035,"body":"that we all are going to bring"},{"speaker":"Stacy Lindborg","startTime":362.055,"endTime":367.035,"body":"things that you know will shine"},{"speaker":"Stacy Lindborg","startTime":367.035,"endTime":370.26,"body":"compared to other people. But"},{"speaker":"Stacy Lindborg","startTime":367.035,"endTime":370.26,"body":"then we all have to learn it"},{"speaker":"Stacy Lindborg","startTime":370.26,"endTime":375.42,"body":"takes away a pressure of not"},{"speaker":"Stacy Lindborg","startTime":370.26,"endTime":375.42,"body":"showing up, you know, and I"},{"speaker":"Stacy Lindborg","startTime":375.42,"endTime":378.0,"body":"don't. I don't know that anybody"},{"speaker":"Stacy Lindborg","startTime":375.42,"endTime":378.0,"body":"intentionally does that, but"},{"speaker":"Stacy Lindborg","startTime":378.0,"endTime":380.04,"body":"feeling this pressure that you"},{"speaker":"Stacy Lindborg","startTime":378.0,"endTime":380.04,"body":"have to know everything"},{"speaker":"Stacy Lindborg","startTime":380.04,"endTime":384.06,"body":"certainly I don't. I don't shy"},{"speaker":"Stacy Lindborg","startTime":380.04,"endTime":384.06,"body":"away from a viewpoint on"},{"speaker":"Stacy Lindborg","startTime":384.06,"endTime":388.38,"body":"strategy and execution, but I"},{"speaker":"Stacy Lindborg","startTime":384.06,"endTime":388.38,"body":"think that style is you"},{"speaker":"Stacy Lindborg","startTime":388.38,"endTime":391.965,"body":"ultimately think about an"},{"speaker":"Stacy Lindborg","startTime":388.38,"endTime":391.965,"body":"organization. You have a head of"},{"speaker":"Stacy Lindborg","startTime":391.965,"endTime":394.965,"body":"an organization. I have"},{"speaker":"Stacy Lindborg","startTime":391.965,"endTime":394.965,"body":"accountabilities in my job, but"},{"speaker":"Stacy Lindborg","startTime":395.025,"endTime":397.845,"body":"really the most critical thing"},{"speaker":"Stacy Lindborg","startTime":395.025,"endTime":397.845,"body":"that I have to be thinking about"},{"speaker":"Stacy Lindborg","startTime":397.845,"endTime":403.725,"body":"is my team, and how is my team"},{"speaker":"Stacy Lindborg","startTime":397.845,"endTime":403.725,"body":"going to accomplish what is a"},{"speaker":"Stacy Lindborg","startTime":403.725,"endTime":407.385,"body":"very difficult task of bringing"},{"speaker":"Stacy Lindborg","startTime":403.725,"endTime":407.385,"body":"forward a novel therapeutic"},{"speaker":"Stacy Lindborg","startTime":407.445,"endTime":411.765,"body":"extending the life of people"},{"speaker":"Stacy Lindborg","startTime":407.445,"endTime":411.765,"body":"that have cancer, which is what"},{"speaker":"Stacy Lindborg","startTime":411.765,"endTime":415.365,"body":"we're focused on right now, and"},{"speaker":"Stacy Lindborg","startTime":411.765,"endTime":415.365,"body":"find ways that you're empowering"},{"speaker":"Stacy Lindborg","startTime":415.365,"endTime":418.29,"body":"them, you're removing obstacles,"},{"speaker":"Stacy Lindborg","startTime":415.365,"endTime":418.29,"body":"you know, you're really"},{"speaker":"Stacy Lindborg","startTime":418.29,"endTime":421.83,"body":"fostering an environment where"},{"speaker":"Stacy Lindborg","startTime":418.29,"endTime":421.83,"body":"people can thrive, and"},{"speaker":"Stacy Lindborg","startTime":421.89,"endTime":425.37,"body":"ultimately recognizing that for"},{"speaker":"Stacy Lindborg","startTime":421.89,"endTime":425.37,"body":"myself, but also for my team, no"},{"speaker":"Stacy Lindborg","startTime":425.37,"endTime":429.51,"body":"one has all the answers. Our"},{"speaker":"Stacy Lindborg","startTime":425.37,"endTime":429.51,"body":"business, the world that"},{"speaker":"Stacy Lindborg","startTime":429.51,"endTime":433.35,"body":"biopharma lives to change, at"},{"speaker":"Stacy Lindborg","startTime":429.51,"endTime":433.35,"body":"the end of the day, and even as"},{"speaker":"Stacy Lindborg","startTime":433.35,"endTime":437.13,"body":"you get to the commercial realm,"},{"speaker":"Stacy Lindborg","startTime":433.35,"endTime":437.13,"body":"no one has all the answers. We"},{"speaker":"Stacy Lindborg","startTime":437.13,"endTime":442.095,"body":"all come with a great plan, and"},{"speaker":"Stacy Lindborg","startTime":437.13,"endTime":442.095,"body":"I think that our ability to"},{"speaker":"Stacy Lindborg","startTime":442.095,"endTime":446.955,"body":"learn and evolve and be nimble,"},{"speaker":"Stacy Lindborg","startTime":442.095,"endTime":446.955,"body":"ultimately, and I view humility"},{"speaker":"Stacy Lindborg","startTime":446.955,"endTime":450.495,"body":"as a huge part of that. Because,"},{"speaker":"Stacy Lindborg","startTime":446.955,"endTime":450.495,"body":"you know, if we think we, if we"},{"speaker":"Stacy Lindborg","startTime":450.495,"endTime":454.875,"body":"think we know everything going"},{"speaker":"Stacy Lindborg","startTime":450.495,"endTime":454.875,"body":"into it, I think you know our"},{"speaker":"Stacy Lindborg","startTime":454.875,"endTime":458.535,"body":"business will teach us"},{"speaker":"Stacy Lindborg","startTime":454.875,"endTime":458.535,"body":"otherwise. But it keeps us"},{"speaker":"Stacy Lindborg","startTime":458.595,"endTime":462.42,"body":"focused on, what did we learn,"},{"speaker":"Stacy Lindborg","startTime":458.595,"endTime":462.42,"body":"and how do we improve the next"},{"speaker":"Stacy Lindborg","startTime":462.42,"endTime":465.48,"body":"cycle, and what do we anticipate"},{"speaker":"Stacy Lindborg","startTime":462.42,"endTime":465.48,"body":"differently? How do we adapt,"},{"speaker":"Stacy Lindborg","startTime":465.78,"endTime":468.36,"body":"and how do we accomplish it"},{"speaker":"Stacy Lindborg","startTime":465.78,"endTime":468.36,"body":"together? I think that's really"},{"speaker":"Stacy Lindborg","startTime":468.36,"endTime":468.9,"body":"critical."},{"speaker":"John Simboli","startTime":469.5,"endTime":472.8,"body":"I want to go next"},{"speaker":"John Simboli","startTime":469.5,"endTime":472.8,"body":"with a question about your"},{"speaker":"John Simboli","startTime":472.8,"endTime":477.72,"body":"statistics background. That"},{"speaker":"John Simboli","startTime":472.8,"endTime":477.72,"body":"sounds like an unusual"},{"speaker":"John Simboli","startTime":477.78,"endTime":480.54,"body":"contribution you can make. There"},{"speaker":"John Simboli","startTime":477.78,"endTime":480.54,"body":"probably aren't that many people"},{"speaker":"John Simboli","startTime":480.54,"endTime":484.56,"body":"who come from strong PhD"},{"speaker":"John Simboli","startTime":480.54,"endTime":484.56,"body":"background in statistics. So how"},{"speaker":"John Simboli","startTime":484.56,"endTime":488.385,"body":"does having expertise in"},{"speaker":"John Simboli","startTime":484.56,"endTime":488.385,"body":"statistics? How does that play"},{"speaker":"John Simboli","startTime":488.385,"endTime":489.825,"body":"into your ability to lead?"},{"speaker":"Stacy Lindborg","startTime":490.305,"endTime":493.005,"body":"I think it plays"},{"speaker":"Stacy Lindborg","startTime":490.305,"endTime":493.005,"body":"in significantly. And I you"},{"speaker":"Stacy Lindborg","startTime":493.005,"endTime":496.305,"body":"know, as I look across my"},{"speaker":"Stacy Lindborg","startTime":493.005,"endTime":496.305,"body":"career, I would say, starting"},{"speaker":"Stacy Lindborg","startTime":496.305,"endTime":500.865,"body":"out, you know, a degree in"},{"speaker":"Stacy Lindborg","startTime":496.305,"endTime":500.865,"body":"statistics is a very core job."},{"speaker":"Stacy Lindborg","startTime":501.285,"endTime":505.665,"body":"There is a broad need, but it's"},{"speaker":"Stacy Lindborg","startTime":501.285,"endTime":505.665,"body":"focused on direct application."},{"speaker":"Stacy Lindborg","startTime":505.665,"endTime":509.43,"body":"So you know, when I think about"},{"speaker":"Stacy Lindborg","startTime":505.665,"endTime":509.43,"body":"designing experiments, knowing"},{"speaker":"Stacy Lindborg","startTime":509.43,"endTime":512.79,"body":"how to interpret data, knowing"},{"speaker":"Stacy Lindborg","startTime":509.43,"endTime":512.79,"body":"how to understand what the FDA"},{"speaker":"Stacy Lindborg","startTime":512.79,"endTime":516.63,"body":"expects, there are so many"},{"speaker":"Stacy Lindborg","startTime":512.79,"endTime":516.63,"body":"aspects where you can actually"},{"speaker":"Stacy Lindborg","startTime":516.63,"endTime":520.17,"body":"bring innovation and bring"},{"speaker":"Stacy Lindborg","startTime":516.63,"endTime":520.17,"body":"precision and efficiency to the"},{"speaker":"Stacy Lindborg","startTime":520.17,"endTime":524.31,"body":"drug development side. When I"},{"speaker":"Stacy Lindborg","startTime":520.17,"endTime":524.31,"body":"think about even some of the"},{"speaker":"Stacy Lindborg","startTime":524.31,"endTime":528.63,"body":"more interesting kind of"},{"speaker":"Stacy Lindborg","startTime":524.31,"endTime":528.63,"body":"perspectives, like when I was in"},{"speaker":"Stacy Lindborg","startTime":528.63,"endTime":533.475,"body":"the R\u0026D strategy role at Lilly,"},{"speaker":"Stacy Lindborg","startTime":528.63,"endTime":533.475,"body":"my knowledge of how the company"},{"speaker":"Stacy Lindborg","startTime":533.475,"endTime":536.835,"body":"made decisions for an individual"},{"speaker":"Stacy Lindborg","startTime":533.475,"endTime":536.835,"body":"product at a Protocol Review"},{"speaker":"Stacy Lindborg","startTime":536.835,"endTime":541.095,"body":"Committee, you're optimizing a"},{"speaker":"Stacy Lindborg","startTime":536.835,"endTime":541.095,"body":"product. As a company, we were"},{"speaker":"Stacy Lindborg","startTime":541.095,"endTime":545.115,"body":"trying to optimize a very broad"},{"speaker":"Stacy Lindborg","startTime":541.095,"endTime":545.115,"body":"portfolio. And because I"},{"speaker":"Stacy Lindborg","startTime":545.115,"endTime":548.235,"body":"understood what it was like to"},{"speaker":"Stacy Lindborg","startTime":545.115,"endTime":548.235,"body":"hear a governance committee have"},{"speaker":"Stacy Lindborg","startTime":548.235,"endTime":551.955,"body":"a decision around, how do we"},{"speaker":"Stacy Lindborg","startTime":548.235,"endTime":551.955,"body":"optimize this indication, this,"},{"speaker":"Stacy Lindborg","startTime":552.375,"endTime":556.5,"body":"you know, this protocol in a"},{"speaker":"Stacy Lindborg","startTime":552.375,"endTime":556.5,"body":"string of protocols, and then"},{"speaker":"Stacy Lindborg","startTime":556.5,"endTime":559.92,"body":"step back and look at, how do"},{"speaker":"Stacy Lindborg","startTime":556.5,"endTime":559.92,"body":"you optimally produce as many"},{"speaker":"Stacy Lindborg","startTime":560.22,"endTime":564.18,"body":"products as possible. I actually"},{"speaker":"Stacy Lindborg","startTime":560.22,"endTime":564.18,"body":"realized we were answering and"},{"speaker":"Stacy Lindborg","startTime":564.18,"endTime":567.0,"body":"solving for the wrong problem."