Derm-it Trotter! Don't Swear About Skincare.
Feeling frustrated or overwhelmed with everything skin? Does the skinformation overload make you want to swear about skincare? Join Dr. Shannon C. Trotter, board certified dermatologist, as she talks with fellow dermatologists and colleagues in skincare to help separate fact from fiction and simplify the world of skin. After listening, you won’t swear about skincare anymore!
Derm-it Trotter! Don't Swear About Skincare.
Joint Effort: CBD and Your Skin
CBD is everywhere, but what does it actually do for your skin? We sit down with Adam Friedman, MD—dermatologist, chair, and translational researcher—to break down the real science. We clear up CBD vs THC confusion, map how the endocannabinoid system works in keratinocytes, sebocytes, immune cells, and nerves, and explain how CBD influences redness, itch, oil production, and inflammation. We also walk through the legal landscape, why cosmetics are the most realistic path forward, and how to spot mislabeling or contamination when choosing products.
Then we get into the data. You’ll hear about research showing CBD can reduce sebum and calm the inflammasome in acne, early evidence for atopic dermatitis and scalp psoriasis, and a controlled human study where topical CBD reduced UVA-induced DNA damage linked to photoaging. We talk through delivery systems like nanotechnology, safety myths, when to avoid CBD, and what a good certificate of analysis should include. If you care about acne control, skin longevity, or smarter routines, this episode gives you a grounded, hype-free guide to CBD in dermatology.
That CBD probably exerts its activity in our skin, and that's what we're focusing on uh skin, hair, and nails, but in other systems. CBD can prevent DNA damage from ultraviolet radiation, which is linked to accelerate skin aging. So, by definition, we should be able to prevent accelerated skin aging. If it says that it's meant to treat a medical condition, that should be a huge red flag because that is not okay. That is a drug claim.
SPEAKER_00:Welcome to Dermot Trotter, Don't Swear About Skin Care, where host Dr. Shannon C. Trotter, a board-certified dermatologist, sits down with fellow dermatologists and skincare experts to separate fact from fiction and simplify skincare. Let's get started.
SPEAKER_01:Welcome to the Dermotrotter Don't Swear About Skin Care podcast. Today I have a great guest. He's a repeat guest on the podcast. He loved it so much, he had to come back. Professor and Chair of Dermatology, Residency Program Director, and Director of Translational Research at the GW at the George Washington University School of Medicine and Health Sciences. I've got Dr. Adam Freeman back with me here today. Welcome to the podcast, Adam.
SPEAKER_03:So just when I thought I got out, you pulled me back in. I gotta use that famous line, right?
SPEAKER_01:Exactly. Exactly. Well, this is something actually Adam wanted to talk to me about. So we'll have to find out what his interest is in talking about CBD and skin. So I think a lot of people out there are thinking, what? You know, is there a purpose for this? And as you know all too well, there is a potential role here for our patients. So I want to get right into the meat of this because a lot of people are thinking, marijuana and skin, that's CBD. How's this really gonna work? Is it really beneficial? And what are the differences? A lot of people, no, that's something that's controlled, or you can get high from it, or what's the difference between that and THC? So we're gonna have you break it down a little bit so people really understand the difference.
