{"version":"1.0.0","segments":[{"speaker":"Shaun Bagai","startTime":5.7,"endTime":8.13,"body":"I love learning,"},{"speaker":"Shaun Bagai","startTime":5.7,"endTime":8.13,"body":"changing, pivoting, doing."},{"speaker":"John Simboli","startTime":37.565,"endTime":43.415,"body":"Sean, what led to"},{"speaker":"John Simboli","startTime":37.565,"endTime":43.415,"body":"your role as CEO at RenovoRx?"},{"speaker":"Shaun Bagai","startTime":44.44,"endTime":47.26,"body":"I've been in the"},{"speaker":"Shaun Bagai","startTime":44.44,"endTime":47.26,"body":"medical technology space my"},{"speaker":"Shaun Bagai","startTime":47.26,"endTime":50.41,"body":"whole career, and I was med"},{"speaker":"Shaun Bagai","startTime":47.26,"endTime":50.41,"body":"school bound initially. And I"},{"speaker":"Shaun Bagai","startTime":50.41,"endTime":53.14,"body":"turned what was a one-year"},{"speaker":"Shaun Bagai","startTime":50.41,"endTime":53.14,"body":"internship between college and"},{"speaker":"Shaun Bagai","startTime":53.14,"endTime":55.96,"body":"what would have been med school"},{"speaker":"Shaun Bagai","startTime":53.14,"endTime":55.96,"body":"into a career that has gotten me"},{"speaker":"Shaun Bagai","startTime":55.96,"endTime":60.1,"body":"to be able to help build new"},{"speaker":"Shaun Bagai","startTime":55.96,"endTime":60.1,"body":"disruptive therapies over the"},{"speaker":"Shaun Bagai","startTime":60.1,"endTime":63.88,"body":"last few decades, It really was"},{"speaker":"Shaun Bagai","startTime":60.1,"endTime":63.88,"body":"a passion for medicine"},{"speaker":"Shaun Bagai","startTime":63.88,"endTime":66.13,"body":"initially, and then being"},{"speaker":"Shaun Bagai","startTime":63.88,"endTime":66.13,"body":"convinced not to go to med"},{"speaker":"Shaun Bagai","startTime":66.13,"endTime":69.025,"body":"school once I get in to build"},{"speaker":"Shaun Bagai","startTime":66.13,"endTime":69.025,"body":"companies that would someday"},{"speaker":"Shaun Bagai","startTime":69.025,"endTime":72.115,"body":"really help patients at a"},{"speaker":"Shaun Bagai","startTime":69.025,"endTime":72.115,"body":"broader level than one could as"},{"speaker":"Shaun Bagai","startTime":72.115,"endTime":75.295,"body":"a single physician. So with"},{"speaker":"Shaun Bagai","startTime":72.115,"endTime":75.295,"body":"that, through my career, I built"},{"speaker":"Shaun Bagai","startTime":75.295,"endTime":78.115,"body":"up my career to hopefully"},{"speaker":"Shaun Bagai","startTime":75.295,"endTime":78.115,"body":"disrupt medical technology to"},{"speaker":"Shaun Bagai","startTime":78.115,"endTime":81.535,"body":"make those changes, and had the"},{"speaker":"Shaun Bagai","startTime":78.115,"endTime":81.535,"body":"opportunity to take over as CEO"},{"speaker":"Shaun Bagai","startTime":81.535,"endTime":84.625,"body":"of RenovoRx about 11 and a half"},{"speaker":"Shaun Bagai","startTime":81.535,"endTime":84.625,"body":"years ago to really make a big"},{"speaker":"Shaun Bagai","startTime":84.625,"endTime":86.845,"body":"impact in this case on on cancer"},{"speaker":"Shaun Bagai","startTime":84.625,"endTime":86.845,"body":"care."},{"speaker":"John Simboli","startTime":87.11,"endTime":89.87,"body":"When you say to"},{"speaker":"John Simboli","startTime":87.11,"endTime":89.87,"body":"your loved ones, your family,"},{"speaker":"John Simboli","startTime":89.87,"endTime":92.33,"body":"others, and you say, \"I'm not"},{"speaker":"John Simboli","startTime":89.87,"endTime":92.33,"body":"going to go down this"},{"speaker":"John Simboli","startTime":92.33,"endTime":95.15,"body":"traditional path,\" you may feel"},{"speaker":"John Simboli","startTime":92.33,"endTime":95.15,"body":"good about it. How do you deal"},{"speaker":"John Simboli","startTime":95.15,"endTime":97.16,"body":"with how other people feel about"},{"speaker":"John Simboli","startTime":95.15,"endTime":97.16,"body":"stuff like that?"},{"speaker":"Shaun Bagai","startTime":97.78,"endTime":99.22,"body":"You know, it's a"},{"speaker":"Shaun Bagai","startTime":97.78,"endTime":99.22,"body":"very interesting question"},{"speaker":"Shaun Bagai","startTime":99.22,"endTime":103.03,"body":"because being the son of Indian"},{"speaker":"Shaun Bagai","startTime":99.22,"endTime":103.03,"body":"parents, you can imagine what"},{"speaker":"Shaun Bagai","startTime":103.03,"endTime":106.48,"body":"happens when you go through the"},{"speaker":"Shaun Bagai","startTime":103.03,"endTime":106.48,"body":"painstaking process of applying"},{"speaker":"Shaun Bagai","startTime":106.48,"endTime":109.24,"body":"to med school, taking the MCATs"},{"speaker":"Shaun Bagai","startTime":106.48,"endTime":109.24,"body":"a couple times, interviews,"},{"speaker":"Shaun Bagai","startTime":109.24,"endTime":113.5,"body":"flying around, and then the very"},{"speaker":"Shaun Bagai","startTime":109.24,"endTime":113.5,"body":"small percentage of people on"},{"speaker":"Shaun Bagai","startTime":113.5,"endTime":115.93,"body":"actually getting into medical"},{"speaker":"Shaun Bagai","startTime":113.5,"endTime":115.93,"body":"school and then declining it."},{"speaker":"Shaun Bagai","startTime":115.93,"endTime":119.23,"body":"You can imagine the backlash"},{"speaker":"Shaun Bagai","startTime":115.93,"endTime":119.23,"body":"from family members, especially"},{"speaker":"Shaun Bagai","startTime":119.23,"endTime":123.895,"body":"with a lot of cardiology in my"},{"speaker":"Shaun Bagai","startTime":119.23,"endTime":123.895,"body":"family, and so my parents were"},{"speaker":"Shaun Bagai","startTime":123.895,"endTime":128.575,"body":"not happy. My cousin, who is an"},{"speaker":"Shaun Bagai","startTime":123.895,"endTime":128.575,"body":"esteemed electrophysiologist and"},{"speaker":"Shaun Bagai","startTime":128.575,"endTime":131.935,"body":"cardiologist, wouldn't talk to"},{"speaker":"Shaun Bagai","startTime":128.575,"endTime":131.935,"body":"me for three years. My aunt, who"},{"speaker":"Shaun Bagai","startTime":131.935,"endTime":134.275,"body":"is probably one of the most"},{"speaker":"Shaun Bagai","startTime":131.935,"endTime":134.275,"body":"world-renowned cardiac"},{"speaker":"Shaun Bagai","startTime":134.275,"endTime":137.815,"body":"pathologists, had berated me. I"},{"speaker":"Shaun Bagai","startTime":134.275,"endTime":137.815,"body":"think for the subsequent six or"},{"speaker":"Shaun Bagai","startTime":137.815,"endTime":141.205,"body":"seven years to go back to med"},{"speaker":"Shaun Bagai","startTime":137.815,"endTime":141.205,"body":"school or reapply and get back"},{"speaker":"Shaun Bagai","startTime":141.205,"endTime":144.085,"body":"in and go, and it wasn't until"},{"speaker":"Shaun Bagai","startTime":141.205,"endTime":144.085,"body":"my late 20s when my career"},{"speaker":"Shaun Bagai","startTime":144.13,"endTime":147.22,"body":"really started to take off that"},{"speaker":"Shaun Bagai","startTime":144.13,"endTime":147.22,"body":"they all kind of stopped, and"},{"speaker":"Shaun Bagai","startTime":147.22,"endTime":149.32,"body":"since then they've been very"},{"speaker":"Shaun Bagai","startTime":147.22,"endTime":149.32,"body":"happy and proud of of what I've"},{"speaker":"Shaun Bagai","startTime":149.32,"endTime":151.75,"body":"been able to accomplish in my"},{"speaker":"Shaun Bagai","startTime":149.32,"endTime":151.75,"body":"career. And I get to do both. I"},{"speaker":"Shaun Bagai","startTime":151.75,"endTime":154.36,"body":"can do medicine and business,"},{"speaker":"Shaun Bagai","startTime":151.75,"endTime":154.36,"body":"which is really satisfying."},{"speaker":"John Simboli","startTime":155.09,"endTime":158.21,"body":"How did you summon"},{"speaker":"John Simboli","startTime":155.09,"endTime":158.21,"body":"the courage between declining"},{"speaker":"John Simboli","startTime":158.27,"endTime":161.68,"body":"medical school and becoming"},{"speaker":"John Simboli","startTime":158.27,"endTime":161.68,"body":"noted in your field so that"},{"speaker":"John Simboli","startTime":161.74,"endTime":163.66,"body":"people would take notice,"},{"speaker":"John Simboli","startTime":161.74,"endTime":163.66,"body":"including your family. How did"},{"speaker":"John Simboli","startTime":163.72,"endTime":165.61,"body":"you how did you work through"},{"speaker":"John Simboli","startTime":163.72,"endTime":165.61,"body":"that interval?"},{"speaker":"Shaun Bagai","startTime":166.0,"endTime":170.35,"body":"I think it started"},{"speaker":"Shaun Bagai","startTime":166.0,"endTime":170.35,"body":"with my dad initially. He really"},{"speaker":"Shaun Bagai","startTime":170.35,"endTime":173.08,"body":"said, \"Son, listen, you know,"},{"speaker":"Shaun Bagai","startTime":170.35,"endTime":173.08,"body":"follow your heart, follow your"},{"speaker":"Shaun Bagai","startTime":173.08,"endTime":176.62,"body":"passion, and success will come.\""},{"speaker":"Shaun Bagai","startTime":173.08,"endTime":176.62,"body":"And he knew that I was"},{"speaker":"Shaun Bagai","startTime":176.62,"endTime":179.77,"body":"passionate about medicine, and"},{"speaker":"Shaun Bagai","startTime":176.62,"endTime":179.77,"body":"before that, I would he knew I"},{"speaker":"Shaun Bagai","startTime":179.77,"endTime":182.89,"body":"was passionate about business,"},{"speaker":"Shaun Bagai","startTime":179.77,"endTime":182.89,"body":"and he said, \"Look, if if you're"},{"speaker":"Shaun Bagai","startTime":182.89,"endTime":186.79,"body":"not 100% in this, it's a long"},{"speaker":"Shaun Bagai","startTime":182.89,"endTime":186.79,"body":"road. Don't do it.\" And so he"},{"speaker":"Shaun Bagai","startTime":186.79,"endTime":191.035,"body":"kind of gave me the initial"},{"speaker":"Shaun Bagai","startTime":186.79,"endTime":191.035,"body":"spark of let me reconsider this,"},{"speaker":"Shaun Bagai","startTime":191.035,"endTime":194.545,"body":"and then the other piece is one"},{"speaker":"Shaun Bagai","startTime":191.035,"endTime":194.545,"body":"of my mentors earlier on, again,"},{"speaker":"Shaun Bagai","startTime":194.545,"endTime":198.775,"body":"the the founder, CEO, physician"},{"speaker":"Shaun Bagai","startTime":194.545,"endTime":198.775,"body":"of my first company, he gave me"},{"speaker":"Shaun Bagai","startTime":198.775,"endTime":202.945,"body":"the confidence that there is a"},{"speaker":"Shaun Bagai","startTime":198.775,"endTime":202.945,"body":"path less taken than what I call"},{"speaker":"Shaun Bagai","startTime":202.945,"endTime":205.045,"body":"the railroad tracks laid out in"},{"speaker":"Shaun Bagai","startTime":202.945,"endTime":205.045,"body":"front of me. Once you got into"},{"speaker":"Shaun Bagai","startTime":205.045,"endTime":207.925,"body":"medical school, there's a very"},{"speaker":"Shaun Bagai","startTime":205.045,"endTime":207.925,"body":"small chance of not becoming a"},{"speaker":"Shaun Bagai","startTime":207.925,"endTime":209.965,"body":"physician if that's your dream."},{"speaker":"Shaun Bagai","startTime":207.925,"endTime":209.965,"body":"That's the hardest part is"},{"speaker":"Shaun Bagai","startTime":209.965,"endTime":212.62,"body":"getting in. Once you're there,"},{"speaker":"Shaun Bagai","startTime":209.965,"endTime":212.62,"body":"it's a matter of execution, and"},{"speaker":"Shaun Bagai","startTime":212.62,"endTime":215.83,"body":"that transition is a tough part."},{"speaker":"Shaun Bagai","startTime":212.62,"endTime":215.83,"body":"And I felt like there was a"},{"speaker":"Shaun Bagai","startTime":215.83,"endTime":219.52,"body":"railroad track of you go to med"},{"speaker":"Shaun Bagai","startTime":215.83,"endTime":219.52,"body":"school, you go to residency, you"},{"speaker":"Shaun Bagai","startTime":219.52,"endTime":223.69,"body":"specialize, you know, private"},{"speaker":"Shaun Bagai","startTime":219.52,"endTime":223.69,"body":"practice or large hospitals, and"},{"speaker":"Shaun Bagai","startTime":223.69,"endTime":226.54,"body":"my success and my involvement in"},{"speaker":"Shaun Bagai","startTime":223.69,"endTime":226.54,"body":"medicine is pretty much laid"},{"speaker":"Shaun Bagai","startTime":226.54,"endTime":230.32,"body":"out. Derailing that to take the"},{"speaker":"Shaun Bagai","startTime":226.54,"endTime":230.32,"body":"unknown path of well, let me"},{"speaker":"Shaun Bagai","startTime":230.32,"endTime":233.89,"body":"become an entrepreneur and"},{"speaker":"Shaun Bagai","startTime":230.32,"endTime":233.89,"body":"hopefully build my career, and"},{"speaker":"Shaun Bagai","startTime":233.89,"endTime":237.115,"body":"failure is not an option was the"},{"speaker":"Shaun Bagai","startTime":233.89,"endTime":237.115,"body":"way I drove it. So I think it"},{"speaker":"Shaun Bagai","startTime":237.115,"endTime":239.575,"body":"sparked from those two"},{"speaker":"Shaun Bagai","startTime":237.115,"endTime":239.575,"body":"influences earlier on, and then"},{"speaker":"Shaun Bagai","startTime":239.575,"endTime":240.265,"body":"just ran with it."},{"speaker":"John Simboli","startTime":240.78,"endTime":243.63,"body":"When you make a"},{"speaker":"John Simboli","startTime":240.78,"endTime":243.63,"body":"choice like that to build a"},{"speaker":"John Simboli","startTime":243.63,"endTime":247.47,"body":"business rather than to treat a"},{"speaker":"John Simboli","startTime":243.63,"endTime":247.47,"body":"patient, there's a shift there,"},{"speaker":"John Simboli","startTime":247.47,"endTime":250.92,"body":"right? Tell me if I'm right."},{"speaker":"John Simboli","startTime":247.47,"endTime":250.92,"body":"That one of them is the hope of"},{"speaker":"John Simboli","startTime":250.92,"endTime":254.34,"body":"making a huge impact on a small"},{"speaker":"John Simboli","startTime":250.92,"endTime":254.34,"body":"number of people, the patients"},{"speaker":"John Simboli","startTime":254.34,"endTime":257.46,"body":"you're treating. The other one"},{"speaker":"John Simboli","startTime":254.34,"endTime":257.46,"body":"is potentially making a big"},{"speaker":"John Simboli","startTime":257.46,"endTime":260.85,"body":"impact on a larger number of"},{"speaker":"John Simboli","startTime":257.46,"endTime":260.85,"body":"patients. Is that an important"},{"speaker":"John Simboli","startTime":260.85,"endTime":262.98,"body":"consideration you had when you"},{"speaker":"John Simboli","startTime":260.85,"endTime":262.98,"body":"were making your choice?"},{"speaker":"Shaun Bagai","startTime":263.29,"endTime":266.17,"body":"That was 100% the"},{"speaker":"Shaun Bagai","startTime":263.29,"endTime":266.17,"body":"biggest driver. It was a matter"},{"speaker":"Shaun Bagai","startTime":266.17,"endTime":270.34,"body":"of seeing the opportunity to"},{"speaker":"Shaun Bagai","startTime":266.17,"endTime":270.34,"body":"really disrupt healthcare, and"},{"speaker":"Shaun Bagai","startTime":270.34,"endTime":274.42,"body":"I've been lucky, and hard work"},{"speaker":"Shaun Bagai","startTime":270.34,"endTime":274.42,"body":"has paid off. For every company"},{"speaker":"Shaun Bagai","startTime":274.42,"endTime":277.96,"body":"I worked for has had a major"},{"speaker":"Shaun Bagai","startTime":274.42,"endTime":277.96,"body":"impact on patients that I saw"},{"speaker":"Shaun Bagai","startTime":277.96,"endTime":282.04,"body":"firsthand, on patients that many"},{"speaker":"Shaun Bagai","startTime":277.96,"endTime":282.04,"body":"physicians I worked with,"},{"speaker":"Shaun Bagai","startTime":282.04,"endTime":285.715,"body":"they're trained or collaborated"},{"speaker":"Shaun Bagai","startTime":282.04,"endTime":285.715,"body":"with had on their patients, and"},{"speaker":"Shaun Bagai","startTime":285.715,"endTime":289.255,"body":"and then as my career grew, on"},{"speaker":"Shaun Bagai","startTime":285.715,"endTime":289.255,"body":"on many individuals who go on to"},{"speaker":"Shaun Bagai","startTime":289.255,"endTime":293.395,"body":"do similar things as a leader,"},{"speaker":"Shaun Bagai","startTime":289.255,"endTime":293.395,"body":"and really it's been a great"},{"speaker":"Shaun Bagai","startTime":293.395,"endTime":296.965,"body":"network of my career growth and"},{"speaker":"Shaun Bagai","startTime":293.395,"endTime":296.965,"body":"in terms of medical success in"},{"speaker":"Shaun Bagai","startTime":296.965,"endTime":299.065,"body":"my previous companies and this"},{"speaker":"Shaun Bagai","startTime":296.965,"endTime":299.065,"body":"one as well."