},{"speaker":"Stacy Lindborg","startTime":564.18,"endTime":567.0,"body":"It turned out to be a great"},{"speaker":"Stacy Lindborg","startTime":567.0,"endTime":571.74,"body":"Nature paper, that publication"},{"speaker":"Stacy Lindborg","startTime":567.0,"endTime":571.74,"body":"that followed a really"},{"speaker":"Stacy Lindborg","startTime":571.74,"endTime":575.7,"body":"preeminent Nature manuscript"},{"speaker":"Stacy Lindborg","startTime":571.74,"endTime":575.7,"body":"that Steven Paul he was head of"},{"speaker":"Stacy Lindborg","startTime":575.7,"endTime":581.385,"body":"R\u0026D, really it encompassed"},{"speaker":"Stacy Lindborg","startTime":575.7,"endTime":581.385,"body":"learnings of productivity"},{"speaker":"Stacy Lindborg","startTime":581.385,"endTime":584.445,"body":"through the lens of drug"},{"speaker":"Stacy Lindborg","startTime":581.385,"endTime":584.445,"body":"development over many years for"},{"speaker":"Stacy Lindborg","startTime":584.445,"endTime":589.725,"body":"Lilly and had some really great"},{"speaker":"Stacy Lindborg","startTime":584.445,"endTime":589.725,"body":"collaborators as authors. I came"},{"speaker":"Stacy Lindborg","startTime":589.725,"endTime":593.625,"body":"in kind of at the tail end. But"},{"speaker":"Stacy Lindborg","startTime":589.725,"endTime":593.625,"body":"you know, at the end of the day,"},{"speaker":"Stacy Lindborg","startTime":593.685,"endTime":596.625,"body":"we have to be able to grapple"},{"speaker":"Stacy Lindborg","startTime":593.685,"endTime":596.625,"body":"with uncertainty. When you think"},{"speaker":"Stacy Lindborg","startTime":596.625,"endTime":600.51,"body":"about, as a CEO, you have to be"},{"speaker":"Stacy Lindborg","startTime":596.625,"endTime":600.51,"body":"able to know where your. risks"},{"speaker":"Stacy Lindborg","startTime":600.51,"endTime":605.55,"body":"are. A lot of that is inherent"},{"speaker":"Stacy Lindborg","startTime":600.51,"endTime":605.55,"body":"with Bayesian thinking and"},{"speaker":"Stacy Lindborg","startTime":605.55,"endTime":611.37,"body":"ultimately being able to truly"},{"speaker":"Stacy Lindborg","startTime":605.55,"endTime":611.37,"body":"parse out assumptions. Really"},{"speaker":"Stacy Lindborg","startTime":611.37,"endTime":614.31,"body":"look at, you know, the"},{"speaker":"Stacy Lindborg","startTime":611.37,"endTime":614.31,"body":"historical evidence for things"},{"speaker":"Stacy Lindborg","startTime":614.31,"endTime":617.49,"body":"that maybe influence your"},{"speaker":"Stacy Lindborg","startTime":614.31,"endTime":617.49,"body":"decisions. I mean, decision"},{"speaker":"Stacy Lindborg","startTime":617.49,"endTime":620.79,"body":"theory alone, oftentimes, is"},{"speaker":"Stacy Lindborg","startTime":617.49,"endTime":620.79,"body":"bringing out assumptions that"},{"speaker":"Stacy Lindborg","startTime":620.79,"endTime":623.715,"body":"maybe we have in our heads, but"},{"speaker":"Stacy Lindborg","startTime":620.79,"endTime":623.715,"body":"we aren't verbalizing. And you"},{"speaker":"Stacy Lindborg","startTime":623.715,"endTime":626.175,"body":"you think about putting a team"},{"speaker":"Stacy Lindborg","startTime":623.715,"endTime":626.175,"body":"together in the way the"},{"speaker":"Stacy Lindborg","startTime":626.175,"endTime":630.375,"body":"conversation goes. I mean, I"},{"speaker":"Stacy Lindborg","startTime":626.175,"endTime":630.375,"body":"think, you know, again, there's"},{"speaker":"Stacy Lindborg","startTime":630.375,"endTime":634.575,"body":"a core component that's so"},{"speaker":"Stacy Lindborg","startTime":630.375,"endTime":634.575,"body":"critical. We all need to have"},{"speaker":"Stacy Lindborg","startTime":634.575,"endTime":637.875,"body":"something that we really get"},{"speaker":"Stacy Lindborg","startTime":634.575,"endTime":637.875,"body":"about our business and my"},{"speaker":"Stacy Lindborg","startTime":638.355,"endTime":642.015,"body":"training puts me in a very"},{"speaker":"Stacy Lindborg","startTime":638.355,"endTime":642.015,"body":"natural place, especially for"},{"speaker":"Stacy Lindborg","startTime":642.015,"endTime":645.615,"body":"Immunon In phase 3, and really"},{"speaker":"Stacy Lindborg","startTime":642.015,"endTime":645.615,"body":"understanding the novelty of"},{"speaker":"Stacy Lindborg","startTime":645.615,"endTime":648.9,"body":"what we can bring forward in our"},{"speaker":"Stacy Lindborg","startTime":645.615,"endTime":648.9,"body":"plans and how we can expect"},{"speaker":"Stacy Lindborg","startTime":649.08,"endTime":653.16,"body":"regulators to react, but I"},{"speaker":"Stacy Lindborg","startTime":649.08,"endTime":653.16,"body":"think, more broadly, actually,"},{"speaker":"Stacy Lindborg","startTime":653.16,"endTime":657.18,"body":"my ability to dig in and know"},{"speaker":"Stacy Lindborg","startTime":653.16,"endTime":657.18,"body":"what a trial design can't even"},{"speaker":"Stacy Lindborg","startTime":657.18,"endTime":662.4,"body":"answer. It helps me as a CEO to"},{"speaker":"Stacy Lindborg","startTime":657.18,"endTime":662.4,"body":"really think more broadly about"},{"speaker":"Stacy Lindborg","startTime":662.4,"endTime":665.94,"body":"how we go beyond the basic"},{"speaker":"Stacy Lindborg","startTime":662.4,"endTime":665.94,"body":"conclusions that ultimately come"},{"speaker":"Stacy Lindborg","startTime":665.94,"endTime":669.165,"body":"from it and just ask the bigger"},{"speaker":"Stacy Lindborg","startTime":665.94,"endTime":669.165,"body":"questions that we need to"},{"speaker":"Stacy Lindborg","startTime":669.165,"endTime":669.825,"body":"address."},{"speaker":"John Simboli","startTime":670.545,"endTime":672.105,"body":"What were the"},{"speaker":"John Simboli","startTime":670.545,"endTime":672.105,"body":"things when you first learned"},{"speaker":"John Simboli","startTime":672.105,"endTime":675.345,"body":"about the possibility that"},{"speaker":"John Simboli","startTime":672.105,"endTime":675.345,"body":"Immune on might be a place that"},{"speaker":"John Simboli","startTime":675.345,"endTime":678.285,"body":"you might might be interested in"},{"speaker":"John Simboli","startTime":675.345,"endTime":678.285,"body":"you? You might be interested in"},{"speaker":"John Simboli","startTime":678.285,"endTime":681.825,"body":"it. Can you recall what it was"},{"speaker":"John Simboli","startTime":678.285,"endTime":681.825,"body":"that you said, yeah, this is"},{"speaker":"John Simboli","startTime":681.825,"endTime":683.145,"body":"really interesting to me?"},{"speaker":"Stacy Lindborg","startTime":683.565,"endTime":688.785,"body":"I had an inside"},{"speaker":"Stacy Lindborg","startTime":683.565,"endTime":688.785,"body":"track on the company. So I was"},{"speaker":"Stacy Lindborg","startTime":688.785,"endTime":693.75,"body":"recruited to be on the board by"},{"speaker":"Stacy Lindborg","startTime":688.785,"endTime":693.75,"body":"our, at the time, our executive"},{"speaker":"Stacy Lindborg","startTime":693.75,"endTime":699.15,"body":"chairman, Michael Tardugno, was"},{"speaker":"Stacy Lindborg","startTime":693.75,"endTime":699.15,"body":"the CEO, and I joined on the"},{"speaker":"Stacy Lindborg","startTime":699.15,"endTime":704.31,"body":"board about three years before."},{"speaker":"Stacy Lindborg","startTime":699.15,"endTime":704.31,"body":"I think it was June 2021. And so"},{"speaker":"Stacy Lindborg","startTime":704.31,"endTime":707.61,"body":"I had, you know, three years of"},{"speaker":"Stacy Lindborg","startTime":704.31,"endTime":707.61,"body":"learning about the technology,"},{"speaker":"Stacy Lindborg","startTime":707.61,"endTime":711.45,"body":"understanding the science,"},{"speaker":"Stacy Lindborg","startTime":707.61,"endTime":711.45,"body":"seeing how strong of a culture"},{"speaker":"Stacy Lindborg","startTime":711.81,"endTime":715.395,"body":"the company had, a positive"},{"speaker":"Stacy Lindborg","startTime":711.81,"endTime":715.395,"body":"culture, a nimbleness, the"},{"speaker":"Stacy Lindborg","startTime":715.395,"endTime":718.215,"body":"talent that would come into the"},{"speaker":"Stacy Lindborg","startTime":715.395,"endTime":718.215,"body":"boardroom, that would be"},{"speaker":"Stacy Lindborg","startTime":718.215,"endTime":724.155,"body":"presenting. And so there was"},{"speaker":"Stacy Lindborg","startTime":718.215,"endTime":724.155,"body":"this very natural insight, you"},{"speaker":"Stacy Lindborg","startTime":724.155,"endTime":727.935,"body":"know, that was very attractive."