NEUROtrition: Optimizing Your Mind and Body

Tired, Moody, Unmotivated? It Could Be Andropause

Dr. Matt Zaideman, DC, FIBFN-CND, CFMP Season 3 Episode 1

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In this episode of the Neurotrition Podcast, Dr. Z breaks down andropause—the gradual decline in testosterone that many men can begin experiencing from their late 30s into their 40s.

Unlike female menopause, andropause often develops slowly, which means many men may not immediately recognize what’s happening. Symptoms like fatigue, burnout, irritability, anxiety, depression, low motivation, reduced libido, and cognitive changes are often dismissed as stress or simply “getting older.”

In this conversation, Dr. Z explores:

What andropause is and why it can be difficult to recognize
The common emotional, mental, and physical symptoms men experience
Why hormone signaling starts in the brain and how the HPA axis and cortisol play a major role
How stress modulation and vagus nerve stimulation can support recovery and healing
Why resistance training is one of the most powerful non-medical interventions
The importance of looking beyond total testosterone with more comprehensive testing
Key markers to evaluate, including free testosterone, cortisol, thyroid function, A1C, insulin, CRP, and homocysteine
Important considerations around hormone replacement, estrogen balance, and supportive compounds like DIM, calcium-D-glucarate, and Tongkat Ali
Why men need to be proactive with their health before symptoms become more serious

This episode is a reminder that low energy, mood changes, and lack of drive are not always things men should ignore. With the right testing, lifestyle support, and medical guidance, it is possible to improve overall health, performance, and quality of life.

#NeurotritionPodcast #Andropause #Testosterone #MensHealth #Hormones #HormoneHealth #LowTestosterone #Wellness #FunctionalMedicine #HealthPodcast

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