},{"speaker":"John Simboli","startTime":299.42,"endTime":302.0,"body":"Can you recall?"},{"speaker":"John Simboli","startTime":299.42,"endTime":302.0,"body":"When you were a young person,"},{"speaker":"John Simboli","startTime":302.0,"endTime":305.18,"body":"and and your self image and how"},{"speaker":"John Simboli","startTime":302.0,"endTime":305.18,"body":"you imagined your life might"},{"speaker":"John Simboli","startTime":305.18,"endTime":308.12,"body":"turn out to be? Some of us think"},{"speaker":"John Simboli","startTime":305.18,"endTime":308.12,"body":"about those things at that early"},{"speaker":"John Simboli","startTime":308.12,"endTime":308.54,"body":"age."},{"speaker":"Shaun Bagai","startTime":308.91,"endTime":312.63,"body":"It's funny. I was"},{"speaker":"Shaun Bagai","startTime":308.91,"endTime":312.63,"body":"very business minded, as my my"},{"speaker":"Shaun Bagai","startTime":312.75,"endTime":316.65,"body":"father was before he retired,"},{"speaker":"Shaun Bagai","startTime":312.75,"endTime":316.65,"body":"and I liked kind of thinking"},{"speaker":"Shaun Bagai","startTime":316.71,"endTime":319.86,"body":"about building businesses and"},{"speaker":"Shaun Bagai","startTime":316.71,"endTime":319.86,"body":"selling things at a young age"},{"speaker":"Shaun Bagai","startTime":320.61,"endTime":323.84,"body":"when I was a child, and I don't"},{"speaker":"Shaun Bagai","startTime":320.61,"endTime":323.84,"body":"remember I was eight or nine or"},{"speaker":"Shaun Bagai","startTime":323.99,"endTime":328.61,"body":"10, I used to buy things from"},{"speaker":"Shaun Bagai","startTime":323.99,"endTime":328.61,"body":"India on family trips and then"},{"speaker":"Shaun Bagai","startTime":328.73,"endTime":331.46,"body":"sell them out of my bedroom. And"},{"speaker":"Shaun Bagai","startTime":328.73,"endTime":331.46,"body":"I had a little sign that said"},{"speaker":"Shaun Bagai","startTime":331.88,"endTime":335.18,"body":"Sean's Neat Boutique, and I got"},{"speaker":"Shaun Bagai","startTime":331.88,"endTime":335.18,"body":"made fun of it a lot as a kid."},{"speaker":"Shaun Bagai","startTime":335.87,"endTime":339.17,"body":"But I think there was inherent"},{"speaker":"Shaun Bagai","startTime":335.87,"endTime":339.17,"body":"business mind inside of me that"},{"speaker":"Shaun Bagai","startTime":339.44,"endTime":342.67,"body":"had always been there. And my"},{"speaker":"Shaun Bagai","startTime":339.44,"endTime":342.67,"body":"dad was also an entrepreneur and"},{"speaker":"Shaun Bagai","startTime":342.7,"endTime":345.16,"body":"and different levels, and and I"},{"speaker":"Shaun Bagai","startTime":342.7,"endTime":345.16,"body":"think maybe that kind of came"},{"speaker":"Shaun Bagai","startTime":345.22,"endTime":349.15,"body":"from him to a degree, and also I"},{"speaker":"Shaun Bagai","startTime":345.22,"endTime":349.15,"body":"had a paper route when I was I"},{"speaker":"Shaun Bagai","startTime":349.21,"endTime":352.57,"body":"think 11 years old, and I"},{"speaker":"Shaun Bagai","startTime":349.21,"endTime":352.57,"body":"delivered newspapers, got up"},{"speaker":"Shaun Bagai","startTime":352.6,"endTime":354.91,"body":"every morning at 4o'clock,"},{"speaker":"Shaun Bagai","startTime":352.6,"endTime":354.91,"body":"folded papers, rode my bike"},{"speaker":"Shaun Bagai","startTime":355.06,"endTime":357.82,"body":"around you know the crack of"},{"speaker":"Shaun Bagai","startTime":355.06,"endTime":357.82,"body":"dawn through the rainstorms, and"},{"speaker":"Shaun Bagai","startTime":358.27,"endTime":360.75,"body":"and so always had this kind of"},{"speaker":"Shaun Bagai","startTime":358.27,"endTime":360.75,"body":"business minded you know sense"},{"speaker":"Shaun Bagai","startTime":360.84,"endTime":362.19,"body":"of hard work from a very young"},{"speaker":"Shaun Bagai","startTime":360.84,"endTime":362.19,"body":"age."},{"speaker":"John Simboli","startTime":362.96,"endTime":365.9,"body":"If I were to ask,"},{"speaker":"John Simboli","startTime":362.96,"endTime":365.9,"body":"you know, four, five, ten people"},{"speaker":"John Simboli","startTime":365.9,"endTime":369.56,"body":"in your current team, what's"},{"speaker":"John Simboli","startTime":365.9,"endTime":369.56,"body":"Sean's management style? What do"},{"speaker":"John Simboli","startTime":369.56,"endTime":371.87,"body":"you think management approach?"},{"speaker":"John Simboli","startTime":369.56,"endTime":371.87,"body":"What do you think they might"},{"speaker":"John Simboli","startTime":371.87,"endTime":372.29,"body":"say?"},{"speaker":"Shaun Bagai","startTime":373.68,"endTime":377.16,"body":"I would say part of"},{"speaker":"Shaun Bagai","startTime":373.68,"endTime":377.16,"body":"it's passion for what I do and"},{"speaker":"Shaun Bagai","startTime":377.16,"endTime":382.29,"body":"and demonstrating everything it"},{"speaker":"Shaun Bagai","startTime":377.16,"endTime":382.29,"body":"takes and anything it takes to"},{"speaker":"Shaun Bagai","startTime":382.29,"endTime":386.73,"body":"get the job done and to make"},{"speaker":"Shaun Bagai","startTime":382.29,"endTime":386.73,"body":"things happen, as disruptive"},{"speaker":"Shaun Bagai","startTime":386.73,"endTime":389.37,"body":"startup companies or smaller"},{"speaker":"Shaun Bagai","startTime":386.73,"endTime":389.37,"body":"companies aren't easy because"},{"speaker":"Shaun Bagai","startTime":389.37,"endTime":391.8,"body":"the road is not laid out for"},{"speaker":"Shaun Bagai","startTime":389.37,"endTime":391.8,"body":"you. It's not just a matter of"},{"speaker":"Shaun Bagai","startTime":391.8,"endTime":394.98,"body":"increasing or growing a certain"},{"speaker":"Shaun Bagai","startTime":391.8,"endTime":394.98,"body":"aspect. It's really learning,"},{"speaker":"Shaun Bagai","startTime":395.025,"endTime":398.715,"body":"discovering, pivoting, taking on"},{"speaker":"Shaun Bagai","startTime":395.025,"endTime":398.715,"body":"the stress. So it's"},{"speaker":"Shaun Bagai","startTime":398.715,"endTime":402.855,"body":"demonstrating the pushing"},{"speaker":"Shaun Bagai","startTime":398.715,"endTime":402.855,"body":"through everything to get things"},{"speaker":"Shaun Bagai","startTime":402.855,"endTime":406.125,"body":"done that you need to, and I"},{"speaker":"Shaun Bagai","startTime":402.855,"endTime":406.125,"body":"think the other piece is"},{"speaker":"Shaun Bagai","startTime":406.125,"endTime":409.065,"body":"remaining calm. It's very"},{"speaker":"Shaun Bagai","startTime":406.125,"endTime":409.065,"body":"important in this environment"},{"speaker":"Shaun Bagai","startTime":409.065,"endTime":413.655,"body":"to, no matter what's going on,"},{"speaker":"Shaun Bagai","startTime":409.065,"endTime":413.655,"body":"to develop and give the team a"},{"speaker":"Shaun Bagai","startTime":413.655,"endTime":419.7,"body":"sense of calmness, of success,"},{"speaker":"Shaun Bagai","startTime":413.655,"endTime":419.7,"body":"of handling situations. There's"},{"speaker":"Shaun Bagai","startTime":419.7,"endTime":423.78,"body":"nothing that's insurmountable,"},{"speaker":"Shaun Bagai","startTime":419.7,"endTime":423.78,"body":"and not being the opposite of"},{"speaker":"Shaun Bagai","startTime":423.78,"endTime":428.22,"body":"that, not looking stressed or"},{"speaker":"Shaun Bagai","startTime":423.78,"endTime":428.22,"body":"distraught or confused, which"},{"speaker":"Shaun Bagai","startTime":428.22,"endTime":431.01,"body":"I've seen a lot of leaders"},{"speaker":"Shaun Bagai","startTime":428.22,"endTime":431.01,"body":"sometimes they can't internalize"},{"speaker":"Shaun Bagai","startTime":431.01,"endTime":435.45,"body":"the stresses that they face and"},{"speaker":"Shaun Bagai","startTime":431.01,"endTime":435.45,"body":"they externalize what they're"},{"speaker":"Shaun Bagai","startTime":435.45,"endTime":439.02,"body":"feeling, and it really disrupts"},{"speaker":"Shaun Bagai","startTime":435.45,"endTime":439.02,"body":"the team in terms of them being"},{"speaker":"Shaun Bagai","startTime":439.02,"endTime":441.855,"body":"able to function and feel"},{"speaker":"Shaun Bagai","startTime":439.02,"endTime":441.855,"body":"confident that the ship's going"},{"speaker":"Shaun Bagai","startTime":441.855,"endTime":445.125,"body":"to keep going and we're going to"},{"speaker":"Shaun Bagai","startTime":441.855,"endTime":445.125,"body":"be successful. And being in this"},{"speaker":"Shaun Bagai","startTime":445.125,"endTime":447.615,"body":"company for 11 and a half years,"},{"speaker":"Shaun Bagai","startTime":445.125,"endTime":447.615,"body":"we've had a lot of situations"},{"speaker":"Shaun Bagai","startTime":447.615,"endTime":450.465,"body":"where, you know, we're running"},{"speaker":"Shaun Bagai","startTime":447.615,"endTime":450.465,"body":"out of money, or there's a"},{"speaker":"Shaun Bagai","startTime":450.465,"endTime":453.645,"body":"slowdown in the clinical trial,"},{"speaker":"Shaun Bagai","startTime":450.465,"endTime":453.645,"body":"or you know, many different"},{"speaker":"Shaun Bagai","startTime":453.645,"endTime":456.885,"body":"things that happen in early"},{"speaker":"Shaun Bagai","startTime":453.645,"endTime":456.885,"body":"stage companies. And having the"},{"speaker":"Shaun Bagai","startTime":456.885,"endTime":459.885,"body":"team not feel the stresses that"},{"speaker":"Shaun Bagai","startTime":456.885,"endTime":459.885,"body":"have to deal with, and confident"},{"speaker":"Shaun Bagai","startTime":459.885,"endTime":462.225,"body":"that whatever it is, I'll find a"},{"speaker":"Shaun Bagai","startTime":459.885,"endTime":462.225,"body":"way around it, and we will"},{"speaker":"Shaun Bagai","startTime":462.225,"endTime":464.055,"body":"together find a way around it."},{"speaker":"Shaun Bagai","startTime":462.225,"endTime":464.055,"body":"is really important."},{"speaker":"John Simboli","startTime":464.69,"endTime":466.61,"body":"When you met the"},{"speaker":"John Simboli","startTime":464.69,"endTime":466.61,"body":"person you described as your"},{"speaker":"John Simboli","startTime":466.61,"endTime":470.36,"body":"mentor at the first company that"},{"speaker":"John Simboli","startTime":466.61,"endTime":470.36,"body":"you worked at, do you think it"},{"speaker":"John Simboli","startTime":470.36,"endTime":476.39,"body":"was the case that he said, \"Oh,"},{"speaker":"John Simboli","startTime":470.36,"endTime":476.39,"body":"I see a kindred spirit. There's"},{"speaker":"John Simboli","startTime":476.39,"endTime":479.69,"body":"some qualities in Sean that I"},{"speaker":"John Simboli","startTime":476.39,"endTime":479.69,"body":"recognize in myself. Therefore,"},{"speaker":"John Simboli","startTime":479.69,"endTime":482.51,"body":"I'm going to advise him this"},{"speaker":"John Simboli","startTime":479.69,"endTime":482.51,"body":"way,\" or was it more like \"I"},{"speaker":"John Simboli","startTime":482.51,"endTime":485.51,"body":"tell everybody this because I"},{"speaker":"John Simboli","startTime":482.51,"endTime":485.51,"body":"believe in this for myself?\""},{"speaker":"Shaun Bagai","startTime":485.48,"endTime":487.34,"body":"You know, I haven't"},{"speaker":"Shaun Bagai","startTime":485.48,"endTime":487.34,"body":"been asked that before. It's a"},{"speaker":"Shaun Bagai","startTime":487.34,"endTime":490.67,"body":"funny story because I kept"},{"speaker":"Shaun Bagai","startTime":487.34,"endTime":490.67,"body":"asking him. Now, this was when I"},{"speaker":"Shaun Bagai","startTime":490.67,"endTime":493.13,"body":"was I had worked with him before"},{"speaker":"Shaun Bagai","startTime":490.67,"endTime":493.13,"body":"when I was 18-19, in an"},{"speaker":"Shaun Bagai","startTime":493.13,"endTime":496.97,"body":"internship at Stanford, met the"},{"speaker":"Shaun Bagai","startTime":493.13,"endTime":496.97,"body":"company through their animal"},{"speaker":"Shaun Bagai","startTime":496.97,"endTime":500.27,"body":"facility, and then did a one"},{"speaker":"Shaun Bagai","startTime":496.97,"endTime":500.27,"body":"year internship after college."},{"speaker":"Shaun Bagai","startTime":500.27,"endTime":503.36,"body":"So, the age of 22, the first"},{"speaker":"Shaun Bagai","startTime":500.27,"endTime":503.36,"body":"several months, I kept going to"},{"speaker":"Shaun Bagai","startTime":503.36,"endTime":506.15,"body":"his office and hounding him,"},{"speaker":"Shaun Bagai","startTime":503.36,"endTime":506.15,"body":"asking, \"You're a doctor. Why"},{"speaker":"Shaun Bagai","startTime":506.15,"endTime":508.775,"body":"don't you practice? What are you"},{"speaker":"Shaun Bagai","startTime":506.15,"endTime":508.775,"body":"doing here in an office?\" And he"},{"speaker":"Shaun Bagai","startTime":508.775,"endTime":510.785,"body":"would never give me a straight"},{"speaker":"Shaun Bagai","startTime":508.775,"endTime":510.785,"body":"answer. He would kind of blow it"},{"speaker":"Shaun Bagai","startTime":510.785,"endTime":514.145,"body":"off. And after maybe the 50th"},{"speaker":"Shaun Bagai","startTime":510.785,"endTime":514.145,"body":"time I asked him, he said,"},{"speaker":"Shaun Bagai","startTime":514.145,"endTime":516.305,"body":"\"Sean, come here.\" And this is"},{"speaker":"Shaun Bagai","startTime":514.145,"endTime":516.305,"body":"probably a few months into the"},{"speaker":"Shaun Bagai","startTime":516.305,"endTime":519.905,"body":"job. He closed the door and"},{"speaker":"Shaun Bagai","startTime":516.305,"endTime":519.905,"body":"said, \"Here's the deal. I love"},{"speaker":"Shaun Bagai","startTime":519.905,"endTime":523.175,"body":"medicine,\" and he's very"},{"speaker":"Shaun Bagai","startTime":519.905,"endTime":523.175,"body":"inventive. He's gone on to start"},{"speaker":"Shaun Bagai","startTime":523.175,"endTime":525.845,"body":"and build and sell many"},{"speaker":"Shaun Bagai","startTime":523.175,"endTime":525.845,"body":"companies that have made big"},{"speaker":"Shaun Bagai","startTime":525.845,"endTime":529.565,"body":"impact to medicine since then."},{"speaker":"Shaun Bagai","startTime":525.845,"endTime":529.565,"body":"And he said, \"I want to build"},{"speaker":"Shaun Bagai","startTime":529.565,"endTime":533.09,"body":"companies to help patients.\" and"},{"speaker":"Shaun Bagai","startTime":529.565,"endTime":533.09,"body":"he said, \"I see that in you.\""},{"speaker":"Shaun Bagai","startTime":533.09,"endTime":537.56,"body":"And he said, \"You work very"},{"speaker":"Shaun Bagai","startTime":533.09,"endTime":537.56,"body":"hard, and you find any way and"},{"speaker":"Shaun Bagai","startTime":537.56,"endTime":541.19,"body":"every way to get something done."