SPEAKER_03:Yeah. So let's start with CBD or cannabidiol. It is one of hundreds of cannabinoids found in the cannabis plant. Uh and before we go further, I gotta say it's hilarious that we have learned so much about the human system from an illegal substance, right? Like when in history do you have a drug really changing our perception, our understanding of human biology? And then, of course, at the end of the day, potential targets and translations for therapies that can improve the human condition. So just kind of throw it out there uh a gold star for illicit drugs. Um, but right, so so CBD is one of many. And I think what most people are aware of is THC, because that's the one that gets you high. Uh, I like to say CBD is kind of like the nerdy sibling doing all the homework, you know, doing the biology and the science in the background, not going to the parties where, of course, THC is the one that can be intoxicating, where CBD is not intoxicating. Actually, pure CBD will not make you feel high in any way that THC can. Now, the reason for this is the biology. So we all have endocannabinoid system. Now, that this was all discovered, as I mentioned before, thanks to the study of ingredients from the cannabis plant. But in essence, we have this unique system that is involved in probably every biological process in our bodies. Now, historically, we define two ways that cannabinoids, things from the cannabis plant, and and there are other types of cannabinoids besides the plant-derived ones, and we'll talk about them. Um, but there are two historic ways that this can happen, do something biologically. One is through the CB1 receptor, which is the receptacle in the central nervous system to which THC binds very tightly. And when THC binds to the CB1 receptor, this is what drives euphoria, alter perception, impaired coordination, maybe making bad decisions, who knows? Uh, whereas CBD has actually a very low affinity, actually, barely any affinity for the CB1 versus CB2, which is expressed on immune cells among other cells in our body. Uh, but even then, it's not it doesn't bind super strongly. In fact, we now know that CBD probably exerts its activity in our skin, and that's what we're focusing on uh skin, hair, and nails, but in other systems, uh, through various other receptors. Um, some on, you know, actually even on nerves called vanillanoid receptors, which are a hot area in dermatology. Uh, these receptors have been implicated in certain conditions like rosacea or even an itch and pain. Uh, there are some nuclear receptors, receptors inside our cells called P PARS that regulate how the cell makes itself, wound healing, how hair makes itself. Um, but there's a whole host of different what are called G protein couple receptors that CBD can bind to, which is one of the reasons why it potentially can have so many beneficial effects. However, none of these receivers have anything to do with psychoactive effects, which is why CBD will not create the same type of uh experience that THC can. Um, you know, you mentioned legality. And that I think is a big piece of this. So, one, I think one of the big interests in this area is because anything historically from the cannabis plant was considered illegal. So, of course, if someone says you can't have it, you want it, right? So that allure of like, ooh, it's a cannabis, yeah, it's like right. Like you're like people are like, I'll tell me more. Um, the that the funny thing is that kind of changed recently. So hemp derived cannabidiol, which means it's uh, you know, cannabis with less than 0.3% of Delta 9 THC by dry weight. So you're talking about a part of the plant that is a very low amount of THC under the 2018 Farm Bill is considered federal legal, federally legal. So if you are making a CBD product derived from this piece, it is considered quote unquote legal. Now, if you're pulling CBD from plants with a greater THC concentration or parts of the flower, then it's still considered controlled under federal level, even if your state allows it. So there's state control and federal control oversight. Um, and and we've seen over the years the expansion of medical marijuana in terms of being able to access a dispensary. Um, there are actually fewer states that don't allow it than do nowadays, which is pretty remarkable. But then there's access recreationally in terms of just, you know, buying it wherever. Um, so that does vary from state to state. Um, but the the hard part is that even under that farm bill with hemp-derived CBD, the FDA does not consider CBD to be a legal dietary supplement or a food ingredient. And so when the farm bill went into effect, there was this massive explosion. You probably remember, like everyone and their mother had a C BD product, C BD shampoo, CBD smoothie, CBD elixir of life, you know, like basically thinking like Zoolander, like CBD is the essence of life, and life is CBD. I don't know, some stupid thing like that. Um was that a good Zoolander?
SPEAKER_01:That was excellent. That was impressive. I like that. Yeah.
SPEAKER_03:Like I'll give you blue steel later on in the interview. Um, so you know, the FDA went kind of crazy because and rightfully so, because all these companies like saw the floodgates open and they made all these products, and the FDA issued like over 60 warning letters to companies making drug-like claims or putting CBD in food or gummies that were um easily accessible over the counter. Now, where things are actually pretty kosher, all said and done, is going to be cosmetics. So hemp drive CBD are allowed to be utilized in topical formulations, um, but they do have to follow all the typical safety rules of an over-the-counter cosmeceutical, which falls under the um FDCA. Um, and uh again, if you're making medical claims, then you can certainly get into some trouble. The big issue though, and this has been highlighted in the literature um twice now, in that many of these products will say they have one thing, and it's a total misdirect that many of these products either have more or less CBD than are actually listed. And also many of them will have THC in them, let alone impurities and God knows what else. There have been several case reports of irritant contact dermatitis, um pesticide poisoning from some of these poorly regulated products. So it's been the wild, wild west, which has really undermined the space. And I think we went, we saw like a bell curve of like everyone's super excited. We even published data on like the overall consumer interest and physician interest in learning more. And then it peaked, and then people lost interest because they were frustrated by the lack of quality products that had evidence supporting their use. And so it kind of fell down and it it went off the cliff. And my hope is that we can reinvigorate it with good science, which is some of the work we're doing.
SPEAKER_01:Well, that's exciting because I know a lot of people out there have been interested in your right. When that craze caught on, everyone was looking for CBD this or hemp oil this, and everyone was jumping on the bandwagon. And I think when you talk about the legalities of it, that's really hindered some of the research, why we don't have great studies. And the challenge now, do you feel like with less regulation or more regulation, that'll make it better for research going forward? Like, how are you able to do the research you're trying to do with all the restrictions that surround it?
