Ideas at Play: An Occupational Therapy (OT) Podcast
Welcome to Ideas at Play, the go-to podcast for busy pediatric occupational therapy professionals! Whether you're in school-based settings, early intervention, or outpatient practice, we bring you evidence-based strategies, practical tips, and engaging discussions to support your OT practice with children, teens, and young adults.
Each episode features:
- A deep dive into recent pediatric OT research and how to apply it.
- "Nailed It or Failed It," where we share what’s working—and what isn’t—in our pediatric OT practice.
- Real-world examples and listener questions about all things pediatric occupational therapy.
- Shout outs to People, Places, and Products that fill our occupational therapy hearts
Join the hosts, Michele Alaniz, OTD, OTR/L, BCP and Lacy Wright, OTD, OTR/L, BCP, as we explore innovative OT ideas, share professional insights, and help you stay up-to-date with the latest trends in pediatric occupational therapy. Subscribe now and unlock actionable strategies to help the children you serve thrive!
Stay informed, stay curious, and stay playful!
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📧 Email us a question or comment at IdeasAtPlayPodcast@gmail.com
👉 Find us on Instagram @ideas.at.play
Keywords: occupational therapy, OT, pediatric occupational therapy, evidence based practice, peds OT
Ideas at Play: An Occupational Therapy (OT) Podcast
Ep. 49 Folinic Acid and Autism: Translating the Research for Occupational Therapy
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Folinic acid has been showing up everywhere in conversations about autism—but what does the research actually tell us, and why should occupational therapists pay attention? In this episode of Ideas at Play, we break down a high-quality randomized controlled trial on folinic acid and translate the findings into practical, OT-relevant insights. We unpack the brain-based “why,” highlight what the study found (including changes related to autism characteristics and language), and talk about how this information fits into real-world practice. As always, we center participation, functional outcomes, and collaboration with families and medical teams. This episode is for informational purposes only and is not medical advice. Families should always consult their physician before starting or changing supplements or medications.
We share our own thoughts in the Research Review and encourage you to read the original article too.
Panda, P. K., Sharawat, I. K., Saha, S., Gupta, D., Palayullakandi, A., & Meena, K. (2024). Efficacy of oral folinic acid supplementation in children with autism spectrum disorder: A randomized double-blind, placebo-controlled trial. European Journal of Pediatrics, 183(11), 4827–4835. https://doi.org/10.1007/s00431-024-05762-6
Update 2/4/26: The article we featured by Panda et al. (2024) was retracted on 1/29/26. It was discovered that the authors handled the data inappropriately and the journal lost confidence in the findings. Despite this, there is still solid evidence supporting the use of folinic acid with autistic children. Here are a few additional articles that support the information provided in this episode.
Additional Citations:
Hoxha, B., Hoxha, M., Domi, E., Gervasoni, J., Persichilli, S., Malaj, V., & Zappacosta, B. (2021). Folic Acid and Autism: A Systematic Review of the Current State of Knowledge. Cells, 10(8), 1976. https://doi.org/10.3390/cells10081976
Rossignol, D. A., & Frye, R. E. (2021). Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis. Journal of Personalized Medicine, 11(11), 1141. https://doi.org/10.3390/jpm11111141
Sener, E. F., Oztop, D. B., & Ozkul, Y. (2014). MTHFR gene C677T polymorphism in autism spectrum disorders. Genetics Research International, 2014, Article 698574. https://doi.org/10.1155/2014/698574
Bobrowski-Khoury, N., Ramaekers, V. T., Sequeira, J. M., & Quadros, E. V. (2021). Folate receptor alpha autoantibodies in autism spectrum disorders: Diagnosis, treatment and prevention. Journal of Personalized Medicine, 11(8), Article 710. https://doi.org/10.3390/jpm11080710
Stay informed, stay curious, and stay playful!
✏️ Sign up for our newsletter by clicking here.
📧 Email us a question or comment at IdeasAtPlayPodcast@gmail.com
👉 Find us on Instagram @ideas.at.play