},{"speaker":"Shaun Bagai","startTime":537.56,"endTime":541.19,"body":"And I think those skill sets put"},{"speaker":"Shaun Bagai","startTime":541.19,"endTime":544.88,"body":"together, and also on the other"},{"speaker":"Shaun Bagai","startTime":541.19,"endTime":544.88,"body":"side of it, once you specialize"},{"speaker":"Shaun Bagai","startTime":544.88,"endTime":546.62,"body":"in one area of medicine, you're"},{"speaker":"Shaun Bagai","startTime":544.88,"endTime":546.62,"body":"kind of stuck with that"},{"speaker":"Shaun Bagai","startTime":546.62,"endTime":550.07,"body":"specialty, and it could get"},{"speaker":"Shaun Bagai","startTime":546.62,"endTime":550.07,"body":"mundane for you. And I can see"},{"speaker":"Shaun Bagai","startTime":550.07,"endTime":552.17,"body":"your passion for what you do,"},{"speaker":"Shaun Bagai","startTime":550.07,"endTime":552.17,"body":"and I can see your passion for"},{"speaker":"Shaun Bagai","startTime":552.17,"endTime":555.215,"body":"medicine, and you put all those"},{"speaker":"Shaun Bagai","startTime":552.17,"endTime":555.215,"body":"things together, and I think you"},{"speaker":"Shaun Bagai","startTime":555.215,"endTime":558.395,"body":"could basically do what I do and"},{"speaker":"Shaun Bagai","startTime":555.215,"endTime":558.395,"body":"and build a career and and"},{"speaker":"Shaun Bagai","startTime":558.395,"endTime":561.815,"body":"disrupt technologies,\" like he"},{"speaker":"Shaun Bagai","startTime":558.395,"endTime":561.815,"body":"was starting to do back then,"},{"speaker":"Shaun Bagai","startTime":561.815,"endTime":566.135,"body":"now he's done many times since."},{"speaker":"Shaun Bagai","startTime":561.815,"endTime":566.135,"body":"So, 100% I believe he saw"},{"speaker":"Shaun Bagai","startTime":566.315,"endTime":569.165,"body":"similar traits and qualities,"},{"speaker":"Shaun Bagai","startTime":566.315,"endTime":569.165,"body":"and then helped set me on a"},{"speaker":"Shaun Bagai","startTime":569.165,"endTime":571.685,"body":"path, which he was reluctant to"},{"speaker":"Shaun Bagai","startTime":569.165,"endTime":571.685,"body":"talk about, I think, until he"},{"speaker":"Shaun Bagai","startTime":571.685,"endTime":573.065,"body":"got to know me better."},{"speaker":"John Simboli","startTime":573.0,"endTime":574.8,"body":"Why don't you take"},{"speaker":"John Simboli","startTime":573.0,"endTime":574.8,"body":"me a little bit through the path"},{"speaker":"John Simboli","startTime":574.8,"endTime":579.15,"body":"of how it was you picked out"},{"speaker":"John Simboli","startTime":574.8,"endTime":579.15,"body":"RenovoRx out of all the"},{"speaker":"John Simboli","startTime":579.15,"endTime":581.43,"body":"opportunities that you might"},{"speaker":"John Simboli","startTime":579.15,"endTime":581.43,"body":"have chosen? Why that one? What"},{"speaker":"John Simboli","startTime":581.43,"endTime":583.38,"body":"what was it that spoke to you"},{"speaker":"John Simboli","startTime":581.43,"endTime":583.38,"body":"about that one?"},{"speaker":"Shaun Bagai","startTime":583.279,"endTime":585.834,"body":"RenovRx, it was the"},{"speaker":"Shaun Bagai","startTime":583.279,"endTime":585.834,"body":"founder of the company. You"},{"speaker":"Shaun Bagai","startTime":585.889,"endTime":589.26,"body":"mentioned earlier relationships,"},{"speaker":"Shaun Bagai","startTime":585.889,"endTime":589.26,"body":"as a cardiologist by day job,"},{"speaker":"Shaun Bagai","startTime":589.315,"endTime":592.741,"body":"biomedical engineer by initial"},{"speaker":"Shaun Bagai","startTime":589.315,"endTime":592.741,"body":"training. I'd known him for now,"},{"speaker":"Shaun Bagai","startTime":592.795,"endTime":595.732,"body":"I'd say, almost pushing 30"},{"speaker":"Shaun Bagai","startTime":592.795,"endTime":595.732,"body":"years. So he was a research"},{"speaker":"Shaun Bagai","startTime":595.786,"endTime":599.266,"body":"fellow at Cleveland Clinic when"},{"speaker":"Shaun Bagai","startTime":595.786,"endTime":599.266,"body":"I first met him in my first job,"},{"speaker":"Shaun Bagai","startTime":599.321,"endTime":602.475,"body":"Transvascular, and then we"},{"speaker":"Shaun Bagai","startTime":599.321,"endTime":602.475,"body":"stayed in touch over the years."},{"speaker":"Shaun Bagai","startTime":602.529,"endTime":605.248,"body":"Once he moved to California,"},{"speaker":"Shaun Bagai","startTime":602.529,"endTime":605.248,"body":"became a full-fledged"},{"speaker":"Shaun Bagai","startTime":605.303,"endTime":608.239,"body":"cardiologist. I worked for"},{"speaker":"Shaun Bagai","startTime":605.303,"endTime":608.239,"body":"Medtronic. He was one of my"},{"speaker":"Shaun Bagai","startTime":608.294,"endTime":611.611,"body":"biggest customers in sales, and"},{"speaker":"Shaun Bagai","startTime":608.294,"endTime":611.611,"body":"he tapped me on the shoulder."},{"speaker":"Shaun Bagai","startTime":611.665,"endTime":614.765,"body":"And what attracted me to"},{"speaker":"Shaun Bagai","startTime":611.665,"endTime":614.765,"body":"RenovoRx is he was finding a way"},{"speaker":"Shaun Bagai","startTime":614.819,"endTime":617.973,"body":"to actually localize therapy for"},{"speaker":"Shaun Bagai","startTime":614.819,"endTime":617.973,"body":"cancer treatment, so they"},{"speaker":"Shaun Bagai","startTime":618.028,"endTime":621.454,"body":"wouldn't have the side effects."},{"speaker":"Shaun Bagai","startTime":618.028,"endTime":621.454,"body":"You'd have much better efficacy"},{"speaker":"Shaun Bagai","startTime":621.508,"endTime":625.043,"body":"in terms of driving chemotherapy"},{"speaker":"Shaun Bagai","startTime":621.508,"endTime":625.043,"body":"into tumors, and this is an area"},{"speaker":"Shaun Bagai","startTime":625.097,"endTime":627.979,"body":"of need, especially in"},{"speaker":"Shaun Bagai","startTime":625.097,"endTime":627.979,"body":"pancreatic cancer, where we've"},{"speaker":"Shaun Bagai","startTime":628.034,"endTime":631.188,"body":"spent the most of our time"},{"speaker":"Shaun Bagai","startTime":628.034,"endTime":631.188,"body":"focusing, where it's the bar is"},{"speaker":"Shaun Bagai","startTime":631.242,"endTime":634.287,"body":"so low to make a big impact,."},{"speaker":"Shaun Bagai","startTime":631.242,"endTime":634.287,"body":"And here was an avenue, an"},{"speaker":"Shaun Bagai","startTime":634.342,"endTime":637.659,"body":"opportunity to really make a"},{"speaker":"Shaun Bagai","startTime":634.342,"endTime":637.659,"body":"huge impact compared to previous"},{"speaker":"Shaun Bagai","startTime":637.713,"endTime":641.085,"body":"jobs where I believe we did make"},{"speaker":"Shaun Bagai","startTime":637.713,"endTime":641.085,"body":"an impact. So, the choice was"},{"speaker":"Shaun Bagai","startTime":641.139,"endTime":644.239,"body":"obvious there. I had several"},{"speaker":"Shaun Bagai","startTime":641.139,"endTime":644.239,"body":"companies and technologies I"},{"speaker":"Shaun Bagai","startTime":644.293,"endTime":647.012,"body":"looked at when I made the"},{"speaker":"Shaun Bagai","startTime":644.293,"endTime":647.012,"body":"transition, and this one"},{"speaker":"Shaun Bagai","startTime":647.067,"endTime":650.384,"body":"definitely spoke to me because I"},{"speaker":"Shaun Bagai","startTime":647.067,"endTime":650.384,"body":"feel like I could make a big"},{"speaker":"Shaun Bagai","startTime":650.438,"endTime":653.592,"body":"difference. It was also an"},{"speaker":"Shaun Bagai","startTime":650.438,"endTime":653.592,"body":"opportunity to take on a larger"},{"speaker":"Shaun Bagai","startTime":653.647,"endTime":657.127,"body":"leadership role as my first CEO"},{"speaker":"Shaun Bagai","startTime":653.647,"endTime":657.127,"body":"job. Fast forward, rewind to the"},{"speaker":"Shaun Bagai","startTime":657.182,"endTime":660.39,"body":"beginning. The first company I"},{"speaker":"Shaun Bagai","startTime":657.182,"endTime":660.39,"body":"was with, I was helping with"},{"speaker":"Shaun Bagai","startTime":660.444,"endTime":663.544,"body":"clinical. I was an intern. I was"},{"speaker":"Shaun Bagai","startTime":660.444,"endTime":663.544,"body":"helping with preclinical"},{"speaker":"Shaun Bagai","startTime":663.598,"endTime":666.916,"body":"research, helping with animal"},{"speaker":"Shaun Bagai","startTime":663.598,"endTime":666.916,"body":"studies, taking pictures of pig"},{"speaker":"Shaun Bagai","startTime":666.97,"endTime":670.342,"body":"hearts, packing catheter bags"},{"speaker":"Shaun Bagai","startTime":666.97,"endTime":670.342,"body":"for animal labs, taking notes. A"},{"speaker":"Shaun Bagai","startTime":670.396,"endTime":673.604,"body":"lot of intern-like grunt work."},{"speaker":"Shaun Bagai","startTime":670.396,"endTime":673.604,"body":"And once my CEO had told me,"},{"speaker":"Shaun Bagai","startTime":673.659,"endTime":676.922,"body":"\"Tell your boss you're not going"},{"speaker":"Shaun Bagai","startTime":673.659,"endTime":676.922,"body":"to med school, and see what"},{"speaker":"Shaun Bagai","startTime":676.976,"endTime":680.293,"body":"happens to your career. Make it"},{"speaker":"Shaun Bagai","startTime":676.976,"endTime":680.293,"body":"a tougher choice once you get"},{"speaker":"Shaun Bagai","startTime":680.348,"endTime":683.556,"body":"in. And after doing that, by the"},{"speaker":"Shaun Bagai","startTime":680.348,"endTime":683.556,"body":"time I got into med school"},{"speaker":"Shaun Bagai","startTime":683.61,"endTime":686.765,"body":"several months later, I was"},{"speaker":"Shaun Bagai","startTime":683.61,"endTime":686.765,"body":"managing animal studies. I was"},{"speaker":"Shaun Bagai","startTime":686.819,"endTime":690.082,"body":"managing the whole process of"},{"speaker":"Shaun Bagai","startTime":686.819,"endTime":690.082,"body":"the animal labs. I was writing"},{"speaker":"Shaun Bagai","startTime":690.136,"endTime":693.345,"body":"the protocols. I was really"},{"speaker":"Shaun Bagai","startTime":690.136,"endTime":693.345,"body":"owning and taking over a lot of"},{"speaker":"Shaun Bagai","startTime":693.399,"endTime":696.662,"body":"that area. I started flying to"},{"speaker":"Shaun Bagai","startTime":693.399,"endTime":696.662,"body":"Europe to train physicians. I"},{"speaker":"Shaun Bagai","startTime":696.716,"endTime":700.088,"body":"became one of the lead proctors"},{"speaker":"Shaun Bagai","startTime":696.716,"endTime":700.088,"body":"on how to teach the technology"},{"speaker":"Shaun Bagai","startTime":700.142,"endTime":703.079,"body":"that we're working on, and"},{"speaker":"Shaun Bagai","startTime":700.142,"endTime":703.079,"body":"really saw an avenue and an"},{"speaker":"Shaun Bagai","startTime":703.133,"endTime":706.505,"body":"interest, and my career starts"},{"speaker":"Shaun Bagai","startTime":703.133,"endTime":706.505,"body":"to take off. So, upon declining"},{"speaker":"Shaun Bagai","startTime":706.559,"endTime":709.876,"body":"med school, I went into clinical"},{"speaker":"Shaun Bagai","startTime":706.559,"endTime":709.876,"body":"research. The company saw my"},{"speaker":"Shaun Bagai","startTime":709.931,"endTime":712.758,"body":"talents in the area I was"},{"speaker":"Shaun Bagai","startTime":709.931,"endTime":712.758,"body":"working on. They taught me"},{"speaker":"Shaun Bagai","startTime":712.813,"endTime":715.912,"body":"clinical research through"},{"speaker":"Shaun Bagai","startTime":712.813,"endTime":715.912,"body":"courses, and by the time we got"},{"speaker":"Shaun Bagai","startTime":715.967,"endTime":719.121,"body":"acquired by Medtronic, I was"},{"speaker":"Shaun Bagai","startTime":715.967,"endTime":719.121,"body":"managing their whole clinical"},{"speaker":"Shaun Bagai","startTime":719.175,"endTime":722.492,"body":"research department. And so my"},{"speaker":"Shaun Bagai","startTime":719.175,"endTime":722.492,"body":"early start was heavily rooted"},{"speaker":"Shaun Bagai","startTime":722.547,"endTime":725.701,"body":"in the the science and research"},{"speaker":"Shaun Bagai","startTime":722.547,"endTime":725.701,"body":"and developing data, which"},{"speaker":"Shaun Bagai","startTime":725.755,"endTime":729.073,"body":"eventually turns into adoption"},{"speaker":"Shaun Bagai","startTime":725.755,"endTime":729.073,"body":"of new technologies, improving"},{"speaker":"Shaun Bagai","startTime":729.127,"endTime":732.118,"body":"safety and effectiveness. Then,"},{"speaker":"Shaun Bagai","startTime":729.127,"endTime":732.118,"body":"when we got acquired by"},{"speaker":"Shaun Bagai","startTime":732.172,"endTime":735.272,"body":"Medtronic, the same CEO and"},{"speaker":"Shaun Bagai","startTime":732.172,"endTime":735.272,"body":"other mentors said, \"Look, if"},{"speaker":"Shaun Bagai","startTime":735.326,"endTime":738.535,"body":"you're going to build and run"},{"speaker":"Shaun Bagai","startTime":735.326,"endTime":738.535,"body":"companies, you have to carry,"},{"speaker":"Shaun Bagai","startTime":738.589,"endTime":742.069,"body":"quote unquote, you have to carry"},{"speaker":"Shaun Bagai","startTime":738.589,"endTime":742.069,"body":"the bag. You have to go sell to"},{"speaker":"Shaun Bagai","startTime":742.124,"endTime":745.387,"body":"technology, understand what a"},{"speaker":"Shaun Bagai","startTime":742.124,"endTime":745.387,"body":"quota is. Understand what it's"},{"speaker":"Shaun Bagai","startTime":745.441,"endTime":748.921,"body":"like being in the field, working"},{"speaker":"Shaun Bagai","startTime":745.441,"endTime":748.921,"body":"with doctors, because then when"},{"speaker":"Shaun Bagai","startTime":748.976,"endTime":752.184,"body":"you build in technology, you"},{"speaker":"Shaun Bagai","startTime":748.976,"endTime":752.184,"body":"want to make sure you actually"},{"speaker":"Shaun Bagai","startTime":752.239,"endTime":755.338,"body":"have something that is sellable"},{"speaker":"Shaun Bagai","startTime":752.239,"endTime":755.338,"body":"to physicians and will be"},{"speaker":"Shaun Bagai","startTime":755.393,"endTime":758.547,"body":"adoptable. Which was a tough"},{"speaker":"Shaun Bagai","startTime":755.393,"endTime":758.547,"body":"lesson. It's a tough job, and"},{"speaker":"Shaun Bagai","startTime":758.601,"endTime":761.32,"body":"you've got to have a"},{"speaker":"Shaun Bagai","startTime":758.601,"endTime":761.32,"body":"differentiated technology and"},{"speaker":"Shaun Bagai","startTime":761.375,"endTime":764.637,"body":"learn to be an expert on the"},{"speaker":"Shaun Bagai","startTime":761.375,"endTime":764.637,"body":"technology you're selling. So I"},{"speaker":"Shaun Bagai","startTime":764.692,"endTime":767.846,"body":"went into sales, took the"},{"speaker":"Shaun Bagai","startTime":764.692,"endTime":767.846,"body":"opportunity to negotiate, flying"},{"speaker":"Shaun Bagai","startTime":767.9,"endTime":771.326,"body":"around the country for two years"},{"speaker":"Shaun Bagai","startTime":767.9,"endTime":771.326,"body":"to train their sales force and"},{"speaker":"Shaun Bagai","startTime":771.381,"endTime":774.154,"body":"the physicians on the technology"},{"speaker":"Shaun Bagai","startTime":771.381,"endTime":774.154,"body":"they acquired from"},{"speaker":"Shaun Bagai","startTime":774.208,"endTime":777.525,"body":"Transvascular, and then became a"},{"speaker":"Shaun Bagai","startTime":774.208,"endTime":777.525,"body":"senior coronary sales rep in"},{"speaker":"Shaun Bagai","startTime":777.58,"endTime":780.734,"body":"Medtronic for five years."