},{"speaker":"Stacy Lindborg","startTime":724.155,"endTime":727.935,"body":"And when Mr. Tardugno approached"},{"speaker":"Stacy Lindborg","startTime":727.935,"endTime":733.215,"body":"me, he was supporting my"},{"speaker":"Stacy Lindborg","startTime":727.935,"endTime":733.215,"body":"transition, you know, to CEO. He"},{"speaker":"Stacy Lindborg","startTime":733.935,"endTime":739.62,"body":"had retired, and we had a need"},{"speaker":"Stacy Lindborg","startTime":733.935,"endTime":739.62,"body":"we weren't expecting to need to"},{"speaker":"Stacy Lindborg","startTime":739.62,"endTime":744.06,"body":"fill. I think when you have"},{"speaker":"Stacy Lindborg","startTime":739.62,"endTime":744.06,"body":"trusted relationships, you also"},{"speaker":"Stacy Lindborg","startTime":744.06,"endTime":748.92,"body":"know that you have a shared"},{"speaker":"Stacy Lindborg","startTime":744.06,"endTime":748.92,"body":"vision of what we can do and"},{"speaker":"Stacy Lindborg","startTime":748.92,"endTime":753.54,"body":"really the opportunity that"},{"speaker":"Stacy Lindborg","startTime":748.92,"endTime":753.54,"body":"stands before us. I felt that"},{"speaker":"Stacy Lindborg","startTime":753.9,"endTime":757.62,"body":"Michael's insight into, you"},{"speaker":"Stacy Lindborg","startTime":753.9,"endTime":757.62,"body":"know, the potential really just"},{"speaker":"Stacy Lindborg","startTime":757.62,"endTime":761.385,"body":"aligned so perfectly with mine"},{"speaker":"Stacy Lindborg","startTime":757.62,"endTime":761.385,"body":"and and it was such a phenomenal"},{"speaker":"Stacy Lindborg","startTime":761.385,"endTime":765.105,"body":"environment that I, unlike many"},{"speaker":"Stacy Lindborg","startTime":761.385,"endTime":765.105,"body":"other positions, you know, if"},{"speaker":"Stacy Lindborg","startTime":765.105,"endTime":768.165,"body":"you're taking something where"},{"speaker":"Stacy Lindborg","startTime":765.105,"endTime":768.165,"body":"you're just interviewing, you"},{"speaker":"Stacy Lindborg","startTime":768.165,"endTime":771.285,"body":"really don't know what you don't"},{"speaker":"Stacy Lindborg","startTime":768.165,"endTime":771.285,"body":"know. I came into this really,"},{"speaker":"Stacy Lindborg","startTime":771.345,"endTime":775.185,"body":"with a very clear expectation"},{"speaker":"Stacy Lindborg","startTime":771.345,"endTime":775.185,"body":"that really that played out, I"},{"speaker":"Stacy Lindborg","startTime":775.185,"endTime":777.165,"body":"think, very similar to what I"},{"speaker":"Stacy Lindborg","startTime":775.185,"endTime":777.165,"body":"expected."},{"speaker":"John Simboli","startTime":777.585,"endTime":781.965,"body":"This idea about a"},{"speaker":"John Simboli","startTime":777.585,"endTime":781.965,"body":"statistical background and how"},{"speaker":"John Simboli","startTime":781.965,"endTime":785.73,"body":"it would play out. I'm curious,"},{"speaker":"John Simboli","startTime":781.965,"endTime":785.73,"body":"what did you see yourself"},{"speaker":"John Simboli","startTime":785.79,"endTime":788.07,"body":"becoming, and did you become"},{"speaker":"John Simboli","startTime":785.79,"endTime":788.07,"body":"that?"},{"speaker":"Unknown","startTime":788.49,"endTime":792.87,"body":"My mom told me for my"},{"speaker":"Unknown","startTime":788.49,"endTime":792.87,"body":"early years, every time she"},{"speaker":"Unknown","startTime":792.87,"endTime":796.65,"body":"would ask, my answer was that I"},{"speaker":"Unknown","startTime":792.87,"endTime":796.65,"body":"wanted to be a mom. And I think"},{"speaker":"Unknown","startTime":796.65,"endTime":799.47,"body":"a lot of that was influenced by"},{"speaker":"Unknown","startTime":796.65,"endTime":799.47,"body":"the fact that my mom was a stay"},{"speaker":"Unknown","startTime":799.47,"endTime":803.73,"body":"at home mom. So it was what I"},{"speaker":"Unknown","startTime":799.47,"endTime":803.73,"body":"saw. It's interesting, because I"},{"speaker":"Unknown","startTime":803.73,"endTime":807.555,"body":"am blessed to be a mom. I have"},{"speaker":"Unknown","startTime":803.73,"endTime":807.555,"body":"two children, and I honestly"},{"speaker":"Unknown","startTime":807.555,"endTime":811.215,"body":"think that in the process of"},{"speaker":"Unknown","startTime":807.555,"endTime":811.215,"body":"becoming a mom, as I went"},{"speaker":"Unknown","startTime":811.215,"endTime":817.395,"body":"through my early career, with no"},{"speaker":"Unknown","startTime":811.215,"endTime":817.395,"body":"constraints, loving working,"},{"speaker":"Unknown","startTime":817.395,"endTime":820.635,"body":"working very hard, you didn't"},{"speaker":"Unknown","startTime":817.395,"endTime":820.635,"body":"really have to think about"},{"speaker":"Unknown","startTime":820.815,"endTime":823.755,"body":"intentionality of how you spent"},{"speaker":"Unknown","startTime":820.815,"endTime":823.755,"body":"your time, and it was easy to"},{"speaker":"Unknown","startTime":823.755,"endTime":828.255,"body":"give more time. And I enjoyed"},{"speaker":"Unknown","startTime":823.755,"endTime":828.255,"body":"it. Always loved what I've done,"},{"speaker":"Unknown","startTime":828.255,"endTime":831.18,"body":"and you know, honestly, it's"},{"speaker":"Unknown","startTime":828.255,"endTime":831.18,"body":"such an honor to get to"},{"speaker":"Unknown","startTime":831.18,"endTime":834.96,"body":"contribute in this sector, in"},{"speaker":"Unknown","startTime":831.18,"endTime":834.96,"body":"this field. But I found that"},{"speaker":"Unknown","startTime":834.96,"endTime":840.48,"body":"after I had kids, I knew in kind"},{"speaker":"Unknown","startTime":834.96,"endTime":840.48,"body":"of my heart and this actually, I"},{"speaker":"Unknown","startTime":840.48,"endTime":844.26,"body":"had a very direct conversation"},{"speaker":"Unknown","startTime":840.48,"endTime":844.26,"body":"with somebody very senior in one"},{"speaker":"Unknown","startTime":844.26,"endTime":848.28,"body":"of the companies I worked for."},{"speaker":"Unknown","startTime":844.26,"endTime":848.28,"body":"My job had a little bit of"},{"speaker":"Unknown","startTime":848.46,"endTime":852.78,"body":"flexibility in it, and he was"},{"speaker":"Unknown","startTime":848.46,"endTime":852.78,"body":"trying to convince me, you know,"},{"speaker":"Unknown","startTime":852.825,"endTime":855.285,"body":"don't worry about it. If you"},{"speaker":"Unknown","startTime":852.825,"endTime":855.285,"body":"have a light Friday afternoon,"},{"speaker":"Unknown","startTime":855.285,"endTime":859.545,"body":"just enjoy it. Take the time."},{"speaker":"Unknown","startTime":855.285,"endTime":859.545,"body":"And I it really crystallized in"},{"speaker":"Unknown","startTime":859.545,"endTime":861.885,"body":"my mind that, you know, if I'm"},{"speaker":"Unknown","startTime":859.545,"endTime":861.885,"body":"going to be away from my"},{"speaker":"Unknown","startTime":861.945,"endTime":865.125,"body":"children, I really want my time"},{"speaker":"Unknown","startTime":861.945,"endTime":865.125,"body":"to count. It really mattered to"},{"speaker":"Unknown","startTime":865.125,"endTime":869.505,"body":"me, and it helped me think about"},{"speaker":"Unknown","startTime":865.125,"endTime":869.505,"body":"prioritizing the right time,"},{"speaker":"Unknown","startTime":869.505,"endTime":872.745,"body":"making time for them, but then"},{"speaker":"Unknown","startTime":869.505,"endTime":872.745,"body":"really wanting to make a"},{"speaker":"Unknown","startTime":872.745,"endTime":877.95,"body":"difference in my job. And when I"},{"speaker":"Unknown","startTime":872.745,"endTime":877.95,"body":"now connect it to my current"},{"speaker":"Unknown","startTime":877.95,"endTime":881.85,"body":"job, where I'm working in a"},{"speaker":"Unknown","startTime":877.95,"endTime":881.85,"body":"field that is targeting, our"},{"speaker":"Unknown","startTime":881.85,"endTime":884.79,"body":"first indication is focused on"},{"speaker":"Unknown","startTime":881.85,"endTime":884.79,"body":"ovarian cancer. It's women's"},{"speaker":"Unknown","startTime":884.79,"endTime":890.07,"body":"health. When I talk to women"},{"speaker":"Unknown","startTime":884.79,"endTime":890.07,"body":"that are battling ovarian"},{"speaker":"Unknown","startTime":890.07,"endTime":893.61,"body":"cancer, I was at a walk very"},{"speaker":"Unknown","startTime":890.07,"endTime":893.61,"body":"recently, led by the National"},{"speaker":"Unknown","startTime":893.67,"endTime":897.45,"body":"Ovarian Cancer Coalition, and a"},{"speaker":"Unknown","startTime":893.67,"endTime":897.45,"body":"few women were willing, they"},{"speaker":"Unknown","startTime":897.45,"endTime":900.375,"body":"were kind enough to share their"},{"speaker":"Unknown","startTime":897.45,"endTime":900.375,"body":"stories with me. And they both"},{"speaker":"Unknown","startTime":900.375,"endTime":903.735,"body":"happened to have genetic"},{"speaker":"Unknown","startTime":900.375,"endTime":903.735,"body":"mutations. Because of that,"},{"speaker":"Unknown","startTime":903.735,"endTime":907.635,"body":"their children had already been"},{"speaker":"Unknown","startTime":903.735,"endTime":907.635,"body":"tested, and they knew they had"},{"speaker":"Unknown","startTime":907.635,"endTime":913.215,"body":"cancer. And it was, I think I"},{"speaker":"Unknown","startTime":907.635,"endTime":913.215,"body":"felt it on a different level,"},{"speaker":"Unknown","startTime":913.395,"endTime":917.295,"body":"because to imagine my daughter"},{"speaker":"Unknown","startTime":913.395,"endTime":917.295,"body":"being diagnosed with ovarian"},{"speaker":"Unknown","startTime":917.295,"endTime":922.095,"body":"cancer is really different than"},{"speaker":"Unknown","startTime":917.295,"endTime":922.095,"body":"for me. So I actually think that"},{"speaker":"Unknown","startTime":922.215,"endTime":926.82,"body":"thinking about it, I actually"},{"speaker":"Unknown","startTime":922.215,"endTime":926.82,"body":"think it really makes me think"},{"speaker":"Unknown","startTime":926.82,"endTime":929.34,"body":"on a very different level. In my"},{"speaker":"Unknown","startTime":926.82,"endTime":929.34,"body":"job today."