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The Scalpel's Edge
The Scalpel's Edge is a podcast hosted by Dr. Tim Sayed, a leading plastic surgeon and physician innovator, dedicated to exploring the forefront of excellence and wellness. The show delves into cutting-edge medical technologies, industry controversies, and innovative approaches to healthcare and personal growth. With insightful discussions featuring top leaders and innovators from healthcare and beyond, the podcast aims to optimize performance, enhance wellness, and deepen self-understanding. Listeners can follow the podcast on platforms like Apple and Spotify to join this journey into groundbreaking advancements and out-of-the-box thinking.
The Scalpel's Edge
Ep. 27 - What Really Happens When You Stop GLP-1’s and What Might Help You Keep the Weight Off
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Dr. Tim Sayed walks through some recent developments in the GLP-1 space that raise a question almost everyone on these medications eventually asks. What happens when you stop. He reflects on new data around weight regain after discontinuing GLP-1 drugs, including a large meta-analysis showing how quickly weight and metabolic markers tend to return toward baseline once the medication is stopped.
He also breaks down early clinical data on an endoscopic procedure called Revita that aims to support weight maintenance after GLP-1 discontinuation by targeting the duodenum. The discussion stays grounded in real numbers, practical tradeoffs, and the lived reality of patients weighing long term injections versus invasive but one-time interventions.
Along the way, Dr. Sayed addresses cost, insurance gaps, emerging alternatives, and why maintenance is likely the real long-term conversation with GLP-1 therapy. The tone is thoughtful, measured, and honest about both the promise and the limits of current options.
Contact Dr. Tim Sayed:
Phone: (858) 247-2933
Email: info@timsayedmd.com
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