},{"speaker":"Shaun Bagai","startTime":777.58,"endTime":780.734,"body":"Launched disruptive technologies"},{"speaker":"Shaun Bagai","startTime":780.788,"endTime":784.16,"body":"with new drug-coated stents for"},{"speaker":"Shaun Bagai","startTime":780.788,"endTime":784.16,"body":"coronary reuse back then, so I"},{"speaker":"Shaun Bagai","startTime":784.214,"endTime":787.477,"body":"took that opportunity to really"},{"speaker":"Shaun Bagai","startTime":784.214,"endTime":787.477,"body":"understand the sales process"},{"speaker":"Shaun Bagai","startTime":787.532,"endTime":790.849,"body":"cycle, be a sales rep. Then from"},{"speaker":"Shaun Bagai","startTime":787.532,"endTime":790.849,"body":"there, I built my career and"},{"speaker":"Shaun Bagai","startTime":790.903,"endTime":794.22,"body":"went back to startups. I love"},{"speaker":"Shaun Bagai","startTime":790.903,"endTime":794.22,"body":"the startup environment. I love"},{"speaker":"Shaun Bagai","startTime":794.275,"endTime":797.429,"body":"learning, changing, pivoting,"},{"speaker":"Shaun Bagai","startTime":794.275,"endTime":797.429,"body":"doing. The big companies are"},{"speaker":"Shaun Bagai","startTime":797.483,"endTime":800.8,"body":"good at scaling., we, as small"},{"speaker":"Shaun Bagai","startTime":797.483,"endTime":800.8,"body":"companies, are good at getting"},{"speaker":"Shaun Bagai","startTime":800.855,"endTime":803.302,"body":"things done fast and"},{"speaker":"Shaun Bagai","startTime":800.855,"endTime":803.302,"body":"inexpensively, and pivot"},{"speaker":"Shaun Bagai","startTime":803.356,"endTime":806.51,"body":"quickly, and so I went on to two"},{"speaker":"Shaun Bagai","startTime":803.356,"endTime":806.51,"body":"more companies already in"},{"speaker":"Shaun Bagai","startTime":806.565,"endTime":809.936,"body":"Heartflow. The first disruptive"},{"speaker":"Shaun Bagai","startTime":806.565,"endTime":809.936,"body":"and hypertension treatment, we"},{"speaker":"Shaun Bagai","startTime":809.991,"endTime":813.09,"body":"got acquired by Medtronic for a"},{"speaker":"Shaun Bagai","startTime":809.991,"endTime":813.09,"body":"billion dollars, and then"},{"speaker":"Shaun Bagai","startTime":813.145,"endTime":815.755,"body":"Heartflow disruptive and"},{"speaker":"Shaun Bagai","startTime":813.145,"endTime":815.755,"body":"coronary artery disease"},{"speaker":"Shaun Bagai","startTime":815.809,"endTime":819.072,"body":"diagnosis. So, kind of built the"},{"speaker":"Shaun Bagai","startTime":815.809,"endTime":819.072,"body":"career on clinical research"},{"speaker":"Shaun Bagai","startTime":819.127,"endTime":822.226,"body":"initially, sales, market"},{"speaker":"Shaun Bagai","startTime":819.127,"endTime":822.226,"body":"development, physician training,"},{"speaker":"Shaun Bagai","startTime":822.281,"endTime":825.326,"body":"learned the other pieces of"},{"speaker":"Shaun Bagai","startTime":822.281,"endTime":825.326,"body":"running a business along the"},{"speaker":"Shaun Bagai","startTime":825.38,"endTime":828.643,"body":"way, and then was able to take"},{"speaker":"Shaun Bagai","startTime":825.38,"endTime":828.643,"body":"over this job back about nine"},{"speaker":"Shaun Bagai","startTime":828.698,"endTime":829.84,"body":"and a half years ago."},{"speaker":"John Simboli","startTime":829.9,"endTime":832.33,"body":"There seems"},{"speaker":"John Simboli","startTime":829.9,"endTime":832.33,"body":"sometimes to be a sharp divide"},{"speaker":"John Simboli","startTime":832.45,"endTime":835.03,"body":"between people who are"},{"speaker":"John Simboli","startTime":832.45,"endTime":835.03,"body":"interested in medical technology"},{"speaker":"John Simboli","startTime":835.09,"endTime":837.88,"body":"and people interested in"},{"speaker":"John Simboli","startTime":835.09,"endTime":837.88,"body":"therapeutics, and it sounds like"},{"speaker":"John Simboli","startTime":837.97,"endTime":840.99,"body":"you've been interested in both,"},{"speaker":"John Simboli","startTime":837.97,"endTime":840.99,"body":"and your company is following"},{"speaker":"John Simboli","startTime":841.05,"endTime":845.94,"body":"both pathways. So, was there"},{"speaker":"John Simboli","startTime":841.05,"endTime":845.94,"body":"like a roadmap you felt you had"},{"speaker":"John Simboli","startTime":845.97,"endTime":848.37,"body":"to choose, or did you want to"},{"speaker":"John Simboli","startTime":845.97,"endTime":848.37,"body":"pull the two together?"},{"speaker":"Shaun Bagai","startTime":848.9,"endTime":851.6,"body":"It's an interesting"},{"speaker":"Shaun Bagai","startTime":848.9,"endTime":851.6,"body":"question because I've always"},{"speaker":"Shaun Bagai","startTime":851.6,"endTime":853.88,"body":"been interested in the device"},{"speaker":"Shaun Bagai","startTime":851.6,"endTime":853.88,"body":"side because you can touch it"},{"speaker":"Shaun Bagai","startTime":853.88,"endTime":857.81,"body":"and feel it. It's there's a tool"},{"speaker":"Shaun Bagai","startTime":853.88,"endTime":857.81,"body":"in your hand, you can see it"},{"speaker":"Shaun Bagai","startTime":857.81,"endTime":861.53,"body":"being used either you know"},{"speaker":"Shaun Bagai","startTime":857.81,"endTime":861.53,"body":"surgically or for our catheter"},{"speaker":"Shaun Bagai","startTime":861.53,"endTime":864.77,"body":"under image guidance."},{"speaker":"Shaun Bagai","startTime":861.53,"endTime":864.77,"body":"Therapeutics always seemed"},{"speaker":"Shaun Bagai","startTime":864.77,"endTime":869.0,"body":"different to me because you"},{"speaker":"Shaun Bagai","startTime":864.77,"endTime":869.0,"body":"can't touch it, feel it, see it,"},{"speaker":"Shaun Bagai","startTime":869.0,"endTime":872.435,"body":"and it was a little more"},{"speaker":"Shaun Bagai","startTime":869.0,"endTime":872.435,"body":"distant. And really, us turning"},{"speaker":"Shaun Bagai","startTime":872.435,"endTime":876.575,"body":"into a biotech therapeutic"},{"speaker":"Shaun Bagai","startTime":872.435,"endTime":876.575,"body":"company was more a matter of"},{"speaker":"Shaun Bagai","startTime":876.575,"endTime":879.965,"body":"both opportunity and need."},{"speaker":"Shaun Bagai","startTime":876.575,"endTime":879.965,"body":"Earlier on, it was we had a"},{"speaker":"Shaun Bagai","startTime":879.965,"endTime":883.175,"body":"device, a delivery system that"},{"speaker":"Shaun Bagai","startTime":879.965,"endTime":883.175,"body":"could get therapy to where it"},{"speaker":"Shaun Bagai","startTime":883.175,"endTime":886.175,"body":"matters in a manner that no one"},{"speaker":"Shaun Bagai","startTime":883.175,"endTime":886.175,"body":"else had discovered before. So"},{"speaker":"Shaun Bagai","startTime":886.175,"endTime":890.315,"body":"we invented and developed this"},{"speaker":"Shaun Bagai","startTime":886.175,"endTime":890.315,"body":"whole new platform and patented"},{"speaker":"Shaun Bagai","startTime":890.315,"endTime":894.965,"body":"this concept of pushing drugs"},{"speaker":"Shaun Bagai","startTime":890.315,"endTime":894.965,"body":"across vessel walls, as so it"},{"speaker":"Shaun Bagai","startTime":894.965,"endTime":897.56,"body":"really fits to my device"},{"speaker":"Shaun Bagai","startTime":894.965,"endTime":897.56,"body":"background. Now, having said"},{"speaker":"Shaun Bagai","startTime":897.56,"endTime":900.41,"body":"that, to make the impact, you"},{"speaker":"Shaun Bagai","startTime":897.56,"endTime":900.41,"body":"need to get drugs places. And"},{"speaker":"Shaun Bagai","startTime":900.41,"endTime":905.21,"body":"that's when we had an"},{"speaker":"Shaun Bagai","startTime":900.41,"endTime":905.21,"body":"opportunity and a block where we"},{"speaker":"Shaun Bagai","startTime":905.21,"endTime":909.89,"body":"wanted to get on label for a"},{"speaker":"Shaun Bagai","startTime":905.21,"endTime":909.89,"body":"certain indication of the device"},{"speaker":"Shaun Bagai","startTime":909.89,"endTime":914.33,"body":"and also get reimbursement that"},{"speaker":"Shaun Bagai","startTime":909.89,"endTime":914.33,"body":"would reward us for spending the"},{"speaker":"Shaun Bagai","startTime":914.33,"endTime":916.4,"body":"money on the research and reward"},{"speaker":"Shaun Bagai","startTime":914.33,"endTime":916.4,"body":"my shareholders for spending the"},{"speaker":"Shaun Bagai","startTime":916.4,"endTime":919.355,"body":"money on research to prove the"},{"speaker":"Shaun Bagai","startTime":916.4,"endTime":919.355,"body":"technology really works, and so"},{"speaker":"Shaun Bagai","startTime":919.355,"endTime":922.025,"body":"the drug device combination"},{"speaker":"Shaun Bagai","startTime":919.355,"endTime":922.025,"body":"pathway made sense to us. We got"},{"speaker":"Shaun Bagai","startTime":922.025,"endTime":925.355,"body":"orphan drug designation. We're"},{"speaker":"Shaun Bagai","startTime":922.025,"endTime":925.355,"body":"using a drug which we know works"},{"speaker":"Shaun Bagai","startTime":925.355,"endTime":928.235,"body":"in certain areas, but can't work"},{"speaker":"Shaun Bagai","startTime":925.355,"endTime":928.235,"body":"in tumors like pancreatic"},{"speaker":"Shaun Bagai","startTime":928.235,"endTime":932.255,"body":"cancers because it doesn't get"},{"speaker":"Shaun Bagai","startTime":928.235,"endTime":932.255,"body":"there. So it became more of a"},{"speaker":"Shaun Bagai","startTime":932.255,"endTime":935.885,"body":"shift or an accommodation out of"},{"speaker":"Shaun Bagai","startTime":932.255,"endTime":935.885,"body":"both necessity on a business"},{"speaker":"Shaun Bagai","startTime":935.885,"endTime":939.305,"body":"standpoint and out of potential"},{"speaker":"Shaun Bagai","startTime":935.885,"endTime":939.305,"body":"impact in having a combination"},{"speaker":"Shaun Bagai","startTime":939.305,"endTime":942.77,"body":"product that would really make a"},{"speaker":"Shaun Bagai","startTime":939.305,"endTime":942.77,"body":"big difference. So I enjoy both"},{"speaker":"Shaun Bagai","startTime":942.77,"endTime":945.44,"body":"sides of kind of the pharma"},{"speaker":"Shaun Bagai","startTime":942.77,"endTime":945.44,"body":"biotech world and the device"},{"speaker":"Shaun Bagai","startTime":945.44,"endTime":948.62,"body":"world. But it's got this device"},{"speaker":"Shaun Bagai","startTime":945.44,"endTime":948.62,"body":"at the core, so it does go back"},{"speaker":"Shaun Bagai","startTime":948.62,"endTime":950.0,"body":"to my roots."},{"speaker":"John Simboli","startTime":950.0,"endTime":952.67,"body":"I've heard people"},{"speaker":"John Simboli","startTime":950.0,"endTime":952.67,"body":"say that to be really interested"},{"speaker":"John Simboli","startTime":952.67,"endTime":955.43,"body":"in the therapy side, the"},{"speaker":"John Simboli","startTime":952.67,"endTime":955.43,"body":"therapeutic side, you have to"},{"speaker":"John Simboli","startTime":955.43,"endTime":959.99,"body":"have, your timeline has to"},{"speaker":"John Simboli","startTime":955.43,"endTime":959.99,"body":"account for the fact that you"},{"speaker":"John Simboli","startTime":959.99,"endTime":963.92,"body":"might be at it for 10 years or"},{"speaker":"John Simboli","startTime":959.99,"endTime":963.92,"body":"so before you even know how it's"},{"speaker":"John Simboli","startTime":963.92,"endTime":967.34,"body":"going to work out. With a"},{"speaker":"John Simboli","startTime":963.92,"endTime":967.34,"body":"device, it's a shorter cycle"},{"speaker":"John Simboli","startTime":967.34,"endTime":972.74,"body":"often, right? It can vary, but"},{"speaker":"John Simboli","startTime":967.34,"endTime":972.74,"body":"also inherent in that is is the"},{"speaker":"John Simboli","startTime":972.74,"endTime":976.475,"body":"question of impact on the"},{"speaker":"John Simboli","startTime":972.74,"endTime":976.475,"body":"patients. To use the word you're"},{"speaker":"John Simboli","startTime":976.475,"endTime":979.625,"body":"using a moment ago, so what I'm"},{"speaker":"John Simboli","startTime":976.475,"endTime":979.625,"body":"trying to get at is when your"},{"speaker":"John Simboli","startTime":979.625,"endTime":983.345,"body":"company is strictly developing"},{"speaker":"John Simboli","startTime":979.625,"endTime":983.345,"body":"therapies, it's very hard, I"},{"speaker":"John Simboli","startTime":983.345,"endTime":987.455,"body":"would think, to have connections"},{"speaker":"John Simboli","startTime":983.345,"endTime":987.455,"body":"to patients to understand how"},{"speaker":"John Simboli","startTime":987.455,"endTime":990.935,"body":"it's working because clinical"},{"speaker":"John Simboli","startTime":987.455,"endTime":990.935,"body":"trials take a long time. Did you"},{"speaker":"John Simboli","startTime":990.935,"endTime":993.605,"body":"have any experience on the"},{"speaker":"John Simboli","startTime":990.935,"endTime":993.605,"body":"device side where you could"},{"speaker":"John Simboli","startTime":993.605,"endTime":996.695,"body":"actually see that the device was"},{"speaker":"John Simboli","startTime":993.605,"endTime":996.695,"body":"working? You could see the"},{"speaker":"John Simboli","startTime":996.695,"endTime":999.41,"body":"patient. You could be present."},{"speaker":"John Simboli","startTime":996.695,"endTime":999.41,"body":"You could witness it. Is that"},{"speaker":"John Simboli","startTime":999.41,"endTime":1001.21,"body":"was that part of your"},{"speaker":"John Simboli","startTime":999.41,"endTime":1001.21,"body":"development as well?"},{"speaker":"Shaun Bagai","startTime":1001.0,"endTime":1002.883,"body":"Yeah, I think"},{"speaker":"Shaun Bagai","startTime":1001.0,"endTime":1002.883,"body":"that's what gave me the"},{"speaker":"Shaun Bagai","startTime":1002.934,"endTime":1005.633,"body":"confidence to keep going and"},{"speaker":"Shaun Bagai","startTime":1002.934,"endTime":1005.633,"body":"knowing I made the right"},{"speaker":"Shaun Bagai","startTime":1005.684,"endTime":1008.331,"body":"decision because every"},{"speaker":"Shaun Bagai","startTime":1005.684,"endTime":1008.331,"body":"technology I've worked on, we"},{"speaker":"Shaun Bagai","startTime":1008.382,"endTime":1010.928,"body":"almost got the instant"},{"speaker":"Shaun Bagai","startTime":1008.382,"endTime":1010.928,"body":"gratification of seeing the"},{"speaker":"Shaun Bagai","startTime":1010.979,"endTime":1013.932,"body":"results of our technology. I"},{"speaker":"Shaun Bagai","startTime":1010.979,"endTime":1013.932,"body":"take the first company out of"},{"speaker":"Shaun Bagai","startTime":1013.983,"endTime":1016.986,"body":"college, Transvascular. We"},{"speaker":"Shaun Bagai","startTime":1013.983,"endTime":1016.986,"body":"developed a new device that went"},{"speaker":"Shaun Bagai","startTime":1017.037,"endTime":1020.143,"body":"inside leg arteries that could"},{"speaker":"Shaun Bagai","startTime":1017.037,"endTime":1020.143,"body":"open up completely blocked leg"},{"speaker":"Shaun Bagai","startTime":1020.194,"endTime":1023.503,"body":"arteries, and my job once we got"},{"speaker":"Shaun Bagai","startTime":1020.194,"endTime":1023.503,"body":"acquired by Medtronic was to fly"},{"speaker":"Shaun Bagai","startTime":1023.554,"endTime":1026.406,"body":"around the country and train"},{"speaker":"Shaun Bagai","startTime":1023.554,"endTime":1026.406,"body":"physicians on the procedure"},{"speaker":"Shaun Bagai","startTime":1026.456,"endTime":1029.359,"body":"using the device. And there were"},{"speaker":"Shaun Bagai","startTime":1026.456,"endTime":1029.359,"body":"many circumstances where"},{"speaker":"Shaun Bagai","startTime":1029.409,"endTime":1032.261,"body":"literally a patient was"},{"speaker":"Shaun Bagai","startTime":1029.409,"endTime":1032.261,"body":"diabetic, they had a blocked leg"},{"speaker":"Shaun Bagai","startTime":1032.312,"endTime":1035.417,"body":"artery, they have gangrenous"},{"speaker":"Shaun Bagai","startTime":1032.312,"endTime":1035.417,"body":"feet because they're not getting"},{"speaker":"Shaun Bagai","startTime":1035.468,"endTime":1038.625,"body":"blood flow, and they basically"},{"speaker":"Shaun Bagai","startTime":1035.468,"endTime":1038.625,"body":"said, \"Look, Sean, if you can't"},{"speaker":"Shaun Bagai","startTime":1038.676,"endTime":1041.476,"body":"help me open this leg, the"},{"speaker":"Shaun Bagai","startTime":1038.676,"endTime":1041.476,"body":"patient's having his leg get"},{"speaker":"Shaun Bagai","startTime":1041.527,"endTime":1044.582,"body":"painted next Friday,\" and then"},{"speaker":"Shaun Bagai","startTime":1041.527,"endTime":1044.582,"body":"there was a you know specific"},{"speaker":"Shaun Bagai","startTime":1044.633,"endTime":1047.789,"body":"patient