},{"speaker":"John Simboli","startTime":929.94,"endTime":932.4,"body":"W`hen someone asks"},{"speaker":"John Simboli","startTime":929.94,"endTime":932.4,"body":"you, like maybe someone you"},{"speaker":"John Simboli","startTime":932.64,"endTime":935.04,"body":"honor and trust, but someone"},{"speaker":"John Simboli","startTime":932.64,"endTime":935.04,"body":"who's not from our industry,"},{"speaker":"John Simboli","startTime":935.04,"endTime":937.26,"body":"they say, Well, what's your job?"},{"speaker":"John Simboli","startTime":935.04,"endTime":937.26,"body":"What do you do? How do you"},{"speaker":"John Simboli","startTime":937.26,"endTime":940.68,"body":"answer? When someone says, Yeah,"},{"speaker":"John Simboli","startTime":937.26,"endTime":940.68,"body":"that's really, I'm amazed by"},{"speaker":"John Simboli","startTime":940.68,"endTime":943.38,"body":"what you do. But then they said,"},{"speaker":"John Simboli","startTime":940.68,"endTime":943.38,"body":"but, but what do you do each"},{"speaker":"John Simboli","startTime":943.38,"endTime":943.92,"body":"day?"},{"speaker":"Stacy Lindborg","startTime":944.44,"endTime":947.68,"body":"Well, if you get"},{"speaker":"Stacy Lindborg","startTime":944.44,"endTime":947.68,"body":"down to that level, you're"},{"speaker":"Stacy Lindborg","startTime":947.68,"endTime":954.52,"body":"meeting with the team, talking"},{"speaker":"Stacy Lindborg","startTime":947.68,"endTime":954.52,"body":"about the near term steps. So"},{"speaker":"Stacy Lindborg","startTime":954.52,"endTime":957.58,"body":"we're in phase 3. How are our"},{"speaker":"Stacy Lindborg","startTime":954.52,"endTime":957.58,"body":"how's our site activation"},{"speaker":"Stacy Lindborg","startTime":957.58,"endTime":961.54,"body":"relative to forecast? How are"},{"speaker":"Stacy Lindborg","startTime":957.58,"endTime":961.54,"body":"patients being enrolled? You're"},{"speaker":"Stacy Lindborg","startTime":961.54,"endTime":964.96,"body":"meeting with investors. You're"},{"speaker":"Stacy Lindborg","startTime":961.54,"endTime":964.96,"body":"meeting with banks. You're"},{"speaker":"Stacy Lindborg","startTime":964.96,"endTime":969.265,"body":"ultimately I mean, when I read"},{"speaker":"Stacy Lindborg","startTime":964.96,"endTime":969.265,"body":"each quarter, when I read our"},{"speaker":"Stacy Lindborg","startTime":969.265,"endTime":973.945,"body":"quarterly, we have to formally"},{"speaker":"Stacy Lindborg","startTime":969.265,"endTime":973.945,"body":"report out our earnings. We have"},{"speaker":"Stacy Lindborg","startTime":973.945,"endTime":978.985,"body":"a formal document, a 10-Q. And"},{"speaker":"Stacy Lindborg","startTime":973.945,"endTime":978.985,"body":"every time I read it, I'm"},{"speaker":"Stacy Lindborg","startTime":978.985,"endTime":984.025,"body":"reminded that I am labeled as"},{"speaker":"Stacy Lindborg","startTime":978.985,"endTime":984.025,"body":"the chief decision making"},{"speaker":"Stacy Lindborg","startTime":984.085,"endTime":989.365,"body":"officer in the company. So we"},{"speaker":"Stacy Lindborg","startTime":984.085,"endTime":989.365,"body":"need to have a long term plan, a"},{"speaker":"Stacy Lindborg","startTime":989.365,"endTime":992.71,"body":"short term plan, and we have to"},{"speaker":"Stacy Lindborg","startTime":989.365,"endTime":992.71,"body":"have money to keep moving. And"},{"speaker":"Stacy Lindborg","startTime":992.71,"endTime":997.15,"body":"so I need to be connecting in"},{"speaker":"Stacy Lindborg","startTime":992.71,"endTime":997.15,"body":"with my leaders. I've got"},{"speaker":"Stacy Lindborg","startTime":997.15,"endTime":1001.95,"body":"phenomenal people under me that"},{"speaker":"Stacy Lindborg","startTime":997.15,"endTime":1001.95,"body":"are driving programs, but need"},{"speaker":"Stacy Lindborg","startTime":1002.01,"endTime":1005.55,"body":"to bounce ideas off of. They"},{"speaker":"Stacy Lindborg","startTime":1002.01,"endTime":1005.55,"body":"need to be able to articulate"},{"speaker":"Stacy Lindborg","startTime":1006.03,"endTime":1009.33,"body":"where we're exceeding"},{"speaker":"Stacy Lindborg","startTime":1006.03,"endTime":1009.33,"body":"expectations, where we're not,"},{"speaker":"Stacy Lindborg","startTime":1009.33,"endTime":1012.57,"body":"and what we're going to do about"},{"speaker":"Stacy Lindborg","startTime":1009.33,"endTime":1012.57,"body":"it. And then, of course, make"},{"speaker":"Stacy Lindborg","startTime":1012.57,"endTime":1017.715,"body":"sure that we pivot where needed."},{"speaker":"Stacy Lindborg","startTime":1012.57,"endTime":1017.715,"body":"But I'd say one of the more core"},{"speaker":"Stacy Lindborg","startTime":1017.715,"endTime":1021.015,"body":"components, that is a really"},{"speaker":"Stacy Lindborg","startTime":1017.715,"endTime":1021.015,"body":"central part, is making sure we"},{"speaker":"Stacy Lindborg","startTime":1021.015,"endTime":1026.535,"body":"have the resources to advance."},{"speaker":"Stacy Lindborg","startTime":1021.015,"endTime":1026.535,"body":"And what's really, really just"},{"speaker":"Stacy Lindborg","startTime":1026.955,"endTime":1030.675,"body":"thrilling with the role of a"},{"speaker":"Stacy Lindborg","startTime":1026.955,"endTime":1030.675,"body":"CEO. So we have our own internal"},{"speaker":"Stacy Lindborg","startTime":1030.675,"endTime":1036.84,"body":"CMC group based in Huntsville,"},{"speaker":"Stacy Lindborg","startTime":1030.675,"endTime":1036.84,"body":"Alabama. So I get to talk deep"},{"speaker":"Stacy Lindborg","startTime":1036.84,"endTime":1039.96,"body":"science, actually, talking about"},{"speaker":"Stacy Lindborg","startTime":1036.84,"endTime":1039.96,"body":"how we're prepping for"},{"speaker":"Stacy Lindborg","startTime":1039.96,"endTime":1043.44,"body":"commercial product and advances"},{"speaker":"Stacy Lindborg","startTime":1039.96,"endTime":1043.44,"body":"that have to happen. But we're"},{"speaker":"Stacy Lindborg","startTime":1043.44,"endTime":1046.44,"body":"actually starting, we produce"},{"speaker":"Stacy Lindborg","startTime":1043.44,"endTime":1046.44,"body":"all of the active pharmaceutical"},{"speaker":"Stacy Lindborg","startTime":1046.44,"endTime":1049.38,"body":"ingredient that now patients are"},{"speaker":"Stacy Lindborg","startTime":1046.44,"endTime":1049.38,"body":"being treated with, in our labs."},{"speaker":"Stacy Lindborg","startTime":1049.98,"endTime":1054.9,"body":"I talk finance, I talk quality,"},{"speaker":"Stacy Lindborg","startTime":1049.98,"endTime":1054.9,"body":"we talk clinical trials and"},{"speaker":"Stacy Lindborg","startTime":1054.9,"endTime":1059.1,"body":"science, new indications. I"},{"speaker":"Stacy Lindborg","startTime":1054.9,"endTime":1059.1,"body":"mean, honestly, it is just a"},{"speaker":"Stacy Lindborg","startTime":1059.145,"endTime":1064.665,"body":"thrilling opportunity to talk to"},{"speaker":"Stacy Lindborg","startTime":1059.145,"endTime":1064.665,"body":"deep experts who are passionate"},{"speaker":"Stacy Lindborg","startTime":1064.665,"endTime":1068.265,"body":"and dedicated, and we're"},{"speaker":"Stacy Lindborg","startTime":1064.665,"endTime":1068.265,"body":"pivoting between short-term and"},{"speaker":"Stacy Lindborg","startTime":1068.265,"endTime":1072.585,"body":"long-term execution strategy."},{"speaker":"Stacy Lindborg","startTime":1068.265,"endTime":1072.585,"body":"And then getting to translate"},{"speaker":"Stacy Lindborg","startTime":1072.585,"endTime":1077.205,"body":"that outside the company. So it"},{"speaker":"Stacy Lindborg","startTime":1072.585,"endTime":1077.205,"body":"really is an amazing job."},{"speaker":"John Simboli","startTime":1077.565,"endTime":1079.365,"body":"If several of"},{"speaker":"John Simboli","startTime":1077.565,"endTime":1079.365,"body":"those people you were just"},{"speaker":"John Simboli","startTime":1079.365,"endTime":1083.79,"body":"describing were in a room, and I"},{"speaker":"John Simboli","startTime":1079.365,"endTime":1083.79,"body":"would ask a question, well, what"},{"speaker":"John Simboli","startTime":1084.39,"endTime":1089.01,"body":"is it about Stacy's leadership"},{"speaker":"John Simboli","startTime":1084.39,"endTime":1089.01,"body":"style that is defining about"},{"speaker":"John Simboli","startTime":1089.01,"endTime":1092.43,"body":"her? And it makes it work. Any"},{"speaker":"John Simboli","startTime":1089.01,"endTime":1092.43,"body":"idea what people want to say?"},{"speaker":"Stacy Lindborg","startTime":1092.85,"endTime":1095.01,"body":"I will actually"},{"speaker":"Stacy Lindborg","startTime":1092.85,"endTime":1095.01,"body":"ask for feedback when I'm doing"},{"speaker":"Stacy Lindborg","startTime":1095.01,"endTime":1099.57,"body":"end of year performance reviews."