SPEAKER_03:So, research-wise, it's become easier. So when I first got into the space, uh, which, oh man, when was this? This was before the farm belt. I know that much because um at that time, getting CBD and working within the lab would have been very difficult. So, what we actually started with was actually something called anandamide, which is or AEA, which is an endocannabinoid. So I mentioned that we right now, you and I, we are making endocannabinoids that are binding to these CB1 and CB2 receptors, controlling sensation, inflammation, cell turnover. So AEA, you can literally buy super easily from like Sigma, for example, these, you know, these companies that sell lab grade materials. So that's what I started with when I got interested in the space serendipitously, because one of my residents, you know, shared a paper that she worked on with Vicky Worth at Penn. And I'm like, oh, this is kind of cool. And she made the comment to me well, you can't deliver them topically because they're lipofilth, they like fatty environments, and they're big, so they can't get through the skin. And so you know me. I'm like, ah, challenge accepted. Let's, let's, let's party. Because delivering on deliverables is one of my areas of research using nanotechnology. And so, with that, at that point, we're like, yeah, we can't get access to C BD to do research. Let's do AAA. But now, yes, I think it actually is easier to work with CBD. THC still, that that comes with some challenge. I personally have done no in vitro translational research with THC, but CBD I can actually access pretty easily and work with it in the lab, animal studies, and even in humans with without much um much red tape. So that I think has become a little bit easier.
SPEAKER_01:So folks are out there suffering, you know, with acne, eczema-ish, like what kind of data is out there about how it may help with those conditions? And or do we have at least some preliminary? Do we have some decent studies for any of those conditions to really support some of those claims?
SPEAKER_03:So the answer is yes and no. So from looking at a million mile high view with respect to clinical data, we do have some small studies looking at, for example, there were two studies I can think of off the bat with a CBD gel for whether it be just kind of like a steatotic eczema or like really dry, irritated skin, or even atopic dermatitis using validated scoring tools to monitor change over time. Um, acne, actually, uh, there was a journal of clinical investigation paper. JCI is like one of the top-tier basic science journals looking at CBD and how it potentially could be useful for acne. And what they found was pretty remarkable. So CBD can one inhibit sebum production. We have very few drugs that inhibit sebum production. And two, it really interfered with the kind of maybe the, I would call it the match that sets off the inflammatory cascade that leads to an inflammatory nodule or cystic nodule by interfering with what's called the inflammation, which is a gatekeeper of inflammation that is overactive in the setting of acne. So we had a really nice mechanistic study. There have been several small clinical trials, nothing amazing, but certainly supportive to look into it. Um, psoriasis, it's interesting. So when medical marijuana first came about, and every state would indicate, all right, these are the things you can write a card. A physician could write a card for someone to go to a dispensary to get marijuana or medical cannabis. Um, psoriasis was on there for several states. And there are several studies now. There is one about a 50-person study looking at a CBD shampoo for scalp psoriasis. Um, there have been subsequent studies also looking at this. And from a mechanistic standpoint, it would make sense how CBD or other cannabinoids through binding to their receptors could be anti-inflammatory, or maybe a better way to position it, it's not that it's anti-inflammatory for any of these, but rather it's pro-resolution of inflammation. And that's a very unique concept in dermatology. We're all about blocking a signal, blocking a receptor. We're anti-inflammation. Whereas when CBD binds to its specific receptors, these G protein coupled receptors, it actually turns on a whole bunch of things and turns off a bunch of things. So what's called the resolvin pathway, very appropriately named, when you hit one of these resolving receptors, it actually kind of, it's almost like the maestro, right? It's like, all right, you, you know, you have to be loud over here to kind of cool off inflammation, and you need to now repair over here. So it really orchestrates turning off an inflammatory environment and then signaling for cells to polarize to the type that actually repair, which is much different than blocking a signal and waiting for things to cool up on their own. So I think that cannabinoids, especially CBD, have so much potential as pro-inflammation resoluting factors. Um, it's just we need more clinical data to support that. Even, you know, when we think about androgen alopecia, hair loss, there are preclinical studies showing that it could be useful there. The big things are where, like how much, how do you deliver it, and for how long? I think those are really some of the biggest issues. Um, but for me, I mean, the area that I think is the best studied, and and full disclosure, I'm saying this because it was my study with um one of my mentors, Brian Burman.
SPEAKER_01:It's okay.