I can remember. And I"},{"speaker":"Shaun Bagai","startTime":1044.633,"endTime":1047.789,"body":"you know went in there difficult"},{"speaker":"Shaun Bagai","startTime":1047.84,"endTime":1050.691,"body":"procedure and impossible to"},{"speaker":"Shaun Bagai","startTime":1047.84,"endTime":1050.691,"body":"open, but our technology and"},{"speaker":"Shaun Bagai","startTime":1050.742,"endTime":1054.001,"body":"device was different because it"},{"speaker":"Shaun Bagai","startTime":1050.742,"endTime":1054.001,"body":"was able to get around blockages"},{"speaker":"Shaun Bagai","startTime":1054.052,"endTime":1057.208,"body":"and reopen arteries that were"},{"speaker":"Shaun Bagai","startTime":1054.052,"endTime":1057.208,"body":"impossible to reopen, and seeing"},{"speaker":"Shaun Bagai","startTime":1057.259,"endTime":1060.416,"body":"blood flow down to the toes and"},{"speaker":"Shaun Bagai","startTime":1057.259,"endTime":1060.416,"body":"knowing that I just saved this"},{"speaker":"Shaun Bagai","startTime":1060.467,"endTime":1063.624,"body":"patient's leg, you know, with"},{"speaker":"Shaun Bagai","startTime":1060.467,"endTime":1063.624,"body":"the help of my technology and my"},{"speaker":"Shaun Bagai","startTime":1063.674,"endTime":1066.678,"body":"coaching to this physician, it"},{"speaker":"Shaun Bagai","startTime":1063.674,"endTime":1066.678,"body":"was extremely rewarding. And"},{"speaker":"Shaun Bagai","startTime":1066.729,"endTime":1069.326,"body":"this happened. I think I"},{"speaker":"Shaun Bagai","startTime":1066.729,"endTime":1069.326,"body":"probably coached about 500"},{"speaker":"Shaun Bagai","startTime":1069.377,"endTime":1072.533,"body":"procedures during my tenure in"},{"speaker":"Shaun Bagai","startTime":1069.377,"endTime":1072.533,"body":"that position over a year and a"},{"speaker":"Shaun Bagai","startTime":1072.584,"endTime":1075.334,"body":"half, and flew around the"},{"speaker":"Shaun Bagai","startTime":1072.584,"endTime":1075.334,"body":"country every day. So it was"},{"speaker":"Shaun Bagai","startTime":1075.385,"endTime":1077.93,"body":"gratifying to actually see"},{"speaker":"Shaun Bagai","startTime":1075.385,"endTime":1077.93,"body":"firsthand the impact on"},{"speaker":"Shaun Bagai","startTime":1077.981,"endTime":1081.036,"body":"individual patients by me, you"},{"speaker":"Shaun Bagai","startTime":1077.981,"endTime":1081.036,"body":"know, sometimes scrubbing in,"},{"speaker":"Shaun Bagai","startTime":1081.087,"endTime":1084.346,"body":"being next to physicians at the"},{"speaker":"Shaun Bagai","startTime":1081.087,"endTime":1084.346,"body":"table on a technology I'd helped"},{"speaker":"Shaun Bagai","startTime":1084.396,"endTime":1087.502,"body":"develop, and now getting out"},{"speaker":"Shaun Bagai","startTime":1084.396,"endTime":1087.502,"body":"there and full well knowing that"},{"speaker":"Shaun Bagai","startTime":1087.553,"endTime":1090.71,"body":"this doctor is going to do this"},{"speaker":"Shaun Bagai","startTime":1087.553,"endTime":1090.71,"body":"again and again and again, and"},{"speaker":"Shaun Bagai","startTime":1090.761,"endTime":1093.815,"body":"then teach his fellows to do"},{"speaker":"Shaun Bagai","startTime":1090.761,"endTime":1093.815,"body":"this again and again and again,"},{"speaker":"Shaun Bagai","startTime":1093.866,"endTime":1097.176,"body":"and that was my first company at"},{"speaker":"Shaun Bagai","startTime":1093.866,"endTime":1097.176,"body":"college. And and then from that,"},{"speaker":"Shaun Bagai","startTime":1097.227,"endTime":1100.434,"body":"Ardian was very similar. We had"},{"speaker":"Shaun Bagai","startTime":1097.227,"endTime":1100.434,"body":"patients that we treated with a"},{"speaker":"Shaun Bagai","startTime":1100.485,"endTime":1103.387,"body":"catheter to reduce blood"},{"speaker":"Shaun Bagai","startTime":1100.485,"endTime":1103.387,"body":"pressure, and I remember talking"},{"speaker":"Shaun Bagai","startTime":1103.438,"endTime":1106.544,"body":"to physicians after we treated"},{"speaker":"Shaun Bagai","startTime":1103.438,"endTime":1106.544,"body":"them. I used to fly to Germany"},{"speaker":"Shaun Bagai","startTime":1106.595,"endTime":1109.293,"body":"almost every week back then to"},{"speaker":"Shaun Bagai","startTime":1106.595,"endTime":1109.293,"body":"train the doctors, and"},{"speaker":"Shaun Bagai","startTime":1109.344,"endTime":1112.094,"body":"eventually I helped them"},{"speaker":"Shaun Bagai","startTime":1109.344,"endTime":1112.094,"body":"commercialize. And talking to"},{"speaker":"Shaun Bagai","startTime":1112.144,"endTime":1115.097,"body":"physicians, saying, \"Remember"},{"speaker":"Shaun Bagai","startTime":1112.144,"endTime":1115.097,"body":"that patient we treated last"},{"speaker":"Shaun Bagai","startTime":1115.148,"endTime":1118.305,"body":"month? He went from 13 meds down"},{"speaker":"Shaun Bagai","startTime":1115.148,"endTime":1118.305,"body":"to two, and now he's actually"},{"speaker":"Shaun Bagai","startTime":1118.356,"endTime":1121.411,"body":"sleeping every night, staying"},{"speaker":"Shaun Bagai","startTime":1118.356,"endTime":1121.411,"body":"awake all day, and got his job"},{"speaker":"Shaun Bagai","startTime":1121.462,"endTime":1124.567,"body":"back because he can function as"},{"speaker":"Shaun Bagai","startTime":1121.462,"endTime":1124.567,"body":"a human being. So I did get a"},{"speaker":"Shaun Bagai","startTime":1124.618,"endTime":1127.673,"body":"lot of instant gratification"},{"speaker":"Shaun Bagai","startTime":1124.618,"endTime":1127.673,"body":"from seeing the effect of these"},{"speaker":"Shaun Bagai","startTime":1127.724,"endTime":1130.677,"body":"device treatments on patients"},{"speaker":"Shaun Bagai","startTime":1127.724,"endTime":1130.677,"body":"pretty quickly. And now with"},{"speaker":"Shaun Bagai","startTime":1130.728,"endTime":1133.885,"body":"Renovo, same thing. If  you go"},{"speaker":"Shaun Bagai","startTime":1130.728,"endTime":1133.885,"body":"to the investors section of our"},{"speaker":"Shaun Bagai","startTime":1133.936,"endTime":1136.787,"body":"website and go under clinical"},{"speaker":"Shaun Bagai","startTime":1133.936,"endTime":1136.787,"body":"stories, there are several"},{"speaker":"Shaun Bagai","startTime":1136.838,"endTime":1139.994,"body":"mainstream news stories about"},{"speaker":"Shaun Bagai","startTime":1136.838,"endTime":1139.994,"body":"our patients who can function as"},{"speaker":"Shaun Bagai","startTime":1140.045,"endTime":1142.846,"body":"chemo patients with pancreatic"},{"speaker":"Shaun Bagai","startTime":1140.045,"endTime":1142.846,"body":"cancer, and seeing these"},{"speaker":"Shaun Bagai","startTime":1142.896,"endTime":1146.104,"body":"patients firsthand, as much as"},{"speaker":"Shaun Bagai","startTime":1142.896,"endTime":1146.104,"body":"I'm the CEO of a Nasdaq company,"},{"speaker":"Shaun Bagai","startTime":1146.155,"endTime":1149.363,"body":"I do get the opportunity to go"},{"speaker":"Shaun Bagai","startTime":1146.155,"endTime":1149.363,"body":"to the operating room. I used to"},{"speaker":"Shaun Bagai","startTime":1149.413,"endTime":1152.366,"body":"be one of the proctors of this"},{"speaker":"Shaun Bagai","startTime":1149.413,"endTime":1152.366,"body":"technology when we were two"},{"speaker":"Shaun Bagai","startTime":1152.417,"endTime":1155.37,"body":"people in the company, and I"},{"speaker":"Shaun Bagai","startTime":1152.417,"endTime":1155.37,"body":"still get to to watch or help"},{"speaker":"Shaun Bagai","startTime":1155.421,"endTime":1158.629,"body":"coach the procedure sometimes."},{"speaker":"Shaun Bagai","startTime":1155.421,"endTime":1158.629,"body":"And I see the patients come into"},{"speaker":"Shaun Bagai","startTime":1158.68,"endTime":1161.786,"body":"the operating room, and I see"},{"speaker":"Shaun Bagai","startTime":1158.68,"endTime":1161.786,"body":"them for their first treatment,"},{"speaker":"Shaun Bagai","startTime":1161.836,"endTime":1164.84,"body":"and they're in a wheelchair,"},{"speaker":"Shaun Bagai","startTime":1161.836,"endTime":1164.84,"body":"debilitated from chemotherapy."},{"speaker":"Shaun Bagai","startTime":1164.891,"endTime":1167.895,"body":"And now, in the fourth, fifth,"},{"speaker":"Shaun Bagai","startTime":1164.891,"endTime":1167.895,"body":"sixth treatment, because our"},{"speaker":"Shaun Bagai","startTime":1167.946,"endTime":1171.001,"body":"therapy doesn't have the side"},{"speaker":"Shaun Bagai","startTime":1167.946,"endTime":1171.001,"body":"effects, watching them walk in"},{"speaker":"Shaun Bagai","startTime":1171.052,"endTime":1174.208,"body":"with spunk and get on the table"},{"speaker":"Shaun Bagai","startTime":1171.052,"endTime":1174.208,"body":"and get treated and get out of"},{"speaker":"Shaun Bagai","startTime":1174.259,"endTime":1177.212,"body":"there in an hour and a half, I"},{"speaker":"Shaun Bagai","startTime":1174.259,"endTime":1177.212,"body":"can see the material impact"},{"speaker":"Shaun Bagai","startTime":1177.263,"endTime":1180.115,"body":"we're making on these patients'"},{"speaker":"Shaun Bagai","startTime":1177.263,"endTime":1180.115,"body":"lives, which is amazing."},{"speaker":"John Simboli","startTime":1180.25,"endTime":1183.6,"body":"Did the experience"},{"speaker":"John Simboli","startTime":1180.25,"endTime":1183.6,"body":"you had being around physicians,"},{"speaker":"John Simboli","startTime":1184.17,"endTime":1186.45,"body":"you know, almost every day? It"},{"speaker":"John Simboli","startTime":1184.17,"endTime":1186.45,"body":"sounds like for a number of"},{"speaker":"John Simboli","startTime":1186.51,"endTime":1189.33,"body":"years. Did that did that"},{"speaker":"John Simboli","startTime":1186.51,"endTime":1189.33,"body":"experience teach anything about"},{"speaker":"John Simboli","startTime":1189.54,"endTime":1192.96,"body":"your job as a CEO that did give"},{"speaker":"John Simboli","startTime":1189.54,"endTime":1192.96,"body":"you insight you might not have"},{"speaker":"John Simboli","startTime":1192.99,"endTime":1195.78,"body":"had if you hadn't had that"},{"speaker":"John Simboli","startTime":1192.99,"endTime":1195.78,"body":"carrying the bag experience?"},{"speaker":"Shaun Bagai","startTime":1196.03,"endTime":1199.93,"body":"100% the The"},{"speaker":"Shaun Bagai","startTime":1196.03,"endTime":1199.93,"body":"biggest challenge with new"},{"speaker":"Shaun Bagai","startTime":1200.05,"endTime":1204.16,"body":"medical technologies is changing"},{"speaker":"Shaun Bagai","startTime":1200.05,"endTime":1204.16,"body":"physician behavior. Physicians"},{"speaker":"Shaun Bagai","startTime":1204.16,"endTime":1208.81,"body":"go through years of training to"},{"speaker":"Shaun Bagai","startTime":1204.16,"endTime":1208.81,"body":"do a thing a certain way, and"},{"speaker":"Shaun Bagai","startTime":1208.81,"endTime":1211.96,"body":"once they're done with all that"},{"speaker":"Shaun Bagai","startTime":1208.81,"endTime":1211.96,"body":"training, then they then teach"},{"speaker":"Shaun Bagai","startTime":1211.96,"endTime":1215.41,"body":"everyone that they train to do"},{"speaker":"Shaun Bagai","startTime":1211.96,"endTime":1215.41,"body":"the same thing the same way. And"},{"speaker":"Shaun Bagai","startTime":1215.41,"endTime":1218.32,"body":"to go in there and tell a"},{"speaker":"Shaun Bagai","startTime":1215.41,"endTime":1218.32,"body":"physician what you've been"},{"speaker":"Shaun Bagai","startTime":1218.32,"endTime":1221.365,"body":"learning and doing for the last"},{"speaker":"Shaun Bagai","startTime":1218.32,"endTime":1221.365,"body":"15 years is no longer the best"},{"speaker":"Shaun Bagai","startTime":1221.365,"endTime":1224.485,"body":"way. Do it this way instead is"},{"speaker":"Shaun Bagai","startTime":1221.365,"endTime":1224.485,"body":"very challenging and very"},{"speaker":"Shaun Bagai","startTime":1224.485,"endTime":1227.635,"body":"difficult. And understanding"},{"speaker":"Shaun Bagai","startTime":1224.485,"endTime":1227.635,"body":"that at the core level in the"},{"speaker":"Shaun Bagai","startTime":1227.635,"endTime":1230.605,"body":"operating room is a great way to"},{"speaker":"Shaun Bagai","startTime":1227.635,"endTime":1230.605,"body":"truly understand that. And now"},{"speaker":"Shaun Bagai","startTime":1230.605,"endTime":1233.725,"body":"running a business and over"},{"speaker":"Shaun Bagai","startTime":1230.605,"endTime":1233.725,"body":"commercializing, understanding"},{"speaker":"Shaun Bagai","startTime":1233.725,"endTime":1236.905,"body":"what it takes to change that"},{"speaker":"Shaun Bagai","startTime":1233.725,"endTime":1236.905,"body":"physician behavior is paramount"},{"speaker":"Shaun Bagai","startTime":1236.905,"endTime":1239.485,"body":"to success of a new medical"},{"speaker":"Shaun Bagai","startTime":1236.905,"endTime":1239.485,"body":"technology."},{"speaker":"John Simboli","startTime":1239.57,"endTime":1242.57,"body":"When people say to"},{"speaker":"John Simboli","startTime":1239.57,"endTime":1242.57,"body":"you who is RenovoRx, and you"},{"speaker":"John Simboli","startTime":1242.57,"endTime":1245.45,"body":"want to give a concise answer."},{"speaker":"John Simboli","startTime":1242.57,"endTime":1245.45,"body":"What path do you go down? What"},{"speaker":"John Simboli","startTime":1245.45,"endTime":1246.29,"body":"do you have to say?"},{"speaker":"Shaun Bagai","startTime":1246.6,"endTime":1248.64,"body":"So generally,"},{"speaker":"Shaun Bagai","startTime":1246.6,"endTime":1248.64,"body":"physicians have to choose"},{"speaker":"Shaun Bagai","startTime":1248.64,"endTime":1252.78,"body":"between really efficacy and side"},{"speaker":"Shaun Bagai","startTime":1248.64,"endTime":1252.78,"body":"effects, and it's a matter of"},{"speaker":"Shaun Bagai","startTime":1252.78,"endTime":1257.04,"body":"how much drug can we give"},{"speaker":"Shaun Bagai","startTime":1252.78,"endTime":1257.04,"body":"without causing such damage to"},{"speaker":"Shaun Bagai","startTime":1257.04,"endTime":1260.73,"body":"the patient that we can actually"},{"speaker":"Shaun Bagai","startTime":1257.04,"endTime":1260.73,"body":"treat the tumor. And what we"},{"speaker":"Shaun Bagai","startTime":1260.73,"endTime":1263.64,"body":"found at RenovoRx is we don't"},{"speaker":"Shaun Bagai","startTime":1260.73,"endTime":1263.64,"body":"have to make that choice. Is"},{"speaker":"Shaun Bagai","startTime":1263.64,"endTime":1266.82,"body":"we're trying to develop new"},{"speaker":"Shaun Bagai","startTime":1263.64,"endTime":1266.82,"body":"therapies based on our platform"},{"speaker":"Shaun Bagai","startTime":1266.82,"endTime":1271.065,"body":"that can drive chemotherapy"},{"speaker":"Shaun Bagai","startTime":1266.82,"endTime":1271.065,"body":"directly in the tumor at levels"},{"speaker":"Shaun Bagai","startTime":1271.065,"endTime":1273.435,"body":"that can actually affect the"},{"speaker":"Shaun Bagai","startTime":1271.065,"endTime":1273.435,"body":"tumor where patients can live"},{"speaker":"Shaun Bagai","startTime":1273.435,"endTime":1276.375,"body":"longer. But on the flip side,"},{"speaker":"Shaun Bagai","startTime":1273.435,"endTime":1276.375,"body":"you're not giving up the quality"},{"speaker":"Shaun Bagai","startTime":1276.375,"endTime":1280.965,"body":"of life. You're not giving up"},{"speaker":"Shaun Bagai","startTime":1276.375,"endTime":1280.965,"body":"the fact you have to be chemo"},{"speaker":"Shaun Bagai","startTime":1280.965,"endTime":1284.655,"body":"laden on a couch, not eating,"},{"speaker":"Shaun Bagai","startTime":1280.965,"endTime":1284.655,"body":"not working, not sleeping, not"},{"speaker":"Shaun Bagai","startTime":1284.655,"endTime":1287.715,"body":"being able to do activities, and"},{"speaker":"Shaun Bagai","startTime":1284.655,"endTime":1287.715,"body":"we found this excellent balance"},{"speaker":"Shaun Bagai","startTime":1287.715,"endTime":1291.225,"body":"of very low risk, very low side"},{"speaker":"Shaun Bagai","startTime":1287.715,"endTime":1291.225,"body":"effects, with potential for"},{"speaker":"Shaun Bagai","startTime":1291.225,"endTime":1294.75,"body":"extending life. So, as patients"},{"speaker":"Shaun Bagai","startTime":1291.225,"endTime":1294.75,"body":"with cancer are trying to extend"},{"speaker":"Shaun Bagai","startTime":1294.75,"endTime":1297.51,"body":"life as long as possible, it's"},{"speaker":"Shaun Bagai","startTime":1294.75,"endTime":1297.51,"body":"actually a life worth living."