},{"speaker":"Stacy Lindborg","startTime":1095.01,"endTime":1099.57,"body":"And I will encourage my team to"},{"speaker":"Stacy Lindborg","startTime":1099.57,"endTime":1104.01,"body":"always feel that if there is"},{"speaker":"Stacy Lindborg","startTime":1099.57,"endTime":1104.01,"body":"feedback, in fact, I think it's"},{"speaker":"Stacy Lindborg","startTime":1104.01,"endTime":1107.415,"body":"a way that you respect people,"},{"speaker":"Stacy Lindborg","startTime":1104.01,"endTime":1107.415,"body":"is to offer constructive"},{"speaker":"Stacy Lindborg","startTime":1107.895,"endTime":1111.015,"body":"feedback. And if you're"},{"speaker":"Stacy Lindborg","startTime":1107.895,"endTime":1111.015,"body":"communicating in a way that's"},{"speaker":"Stacy Lindborg","startTime":1111.015,"endTime":1114.315,"body":"minimizing somebody acting in a"},{"speaker":"Stacy Lindborg","startTime":1111.015,"endTime":1114.315,"body":"way that could be more powerful"},{"speaker":"Stacy Lindborg","startTime":1114.315,"endTime":1117.555,"body":"for the company,  it's a it's a"},{"speaker":"Stacy Lindborg","startTime":1114.315,"endTime":1117.555,"body":"wonderful strength. So I"},{"speaker":"Stacy Lindborg","startTime":1117.555,"endTime":1121.875,"body":"definitely have people that will"},{"speaker":"Stacy Lindborg","startTime":1117.555,"endTime":1121.875,"body":"comment on being surprised by"},{"speaker":"Stacy Lindborg","startTime":1121.875,"endTime":1126.555,"body":"the aspect of humility in my"},{"speaker":"Stacy Lindborg","startTime":1121.875,"endTime":1126.555,"body":"job, which I personally think is"},{"speaker":"Stacy Lindborg","startTime":1126.555,"endTime":1131.64,"body":"a strength, but it's it's a"},{"speaker":"Stacy Lindborg","startTime":1126.555,"endTime":1131.64,"body":"difference. I've been told, and"},{"speaker":"Stacy Lindborg","startTime":1131.64,"endTime":1135.42,"body":"I think I also aspire to this,"},{"speaker":"Stacy Lindborg","startTime":1131.64,"endTime":1135.42,"body":"that I don't ever want to ask"},{"speaker":"Stacy Lindborg","startTime":1135.42,"endTime":1139.08,"body":"something of my team that I'm"},{"speaker":"Stacy Lindborg","startTime":1135.42,"endTime":1139.08,"body":"not willing to do myself. So I"},{"speaker":"Stacy Lindborg","startTime":1139.08,"endTime":1143.1,"body":"work hard. I have very high"},{"speaker":"Stacy Lindborg","startTime":1139.08,"endTime":1143.1,"body":"expectations of myself. And I"},{"speaker":"Stacy Lindborg","startTime":1143.1,"endTime":1147.36,"body":"think we set really, you know,"},{"speaker":"Stacy Lindborg","startTime":1143.1,"endTime":1147.36,"body":"phenomenal goals that we want to"},{"speaker":"Stacy Lindborg","startTime":1147.36,"endTime":1151.08,"body":"accomplish. Those are some of"},{"speaker":"Stacy Lindborg","startTime":1147.36,"endTime":1151.08,"body":"the aspects, and I think it's"},{"speaker":"Stacy Lindborg","startTime":1151.2,"endTime":1154.005,"body":"important that we have fun. So"},{"speaker":"Stacy Lindborg","startTime":1151.2,"endTime":1154.005,"body":"we're going to work hard, but"},{"speaker":"Stacy Lindborg","startTime":1154.005,"endTime":1157.605,"body":"hopefully we laugh along the way"},{"speaker":"Stacy Lindborg","startTime":1154.005,"endTime":1157.605,"body":"and and get to know each other"},{"speaker":"Stacy Lindborg","startTime":1157.605,"endTime":1160.005,"body":"and enjoy life as we go through"},{"speaker":"Stacy Lindborg","startTime":1157.605,"endTime":1160.005,"body":"it."},{"speaker":"John Simboli","startTime":1160.845,"endTime":1162.765,"body":"In the shortest"},{"speaker":"John Simboli","startTime":1160.845,"endTime":1162.765,"body":"version that would make sense,"},{"speaker":"John Simboli","startTime":1162.765,"endTime":1166.245,"body":"when someone says who is or what"},{"speaker":"John Simboli","startTime":1162.765,"endTime":1166.245,"body":"is Immunon, how do you like to"},{"speaker":"John Simboli","startTime":1166.245,"endTime":1166.785,"body":"answer that?"},{"speaker":"Stacy Lindborg","startTime":1167.38,"endTime":1170.02,"body":"We're a clinical"},{"speaker":"Stacy Lindborg","startTime":1167.38,"endTime":1170.02,"body":"stage biotech company that's"},{"speaker":"Stacy Lindborg","startTime":1170.02,"endTime":1174.88,"body":"focusing on immunotherapies,"},{"speaker":"Stacy Lindborg","startTime":1170.02,"endTime":1174.88,"body":"novel immunotherapies that are"},{"speaker":"Stacy Lindborg","startTime":1174.88,"endTime":1178.0,"body":"harnessing our immune system,"},{"speaker":"Stacy Lindborg","startTime":1174.88,"endTime":1178.0,"body":"our natural immune system, to"},{"speaker":"Stacy Lindborg","startTime":1178.0,"endTime":1181.54,"body":"fight tough diseases."},{"speaker":"Stacy Lindborg","startTime":1178.0,"endTime":1181.54,"body":"Specifically, we have been"},{"speaker":"Stacy Lindborg","startTime":1181.54,"endTime":1186.64,"body":"focused on cancer across our"},{"speaker":"Stacy Lindborg","startTime":1181.54,"endTime":1186.64,"body":"life cycle. If I were to expand"},{"speaker":"Stacy Lindborg","startTime":1186.64,"endTime":1189.565,"body":"on that, I would talk about how"},{"speaker":"Stacy Lindborg","startTime":1186.64,"endTime":1189.565,"body":"the immunotherapy, you know what"},{"speaker":"Stacy Lindborg","startTime":1189.565,"endTime":1192.685,"body":"the approach is that we're"},{"speaker":"Stacy Lindborg","startTime":1189.565,"endTime":1192.685,"body":"using. There are lots of"},{"speaker":"Stacy Lindborg","startTime":1192.685,"endTime":1195.685,"body":"different approaches to trying"},{"speaker":"Stacy Lindborg","startTime":1192.685,"endTime":1195.685,"body":"to harness the immune system."},{"speaker":"Stacy Lindborg","startTime":1195.685,"endTime":1201.445,"body":"We're using a DNA-based plasmid"},{"speaker":"Stacy Lindborg","startTime":1195.685,"endTime":1201.445,"body":"that is using a synthetic"},{"speaker":"Stacy Lindborg","startTime":1201.445,"endTime":1205.885,"body":"carrier that basically takes the"},{"speaker":"Stacy Lindborg","startTime":1201.445,"endTime":1205.885,"body":"therapeutic and allows it to get"},{"speaker":"Stacy Lindborg","startTime":1205.885,"endTime":1211.045,"body":"into the cells of women, that's"},{"speaker":"Stacy Lindborg","startTime":1205.885,"endTime":1211.045,"body":"in our most advanced case, with"},{"speaker":"Stacy Lindborg","startTime":1211.045,"endTime":1214.33,"body":"ovarian cancer. And these cells"},{"speaker":"Stacy Lindborg","startTime":1211.045,"endTime":1214.33,"body":"are programmed to start"},{"speaker":"Stacy Lindborg","startTime":1214.33,"endTime":1217.51,"body":"releasing really important"},{"speaker":"Stacy Lindborg","startTime":1214.33,"endTime":1217.51,"body":"cytokines that would naturally"},{"speaker":"Stacy Lindborg","startTime":1217.51,"endTime":1222.43,"body":"occur in our body, and basically"},{"speaker":"Stacy Lindborg","startTime":1217.51,"endTime":1222.43,"body":"releasing the ability for our"},{"speaker":"Stacy Lindborg","startTime":1222.43,"endTime":1227.59,"body":"body to fight cancer. So we give"},{"speaker":"Stacy Lindborg","startTime":1222.43,"endTime":1227.59,"body":"it, basically, kind of a recipe"},{"speaker":"Stacy Lindborg","startTime":1227.83,"endTime":1233.35,"body":"for the body to not only see the"},{"speaker":"Stacy Lindborg","startTime":1227.83,"endTime":1233.35,"body":"tumors. So the ovarian cancer,"},{"speaker":"Stacy Lindborg","startTime":1233.35,"endTime":1235.99,"body":"which is really different than"},{"speaker":"Stacy Lindborg","startTime":1233.35,"endTime":1235.99,"body":"many other kinds of cancers, is"},{"speaker":"Stacy Lindborg","startTime":1235.99,"endTime":1240.535,"body":"immunologically cold, so the"},{"speaker":"Stacy Lindborg","startTime":1235.99,"endTime":1240.535,"body":"immune system can't see it. We"},{"speaker":"Stacy Lindborg","startTime":1240.535,"endTime":1244.795,"body":"are able to change the tumor"},{"speaker":"Stacy Lindborg","startTime":1240.535,"endTime":1244.795,"body":"micro-environment, the setting"},{"speaker":"Stacy Lindborg","startTime":1244.795,"endTime":1248.815,"body":"where the tumors are, which is"},{"speaker":"Stacy Lindborg","startTime":1244.795,"endTime":1248.815,"body":"in the peritoneal cavity, to a"},{"speaker":"Stacy Lindborg","startTime":1248.815,"endTime":1253.555,"body":"hot tumor environment, which"},{"speaker":"Stacy Lindborg","startTime":1248.815,"endTime":1253.555,"body":"allows our product to flourish."},{"speaker":"Stacy Lindborg","startTime":1253.555,"endTime":1257.695,"body":"And in fact, we know that both"},{"speaker":"Stacy Lindborg","startTime":1253.555,"endTime":1257.695,"body":"healthy cells and cancer cells,"},{"speaker":"Stacy Lindborg","startTime":1257.695,"endTime":1263.08,"body":"alike, uptake the product and"},{"speaker":"Stacy Lindborg","startTime":1257.695,"endTime":1263.08,"body":"then start producing IL-12,"},{"speaker":"Stacy Lindborg","startTime":1263.26,"endTime":1267.7,"body":"interferon gamma, TGF alpha,"},{"speaker":"Stacy Lindborg","startTime":1263.26,"endTime":1267.7,"body":"this powerful change to the"},{"speaker":"Stacy Lindborg","startTime":1267.7,"endTime":1271.84,"body":"micro-tumor environment. It's an"},{"speaker":"Stacy Lindborg","startTime":1267.7,"endTime":1271.84,"body":"amazing process. That's the goal"},{"speaker":"Stacy Lindborg","startTime":1271.84,"endTime":1275.38,"body":"of the therapy. We can actually"},{"speaker":"Stacy Lindborg","startTime":1271.84,"endTime":1275.38,"body":"measure through ascites, which"},{"speaker":"Stacy Lindborg","startTime":1275.38,"endTime":1279.04,"body":"is the fluid in the peritoneal"},{"speaker":"Stacy Lindborg","startTime":1275.38,"endTime":1279.04,"body":"cavity. We can take it out, and"},{"speaker":"Stacy Lindborg","startTime":1279.04,"endTime":1283.0,"body":"we can actually see these"},{"speaker":"Stacy Lindborg","startTime":1279.04,"endTime":1283.0,"body":"many-fold increases that the"},{"speaker":"Stacy Lindborg","startTime":1283.045,"endTime":1287.245,"body":"product is doing what we want."