SPEAKER_03:It's the best if I did it. Um I am I there's so many different adjectives I could use to describe myself in saying that. I I actually want to hit myself in the face for sounding so pompous. But um, but I am actually really proud of this work because we really worked hard to come up with a protocol uh a clinical trial protocol that could meet muster, that would generate data that we would feel very comfortable with that it was significant, data that we would feel good or not embarrassed about, submitting to the Journal of American Academy of Dermatology. And so this study, which was designed to look at can CBD protect our skin's DNA from the expected injury from UV radiation? So, very simple question, because we know UVA radiation is the flavor of UV radiation that will cause accelerated skin aging, among other things like skin cancer, which we as dermatologists worry about. Um, but it is directly linked to photoaging. And so we want to see if if we blasted someone with three times the amount of UVA radiation that you would get need to even get a burn. And it's hard to burn someone with UVA, truthfully. Could we protect the skin? And we use a couple different measures to say yes or no. Um, we looked at histology. We took pieces of people's skin and looked at histology. We looked at did the skin thicken in response to that injury? Did we see uh nuclear damage? We can stain the nuclei of our skin cells, and then we extracted uh DNA from the tissue to look for what's called the common deletion, which is a mutation that has been well established over the years that results from UVA radiation. And in 50% of subjects, so we had 20 people in the study, 50% did not have this mutation in those who were treated, versus uh, and we used individuals as their own control. So one side got treatment, one side didn't, we didn't know which. The other side uniformly had this mutation. So um, what that tells us is that CBD can prevent DNA damage from ultraviolet radiation, which is linked to accelerate skin aging. So, by definition, we should be able to prevent accelerated skin aging. Um, and I think this was the most detailed study to date in terms of not just looking at someone, but actually taking tissue. And and I mean, it took a year and a half to do all this to really get to the most minimal nanoscale um level to understand how it's behaving.
SPEAKER_01:Well, it's really exciting, you know, because that's where everything's at. You know, a lot of our listeners out there are thinking, you know, the implications beyond even just acne, psoriasis, and there's an anti-aging component here that can be integrated into the skincare routine. Wow, I mean, that has a lot of promise for the future. Everyone's looking for the next best thing. So you may have just found it here with your study with CBT. So the translation is getting this into a product that then shows that benefit, I think, for patients. Is that kind of where it's headed?
SPEAKER_03:Yeah, so um, so the the product we use. So this, so why I was involved in this clinical study is that um working with a company called Minnow Labs, uh, in collaboration with a company that has developed out of a nanotechnology. So nano meaning a billionth of a meter, these invisible little carriers. The idea was, okay, we know CBD does a whole lot, only if it gets where it needs to be, you know, how you deliver something is probably just as, if not more, important than how something works in the living system. So we combined this with a drug delivery system that I developed as a medical student with my father at Albert Sign College of Medicine. So nice little family story tier. Um, so combining you know, quality CBD with a drug delivery system that we know can get through the stratum corneum, the outer layer of the skin, and release things over time, it was a perfect marriage. And so we do have a product on the market that was used in this clinical study. So the purpose of the study was this prove that if you deliver CBD the right way, it can have a benefit, which goes back to the original question about okay, this there was this wild west of products that came out. How do you know it even works? Exactly. Well, you need a clinical trial to prove that it works. And so that was the purpose here was to prove that this particular product called C elements MD does actually have a biological impact.
SPEAKER_01:So somebody's out there thinking, okay, I buy it, CBD has benefit in the skin, I get it's anti inflammatory, potentially I want to use a CBD product. How do you advise patients or the consumer out there because of the lack of research, if they're trying to really pick something up that they think could have benefit? And you're right, too, from the delivery standpoint, if that hasn't really been studied. For that particular product, how do you guide patients in that conversation?
SPEAKER_03:Yeah, I think that's that is probably the million dollar question because you know you walk into probably any major, you know, um uh drug, I call a drugstore. I mean, that's kind of I I probably aging myself, um, you know, like a CVS or Walgreens, and you could probably find you go on Amazon, Adam.
SPEAKER_01:You go on Amazon.