},{"speaker":"Shaun Bagai","startTime":1297.57,"endTime":1299.28,"body":"And I think that's the biggest"},{"speaker":"Shaun Bagai","startTime":1297.57,"endTime":1299.28,"body":"difference that we've seen in"},{"speaker":"Shaun Bagai","startTime":1299.28,"endTime":1302.85,"body":"our technology is it's not a"},{"speaker":"Shaun Bagai","startTime":1299.28,"endTime":1302.85,"body":"trade-off, but it's hopefully a"},{"speaker":"Shaun Bagai","startTime":1302.85,"endTime":1306.03,"body":"benefit on both sides of that"},{"speaker":"Shaun Bagai","startTime":1302.85,"endTime":1306.03,"body":"coin, both quality of life and"},{"speaker":"John Simboli","startTime":1306.0,"endTime":1311.01,"body":"with me a layman's"},{"speaker":"John Simboli","startTime":1306.0,"endTime":1311.01,"body":"description of how the platform"},{"speaker":"John Simboli","startTime":1306.03,"endTime":1306.69,"body":"living longer."},{"speaker":"John Simboli","startTime":1311.01,"endTime":1311.67,"body":"works?"},{"speaker":"Shaun Bagai","startTime":1311.3,"endTime":1314.96,"body":"So, a little bit"},{"speaker":"Shaun Bagai","startTime":1311.3,"endTime":1314.96,"body":"about how the platform works"},{"speaker":"Shaun Bagai","startTime":1314.96,"endTime":1318.08,"body":"relies on on the anatomy of"},{"speaker":"Shaun Bagai","startTime":1314.96,"endTime":1318.08,"body":"these tumors. When you think of"},{"speaker":"Shaun Bagai","startTime":1318.08,"endTime":1321.5,"body":"tumors, think of a ball of blood"},{"speaker":"Shaun Bagai","startTime":1318.08,"endTime":1321.5,"body":"vessels with tumor cells in"},{"speaker":"Shaun Bagai","startTime":1321.5,"endTime":1324.47,"body":"them. So when you give systemic"},{"speaker":"Shaun Bagai","startTime":1321.5,"endTime":1324.47,"body":"chemotherapy, as much as you get"},{"speaker":"Shaun Bagai","startTime":1324.47,"endTime":1327.47,"body":"all the side effects as it"},{"speaker":"Shaun Bagai","startTime":1324.47,"endTime":1327.47,"body":"circulates the body, blood"},{"speaker":"Shaun Bagai","startTime":1327.47,"endTime":1330.71,"body":"eventually carries the drugs"},{"speaker":"Shaun Bagai","startTime":1327.47,"endTime":1330.71,"body":"into the tumor. There are many"},{"speaker":"Shaun Bagai","startTime":1330.71,"endTime":1333.98,"body":"tumors in the body that don't"},{"speaker":"Shaun Bagai","startTime":1330.71,"endTime":1333.98,"body":"have this high level of blood"},{"speaker":"Shaun Bagai","startTime":1334.025,"endTime":1337.505,"body":"supply, don't have large blood"},{"speaker":"Shaun Bagai","startTime":1334.025,"endTime":1337.505,"body":"vessels that connect to the main"},{"speaker":"Shaun Bagai","startTime":1337.505,"endTime":1341.375,"body":"circulation, and if you think"},{"speaker":"Shaun Bagai","startTime":1337.505,"endTime":1341.375,"body":"about it, think of a city next"},{"speaker":"Shaun Bagai","startTime":1341.375,"endTime":1344.345,"body":"to a freeway with no off ramps,"},{"speaker":"Shaun Bagai","startTime":1341.375,"endTime":1344.345,"body":"a lot of tumors behave that way,"},{"speaker":"Shaun Bagai","startTime":1344.345,"endTime":1347.225,"body":"like pancreatic cancer, where we"},{"speaker":"Shaun Bagai","startTime":1344.345,"endTime":1347.225,"body":"have the bulk of our experience."},{"speaker":"Shaun Bagai","startTime":1347.225,"endTime":1349.745,"body":"And without that off ramp,"},{"speaker":"Shaun Bagai","startTime":1347.225,"endTime":1349.745,"body":"there's no way for the therapy"},{"speaker":"Shaun Bagai","startTime":1349.745,"endTime":1352.745,"body":"to get to the tumor. Our"},{"speaker":"Shaun Bagai","startTime":1349.745,"endTime":1352.745,"body":"technology works in a manner"},{"speaker":"Shaun Bagai","startTime":1352.745,"endTime":1356.375,"body":"where it's a small catheter, a"},{"speaker":"Shaun Bagai","startTime":1352.745,"endTime":1356.375,"body":"plastic tube, that a physician"},{"speaker":"Shaun Bagai","startTime":1356.375,"endTime":1360.35,"body":"inserts under X-ray guidance"},{"speaker":"Shaun Bagai","startTime":1356.375,"endTime":1360.35,"body":"through a very small incision in"},{"speaker":"Shaun Bagai","startTime":1360.35,"endTime":1363.23,"body":"the leg, which is a couple"},{"speaker":"Shaun Bagai","startTime":1360.35,"endTime":1363.23,"body":"millimeters, and they place our"},{"speaker":"Shaun Bagai","startTime":1363.23,"endTime":1366.86,"body":"device, the Renovocath, adjacent"},{"speaker":"Shaun Bagai","startTime":1363.23,"endTime":1366.86,"body":"to the tumor, and it pushes"},{"speaker":"Shaun Bagai","startTime":1366.86,"endTime":1370.94,"body":"drugs across the wall of the"},{"speaker":"Shaun Bagai","startTime":1366.86,"endTime":1370.94,"body":"blood vessel to saturate the"},{"speaker":"Shaun Bagai","startTime":1370.94,"endTime":1374.69,"body":"chemotherapy in the tumor area"},{"speaker":"Shaun Bagai","startTime":1370.94,"endTime":1374.69,"body":"for 20 minutes at a time. So"},{"speaker":"Shaun Bagai","startTime":1374.69,"endTime":1377.69,"body":"again, think about the freeway"},{"speaker":"Shaun Bagai","startTime":1374.69,"endTime":1377.69,"body":"analogy: is we're creating these"},{"speaker":"Shaun Bagai","startTime":1377.69,"endTime":1381.215,"body":"little channels from the freeway"},{"speaker":"Shaun Bagai","startTime":1377.69,"endTime":1381.215,"body":"to get into the city, and with"},{"speaker":"Shaun Bagai","startTime":1381.215,"endTime":1385.385,"body":"this, we can bathe the tumor in"},{"speaker":"Shaun Bagai","startTime":1381.215,"endTime":1385.385,"body":"chemotherapy. You get almost 100"},{"speaker":"Shaun Bagai","startTime":1385.385,"endTime":1389.315,"body":"times concentration of"},{"speaker":"Shaun Bagai","startTime":1385.385,"endTime":1389.315,"body":"chemotherapy at the tissue site"},{"speaker":"Shaun Bagai","startTime":1389.315,"endTime":1392.195,"body":"than you would if you gave it"},{"speaker":"Shaun Bagai","startTime":1389.315,"endTime":1392.195,"body":"systemically, which both reduces"},{"speaker":"Shaun Bagai","startTime":1392.195,"endTime":1394.415,"body":"the systemic toxicities, of"},{"speaker":"Shaun Bagai","startTime":1392.195,"endTime":1394.415,"body":"course, because it's not"},{"speaker":"Shaun Bagai","startTime":1394.415,"endTime":1397.025,"body":"circulating the whole body the"},{"speaker":"Shaun Bagai","startTime":1394.415,"endTime":1397.025,"body":"entire time, and then you get"},{"speaker":"Shaun Bagai","startTime":1397.025,"endTime":1399.155,"body":"very high doses in the tumor"},{"speaker":"Shaun Bagai","startTime":1397.025,"endTime":1399.155,"body":"itself."},{"speaker":"John Simboli","startTime":1399.35,"endTime":1401.11,"body":"I'm sure you get"},{"speaker":"John Simboli","startTime":1399.35,"endTime":1401.11,"body":"this question at investor"},{"speaker":"John Simboli","startTime":1401.23,"endTime":1403.9,"body":"conferences and in other"},{"speaker":"John Simboli","startTime":1401.23,"endTime":1403.9,"body":"situations, like if this is such"},{"speaker":"John Simboli","startTime":1403.96,"endTime":1406.24,"body":"a good idea, how come nobody"},{"speaker":"John Simboli","startTime":1403.96,"endTime":1406.24,"body":"else thought of it?"},{"speaker":"Shaun Bagai","startTime":1406.39,"endTime":1408.04,"body":"It's one of those"},{"speaker":"Shaun Bagai","startTime":1406.39,"endTime":1408.04,"body":"ideas where I've been to"},{"speaker":"Shaun Bagai","startTime":1408.04,"endTime":1410.89,"body":"conferences many years ago,"},{"speaker":"Shaun Bagai","startTime":1408.04,"endTime":1410.89,"body":"early on with this company, and"},{"speaker":"Shaun Bagai","startTime":1410.89,"endTime":1413.62,"body":"a doctor said, \"Yeah, why didn't"},{"speaker":"Shaun Bagai","startTime":1410.89,"endTime":1413.62,"body":"I think of that? It's this. This"},{"speaker":"Shaun Bagai","startTime":1413.62,"endTime":1417.46,"body":"is so simple. It's so eloquent.\""},{"speaker":"Shaun Bagai","startTime":1413.62,"endTime":1417.46,"body":"And and the reason is because"},{"speaker":"Shaun Bagai","startTime":1417.46,"endTime":1420.34,"body":"this pathway of going across the"},{"speaker":"Shaun Bagai","startTime":1417.46,"endTime":1420.34,"body":"vessel wall had never been"},{"speaker":"Shaun Bagai","startTime":1420.34,"endTime":1424.75,"body":"discovered, and as much as when"},{"speaker":"Shaun Bagai","startTime":1420.34,"endTime":1424.75,"body":"you're successful and you look"},{"speaker":"Shaun Bagai","startTime":1424.75,"endTime":1427.75,"body":"back, you look like geniuses. We"},{"speaker":"Shaun Bagai","startTime":1424.75,"endTime":1427.75,"body":"get lucky along the way, and I"},{"speaker":"Shaun Bagai","startTime":1427.75,"endTime":1429.955,"body":"look back to one of our first"},{"speaker":"Shaun Bagai","startTime":1427.75,"endTime":1429.955,"body":"patients where we made this"},{"speaker":"Shaun Bagai","startTime":1429.955,"endTime":1433.135,"body":"discovery. We thought we're"},{"speaker":"Shaun Bagai","startTime":1429.955,"endTime":1433.135,"body":"isolating flow to little tumor"},{"speaker":"Shaun Bagai","startTime":1433.135,"endTime":1435.745,"body":"feeders, little blood vessels"},{"speaker":"Shaun Bagai","startTime":1433.135,"endTime":1435.745,"body":"that go to the tumor, and what"},{"speaker":"Shaun Bagai","startTime":1435.745,"endTime":1439.645,"body":"we quickly realized is it wasn't"},{"speaker":"Shaun Bagai","startTime":1435.745,"endTime":1439.645,"body":"little tumor feeders. We needed"},{"speaker":"Shaun Bagai","startTime":1439.645,"endTime":1442.945,"body":"to put the device in a manner"},{"speaker":"Shaun Bagai","startTime":1439.645,"endTime":1442.945,"body":"where there's no escape routes"},{"speaker":"Shaun Bagai","startTime":1442.945,"endTime":1445.585,"body":"for chemotherapy, and then use"},{"speaker":"Shaun Bagai","startTime":1442.945,"endTime":1445.585,"body":"pressure to force the drug"},{"speaker":"Shaun Bagai","startTime":1445.585,"endTime":1448.405,"body":"across the vessel wall. So we"},{"speaker":"Shaun Bagai","startTime":1445.585,"endTime":1448.405,"body":"were onto something with"},{"speaker":"Shaun Bagai","startTime":1448.405,"endTime":1451.255,"body":"localized therapy, and along the"},{"speaker":"Shaun Bagai","startTime":1448.405,"endTime":1451.255,"body":"way, we discovered this what we"},{"speaker":"Shaun Bagai","startTime":1451.255,"endTime":1454.81,"body":"call transarterial"},{"speaker":"Shaun Bagai","startTime":1451.255,"endTime":1454.81,"body":"microperfusion or T`AMP, or"},{"speaker":"John Simboli","startTime":1452.41,"endTime":1462.82,"body":"Is there a pattern"},{"speaker":"John Simboli","startTime":1452.41,"endTime":1462.82,"body":"where people look at renovo and"},{"speaker":"John Simboli","startTime":1454.96,"endTime":1458.05,"body":"transarterial being across the"},{"speaker":"John Simboli","startTime":1454.96,"endTime":1458.05,"body":"artery wall, and that's where we"},{"speaker":"John Simboli","startTime":1458.05,"endTime":1460.51,"body":"developed a lot of our patent"},{"speaker":"John Simboli","startTime":1458.05,"endTime":1460.51,"body":"portfolio and developed this"},{"speaker":"John Simboli","startTime":1460.51,"endTime":1464.59,"body":"whole new mechanism of action"},{"speaker":"John Simboli","startTime":1460.51,"endTime":1464.59,"body":"and chemotherapy delivery that"},{"speaker":"John Simboli","startTime":1462.85,"endTime":1472.48,"body":"say, \"Oh, I see what you're up"},{"speaker":"John Simboli","startTime":1462.85,"endTime":1472.48,"body":"to, and then you say, \"Let me"},{"speaker":"John Simboli","startTime":1464.59,"endTime":1466.93,"body":"hadn't been discovered before,"},{"speaker":"John Simboli","startTime":1464.59,"endTime":1466.93,"body":"and now we're developing that."},{"speaker":"John Simboli","startTime":1472.48,"endTime":1474.31,"body":"let me explain a little further"},{"speaker":"John Simboli","startTime":1472.48,"endTime":1474.31,"body":"because we're actually not doing"},{"speaker":"John Simboli","startTime":1474.31,"endTime":1475.03,"body":"that. We're doing this."},{"speaker":"Shaun Bagai","startTime":1475.66,"endTime":1477.76,"body":"When you think of"},{"speaker":"Shaun Bagai","startTime":1475.66,"endTime":1477.76,"body":"chemotherapy, you think of blood"},{"speaker":"Shaun Bagai","startTime":1477.76,"endTime":1480.34,"body":"vessels that take the drugs"},{"speaker":"Shaun Bagai","startTime":1477.76,"endTime":1480.34,"body":"there. If you think about"},{"speaker":"Shaun Bagai","startTime":1480.34,"endTime":1483.4,"body":"pancreatic cancer tumors. You"},{"speaker":"Shaun Bagai","startTime":1480.34,"endTime":1483.4,"body":"think of high pressure, what"},{"speaker":"Shaun Bagai","startTime":1483.4,"endTime":1486.61,"body":"they call desmoplastic barriers"},{"speaker":"Shaun Bagai","startTime":1483.4,"endTime":1486.61,"body":"around the tumor, just"},{"speaker":"Shaun Bagai","startTime":1486.61,"endTime":1490.06,"body":"impenetrable to chemotherapy."},{"speaker":"Shaun Bagai","startTime":1486.61,"endTime":1490.06,"body":"But technically, it's not that"},{"speaker":"Shaun Bagai","startTime":1490.06,"endTime":1492.64,"body":"they're impenetrable. It's just"},{"speaker":"Shaun Bagai","startTime":1490.06,"endTime":1492.64,"body":"there are no pathways to get"},{"speaker":"Shaun Bagai","startTime":1492.64,"endTime":1495.82,"body":"into the tumor, and so"},{"speaker":"Shaun Bagai","startTime":1492.64,"endTime":1495.82,"body":"everyone's always thinking about"},{"speaker":"Shaun Bagai","startTime":1495.82,"endTime":1498.79,"body":"blood flow into tumors, and"},{"speaker":"Shaun Bagai","startTime":1495.82,"endTime":1498.79,"body":"that's how you get there. And"},{"speaker":"Shaun Bagai","startTime":1498.79,"endTime":1501.385,"body":"what we discovered is we're not"},{"speaker":"Shaun Bagai","startTime":1498.79,"endTime":1501.385,"body":"using the blood vessels, we're"},{"speaker":"Shaun Bagai","startTime":1501.385,"endTime":1505.195,"body":"pushing the therapy outside the"},{"speaker":"Shaun Bagai","startTime":1501.385,"endTime":1505.195,"body":"blood vessels in the tissue, and"},{"speaker":"Shaun Bagai","startTime":1505.195,"endTime":1509.335,"body":"it takes even physicians, not"},{"speaker":"Shaun Bagai","startTime":1505.195,"endTime":1509.335,"body":"just investors, sometimes two,"},{"speaker":"Shaun Bagai","startTime":1509.335,"endTime":1512.305,"body":"three, four, five, 10 times to"},{"speaker":"Shaun Bagai","startTime":1509.335,"endTime":1512.305,"body":"understand this is a different"},{"speaker":"Shaun Bagai","startTime":1512.305,"endTime":1514.555,"body":"mechanism of action. It's a"},{"speaker":"Shaun Bagai","startTime":1512.305,"endTime":1514.555,"body":"different way to think about the"},{"speaker":"Shaun Bagai","startTime":1514.555,"endTime":1518.695,"body":"anatomy because it hasn't been"},{"speaker":"Shaun Bagai","startTime":1514.555,"endTime":1518.695,"body":"done before. So it is confusing"},{"speaker":"Shaun Bagai","startTime":1518.695,"endTime":1522.01,"body":"at first because a lot of"},{"speaker":"Shaun Bagai","startTime":1518.695,"endTime":1522.01,"body":"physicians, investors, people in"},{"speaker":"Shaun Bagai","startTime":1522.01,"endTime":1524.68,"body":"general say, \"Oh, that makes"},{"speaker":"Shaun Bagai","startTime":1522.01,"endTime":1524.68,"body":"sense. You're finding the little"},{"speaker":"Shaun Bagai","startTime":1524.68,"endTime":1527.02,"body":"blood vessels to push"},{"speaker":"Shaun Bagai","startTime":1524.68,"endTime":1527.02,"body":"chemotherapy through, and you're"},{"speaker":"Shaun Bagai","startTime":1527.02,"endTime":1529.39,"body":"you're blocking it and"},{"speaker":"Shaun Bagai","startTime":1527.02,"endTime":1529.39,"body":"isolating.