},{"speaker":"Stacy Lindborg","startTime":1283.045,"endTime":1287.245,"body":"We see downstream effects. And"},{"speaker":"Stacy Lindborg","startTime":1287.245,"endTime":1290.845,"body":"then when we get to clinical"},{"speaker":"Stacy Lindborg","startTime":1287.245,"endTime":1290.845,"body":"data, we can see that women, the"},{"speaker":"Stacy Lindborg","startTime":1290.845,"endTime":1295.285,"body":"median, is substantially"},{"speaker":"Stacy Lindborg","startTime":1290.845,"endTime":1295.285,"body":"improved. So we're seeing,"},{"speaker":"Stacy Lindborg","startTime":1295.525,"endTime":1298.525,"body":"really, what the Holy Grail is"},{"speaker":"Stacy Lindborg","startTime":1295.525,"endTime":1298.525,"body":"with ovarian cancer, that we're"},{"speaker":"Stacy Lindborg","startTime":1298.525,"endTime":1303.265,"body":"able to, for the first time,"},{"speaker":"Stacy Lindborg","startTime":1298.525,"endTime":1303.265,"body":"extend overall survival. A"},{"speaker":"Stacy Lindborg","startTime":1303.265,"endTime":1306.19,"body":"combination chemotherapy is the"},{"speaker":"Stacy Lindborg","startTime":1303.265,"endTime":1306.19,"body":"current standard of care. So"},{"speaker":"Stacy Lindborg","startTime":1306.67,"endTime":1311.11,"body":"more women are getting it before"},{"speaker":"Stacy Lindborg","startTime":1306.67,"endTime":1311.11,"body":"surgery. That used to be some"},{"speaker":"Stacy Lindborg","startTime":1311.11,"endTime":1314.95,"body":"were treated before surgery,"},{"speaker":"Stacy Lindborg","startTime":1311.11,"endTime":1314.95,"body":"some were treated surgery and"},{"speaker":"Stacy Lindborg","startTime":1314.95,"endTime":1318.49,"body":"then and then chemo. Really what"},{"speaker":"Stacy Lindborg","startTime":1314.95,"endTime":1318.49,"body":"we're seeing now is that if"},{"speaker":"Stacy Lindborg","startTime":1318.49,"endTime":1322.21,"body":"women can tolerate and can"},{"speaker":"Stacy Lindborg","startTime":1318.49,"endTime":1322.21,"body":"accept it, almost everybody is"},{"speaker":"Stacy Lindborg","startTime":1322.21,"endTime":1326.77,"body":"starting to now move to new"},{"speaker":"Stacy Lindborg","startTime":1322.21,"endTime":1326.77,"body":"adjuvant chemo, which allows the"},{"speaker":"Stacy Lindborg","startTime":1326.77,"endTime":1331.075,"body":"tumors to shrink. Then you can"},{"speaker":"Stacy Lindborg","startTime":1326.77,"endTime":1331.075,"body":"surgically remove more, so"},{"speaker":"Stacy Lindborg","startTime":1331.075,"endTime":1333.235,"body":"you're getting more of the"},{"speaker":"Stacy Lindborg","startTime":1331.075,"endTime":1333.235,"body":"cancer, and then they continue"},{"speaker":"Stacy Lindborg","startTime":1333.235,"endTime":1337.375,"body":"with chemotherapy. So that's the"},{"speaker":"Stacy Lindborg","startTime":1333.235,"endTime":1337.375,"body":"standard of care. If we think"},{"speaker":"Stacy Lindborg","startTime":1337.375,"endTime":1340.675,"body":"about, I'll just start with"},{"speaker":"Stacy Lindborg","startTime":1337.375,"endTime":1340.675,"body":"immunotherapies, because that's"},{"speaker":"Stacy Lindborg","startTime":1340.735,"endTime":1343.855,"body":"what our product is. So our,"},{"speaker":"Stacy Lindborg","startTime":1340.735,"endTime":1343.855,"body":"really the payload, and what"},{"speaker":"Stacy Lindborg","startTime":1343.855,"endTime":1347.695,"body":"we're really triggering the"},{"speaker":"Stacy Lindborg","startTime":1343.855,"endTime":1347.695,"body":"immune system to start producing"},{"speaker":"Stacy Lindborg","startTime":1347.695,"endTime":1352.18,"body":"is IL-12. It's a very important"},{"speaker":"Stacy Lindborg","startTime":1347.695,"endTime":1352.18,"body":"cytokine. There have been quite"},{"speaker":"Stacy Lindborg","startTime":1352.18,"endTime":1355.6,"body":"a few attempts at delivering"},{"speaker":"Stacy Lindborg","startTime":1352.18,"endTime":1355.6,"body":"IL-12, and I think a lot of it"},{"speaker":"Stacy Lindborg","startTime":1355.6,"endTime":1359.2,"body":"comes back to how is it being"},{"speaker":"Stacy Lindborg","startTime":1355.6,"endTime":1359.2,"body":"delivered. So a lot of the early"},{"speaker":"Stacy Lindborg","startTime":1359.2,"endTime":1361.72,"body":"attempts, and this even goes"},{"speaker":"Stacy Lindborg","startTime":1359.2,"endTime":1361.72,"body":"back to when immunotherapies"},{"speaker":"Stacy Lindborg","startTime":1361.72,"endTime":1365.62,"body":"were first being discovered."},{"speaker":"Stacy Lindborg","startTime":1361.72,"endTime":1365.62,"body":"IL-12 was at the heart of the"},{"speaker":"Stacy Lindborg","startTime":1365.62,"endTime":1369.46,"body":"very exciting and very"},{"speaker":"Stacy Lindborg","startTime":1365.62,"endTime":1369.46,"body":"productive evolution for cancer"},{"speaker":"Stacy Lindborg","startTime":1369.46,"endTime":1373.66,"body":"treatments that have occurred"},{"speaker":"Stacy Lindborg","startTime":1369.46,"endTime":1373.66,"body":"with many, many tumors. But with"},{"speaker":"Stacy Lindborg","startTime":1373.66,"endTime":1376.705,"body":"IL-12 in particular, many of the"},{"speaker":"Stacy Lindborg","startTime":1373.66,"endTime":1376.705,"body":"early attempts were actually"},{"speaker":"Stacy Lindborg","startTime":1376.705,"endTime":1380.965,"body":"administering recombinant 12"},{"speaker":"Stacy Lindborg","startTime":1376.705,"endTime":1380.965,"body":"directly into the blood, IV. And"},{"speaker":"Stacy Lindborg","startTime":1380.965,"endTime":1383.725,"body":"what you would see is these"},{"speaker":"Stacy Lindborg","startTime":1380.965,"endTime":1383.725,"body":"massive spikes. Actually,"},{"speaker":"Stacy Lindborg","startTime":1383.725,"endTime":1387.505,"body":"there's not a very long half"},{"speaker":"Stacy Lindborg","startTime":1383.725,"endTime":1387.505,"body":"life. There were very strong"},{"speaker":"Stacy Lindborg","startTime":1388.105,"endTime":1391.885,"body":"toxic effects. There were even"},{"speaker":"Stacy Lindborg","startTime":1388.105,"endTime":1391.885,"body":"people that died in clinical"},{"speaker":"Stacy Lindborg","startTime":1391.885,"endTime":1398.29,"body":"trials. So IL-12, while a very"},{"speaker":"Stacy Lindborg","startTime":1391.885,"endTime":1398.29,"body":"exciting, promising arena, ended"},{"speaker":"Stacy Lindborg","startTime":1398.29,"endTime":1402.19,"body":"up being very impossible to dose"},{"speaker":"Stacy Lindborg","startTime":1398.29,"endTime":1402.19,"body":"at a high enough level and do so"},{"speaker":"Stacy Lindborg","startTime":1402.19,"endTime":1408.19,"body":"safely. And what we discovered"},{"speaker":"Stacy Lindborg","startTime":1402.19,"endTime":1408.19,"body":"was a way to bring it directly"},{"speaker":"Stacy Lindborg","startTime":1408.19,"endTime":1412.57,"body":"into where the tumors are, to"},{"speaker":"Stacy Lindborg","startTime":1408.19,"endTime":1412.57,"body":"focus. That's exactly where you"},{"speaker":"Stacy Lindborg","startTime":1412.57,"endTime":1417.73,"body":"want to have the treatment. To"},{"speaker":"Stacy Lindborg","startTime":1412.57,"endTime":1417.73,"body":"allow cells to be manufacturing,"},{"speaker":"Stacy Lindborg","startTime":1417.73,"endTime":1420.49,"body":"then, this. Rather than"},{"speaker":"Stacy Lindborg","startTime":1417.73,"endTime":1420.49,"body":"delivering IL-12, we're not"},{"speaker":"Stacy Lindborg","startTime":1420.49,"endTime":1423.895,"body":"actually administering IL-12."},{"speaker":"Stacy Lindborg","startTime":1420.49,"endTime":1423.895,"body":"We're actually delivering a DNA"},{"speaker":"Stacy Lindborg","startTime":1423.895,"endTime":1427.795,"body":"plasmid that is allowing the"},{"speaker":"Stacy Lindborg","startTime":1423.895,"endTime":1427.795,"body":"body to produce it. It keeps it"},{"speaker":"Stacy Lindborg","startTime":1427.795,"endTime":1430.495,"body":"contained. We're able to show"},{"speaker":"Stacy Lindborg","startTime":1427.795,"endTime":1430.495,"body":"that we don't see systemic"},{"speaker":"Stacy Lindborg","startTime":1430.495,"endTime":1434.815,"body":"distribution. Therefore, we got"},{"speaker":"Stacy Lindborg","startTime":1430.495,"endTime":1434.815,"body":"around the safety concern. And I"},{"speaker":"Stacy Lindborg","startTime":1435.175,"endTime":1438.595,"body":"believe that because we're"},{"speaker":"Stacy Lindborg","startTime":1435.175,"endTime":1438.595,"body":"actually administering it"},{"speaker":"Stacy Lindborg","startTime":1438.955,"endTime":1443.155,"body":"inter-peritonealy, it actually"},{"speaker":"Stacy Lindborg","startTime":1438.955,"endTime":1443.155,"body":"is exactly where it needs to be."},{"speaker":"Stacy Lindborg","startTime":1443.2,"endTime":1448.36,"body":"And therefore the survival"},{"speaker":"Stacy Lindborg","startTime":1443.2,"endTime":1448.36,"body":"benefits that we see. So I think"},{"speaker":"Stacy Lindborg","startTime":1448.36,"endTime":1451.6,"body":"the delivery, the mechanism of"},{"speaker":"Stacy Lindborg","startTime":1448.36,"endTime":1451.6,"body":"how to get it into the nucleus"},{"speaker":"Stacy Lindborg","startTime":1451.6,"endTime":1455.74,"body":"of the cell, not have"},{"speaker":"Stacy Lindborg","startTime":1451.6,"endTime":1455.74,"body":"degradation of the product"},{"speaker":"Stacy Lindborg","startTime":1455.8,"endTime":1458.44,"body":"needed. There's a lot of"},{"speaker":"Stacy Lindborg","startTime":1455.8,"endTime":1458.44,"body":"technical things you had to"},{"speaker":"Stacy Lindborg","startTime":1458.44,"endTime":1463.0,"body":"overcome, but the platform"},{"speaker":"Stacy Lindborg","startTime":1458.44,"endTime":1463.0,"body":"itself is the real innovation"},{"speaker":"Stacy Lindborg","startTime":1463.0,"endTime":1465.7,"body":"and harnessing science that's"},{"speaker":"Stacy Lindborg","startTime":1463.0,"endTime":1465.7,"body":"very well established."},{"speaker":"John Simboli","startTime":1465.96,"endTime":1467.88,"body":"How big is the"},{"speaker":"John Simboli","startTime":1465.96,"endTime":1467.88,"body":"scope of the problem?"},{"speaker":"Unknown","startTime":1467.0,"endTime":1472.46,"body":"In the US, 20,000 women"},{"speaker":"Unknown","startTime":1467.0,"endTime":1472.46,"body":"are diagnosed every year, and we"},{"speaker":"Unknown","startTime":1472.46,"endTime":1477.14,"body":"see about, pretty consistently,"},{"speaker":"Unknown","startTime":1472.46,"endTime":1477.14,"body":"13,000 deaths. At a worldwide"},{"speaker":"Unknown","startTime":1477.14,"endTime":1483.44,"body":"level, it's 300,000 newly"},{"speaker":"Unknown","startTime":1477.14,"endTime":1483.44,"body":"diagnosed. So it is a very"},{"speaker":"Unknown","startTime":1483.5,"endTime":1487.16,"body":"stable and unfortunate, you"},{"speaker":"Unknown","startTime":1483.5,"endTime":1487.16,"body":"know, kind of picture that we're"},{"speaker":"Unknown","startTime":1487.16,"endTime":1491.54,"body":"seeing over time. It's a"},{"speaker":"Unknown","startTime":1487.16,"endTime":1491.54,"body":"chronic, it's one of the cancers"},{"speaker":"Unknown","startTime":1491.585,"endTime":1495.185,"body":"that we really have seen, we've"},{"speaker":"Unknown","startTime":1491.585,"endTime":1495.185,"body":"seen progress in the later"},{"speaker":"Unknown","startTime":1495.245,"endTime":1497.945,"body":"treatment phases, but not in"},{"speaker":"Unknown","startTime":1495.245,"endTime":1497.945,"body":"front line. And it is, it's"},{"speaker":"Unknown","startTime":1497.945,"endTime":1499.505,"body":"time. It's really needed."