Vitality Unleashed: The Functional Medicine Podcast

Fighting Muscle Loss: How to Reclaim Control of Your Aging Body

Dr. Kumar from LifeWellMD.com Season 1 Episode 127

Send us a text

Muscle loss isn't just a normal part of aging—it's an active, preventable process that profoundly impacts your health, independence, and longevity. This eye-opening deep dive into sarcopenia reveals why this condition deserves your urgent attention.

The numbers are staggering: by 80, you could lose up to half your muscle mass. Even more alarming, your muscle power—that crucial ability to react quickly when you trip or need to get up—declines even faster. This isn't just about strength; it's about survival. People with sarcopenia face 2-3 times higher mortality risk from all causes. Yet most healthcare providers simply shrug it off as inevitable.

We break down the complex biology behind muscle aging, from the insidious "inflammaging" process to mitochondrial dysfunction and fat infiltration within muscle fibers. These aren't passive changes but active disease-like processes you can interrupt. The good news? Even a few minutes of weekly resistance training can make a significant difference. Combined with proper nutrition (especially adequate protein) and potentially hormone optimization, you have powerful tools to maintain your physical function.

This episode transforms how you'll think about aging. Rather than resignation to decline, discover how to take control of your physical future through evidence-based, proactive strategies that preserve strength, mobility, and independence. Your later years don't have to mean weakness and limitation—they can be vibrant, strong, and empowered.

Ready to rewrite what's possible for your health span? Contact Dr. Kumar's team at LifeWellMD.com (561-210-9999) to develop your personalized strategy for maintaining strength and vitality throughout life.

Disclaimer:
The information provided in this podcast is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before making changes to your supplement regimen or health routine. Individual needs and reactions vary, so it’s important to make informed decisions with the guidance of your physician.

Connect with Us:
If you enjoyed today’s episode, be sure to subscribe, leave us a review, and share it with someone who might benefit. For more insights and updates, visit our website at Lifewellmd.com.

Stay Informed, Stay Healthy:
Remember, informed choices lead to better health. Until next time, be well and take care of yourself.

Speaker 1:

Welcome to the Deep Dive. Today we're cutting through some common ideas about getting older. You know the gradual loss of muscle strength. Maybe mobility Is it really just, well, normal aging?

Speaker 2:

Yeah, that's the perception, isn't it? Even traditional medicine sometimes just shrugs it off.

Speaker 1:

Exactly, but what if there's more to it? What if you have more control?

Speaker 2:

That's precisely what we're exploring. For too long, it's been about resignation, but control. That's precisely what we're exploring. For too long, it's been about resignation, but this deep dive, it's really about revealing you have, you know, much more agency over your physical future.

Speaker 1:

I like that Agency. So our mission today is a deep dive into sarcopenia. It's a critical but often overlooked age-related condition. Serious muscle loss.

Speaker 2:

And it's not just feeling a bit weaker right, Not at all.

Speaker 1:

It hits your health, your vitality and really your independence hard. We're tackling this using the latest clinical insights, much like the approach at LifeWellMDcom you know Dr Kumar's team there in Florida. They focus on optimizing health, wellness, longevity.

Speaker 2:

Right, they really emphasize that proactive stance.

Speaker 1:

Exactly. We believe you really can control your aging journey much more than you might think.

Speaker 2:

And to guide us, we're drawing from contemporary clinical views on sarcopenia how to spot it, prevent it, manage it, all based on the latest science on muscle aging.

Speaker 1:

It's moving fast, this field.

Speaker 2:

It really is Super relevant for everyone listening.

Speaker 1:

Okay, let's start with the basics. What is sarcopenia? It's a term from what? 1989? Okay, let's start with the basics.

Speaker 2:

What is sarcopenia? It's a term from what? 1989? Yeah, late 80s. At its core, it's the age-related decline in your lean body mass, your muscle. But importantly, it's more than just loss of mass. It includes reduced muscle strength and a decline in physical function too.

Speaker 1:

So it directly impacts your mobility, your ability to just live independently.

Speaker 2:

Precisely, and what's really telling is that even after decades, the medical community is still working on a single universal definition. There's actually a global leadership in sarcopenia group formed just in 2022 to nail this down.