\" It's like, no, not"},{"speaker":"Shaun Bagai","startTime":1529.39,"endTime":1532.39,"body":"quite. But we're going outside"},{"speaker":"Shaun Bagai","startTime":1529.39,"endTime":1532.39,"body":"the blood vessels, and that once"},{"speaker":"Shaun Bagai","startTime":1532.39,"endTime":1536.41,"body":"people start to click on that"},{"speaker":"Shaun Bagai","startTime":1532.39,"endTime":1536.41,"body":"piece of the anatomy, it starts"},{"speaker":"Shaun Bagai","startTime":1536.41,"endTime":1539.83,"body":"to look at how we're doing this."},{"speaker":"Shaun Bagai","startTime":1536.41,"endTime":1539.83,"body":"It makes sense that this is"},{"speaker":"Shaun Bagai","startTime":1539.83,"endTime":1541.54,"body":"something we've never seen"},{"speaker":"Shaun Bagai","startTime":1539.83,"endTime":1541.54,"body":"before."},{"speaker":"John Simboli","startTime":1541.54,"endTime":1544.405,"body":"Do you get the"},{"speaker":"John Simboli","startTime":1541.54,"endTime":1544.405,"body":"question of, well, are you a"},{"speaker":"John Simboli","startTime":1544.405,"endTime":1547.045,"body":"device company? Are you a"},{"speaker":"John Simboli","startTime":1544.405,"endTime":1547.045,"body":"therapeutics company? Are you"},{"speaker":"John Simboli","startTime":1547.045,"endTime":1549.985,"body":"both? And then how do you work"},{"speaker":"John Simboli","startTime":1547.045,"endTime":1549.985,"body":"through that?"},{"speaker":"Shaun Bagai","startTime":1549.76,"endTime":1552.285,"body":"That's actually one"},{"speaker":"Shaun Bagai","startTime":1549.76,"endTime":1552.285,"body":"of the tougher for investor"},{"speaker":"Shaun Bagai","startTime":1552.339,"endTime":1555.617,"body":"questions I have because a lot"},{"speaker":"Shaun Bagai","startTime":1552.339,"endTime":1555.617,"body":"of institutional investors and"},{"speaker":"Shaun Bagai","startTime":1555.671,"endTime":1558.734,"body":"analysts put you in a bucket."},{"speaker":"Shaun Bagai","startTime":1555.671,"endTime":1558.734,"body":"It's either you're a device"},{"speaker":"Shaun Bagai","startTime":1558.788,"endTime":1562.012,"body":"company, medical technology, or"},{"speaker":"Shaun Bagai","startTime":1558.788,"endTime":1562.012,"body":"you're a pharma company, the"},{"speaker":"Shaun Bagai","startTime":1562.066,"endTime":1565.344,"body":"biotech side, and so being both"},{"speaker":"Shaun Bagai","startTime":1562.066,"endTime":1565.344,"body":"is very confusing to a lot of"},{"speaker":"Shaun Bagai","startTime":1565.398,"endTime":1568.568,"body":"people. On the flip side, and"},{"speaker":"Shaun Bagai","startTime":1565.398,"endTime":1568.568,"body":"this is where savvy investors"},{"speaker":"Shaun Bagai","startTime":1568.622,"endTime":1571.9,"body":"who see the disconnect in our"},{"speaker":"Shaun Bagai","startTime":1568.622,"endTime":1571.9,"body":"valuation where we're going see"},{"speaker":"Shaun Bagai","startTime":1571.954,"endTime":1575.071,"body":"the commercial opportunity of"},{"speaker":"Shaun Bagai","startTime":1571.954,"endTime":1575.071,"body":"the device being a multi-100"},{"speaker":"Shaun Bagai","startTime":1575.125,"endTime":1578.134,"body":"million dollar business"},{"speaker":"Shaun Bagai","startTime":1575.125,"endTime":1578.134,"body":"opportunity that we're embarking"},{"speaker":"Shaun Bagai","startTime":1578.188,"endTime":1581.466,"body":"on now. And oh yeah, by the way,"},{"speaker":"Shaun Bagai","startTime":1578.188,"endTime":1581.466,"body":"in the background, we've got"},{"speaker":"Shaun Bagai","startTime":1581.52,"endTime":1584.69,"body":"this phase three therapeutic"},{"speaker":"Shaun Bagai","startTime":1581.52,"endTime":1584.69,"body":"clinical trial using that same"},{"speaker":"Shaun Bagai","startTime":1584.744,"endTime":1588.56,"body":"device in combination that could"},{"speaker":"Shaun Bagai","startTime":1584.744,"endTime":1588.56,"body":"be a multi-billion-dollar opportunity."},{"speaker":"John Simboli","startTime":1588.61,"endTime":1590.23,"body":"When you think"},{"speaker":"John Simboli","startTime":1588.61,"endTime":1590.23,"body":"about the pipeline and how it's"},{"speaker":"John Simboli","startTime":1590.26,"endTime":1592.69,"body":"an expression of your vision for"},{"speaker":"John Simboli","startTime":1590.26,"endTime":1592.69,"body":"the company, can you take me"},{"speaker":"John Simboli","startTime":1592.81,"endTime":1597.22,"body":"down the paths of, you know, the"},{"speaker":"John Simboli","startTime":1592.81,"endTime":1597.22,"body":"device itself, how it's used in"},{"speaker":"John Simboli","startTime":1597.46,"endTime":1598.36,"body":"combination of the therapy?"},{"speaker":"Shaun Bagai","startTime":1599.0,"endTime":1601.64,"body":"So the initial"},{"speaker":"Shaun Bagai","startTime":1599.0,"endTime":1601.64,"body":"inception of this device"},{"speaker":"Shaun Bagai","startTime":1601.64,"endTime":1604.4,"body":"technology came from the"},{"speaker":"Shaun Bagai","startTime":1601.64,"endTime":1604.4,"body":"founder, Dr. Ramtin Agah, where"},{"speaker":"Shaun Bagai","startTime":1604.4,"endTime":1608.06,"body":"he saw a need in the pancreas"},{"speaker":"Shaun Bagai","startTime":1604.4,"endTime":1608.06,"body":"specifically. So this was"},{"speaker":"Shaun Bagai","startTime":1608.06,"endTime":1610.46,"body":"actually designed initially for"},{"speaker":"Shaun Bagai","startTime":1608.06,"endTime":1610.46,"body":"pancreatic treatment of some"},{"speaker":"Shaun Bagai","startTime":1610.46,"endTime":1614.33,"body":"kind. Chemotherapy is where"},{"speaker":"Shaun Bagai","startTime":1610.46,"endTime":1614.33,"body":"we've taken it for pancreatic"},{"speaker":"Shaun Bagai","startTime":1614.33,"endTime":1617.3,"body":"cancer treatment. From a"},{"speaker":"Shaun Bagai","startTime":1614.33,"endTime":1617.3,"body":"pipeline perspective, we've been"},{"speaker":"Shaun Bagai","startTime":1617.3,"endTime":1621.14,"body":"using in our clinical trials a"},{"speaker":"Shaun Bagai","startTime":1617.3,"endTime":1621.14,"body":"drug called gemcitabine. It's"},{"speaker":"Shaun Bagai","startTime":1621.14,"endTime":1624.125,"body":"been around for decades. It's"},{"speaker":"Shaun Bagai","startTime":1621.14,"endTime":1624.125,"body":"generic. Our drug device"},{"speaker":"Shaun Bagai","startTime":1624.125,"endTime":1626.795,"body":"combination in a phase three"},{"speaker":"Shaun Bagai","startTime":1624.125,"endTime":1626.795,"body":"trial is with this combination"},{"speaker":"Shaun Bagai","startTime":1626.795,"endTime":1631.145,"body":"or device, the Renovocath plus"},{"speaker":"Shaun Bagai","startTime":1626.795,"endTime":1631.145,"body":"this specific drug. From a"},{"speaker":"Shaun Bagai","startTime":1631.145,"endTime":1634.415,"body":"pipeline perspective, what's"},{"speaker":"Shaun Bagai","startTime":1631.145,"endTime":1634.415,"body":"amazing about the technology is"},{"speaker":"Shaun Bagai","startTime":1634.415,"endTime":1637.985,"body":"this is a platform. It could be"},{"speaker":"Shaun Bagai","startTime":1634.415,"endTime":1637.985,"body":"used with, I'd say, any drug or"},{"speaker":"Shaun Bagai","startTime":1637.985,"endTime":1640.715,"body":"agent, and it could be delivered"},{"speaker":"Shaun Bagai","startTime":1637.985,"endTime":1640.715,"body":"to almost any tumor next to a"},{"speaker":"Shaun Bagai","startTime":1640.715,"endTime":1644.615,"body":"blood vessel. We've been hyper"},{"speaker":"Shaun Bagai","startTime":1640.715,"endTime":1644.615,"body":"focused to show success in inone"},{"speaker":"Shaun Bagai","startTime":1644.615,"endTime":1648.02,"body":"of the most challenging tumors"},{"speaker":"Shaun Bagai","startTime":1644.615,"endTime":1648.02,"body":"of all times, pancreatic cancer."},{"speaker":"Shaun Bagai","startTime":1648.02,"endTime":1650.57,"body":"And with that, we can then apply"},{"speaker":"Shaun Bagai","startTime":1648.02,"endTime":1650.57,"body":"this. Okay, let's look at"},{"speaker":"Shaun Bagai","startTime":1650.57,"endTime":1653.48,"body":"different drugs, maybe"},{"speaker":"Shaun Bagai","startTime":1650.57,"endTime":1653.48,"body":"immunotherapeutics, cells,"},{"speaker":"Shaun Bagai","startTime":1653.48,"endTime":1656.54,"body":"agents, antibodies, oncolytic"},{"speaker":"Shaun Bagai","startTime":1653.48,"endTime":1656.54,"body":"viruses. So there's a whole"},{"speaker":"Shaun Bagai","startTime":1656.54,"endTime":1658.73,"body":"platform that we could develop"},{"speaker":"Shaun Bagai","startTime":1656.54,"endTime":1658.73,"body":"in terms of drug device"},{"speaker":"Shaun Bagai","startTime":1658.73,"endTime":1661.64,"body":"combinations. And beyond"},{"speaker":"Shaun Bagai","startTime":1658.73,"endTime":1661.64,"body":"pancreatic cancers, there are"},{"speaker":"Shaun Bagai","startTime":1661.64,"endTime":1664.07,"body":"other tumors in the body that"},{"speaker":"Shaun Bagai","startTime":1661.64,"endTime":1664.07,"body":"behave very similarly to"},{"speaker":"Shaun Bagai","startTime":1664.07,"endTime":1666.77,"body":"pancreatic cancer, and either"},{"speaker":"Shaun Bagai","startTime":1664.07,"endTime":1666.77,"body":"other tumors that are a little"},{"speaker":"Shaun Bagai","startTime":1666.77,"endTime":1669.785,"body":"bit different, where they could"},{"speaker":"Shaun Bagai","startTime":1666.77,"endTime":1669.785,"body":"benefit from localized kind of"},{"speaker":"Shaun Bagai","startTime":1669.785,"endTime":1673.445,"body":"isolated treatment. So, from a"},{"speaker":"Shaun Bagai","startTime":1669.785,"endTime":1673.445,"body":"pipeline perspective, I see both"},{"speaker":"Shaun Bagai","startTime":1673.445,"endTime":1675.605,"body":"sides, and this goes back to"},{"speaker":"Shaun Bagai","startTime":1673.445,"endTime":1675.605,"body":"your question about pharma"},{"speaker":"Shaun Bagai","startTime":1675.605,"endTime":1678.635,"body":"versus device. On the device"},{"speaker":"Shaun Bagai","startTime":1675.605,"endTime":1678.635,"body":"side, this device, this"},{"speaker":"Shaun Bagai","startTime":1678.635,"endTime":1680.795,"body":"platform, can be used with"},{"speaker":"Shaun Bagai","startTime":1678.635,"endTime":1680.795,"body":"almost any agent. It's a"},{"speaker":"Shaun Bagai","startTime":1680.795,"endTime":1684.575,"body":"delivery system for almost any"},{"speaker":"Shaun Bagai","startTime":1680.795,"endTime":1684.575,"body":"tumor, and then on the pharma"},{"speaker":"Shaun Bagai","startTime":1684.575,"endTime":1687.785,"body":"biotech side, and we talk to"},{"speaker":"Shaun Bagai","startTime":1684.575,"endTime":1687.785,"body":"biotech companies on this. Is"},{"speaker":"Shaun Bagai","startTime":1687.785,"endTime":1691.19,"body":"there are partnerships to be had"},{"speaker":"Shaun Bagai","startTime":1687.785,"endTime":1691.19,"body":"on let's explore taking out the"},{"speaker":"Shaun Bagai","startTime":1691.19,"endTime":1694.13,"body":"toxicity profile of your drug by"},{"speaker":"Shaun Bagai","startTime":1691.19,"endTime":1694.13,"body":"localizing the therapy because"},{"speaker":"Shaun Bagai","startTime":1694.13,"endTime":1697.19,"body":"we have the best in class"},{"speaker":"Shaun Bagai","startTime":1694.13,"endTime":1697.19,"body":"platform to deliver local"},{"speaker":"Shaun Bagai","startTime":1697.19,"endTime":1699.65,"body":"therapy in a mechanism that"},{"speaker":"Shaun Bagai","startTime":1697.19,"endTime":1699.65,"body":"hasn't been seen before."},{"speaker":"Shaun Bagai","startTime":1699.63,"endTime":1702.27,"body":"There are several tumor types"},{"speaker":"Shaun Bagai","startTime":1699.63,"endTime":1702.27,"body":"and classes of drugs that would"},{"speaker":"Shaun Bagai","startTime":1702.27,"endTime":1705.72,"body":"make sense to go next, and we're"},{"speaker":"Shaun Bagai","startTime":1702.27,"endTime":1705.72,"body":"exploring several of those now."},{"speaker":"Shaun Bagai","startTime":1705.72,"endTime":1709.26,"body":"We got FDA clearance for the"},{"speaker":"Shaun Bagai","startTime":1705.72,"endTime":1709.26,"body":"device component back in 2014,"},{"speaker":"Shaun Bagai","startTime":1709.68,"endTime":1712.32,"body":"but this goes back to my early"},{"speaker":"Shaun Bagai","startTime":1709.68,"endTime":1712.32,"body":"roots when I talked about"},{"speaker":"Shaun Bagai","startTime":1712.32,"endTime":1715.53,"body":"physician adoption and changing"},{"speaker":"Shaun Bagai","startTime":1712.32,"endTime":1715.53,"body":"physician behavior. We"},{"speaker":"Shaun Bagai","startTime":1715.53,"endTime":1718.56,"body":"recognized right off the bat"},{"speaker":"Shaun Bagai","startTime":1715.53,"endTime":1718.56,"body":"we're not going to have this"},{"speaker":"Shaun Bagai","startTime":1718.56,"endTime":1721.95,"body":"device or product used unless"},{"speaker":"Shaun Bagai","startTime":1718.56,"endTime":1721.95,"body":"you have data to demonstrate"},{"speaker":"Shaun Bagai","startTime":1721.95,"endTime":1723.915,"body":"that what you're doing is"},{"speaker":"Shaun Bagai","startTime":1721.95,"endTime":1723.915,"body":"actually has the potential to"},{"speaker":"Shaun Bagai","startTime":1723.915,"endTime":1726.525,"body":"work. So instead of"},{"speaker":"Shaun Bagai","startTime":1723.915,"endTime":1726.525,"body":"commercializing the product, we"},{"speaker":"Shaun Bagai","startTime":1726.525,"endTime":1729.795,"body":"went directly into clinical"},{"speaker":"Shaun Bagai","startTime":1726.525,"endTime":1729.795,"body":"trials with the approved device."},{"speaker":"Shaun Bagai","startTime":1729.795,"endTime":1733.995,"body":"So our phase one, two trials,"},{"speaker":"Shaun Bagai","startTime":1729.795,"endTime":1733.995,"body":"now the phase three trial has"},{"speaker":"Shaun Bagai","startTime":1733.995,"endTime":1737.055,"body":"all been using this approved"},{"speaker":"Shaun Bagai","startTime":1733.995,"endTime":1737.055,"body":"medical device. It's more"},{"speaker":"Shaun Bagai","startTime":1737.055,"endTime":1739.815,"body":"recently where physicians are"},{"speaker":"Shaun Bagai","startTime":1737.055,"endTime":1739.815,"body":"seeing the benefit in patients."},{"speaker":"Shaun Bagai","startTime":1739.815,"endTime":1742.935,"body":"They're seeing the early data,"},{"speaker":"Shaun Bagai","startTime":1739.815,"endTime":1742.935,"body":"and they're saying, \"Look, this"},{"speaker":"Shaun Bagai","startTime":1742.935,"endTime":1745.98,"body":"device is cleared. I want it"},{"speaker":"Shaun Bagai","startTime":1742.935,"endTime":1745.98,"body":"today to treat patients because"},{"speaker":"Shaun Bagai","startTime":1745.98,"endTime":1749.19,"body":"we need this.\" That pushed us to"},{"speaker":"Shaun Bagai","startTime":1745.98,"endTime":1749.19,"body":"commercialize the product last"},{"speaker":"Shaun Bagai","startTime":1749.19,"endTime":1753.21,"body":"year. And when I say use it now"},{"speaker":"Shaun Bagai","startTime":1749.19,"endTime":1753.21,"body":"commercially, as I mentioned, we"},{"speaker":"Shaun Bagai","startTime":1753.21,"endTime":1756.57,"body":"are in several clinical trials"},{"speaker":"Shaun Bagai","startTime":1753.21,"endTime":1756.57,"body":"earlier. The phase three that we"},{"speaker":"Shaun Bagai","startTime":1756.57,"endTime":1760.38,"body":"have ongoing is a drug device"},{"speaker":"Shaun Bagai","startTime":1756.57,"endTime":1760.38,"body":"combination, pretty much like a"},{"speaker":"Shaun Bagai","startTime":1760.38,"endTime":1763.17,"body":"therapeutic study. It's run by"},{"speaker":"Shaun Bagai","startTime":1760.38,"endTime":1763.17,"body":"the Drug Division of the FDA."