},{"speaker":"John Simboli","startTime":1500.02,"endTime":1502.96,"body":"The data will tell"},{"speaker":"John Simboli","startTime":1500.02,"endTime":1502.96,"body":"you, and the science will tell"},{"speaker":"John Simboli","startTime":1502.96,"endTime":1505.66,"body":"you what's next and where you"},{"speaker":"John Simboli","startTime":1502.96,"endTime":1505.66,"body":"go. But at this stage, do you"},{"speaker":"John Simboli","startTime":1505.66,"endTime":1508.42,"body":"allow yourself to think, Oh, if"},{"speaker":"John Simboli","startTime":1505.66,"endTime":1508.42,"body":"this succeeds the way I hope it"},{"speaker":"John Simboli","startTime":1508.42,"endTime":1511.96,"body":"will, or the way I think that it"},{"speaker":"John Simboli","startTime":1508.42,"endTime":1511.96,"body":"will, it'll have this effect."},{"speaker":"John Simboli","startTime":1511.96,"endTime":1514.24,"body":"What effect do you permit"},{"speaker":"John Simboli","startTime":1511.96,"endTime":1514.24,"body":"yourself to consider?"},{"speaker":"Stacy Lindborg","startTime":1514.36,"endTime":1517.0,"body":"We intend to"},{"speaker":"Stacy Lindborg","startTime":1514.36,"endTime":1517.0,"body":"transform the standard of care"},{"speaker":"Stacy Lindborg","startTime":1517.0,"endTime":1520.06,"body":"in frontline ovarian cancer. And"},{"speaker":"Stacy Lindborg","startTime":1517.0,"endTime":1520.06,"body":"it's very clear, if we replicate"},{"speaker":"Stacy Lindborg","startTime":1520.06,"endTime":1523.84,"body":"the findings from Phase 2, that"},{"speaker":"Stacy Lindborg","startTime":1520.06,"endTime":1523.84,"body":"will happen. I mean extending,"},{"speaker":"Stacy Lindborg","startTime":1523.84,"endTime":1529.96,"body":"so the five year survival rate"},{"speaker":"Stacy Lindborg","startTime":1523.84,"endTime":1529.96,"body":"is less than 40% and so if"},{"speaker":"Stacy Lindborg","startTime":1529.96,"endTime":1535.42,"body":"you're able to show that the"},{"speaker":"Stacy Lindborg","startTime":1529.96,"endTime":1535.42,"body":"median extension in this trial"},{"speaker":"Stacy Lindborg","startTime":1535.42,"endTime":1539.845,"body":"is 13 months. I mean, in that"},{"speaker":"Stacy Lindborg","startTime":1535.42,"endTime":1539.845,"body":"context, it's very, very"},{"speaker":"Stacy Lindborg","startTime":1539.845,"endTime":1544.405,"body":"critical. So the best chance you"},{"speaker":"Stacy Lindborg","startTime":1539.845,"endTime":1544.405,"body":"have at a cure is right when"},{"speaker":"Stacy Lindborg","startTime":1544.405,"endTime":1549.025,"body":"you're newly diagnosed. Hitting"},{"speaker":"Stacy Lindborg","startTime":1544.405,"endTime":1549.025,"body":"the earliest time point that"},{"speaker":"Stacy Lindborg","startTime":1549.025,"endTime":1552.865,"body":"you're aware that the cancer is"},{"speaker":"Stacy Lindborg","startTime":1549.025,"endTime":1552.865,"body":"there. And you know, this is a"},{"speaker":"Stacy Lindborg","startTime":1552.865,"endTime":1556.165,"body":"place where Immunon is really"},{"speaker":"Stacy Lindborg","startTime":1552.865,"endTime":1556.165,"body":"different from, if you look at"},{"speaker":"Stacy Lindborg","startTime":1556.165,"endTime":1559.405,"body":"the standard development path"},{"speaker":"Stacy Lindborg","startTime":1556.165,"endTime":1559.405,"body":"for, and I'll just stay with"},{"speaker":"Stacy Lindborg","startTime":1559.405,"endTime":1564.55,"body":"ovarian cancer for now, you"},{"speaker":"Stacy Lindborg","startTime":1559.405,"endTime":1564.55,"body":"know, it is somewhat easier and"},{"speaker":"Stacy Lindborg","startTime":1564.73,"endTime":1569.89,"body":"a maybe a more likely to succeed"},{"speaker":"Stacy Lindborg","startTime":1564.73,"endTime":1569.89,"body":"plan to go after a following,"},{"speaker":"Stacy Lindborg","startTime":1569.89,"endTime":1572.83,"body":"you know, second or third line,"},{"speaker":"Stacy Lindborg","startTime":1569.89,"endTime":1572.83,"body":"or to even go in the maintenance"},{"speaker":"Stacy Lindborg","startTime":1572.83,"endTime":1576.97,"body":"period. And when you look at"},{"speaker":"Stacy Lindborg","startTime":1572.83,"endTime":1576.97,"body":"those protocols, what you're"},{"speaker":"Stacy Lindborg","startTime":1577.03,"endTime":1580.69,"body":"usually requiring is that the"},{"speaker":"Stacy Lindborg","startTime":1577.03,"endTime":1580.69,"body":"patient has responded to the"},{"speaker":"Stacy Lindborg","startTime":1580.69,"endTime":1584.635,"body":"frontline treatment. So we know"},{"speaker":"Stacy Lindborg","startTime":1580.69,"endTime":1584.635,"body":"that there is a percentage of"},{"speaker":"Stacy Lindborg","startTime":1584.635,"endTime":1589.495,"body":"women that will not respond to"},{"speaker":"Stacy Lindborg","startTime":1584.635,"endTime":1589.495,"body":"chemotherapy, and therefore they"},{"speaker":"Stacy Lindborg","startTime":1589.495,"endTime":1592.495,"body":"would not contribute to learning"},{"speaker":"Stacy Lindborg","startTime":1589.495,"endTime":1592.495,"body":"about a product. They would,"},{"speaker":"Stacy Lindborg","startTime":1592.495,"endTime":1596.275,"body":"unfortunately, are just going to"},{"speaker":"Stacy Lindborg","startTime":1592.495,"endTime":1596.275,"body":"have worse outcomes. When you're"},{"speaker":"Stacy Lindborg","startTime":1596.275,"endTime":1599.095,"body":"studying frontline you're"},{"speaker":"Stacy Lindborg","startTime":1596.275,"endTime":1599.095,"body":"getting everybody you don't know"},{"speaker":"Stacy Lindborg","startTime":1599.095,"endTime":1602.335,"body":"who's going to respond. It is a"},{"speaker":"Stacy Lindborg","startTime":1599.095,"endTime":1602.335,"body":"riskier proposition, and it's a"},{"speaker":"Stacy Lindborg","startTime":1602.335,"endTime":1606.055,"body":"harder space. This is what I'm"},{"speaker":"Stacy Lindborg","startTime":1602.335,"endTime":1606.055,"body":"learning from gynecological"},{"speaker":"Stacy Lindborg","startTime":1606.055,"endTime":1609.46,"body":"oncologists. Simply because"},{"speaker":"Stacy Lindborg","startTime":1606.055,"endTime":1609.46,"body":"they're very sick, they're very"},{"speaker":"Stacy Lindborg","startTime":1609.46,"endTime":1613.3,"body":"frail, there's a very strong"},{"speaker":"Stacy Lindborg","startTime":1609.46,"endTime":1613.3,"body":"burden of cancer. We know that"},{"speaker":"Stacy Lindborg","startTime":1613.3,"endTime":1616.42,"body":"80% of women are diagnosed in"},{"speaker":"Stacy Lindborg","startTime":1613.3,"endTime":1616.42,"body":"late stage, because you don't"},{"speaker":"Stacy Lindborg","startTime":1616.42,"endTime":1620.08,"body":"have distinct symptoms,"},{"speaker":"Stacy Lindborg","startTime":1616.42,"endTime":1620.08,"body":"therefore for diagnoses to"},{"speaker":"Stacy Lindborg","startTime":1620.08,"endTime":1624.04,"body":"occur. And so, but it's also one"},{"speaker":"Stacy Lindborg","startTime":1620.08,"endTime":1624.04,"body":"of the most exciting things. It"},{"speaker":"Stacy Lindborg","startTime":1624.04,"endTime":1627.16,"body":"was a really bold move for the"},{"speaker":"Stacy Lindborg","startTime":1624.04,"endTime":1627.16,"body":"company when we decided"},{"speaker":"Stacy Lindborg","startTime":1627.22,"endTime":1632.065,"body":"frontline was the way to go. And"},{"speaker":"Stacy Lindborg","startTime":1627.22,"endTime":1632.065,"body":"if I tie this back to where do I"},{"speaker":"Stacy Lindborg","startTime":1632.065,"endTime":1635.785,"body":"hope we'll be, you know, right"},{"speaker":"Stacy Lindborg","startTime":1632.065,"endTime":1635.785,"body":"now, we're studying a relatively"},{"speaker":"Stacy Lindborg","startTime":1635.785,"endTime":1639.745,"body":"short treatment course. So the"},{"speaker":"Stacy Lindborg","startTime":1635.785,"endTime":1639.745,"body":"weekly doses that are given in"},{"speaker":"Stacy Lindborg","startTime":1639.745,"endTime":1644.305,"body":"phase 2 and now in phase 3,"},{"speaker":"Stacy Lindborg","startTime":1639.745,"endTime":1644.305,"body":"really amount to six months of"},{"speaker":"Stacy Lindborg","startTime":1644.305,"endTime":1647.365,"body":"treatment. But we have women"},{"speaker":"Stacy Lindborg","startTime":1644.305,"endTime":1647.365,"body":"that are now well beyond five"},{"speaker":"Stacy Lindborg","startTime":1647.365,"endTime":1650.185,"body":"years, and we still see a"},{"speaker":"Stacy Lindborg","startTime":1647.365,"endTime":1650.185,"body":"treatment, an overriding"},{"speaker":"Stacy Lindborg","startTime":1650.185,"endTime":1654.55,"body":"treatment benefit. If you've"},{"speaker":"Stacy Lindborg","startTime":1650.185,"endTime":1654.55,"body":"already shown a propensity to"},{"speaker":"Stacy Lindborg","startTime":1654.55,"endTime":1658.21,"body":"extend life, now, what if you"},{"speaker":"Stacy Lindborg","startTime":1654.55,"endTime":1658.21,"body":"could actually do so on a much"},{"speaker":"Stacy Lindborg","startTime":1658.57,"endTime":1662.83,"body":"broader time frame, and maybe"},{"speaker":"Stacy Lindborg","startTime":1658.57,"endTime":1662.83,"body":"even in combinations with other"},{"speaker":"Stacy Lindborg","startTime":1662.83,"endTime":1666.97,"body":"treatments that ultimately have"},{"speaker":"Stacy Lindborg","startTime":1662.83,"endTime":1666.97,"body":"not been able to work in a cold"},{"speaker":"Stacy Lindborg","startTime":1666.97,"endTime":1671.41,"body":"tumor micro environment, we are"},{"speaker":"Stacy Lindborg","startTime":1666.97,"endTime":1671.41,"body":"able to convert to hot tumor"},{"speaker":"Stacy Lindborg","startTime":1671.41,"endTime":1674.11,"body":"micro environment. What things"},{"speaker":"Stacy Lindborg","startTime":1671.41,"endTime":1674.11,"body":"might we learn, and how could"},{"speaker":"Stacy Lindborg","startTime":1674.11,"endTime":1677.995,"body":"that actually manifest in a way"},{"speaker":"Stacy Lindborg","startTime":1674.11,"endTime":1677.995,"body":"that really benefits patients?"