Speaker 1:

Wow, 2022. That shows how important and maybe how complex it really is. It's finally getting urgent attention, definitely. And the numbers? They really paint a picture, don't they?

Speaker 2:

They do. We generally hit peak muscle mass and strength midlife After that. Well, if you're not actively doing something, it's downhill.

Speaker 1:

How steep are we talking?

Speaker 2:

By age 80, your relative muscle mass could drop by 30 to 50 percent.

Speaker 1:

Think about that Half your muscle. Potentially.

Speaker 2:

That's staggering, but Think about that Half your muscle, potentially. That's staggering. But here's something maybe even more alarming your muscle power. It declines even faster than the mass itself.

Speaker 1:

Power like explosive strength.

Speaker 2:

Exactly. We're talking maybe a 10, 15% drop each decade until you're 70. And then it ramps up, accelerates to like 25, 40% reduction per decade after 70. Whoa, so it's not just about lifting heavy things, it's about speed, reaction catching accelerates to like 25 40 percent reduction per decade after 70 whoa.

Speaker 1:

So it's not just about lifting heavy things. It's about speed reaction, catching yourself if you trip that's a huge part of it.

Speaker 2:

Getting up quickly, reacting fast.

Speaker 1:

It's massive functional decline hidden within the numbers okay, so it's really about the function and the speed, not just the bulk of the muscle that's a great way to put it which leads us, unfortunately, to the the serious consequences of sarcopenia. It's not just feeling weak.

Speaker 2:

Not at all. It's directly linked to a much higher risk of falls.

Speaker 1:

And falls in older adults can be catastrophic.

Speaker 2:

Absolutely. They can trigger a whole cascade of problems. Sarcopenia also means a higher chance of disability in just daily activities.

Speaker 1:

Like what.

Speaker 2:

Simple things, you know Walking easily, getting dressed, maybe cooking a meal. They become real challenges and this often leads to more hospital visits and, sadly, a greater need for nursing home care down the line.

Speaker 1:

So it erodes quality of life, but you're saying it affects lifespan too.

Speaker 2:

Directly. It's an independent risk factor for mortality. Some studies show people with sarcopenia have a two, maybe even three times higher risk of dying in any cause compared to those without it.

Speaker 1:

Two to three times. That's significant.

Speaker 2:

And the cost. Think about the health care system. Back in 2000, the estimate was $18.5 billion in the US alone just for sarcopenia-related costs.

Speaker 1:

And that was over two decades ago with an aging population, it's projected to increase exponentially.

Speaker 2:

It makes it crystal clear why tackling these age-related muscle changes is so critical. We need to prevent injuries, disability, premature mortality. It's a massive public health issue now.

Speaker 1:

That really lands the scale of it. It's personal, but it's societal too.

Speaker 2:

Okay. So the big question then is why? Why does this happen? It feels like simple wear and tear, but you're saying it's more complex.

Speaker 1:

Much more complex. It's not just passive deterioration. There are active biological factors really messing with muscle health.

Speaker 2:

Okay, break that down for us.

Speaker 1:

Well, one major player is chronic low-grade inflammation, sometimes called inflam aging.

Speaker 2:

Inflam aging like inflammation that comes with aging.

Speaker 1:

Pretty much Think of it as a low, constant simmer of inflammation throughout your body. It just accelerates aging processes and specific inflammatory markers, things like TNF, IL-6, these reactive oxygen species, or ROS.

Speaker 2:

Oh, sound nasty.

Speaker 1:

They are. They actively contribute to muscle breakdown, muscle atrophy. Even general markers like C-reactive protein are involved.

Speaker 2:

And you mentioned a cycle. How does that work?

Speaker 1:

Right, it can feed itself Mitochondria, the energy factories in your muscle cells. If they get damaged, they can actually release stuff that triggers your immune system.

Speaker 2:

So damaged power plants signal an alarm, exactly, which then fuels more inflammation. It's a really vicious loop.

Speaker 1:

Okay, and what else is going on with those mitochondria?

Speaker 2:

Well, the cleanup process gets slow. There's a process called mitophagy. It's how cells clear out old, damaged mitochondria. With age, that process becomes inefficient. It's like the cell's recycling system gets jammed.