SPEAKER_03:Oh my god, wow. You actually go to a store? Like, what is wrong with you? Um, like, yes, I look at the papers and I want to watch my program at 7 p.m. and I do collect social security apparently. Um, so uh so um a couple things. So uh the practical filters I use and I tell my patients to use is first look for third-party testing. So there's something called a certificate of analysis or COA that is from an independent lab that often will be linked to a QR code or a batch number on the product. And um, I think that one easy thing is if you're looking at a product and it's not clear, reach out to the company, ask for their COA. If they do not give it to you, they don't respond, you have your answer. Um, the other is transparent labeling. So do they put the exact milligrams of CBD per container? Uh clear ingredient list, realistic claims. I think that's true, honestly, for anything. If anything sounds too good to be true, that's over the counter, it has to be. You know, this is this is, you know, when we think about peptides and natural ingredients, nutraceuticals. If something sounds too good, it probably is nothing. Nothing changes the appearance or biology of your skin overnight uh or permanently. So it it is, it is like kind of the concept of Rome. Rome wasn't built overnight. So the claims have to be realistic, and that is true for CBD as well. Um, if it says that it's meant to treat a medical condition, that should be a huge red flag because that is not okay. That is a drug claim. Uh, reputable manufacturer. So does the company follow GMP rules of compliance? Do they have even clinical data? And often if a company has it, they're gonna humble brag about it on their website for sure because they invest and they spend time doing it. Um, does the company have a track record in dermatology? You know, who do they work with? Um, and are they established or are they just a pop-up? They come out of nowhere, which means they could disappear just as easily. Um, and then last but not least, I think the cosmesis of the product, um, you know, certainly trying for yourself. You know, does it rub in easily? Uh, is there information about stability, for example? Um, I think that's also where um, you know, patient reports, you know, um, you know, affirmations, things like that that the company might post online. Or if you're looking online, people have commented about their experiences. I think that could be helpful at all as well. I mean, clearly that's not scientific, but that certainly can help. Uh, but at the end of the day, this should not replace a prescription medication that has been recommended by a dermatologist by another healthcare practitioner. Um, I consider them as adjuncts. And I use this in my own, like me personally, I use uh specifically the nano CBD product I was mentioning in combination with a retinoid, in combination with sunscreen, because this is not meant to replace sunscreen, it's meant to be its best friend to kind of pick up the slack where sunscreen drops the ball in terms of allowing for UV damage, which no sunscreen can block 100%. So I think it's it's about working into a regimen with other things rather than, oh, this is a one-size-fits-all.
SPEAKER_01:And I think it's really good you comment on that because a lot of people are looking for always this natural replacement and just highlighting the fact that that's not always going to be the case. These are nice add-ins, you know, to really enhance your protection. But it does give you, you know, that thought of, you know, coming from, you know, the marijuana plant that can be natural kind of concept. Because I think a lot of people want to know, or they assume natural is always better. And especially for, you know, people that are pregnant, breastfeeding, what would you say to them about using CBD products? Because a lot of people want to know is it safe because it's natural if they're actually pregnant or breastfeeding.
SPEAKER_03:Yeah. So first things first, natural does not equal safe. I'm so glad you brought that up. Um, the way I kind of think about or talk about it is, you know, what happens in nature is chaotic, right? It's imperfect and very often, often synthetic is taking what we understand about nature, lessons learned. I mean, there are many medications that we have that are derived from plants, even from things that insects or certain animals secrete or make, but they are created and designed in a way that every batch is reproducible. That no matter how many times you buy something, it's going to be the same each time. The other thing is when we think about natural and safe, you know, there's some pretty nasty natural things out there. You know, anthrax, uh, actually aflatoxin, which comes from peanuts, is the most toxic substance on the planet. So I think it's important to like push that aside, that it's not all or none, natural versus synthetic. Really, toxicology comes down to concentration, not ingredient concentration. So water is toxic if you have too much of it, because it will dilute all your electrolytes, your brain will swell, and you'll have like an like an 80s horror movie moment with your eyes popping out. I mean, that won't really happen. But um Good. It's like total recall, like on Mars. Um, you know, I think that it's it's not about ingredient, it's about concentration and how something is delivered that actually leads to whether something is safe or or not safe. Um, so that's one thing. Now, I am always on the side of erring with some responsibility or airing with caution, in that if you do not have data, maybe I'll I'll be like the FDA here. If you don't have data on use with in pregnancy and breastfeeding, I just say no. I mean, we we see that all the time in the indications for drugs. If it wasn't ever studied, pregnancy, breastfeeding, you just say no. Now, in special populations, uh like kids, like pediatrics, um, I actually am okay with CBD in this setting. The reason is there have been numerous case reports. There's actually a case series looking at C BD oil for wound healing in an inherited condition called epidermalisis ballosa simplex, which is a horrible condition where in areas of shearing, the skin literally shears off. These kids will get blisters in pressure-dependent areas due to inherited defects in the things that anchor the skin down. Um, and they don't heal well either. So there have been some case series looking at that. There have been other case series looking at CBD and wound healing in general. Um, and we actually published a study surveying pediatric dermatologists in their comfort in recommending CBD-based products or their interest. And there certainly was a lot, and a good number that actually said that they do already. So in the in the pediatric, it's not so much about CBD, it's about what product? Does that product have a COA? You know, there was a paper looking at um dermal hypersensitivity reaction, allergic reaction to a CBD product, but it wasn't to the CBD. It was actually to an excipient uh that wasn't even supposed to be in the product. And that's where that COA comes in. Like what else is coming along for the ride being a natural source ingredient? Is there some junk that came along that's gonna cause problems? And so that's where picking the right product is important. It's not so much about is CBD dangerous in uh in kids.