},{"speaker":"John Simboli","startTime":1678.715,"endTime":1681.175,"body":"When people hear"},{"speaker":"John Simboli","startTime":1678.715,"endTime":1681.175,"body":"the Immunon story. What do they"},{"speaker":"John Simboli","startTime":1681.175,"endTime":1683.395,"body":"get right? What do they get"},{"speaker":"John Simboli","startTime":1681.175,"endTime":1683.395,"body":"wrong? And how do you help them"},{"speaker":"John Simboli","startTime":1683.395,"endTime":1685.135,"body":"to better understand the story?"},{"speaker":"Stacy Lindborg","startTime":1685.66,"endTime":1689.62,"body":"What people will"},{"speaker":"Stacy Lindborg","startTime":1685.66,"endTime":1689.62,"body":"often default to, they'll know"},{"speaker":"Stacy Lindborg","startTime":1689.68,"endTime":1693.76,"body":"an approach to an immunotherapy,"},{"speaker":"Stacy Lindborg","startTime":1689.68,"endTime":1693.76,"body":"and maybe don't distinguish that"},{"speaker":"Stacy Lindborg","startTime":1693.76,"endTime":1697.36,"body":"there are lots of ways that we"},{"speaker":"Stacy Lindborg","startTime":1693.76,"endTime":1697.36,"body":"can innovate and we can actually"},{"speaker":"Stacy Lindborg","startTime":1697.36,"endTime":1701.74,"body":"create immunotherapy. So they"},{"speaker":"Stacy Lindborg","startTime":1697.36,"endTime":1701.74,"body":"may assume that we have a viral"},{"speaker":"Stacy Lindborg","startTime":1701.74,"endTime":1705.34,"body":"vector or a virus that we're"},{"speaker":"Stacy Lindborg","startTime":1701.74,"endTime":1705.34,"body":"using to deliver our product."},{"speaker":"Stacy Lindborg","startTime":1705.7,"endTime":1709.3,"body":"They may assume that we're"},{"speaker":"Stacy Lindborg","startTime":1705.7,"endTime":1709.3,"body":"actually administering"},{"speaker":"Stacy Lindborg","startTime":1709.3,"endTime":1714.265,"body":"recombinant IL-2, or any other"},{"speaker":"Stacy Lindborg","startTime":1709.3,"endTime":1714.265,"body":"ways that you could bring"},{"speaker":"Stacy Lindborg","startTime":1714.265,"endTime":1717.805,"body":"forward a novel therapy. And I"},{"speaker":"Stacy Lindborg","startTime":1714.265,"endTime":1717.805,"body":"think you know it's important,"},{"speaker":"Stacy Lindborg","startTime":1717.805,"endTime":1722.845,"body":"and we intentionally designed a"},{"speaker":"Stacy Lindborg","startTime":1717.805,"endTime":1722.845,"body":"non-viral DNA platform. It's"},{"speaker":"Stacy Lindborg","startTime":1722.845,"endTime":1727.405,"body":"actually hitting the two main"},{"speaker":"Stacy Lindborg","startTime":1722.845,"endTime":1727.405,"body":"arms of the immune system,"},{"speaker":"Stacy Lindborg","startTime":1727.405,"endTime":1731.95,"body":"adaptive and innate immunity."},{"speaker":"Stacy Lindborg","startTime":1727.405,"endTime":1731.95,"body":"And even for some of our"},{"speaker":"Stacy Lindborg","startTime":1731.95,"endTime":1735.73,"body":"clinicians, when we're having"},{"speaker":"Stacy Lindborg","startTime":1731.95,"endTime":1735.73,"body":"conversations, you know, and"},{"speaker":"Stacy Lindborg","startTime":1735.73,"endTime":1738.97,"body":"we're talking about critical"},{"speaker":"Stacy Lindborg","startTime":1735.73,"endTime":1738.97,"body":"points to make, they'll"},{"speaker":"Stacy Lindborg","startTime":1738.97,"endTime":1741.85,"body":"emphasize how critical it is"},{"speaker":"Stacy Lindborg","startTime":1738.97,"endTime":1741.85,"body":"that, look, we're not just"},{"speaker":"Stacy Lindborg","startTime":1741.85,"endTime":1746.95,"body":"delivering a cytokine or"},{"speaker":"Stacy Lindborg","startTime":1741.85,"endTime":1746.95,"body":"protein. We're really activating"},{"speaker":"Stacy Lindborg","startTime":1747.37,"endTime":1750.61,"body":"both arms of the immune system."},{"speaker":"Stacy Lindborg","startTime":1747.37,"endTime":1750.61,"body":"And when you think about the"},{"speaker":"Stacy Lindborg","startTime":1750.61,"endTime":1754.57,"body":"distinct advantages, you know,"},{"speaker":"Stacy Lindborg","startTime":1750.61,"endTime":1754.57,"body":"from a safety standpoint, that's"},{"speaker":"Stacy Lindborg","startTime":1754.57,"endTime":1757.255,"body":"obviously a critical part of the"},{"speaker":"Stacy Lindborg","startTime":1754.57,"endTime":1757.255,"body":"delivery, of how we're"},{"speaker":"Stacy Lindborg","startTime":1757.255,"endTime":1761.515,"body":"delivering our product, the"},{"speaker":"Stacy Lindborg","startTime":1757.255,"endTime":1761.515,"body":"stability, the scalability that"},{"speaker":"Stacy Lindborg","startTime":1761.515,"endTime":1765.355,"body":"we can actually go beyond. There"},{"speaker":"Stacy Lindborg","startTime":1761.515,"endTime":1765.355,"body":"are many solid tumors that we've"},{"speaker":"Stacy Lindborg","startTime":1765.355,"endTime":1769.195,"body":"studied pre-clinically that we"},{"speaker":"Stacy Lindborg","startTime":1765.355,"endTime":1769.195,"body":"know will be rapid growth for"},{"speaker":"Stacy Lindborg","startTime":1769.195,"endTime":1773.095,"body":"our company and added value we"},{"speaker":"Stacy Lindborg","startTime":1769.195,"endTime":1773.095,"body":"can bring to patients. You know,"},{"speaker":"Stacy Lindborg","startTime":1773.095,"endTime":1777.055,"body":"really, it becomes about the"},{"speaker":"Stacy Lindborg","startTime":1773.095,"endTime":1777.055,"body":"uniqueness of this product and"},{"speaker":"Stacy Lindborg","startTime":1777.1,"endTime":1778.24,"body":"how we can grow."},{"speaker":"John Simboli","startTime":1778.0,"endTime":1780.82,"body":"Can you speak with"},{"speaker":"John Simboli","startTime":1778.0,"endTime":1780.82,"body":"me about your phase 3 trial"},{"speaker":"John Simboli","startTime":1780.82,"endTime":1781.42,"body":"plans?"},{"speaker":"Stacy Lindborg","startTime":1781.54,"endTime":1784.12,"body":"We have a novel"},{"speaker":"Stacy Lindborg","startTime":1781.54,"endTime":1784.12,"body":"design, but one that's really"},{"speaker":"Stacy Lindborg","startTime":1784.12,"endTime":1789.22,"body":"predicated in the FDA, that will"},{"speaker":"Stacy Lindborg","startTime":1784.12,"endTime":1789.22,"body":"allow us to move very quickly if"},{"speaker":"Stacy Lindborg","startTime":1789.22,"endTime":1795.04,"body":"we see an effect in women that"},{"speaker":"Stacy Lindborg","startTime":1789.22,"endTime":1795.04,"body":"are HRD-positive, meaning they"},{"speaker":"Stacy Lindborg","startTime":1795.04,"endTime":1799.0,"body":"have mutations that suggest,"},{"speaker":"Stacy Lindborg","startTime":1795.04,"endTime":1799.0,"body":"based on our data, that they"},{"speaker":"Stacy Lindborg","startTime":1799.0,"endTime":1803.98,"body":"would respond quickly. So we'll"},{"speaker":"Stacy Lindborg","startTime":1799.0,"endTime":1803.98,"body":"be able to do interim analyses."},{"speaker":"Stacy Lindborg","startTime":1804.025,"endTime":1808.525,"body":"If we see an effect, we'll be"},{"speaker":"Stacy Lindborg","startTime":1804.025,"endTime":1808.525,"body":"able to get the BLA, so the"},{"speaker":"Stacy Lindborg","startTime":1808.525,"endTime":1814.045,"body":"biologic license application, to"},{"speaker":"Stacy Lindborg","startTime":1808.525,"endTime":1814.045,"body":"the FDA quickly for review and"},{"speaker":"Stacy Lindborg","startTime":1814.045,"endTime":1817.765,"body":"approval, full approval in that"},{"speaker":"Stacy Lindborg","startTime":1814.045,"endTime":1817.765,"body":"subgroup, but it would match the"},{"speaker":"Stacy Lindborg","startTime":1817.765,"endTime":1821.725,"body":"urgency that I think the"},{"speaker":"Stacy Lindborg","startTime":1817.765,"endTime":1821.725,"body":"population demands while we"},{"speaker":"Stacy Lindborg","startTime":1821.725,"endTime":1827.005,"body":"study this broader, all-comers"},{"speaker":"Stacy Lindborg","startTime":1821.725,"endTime":1827.005,"body":"population. So 2 in the"},{"speaker":"Stacy Lindborg","startTime":1827.05,"endTime":1831.85,"body":"protocol, and really even the"},{"speaker":"Stacy Lindborg","startTime":1827.05,"endTime":1831.85,"body":"ongoing phase 2 study, it is"},{"speaker":"Stacy Lindborg","startTime":1831.85,"endTime":1836.05,"body":"amazing how consistent every"},{"speaker":"Stacy Lindborg","startTime":1831.85,"endTime":1836.05,"body":"single endpoint and subgroup"},{"speaker":"Stacy Lindborg","startTime":1836.05,"endTime":1839.89,"body":"points to an Immunon treatment"},{"speaker":"Stacy Lindborg","startTime":1836.05,"endTime":1839.89,"body":"effect over the standard of"},{"speaker":"Stacy Lindborg","startTime":1839.89,"endTime":1844.63,"body":"care. And that consistency gives"},{"speaker":"Stacy Lindborg","startTime":1839.89,"endTime":1844.63,"body":"us just such confidence as we go"},{"speaker":"Stacy Lindborg","startTime":1844.63,"endTime":1848.05,"body":"into this phase 3 trial. This"},{"speaker":"Stacy Lindborg","startTime":1844.63,"endTime":1848.05,"body":"very well powered 500 patient"},{"speaker":"Stacy Lindborg","startTime":1848.53,"endTime":1853.135,"body":"trial that allows for early"},{"speaker":"Stacy Lindborg","startTime":1848.53,"endTime":1853.135,"body":"action, for success and access"},{"speaker":"Stacy Lindborg","startTime":1853.135,"endTime":1854.515,"body":"to the public that needs it.l"},{"speaker":"John Simboli","startTime":1855.055,"endTime":1857.215,"body":"Stacy, thanks for"},{"speaker":"John Simboli","startTime":1855.055,"endTime":1857.215,"body":"speaking with me today."},{"speaker":"Stacy Lindborg","startTime":1857.4,"endTime":1859.68,"body":"Thank you. It"},{"speaker":"Stacy Lindborg","startTime":1857.4,"endTime":1859.68,"body":"has truly been a highlight of my"},{"speaker":"Stacy Lindborg","startTime":1859.68,"endTime":1860.16,"body":"day."}]}