Speaker 1:

So you get a buildup of junky mitochondria.

Speaker 2:

Basically, yes. Dysfunctional mitochondria accumulate and that directly correlates with poorer muscle function. Your muscles just don't work as well.

Speaker 1:

Right, like trying to run on bad fuel.

Speaker 2:

Perfect analogy. And that inefficiency forces your cells into metabolic backup plans.

Speaker 1:

Which sounds problematic.

Speaker 2:

It is. These alternative pathways generate even more of those damaging ROS, those free radicals, and they also create something called advanced glycation end products, ags. Ags yeah, think of them as sticky gunk that gums up tissues and guess what? Higher levels of AGs in your blood are linked to less muscle mass, less strength and worse physical function.

Speaker 1:

Wow, so they're definitely part of the picture.

Speaker 2:

Absolutely implicated. And then there's another piece myosteatosis.

Speaker 1:

Myosteatosis fat in the muscle.

Speaker 2:

Exactly, not just overall body fat, but fat literally infiltrating inside your muscle fibers. This isn't good. This fat triggers pathways that break down muscle tissue catabolic pathways and it makes everything else worse Mitochondrial problems, oxidative stress, inflammation. It pours fuel on that fire.

Speaker 1:

Is that the same as sarcopenic obesity?

Speaker 2:

Related but distinct. Sarcopenic obesity is having low muscle mass and function along with excess body fat. Overall Mycetosis is fat within the muscle itself, which can happen even if you're not technically obese.

Speaker 1:

Okay, got it. So pulling all these threads together inflammation messed up, mitochondria, metabolic issues, fat infiltration, Right.

Speaker 2:

It shows, sarcopenia isn't just your muscles passively fading away. It's an active, disease-like process. These factors are tangled together in a cycle that accelerates muscle loss.

Speaker 1:

Understanding. That really changes things, doesn't it? It shifts the perspective from oh well, I'm getting older to okay. What can I do about this active process?

Speaker 2:

Exactly. And that leads us right into the empowering part actionable solutions. You know, traditional medicine might just note these changes, but places like LifeWellMDcom, they're focused on the proactive strategies.

Speaker 1:

Based on the science showing we can moderate muscle aging.

Speaker 2:

Precisely, and the number one strategy, the cornerstone.

Speaker 1:

Let me guess exercise.

Speaker 2:

Bingo Exercise. It is the only intervention that's been definitively proven to effectively counter age-related muscle loss, full stop.

Speaker 1:

Why is it so powerful?

Speaker 2:

Oh, it does so much. It helps regulate those mitochondria, making them work better, it dampens down that chronic inflammation, it improves how your body uses insulin, which muscles need for fuel and repair, and it boosts your body's own antioxidant defenses against those ROS.

Speaker 1:

Okay, that's compelling. How much exercise are we talking? Do I need to become a bodybuilder?

Speaker 2:

Not necessarily. What's really striking is that even just a few minutes per week of resistance-based exercise can make a significant difference to muscle mass.

Speaker 1:

Just a few minutes, really, yes.

Speaker 2:

Now for optimal results, the general recommendation is moderate to high repetition resistance training, maybe followed by some moderate to high intensity endurance work. But interestingly, studies also show that high repetition, lower load resistance training is highly effective, particularly for protecting against the negative health outcomes of muscle aging.

Speaker 1:

So consistency and targeted effort matter more than just lifting super heavy.

Speaker 2:

That seems to be key. It's about challenging the muscles regularly.

Speaker 1:

Now realistically starting exercise, especially later in life, can be tough Pain, maybe old injuries, fatigue.

Speaker 2:

Absolutely. That's a real barrier for many, which is why a personalized approach is so important. You might need help with pain management, education on doing exercises correctly, maybe specialized supervision.

Speaker 1:

The kind of guidance you might get working with experts like at LifeWellMDcom perhaps.

Speaker 2:

Exactly Tailored support makes sticking with it safely and effectively much more likely.

Speaker 1:

Okay, exercise is king. What else is in the toolbox? Nut.

Speaker 2:

Huge role. Protein is obviously critical. It's the building block for muscle. Now protein supplements the research is a bit mixed for people already getting enough protein, but for those who aren't getting enough maybe very frail people or those in residential care supplementation can be really beneficial. Lots of trials are looking into this right now.