SPEAKER_01:So CBD in the future, where are we headed?
SPEAKER_03:Oh man, I I'm hoping that uh we put the paddles on and shocked it back to life because you know I remember there was an article in Allure that said RIP to CBD, and it broke my heart. Someone like I'm I'm like mid-clinical trial, and I see this, and I'm like, are you kidding me? And I actually reached out to the author. Um, she actually she actually quoted me related to one of our survey studies about uh public perception of CBD. And I reached out, I said, hey, listen, so I saw your article, didn't love it, but um, I'm working on something that may change your perspective. Can I reach out when it's when it's done? And and the the the reporter, you know, the uh the editor said, absolutely, thanks. And and I gotta say, this is a good lesson. Um, I think we also can assume that people don't want to hear from us or that there's this divide. Always reach out. If there, if you have something to offer or you want to connect, if you see something like especially with media, you'd be surprised nine at 10 times, they will respond very quickly, and you could create a long-term uh engagement that can allow for you to get the right information out there. And so we finished the study, we published it in the JAD, and I reached back out, sure enough, and they did a whole article about the revival and how you need to uh really pursue the scientific method in order to prove claims and points. And so my hope is that we are kind of swinging things around because I think that it would be a shame not to capitalize on all the incredible work that's been done, first in cells, then in animals, and even in humans. Um, to really get to the next level, we need a whole community of stakeholders invested. And this includes industry as well, you know, to get this to the next level with respect to uh maybe even at the prescription level, uh, it takes a lot of effort and, of course, funding. Um, you know, there already is a CBD-based drug out there, Epidelex, which is an oral CBD product for certain types of epilepsy. Um, and we learned a lot about the safety from that. So we know that under 1.5 grams in just in a day is really quite safe. There's no hepatotypes, no real issues. Um, so we actually learn a lot about an ingredient when you go through the rigor of an FDA trial. So I really hope those watching it encourage those decision makers to pursue this, to generate the level of data for those, those in whether it be uh translational or clinical research, to really engage, because I think that there is so much untapped potential. And we focused on photoaging, you know, accelerate skin aging from sun exposure. But I think the ones we things we meant you mentioned before, acne, psoriasis, eczema, wound healing, severage dermatitis, this goes on and on. Um, you know, there was a company looking at a synthetic cannabinoid called Lenobassum, a company called Corbis, for connective tissue diseases like dermatomycitis, scleroderma. There's so much potential here, but you can't skip the line. And I think that's what happened with the farm bill. We jumped from A to Z without doing the work. Um, often a drug takes 20 years from start to finish. You got to put in the work to then have the confidence that this is going to have the effect you want the same way in all patients.
SPEAKER_01:Well, that sounds promising for CBD. In the future, it may hold. So we'll just say we're going out on this podcast on a high. Let's just do that. You know, I like it. Always.
SPEAKER_03:Ah, I see what you did there.
SPEAKER_01:That was I thought you'd like that.
SPEAKER_03:Somewhere a teenager rolled their eyes, but I like it. Yeah.
SPEAKER_01:Well, thank you so much, Adam, for coming on and giving us kind of the data where we're at. I think this will be exciting information for people to pay attention to and to see where CBD takes us into the future, especially with skin.
SPEAKER_03:Yep, absolutely.
SPEAKER_01:And stay tuned for the next episode of Dermotrotter Don't Swear About Skin Care.
SPEAKER_00:Thanks for listening to Dermot Trotter. For more about skincare, visit dermittrotter.com. Don't forget to subscribe, leave a review, and share this podcast with anyone who needs a little skincare sanity. Until next time, stay skin smart.
