Enthusiastic Life | with Brendan Walsh

Longevity, Medicine, and Metabolic Health | ELP 08 Dr. Sean Cassleman

Brendan Walsh

In this episode, we sit down with Dr. Sean Cassleman, founder of Mission Metabolic Health, to talk about the intersection of fitness, medicine, and longevity.

Dr. Cassleman grew up in Grosse Pointe, Michigan, played football at John Carroll University, and went on to study medicine at Michigan State University College of Osteopathic Medicine. With over a decade of experience practicing Internal Medicine in Detroit and Saint Clair Shores, he’s seen firsthand how obesity, muscle loss, and metabolic disease impact long-term health.

We dive deep into how strength training, nutrition, and metabolic optimization can transform your energy, mindset, and lifespan — and how his practice is redefining what modern healthcare can look like.

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