Speaker 1:

So focusing on getting enough protein through diet first, and supplementing if needed, makes sense.

Speaker 2:

Right and beyond just protein quantity, think about diet quality, remember inflammaging.

Speaker 1:

Yeah, that chronic inflammation.

Speaker 2:

Well, diets high in pro-inflammatory foods seem to be linked to lower muscle mass and strength. So, while we're still learning the full extent of the benefits, adopting an anti-inflammatory diet pattern is almost certainly a good strategy.

Speaker 1:

Less processed foods, more plants, healthy fats, that kind of thing.

Speaker 2:

Generally yes, and there's also some research exploring whether antioxidant supplements might boost the positive effects of exercise on those mitochondria. Still early days, but interesting.

Speaker 1:

Okay, exercise nutrition. What about hormones? We hear a lot about hormones declining with age.

Speaker 2:

Nutrition what about hormones? We hear a lot about hormones declining with age. Yes, and that's directly relevant. Certain hormones are vital for keeping muscle healthy Think IGF-1, DHEA, testosterone, estrogen. Their natural decline as we get older is definitely a big factor contributing to sarcopenia and frailty.

Speaker 1:

So replacing them could help. Hormone replacement therapy, or HRT.

Speaker 2:

It's a reasonable strategy to consider yes where it's clinically appropriate. That's the key caveat. For example, we know estrogen HRT can help prevent muscle mass and strength loss in menopausal women. Some studies even suggest lasting benefits after stopping.

Speaker 1:

Interesting and for men, testosterone.

Speaker 2:

Testosterone therapy can increase muscle strength at maximal force output. It can also help inhibit fat buildup and reduce inflammation. So yes, it's another potentially powerful tool.

Speaker 1:

But you stressed clinically appropriate Absolutely.

Speaker 2:

This isn't something to self-prescribe. It requires careful medical evaluation, discussion of risks and benefits monitoring. Like the other areas, clinical trials are ongoing to get more definitive data, but for a personalized approach it's definitely on the table.

Speaker 1:

Okay, let's try and wrap this up for everyone listening. We've covered a lot.

Speaker 2:

We have.

Speaker 1:

We've seen that muscle aging, sarcopenia it's a major issue globally affects health independence.

Speaker 2:

But the main takeaway, the really empowering message, is that it's not inevitable. You don't have to just accept this decline.

Speaker 1:

Right. There are real powerful solutions. We can move beyond just accepting it as normal aging.

Speaker 2:

Early awareness, early intervention. They're more crucial than ever.

Speaker 1:

So for pretty much everyone getting into a regular long-term exercise program, especially that progressive resistance training Is fundamental program, especially that progressive resistance training.

Speaker 2:

Is fundamental. Combine that with really optimizing your nutrition.

Speaker 1:

Enough protein thinking about anti-inflammatory foods, and then, for some people, discussing hormone replacement therapy with their doctor might be part of the plan too.

Speaker 2:

It's about that holistic, personalized strategy.

Speaker 1:

Which really echoes the philosophy at LifeWellMDcom, doesn't it?

Speaker 2:

It does Dr Kumar and the team there. They're all about guiding people through these kinds of solutions, creating a plan tailored to your specific needs for health, wellness and longevity.

Speaker 1:

They understand these complexities of muscle aging and can help you build that effective strategy.

Speaker 2:

They're in charge of the process.

Speaker 1:

Exactly so. If you're listening and you're ready to explore these solutions, to really take control of your wellness journey, maybe learn about a personalized approach to fighting sarcopenia. We definitely encourage you to reach out to Dr Kumar's team at LifeWellMDcom you have them a call. Yeah, the number is 561-210-9999. That's 561-210-9999. It really could be the start of your optimized wellness journey.

Speaker 2:

It's about taking that first step.

Speaker 1:

Definitely. And maybe a final thought to leave everyone with what if aging didn't automatically mean getting weaker, less independent? What if you know, with the right knowledge, the right tools, you could actually rewrite what's possible for your later years, not just adding years to life, but adding life strength, vibrancy to those years?

Speaker 2:

Living better, not just longer.