},{"speaker":"Shaun Bagai","startTime":1763.17,"endTime":1766.62,"body":"It's for the combination therapy"},{"speaker":"Shaun Bagai","startTime":1763.17,"endTime":1766.62,"body":"of this approved medical device"},{"speaker":"Shaun Bagai","startTime":1766.62,"endTime":1769.905,"body":"through RenovoCath and the"},{"speaker":"Shaun Bagai","startTime":1766.62,"endTime":1769.905,"body":"combination products using a"},{"speaker":"Shaun Bagai","startTime":1769.905,"endTime":1773.565,"body":"drug, gemcitabine, in pancreatic"},{"speaker":"Shaun Bagai","startTime":1769.905,"endTime":1773.565,"body":"cancer specifically. So the goal"},{"speaker":"Shaun Bagai","startTime":1773.565,"endTime":1776.565,"body":"of that study is to demonstrate"},{"speaker":"Shaun Bagai","startTime":1773.565,"endTime":1776.565,"body":"safety and efficacy of that"},{"speaker":"Shaun Bagai","startTime":1776.565,"endTime":1779.415,"body":"combination specifically for"},{"speaker":"Shaun Bagai","startTime":1776.565,"endTime":1779.415,"body":"locally advanced pancreatic"},{"speaker":"Shaun Bagai","startTime":1779.415,"endTime":1782.085,"body":"cancer. So that's where we have"},{"speaker":"Shaun Bagai","startTime":1779.415,"endTime":1782.085,"body":"this dual-pronged approach to"},{"speaker":"Shaun Bagai","startTime":1782.085,"endTime":1784.875,"body":"our business, where we have a"},{"speaker":"Shaun Bagai","startTime":1782.085,"endTime":1784.875,"body":"device business in sales. We"},{"speaker":"Shaun Bagai","startTime":1784.875,"endTime":1788.715,"body":"have a therapeutic business"},{"speaker":"Shaun Bagai","startTime":1784.875,"endTime":1788.715,"body":"that's on the horizon, nearing"},{"speaker":"Shaun Bagai","startTime":1788.715,"endTime":1791.67,"body":"completion of our phase three"},{"speaker":"Shaun Bagai","startTime":1788.715,"endTime":1791.67,"body":"study. One of the reasons why"},{"speaker":"Shaun Bagai","startTime":1791.67,"endTime":1795.39,"body":"we've been able to build and run"},{"speaker":"Shaun Bagai","startTime":1791.67,"endTime":1795.39,"body":"this business much more frugally"},{"speaker":"Shaun Bagai","startTime":1795.39,"endTime":1799.68,"body":"than most companies is that we"},{"speaker":"Shaun Bagai","startTime":1795.39,"endTime":1799.68,"body":"have been receiving compensation"},{"speaker":"Shaun Bagai","startTime":1799.68,"endTime":1803.31,"body":"for the device because it is FDA"},{"speaker":"Shaun Bagai","startTime":1799.68,"endTime":1803.31,"body":"cleared and reimbursed, and now"},{"speaker":"Shaun Bagai","startTime":1803.31,"endTime":1806.64,"body":"with with increase in"},{"speaker":"Shaun Bagai","startTime":1803.31,"endTime":1806.64,"body":"reimbursement and more data out"},{"speaker":"Shaun Bagai","startTime":1806.64,"endTime":1810.42,"body":"there, we're seeing adoption and"},{"speaker":"Shaun Bagai","startTime":1806.64,"endTime":1810.42,"body":"driving a commercial operation"},{"speaker":"Shaun Bagai","startTime":1810.42,"endTime":1813.69,"body":"that helps support the financing"},{"speaker":"Shaun Bagai","startTime":1810.42,"endTime":1813.69,"body":"of all our clinical trials and"},{"speaker":"Shaun Bagai","startTime":1813.69,"endTime":1814.275,"body":"studies as well."},{"speaker":"Shaun Bagai","startTime":1814.96,"endTime":1817.24,"body":"This is very different than most"},{"speaker":"Shaun Bagai","startTime":1814.96,"endTime":1817.24,"body":"therapeutic companies, where"},{"speaker":"Shaun Bagai","startTime":1817.24,"endTime":1821.47,"body":"it's a cash burn for decades"},{"speaker":"Shaun Bagai","startTime":1817.24,"endTime":1821.47,"body":"until there's a potential"},{"speaker":"Shaun Bagai","startTime":1821.47,"endTime":1825.46,"body":"windfall at the end. We're now"},{"speaker":"Shaun Bagai","startTime":1821.47,"endTime":1825.46,"body":"able to reduce our burn and"},{"speaker":"Shaun Bagai","startTime":1825.46,"endTime":1827.74,"body":"hopefully get to a point of"},{"speaker":"Shaun Bagai","startTime":1825.46,"endTime":1827.74,"body":"break even or profitability,"},{"speaker":"Shaun Bagai","startTime":1827.74,"endTime":1831.34,"body":"even before the clinical trial"},{"speaker":"Shaun Bagai","startTime":1827.74,"endTime":1831.34,"body":"has a complete readout and we"},{"speaker":"Shaun Bagai","startTime":1831.34,"endTime":1833.68,"body":"get approval for the"},{"speaker":"Shaun Bagai","startTime":1831.34,"endTime":1833.68,"body":"combination. So it's a different"},{"speaker":"Shaun Bagai","startTime":1833.68,"endTime":1835.9,"body":"animal in that sense, and that's"},{"speaker":"Shaun Bagai","startTime":1833.68,"endTime":1835.9,"body":"where the de-risking comes from"},{"speaker":"Shaun Bagai","startTime":1835.9,"endTime":1838.315,"body":"as well. There's a viable,"},{"speaker":"Shaun Bagai","startTime":1835.9,"endTime":1838.315,"body":"established business in place"},{"speaker":"Shaun Bagai","startTime":1838.315,"endTime":1841.735,"body":"without a big cash burn, and we"},{"speaker":"Shaun Bagai","startTime":1838.315,"endTime":1841.735,"body":"found ways along the way to"},{"speaker":"Shaun Bagai","startTime":1841.735,"endTime":1843.655,"body":"always run the business very"},{"speaker":"Shaun Bagai","startTime":1841.735,"endTime":1843.655,"body":"lean."},{"speaker":"John Simboli","startTime":1844.32,"endTime":1847.23,"body":"If the phase three"},{"speaker":"John Simboli","startTime":1844.32,"endTime":1847.23,"body":"clinical trial develops in the"},{"speaker":"John Simboli","startTime":1847.23,"endTime":1851.07,"body":"way you hope, and any other data"},{"speaker":"John Simboli","startTime":1847.23,"endTime":1851.07,"body":"readouts that you need, and"},{"speaker":"John Simboli","startTime":1851.07,"endTime":1853.47,"body":"things progress, and the FDA"},{"speaker":"John Simboli","startTime":1851.07,"endTime":1853.47,"body":"approves the combination"},{"speaker":"John Simboli","startTime":1853.47,"endTime":1857.1,"body":"someday, if all those things,"},{"speaker":"John Simboli","startTime":1853.47,"endTime":1857.1,"body":"your dream is realized, if it's"},{"speaker":"John Simboli","startTime":1857.1,"endTime":1859.8,"body":"successful, how will the"},{"speaker":"John Simboli","startTime":1857.1,"endTime":1859.8,"body":"day-to-day life of a patient"},{"speaker":"John Simboli","startTime":1859.8,"endTime":1863.13,"body":"treated it in this way, how"},{"speaker":"John Simboli","startTime":1859.8,"endTime":1863.13,"body":"would it change compared to now?"},{"speaker":"Shaun Bagai","startTime":1863.0,"endTime":1865.28,"body":"What we're seeing"},{"speaker":"Shaun Bagai","startTime":1863.0,"endTime":1865.28,"body":"in a lot of our patients, and I"},{"speaker":"Shaun Bagai","startTime":1865.28,"endTime":1868.94,"body":"go back to the the clinical news"},{"speaker":"Shaun Bagai","startTime":1865.28,"endTime":1868.94,"body":"section in our investor website."},{"speaker":"Shaun Bagai","startTime":1868.94,"endTime":1872.42,"body":"We had patients say that I'm"},{"speaker":"Shaun Bagai","startTime":1868.94,"endTime":1872.42,"body":"building my kitchen again. I'm"},{"speaker":"Shaun Bagai","startTime":1872.42,"endTime":1874.7,"body":"bicycle riding with my"},{"speaker":"Shaun Bagai","startTime":1872.42,"endTime":1874.7,"body":"grandkids. I'm going out to"},{"speaker":"Shaun Bagai","startTime":1874.7,"endTime":1877.76,"body":"dinner with my family. These"},{"speaker":"Shaun Bagai","startTime":1874.7,"endTime":1877.76,"body":"aren't things that chemotherapy"},{"speaker":"Shaun Bagai","startTime":1877.76,"endTime":1881.24,"body":"patients don't really say that"},{"speaker":"Shaun Bagai","startTime":1877.76,"endTime":1881.24,"body":"much. So it's great to see that"},{"speaker":"Shaun Bagai","startTime":1881.24,"endTime":1884.78,"body":"the day-to-day lives of a lot of"},{"speaker":"Shaun Bagai","startTime":1881.24,"endTime":1884.78,"body":"our patients seem largely"},{"speaker":"Shaun Bagai","startTime":1884.78,"endTime":1887.09,"body":"unaffected, especially if"},{"speaker":"Shaun Bagai","startTime":1884.78,"endTime":1887.09,"body":"they've had upfront systemic"},{"speaker":"Shaun Bagai","startTime":1887.135,"endTime":1889.685,"body":"chemotherapy. So they compare"},{"speaker":"Shaun Bagai","startTime":1887.135,"endTime":1889.685,"body":"and they share their stories"},{"speaker":"Shaun Bagai","startTime":1889.685,"endTime":1892.955,"body":"about how life was before and"},{"speaker":"Shaun Bagai","startTime":1889.685,"endTime":1892.955,"body":"after RenovaRx."},{"speaker":"John Simboli","startTime":1894.46,"endTime":1895.87,"body":"Sean, thanks for"},{"speaker":"John Simboli","startTime":1894.46,"endTime":1895.87,"body":"speaking with me today."},{"speaker":"Shaun Bagai","startTime":1896.77,"endTime":1898.33,"body":"Thank you, John. It"},{"speaker":"Shaun Bagai","startTime":1896.77,"endTime":1898.33,"body":"was great for the opportunity,"},{"speaker":"Shaun Bagai","startTime":1898.42,"endTime":1901.26,"body":"and I appreciate your questions."},{"speaker":"Shaun Bagai","startTime":1898.42,"endTime":1901.26,"body":"They've really helped explain a"},{"speaker":"Shaun Bagai","startTime":1901.29,"endTime":1903.24,"body":"little bit of my background and"},{"speaker":"Shaun Bagai","startTime":1901.29,"endTime":1903.24,"body":"our great story."},{"speaker":"John Simboli","startTime":1904.0,"endTime":1908.11,"body":"Working alongside"},{"speaker":"John Simboli","startTime":1904.0,"endTime":1908.11,"body":"biopharma founders and CEOs, and"},{"speaker":"John Simboli","startTime":1908.11,"endTime":1911.14,"body":"getting to know their insights"},{"speaker":"John Simboli","startTime":1908.11,"endTime":1911.14,"body":"about leadership through our"},{"speaker":"John Simboli","startTime":1911.14,"endTime":1914.95,"body":"conversations on BioBoss, I"},{"speaker":"John Simboli","startTime":1911.14,"endTime":1914.95,"body":"understand there can be many"},{"speaker":"John Simboli","startTime":1914.95,"endTime":1920.53,"body":"pathways to success. My"},{"speaker":"John Simboli","startTime":1914.95,"endTime":1920.53,"body":"discussion with Shaun Bagai, CEO"},{"speaker":"John Simboli","startTime":1920.53,"endTime":1925.84,"body":"at Renovo RX reminds me how"},{"speaker":"John Simboli","startTime":1920.53,"endTime":1925.84,"body":"energizing the journey can be."},{"speaker":"John Simboli","startTime":1925.84,"endTime":1929.575,"body":"Deciding to build a company"},{"speaker":"John Simboli","startTime":1925.84,"endTime":1929.575,"body":"focused on serving patients is a"},{"speaker":"John Simboli","startTime":1929.575,"endTime":1932.935,"body":"worthy goal, but that doesn't"},{"speaker":"John Simboli","startTime":1929.575,"endTime":1932.935,"body":"mean there is a blueprint for"},{"speaker":"John Simboli","startTime":1932.935,"endTime":1937.015,"body":"how to get there. Like several"},{"speaker":"John Simboli","startTime":1932.935,"endTime":1937.015,"body":"founders and CEOs I've spoken"},{"speaker":"John Simboli","startTime":1937.015,"endTime":1940.615,"body":"with, Sean chose to follow both"},{"speaker":"John Simboli","startTime":1937.015,"endTime":1940.615,"body":"his scientific and"},{"speaker":"John Simboli","startTime":1940.615,"endTime":1944.725,"body":"entrepreneurial interests, and"},{"speaker":"John Simboli","startTime":1940.615,"endTime":1944.725,"body":"take what he calls the path less"},{"speaker":"John Simboli","startTime":1944.725,"endTime":1949.675,"body":"traveled, the railroad tracks"},{"speaker":"John Simboli","startTime":1944.725,"endTime":1949.675,"body":"laid out in front of me. In our"},{"speaker":"John Simboli","startTime":1949.675,"endTime":1953.08,"body":"conversation, Sean described the"},{"speaker":"John Simboli","startTime":1949.675,"endTime":1953.08,"body":"satisfaction that comes from"},{"speaker":"John Simboli","startTime":1953.08,"endTime":1957.22,"body":"having a positive effect on the"},{"speaker":"John Simboli","startTime":1953.08,"endTime":1957.22,"body":"life of an individual patient,"},{"speaker":"John Simboli","startTime":1957.22,"endTime":1961.0,"body":"but Sean realized that his"},{"speaker":"John Simboli","startTime":1957.22,"endTime":1961.0,"body":"contribution could take the form"},{"speaker":"John Simboli","startTime":1961.0,"endTime":1964.18,"body":"of pioneering new therapies that"},{"speaker":"John Simboli","startTime":1961.0,"endTime":1964.18,"body":"could change the way cancer is"},{"speaker":"John Simboli","startTime":1964.18,"endTime":1968.95,"body":"treated. Sean shared his"},{"speaker":"John Simboli","startTime":1964.18,"endTime":1968.95,"body":"understanding that leadership is"},{"speaker":"John Simboli","startTime":1968.95,"endTime":1973.18,"body":"a test of the capacity for"},{"speaker":"John Simboli","startTime":1968.95,"endTime":1973.18,"body":"vision, problem solving, and"},{"speaker":"John Simboli","startTime":1973.18,"endTime":1977.815,"body":"resolve. As he said to me, \"I"},{"speaker":"John Simboli","startTime":1973.18,"endTime":1977.815,"body":"love learning, changing,"},{"speaker":"John Simboli","startTime":1977.815,"endTime":1982.735,"body":"pivoting, doing. Big companies"},{"speaker":"John Simboli","startTime":1977.815,"endTime":1982.735,"body":"are good at scaling. We, as"},{"speaker":"John Simboli","startTime":1982.735,"endTime":1987.625,"body":"small companies, are good at"},{"speaker":"John Simboli","startTime":1982.735,"endTime":1987.625,"body":"getting things done fast. The"},{"speaker":"John Simboli","startTime":1987.625,"endTime":1991.585,"body":"ability to balance imagination"},{"speaker":"John Simboli","startTime":1987.625,"endTime":1991.585,"body":"and clarity, vision and"},{"speaker":"John Simboli","startTime":1991.585,"endTime":1996.055,"body":"competence, is a leadership"},{"speaker":"John Simboli","startTime":1991.585,"endTime":1996.055,"body":"skill in its own right. I'm"},{"speaker":"John Simboli","startTime":1996.1,"endTime":1999.4,"body":"thankful to have met biopharma"},{"speaker":"John Simboli","startTime":1996.1,"endTime":1999.4,"body":"founders and CEOs who find their"},{"speaker":"John Simboli","startTime":1999.4,"endTime":2005.19,"body":"way to pursue this symmetry. I'm"},{"speaker":"John Simboli","startTime":1999.4,"endTime":2005.19,"body":"John Simboli. You're listening"},{"speaker":"John Simboli","startTime":2005.55,"endTime":2006.66,"body":"to BioBoss."},{"speaker":"Unknown","startTime":2010.86,"endTime":2013.86,"body":"BioBoss is brought to"},{"speaker":"Unknown","startTime":2010.86,"endTime":2013.86,"body":"you by Wyant Simboli, a"},{"speaker":"Unknown","startTime":2013.95,"endTime":2017.4,"body":"strategic branding firm focused"},{"speaker":"Unknown","startTime":2013.95,"endTime":2017.4,"body":"on helping life sciences"},{"speaker":"Unknown","startTime":2017.52,"endTime":2021.26,"body":"companies advance. We partner"},{"speaker":"Unknown","startTime":2017.52,"endTime":2021.26,"body":"with companies to define their"},{"speaker":"Unknown","startTime":2021.41,"endTime":2025.22,"body":"story, structure their brand,"},{"speaker":"Unknown","startTime":2021.41,"endTime":2025.22,"body":"and inspire their audience."},{"speaker":"Unknown","startTime":2025.91,"endTime":2029.21,"body":"Visit Wyantsimboli.com for more"},{"speaker":"Unknown","startTime":2025.91,"endTime":2029.21,"body":"information."}]}