OutSmart Cancer - Precision Oncology. Less Guess Work. More Life!
OutSmart Cancer is the podcast for people who refuse to settle for one-size-fits-all cancer care. Hosted by Dr. Dino Prato, founder of Envita Medical Centers, this show offers expert insight into the world of precision oncology, integrative treatments, and the hidden factors that make cancer so hard to treat — and what to do about them.
For the last 25 years, Dr. Prato and his team have helped thousands of patients that have failed the largest hospitals utilizing the techniques and technology discussed in this series. Whether you’ve been newly diagnosed, are navigating treatment resistance, or want a second opinion grounded in science and compassion, you’ll hear empowering discussions on: DNA, RNA, and immune-based targeting, the truth behind standard protocols, what most doctors miss in treatment planning, stories of hope from patients who’ve been told “there’s nothing more we can do”
We believe in personalized, data-driven medicine — not protocol-based guessing.
You don’t have to fight cancer blindly. You can OutSmart it.
Disclaimer: This podcast is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before making medical decisions. Results vary and no specific outcomes are guaranteed. Some treatments may not be FDA-approved or available in all locations. Testimonials reflect individual experiences and may not represent typical outcomes. Certain therapies may be offered only at Envita’s international clinic in Hermosillo, Mexico.
OutSmart Cancer - Precision Oncology. Less Guess Work. More Life!
No BS Advice to Avoid Cancer in 21-Minutes
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🧬 About Dr. Dino Prato and Envita Medical Centers
My life's work at Envita Medical Centers has been a mission to help patients find hope when they've run out of options. As a pioneer in precision personalized medicine, I founded Envita Medical Centers to offer next-level care. We use state-of-the-art testing and treatments that are not only data-driven but also precisely targeted to each individual.
By the grace of God, we've been able to help many families. Our approach isn't about treating a disease; it's about treating a unique person and providing a custom blueprint for healing. We believe every life is precious and unrepeatable, and we approach each patient with the love and dignity they deserve. The message we give them is one of life and hope.
📍 Envita Medical Centers – At Envita Medical Centers in Scottsdale, AZ, we believe in a radical, loving approach to patient care. Our unique campus is home to a dedicated team of over 400 professionals, including doctors (MD, DO, NMD), pharmacists, nurses, and researchers, all working together in a seamless ecosystem.
To learn more, visit: www.envita.com
Disclaimer
This podcast is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your licensed healthcare provider before making any medical decisions. Individual results will vary, and Envita Medical Centers does not guarantee outcomes. Some treatments discussed may not be FDA-approved or available in all locations. Testimonials are shared with patient consent and may not reflect typical results. Do not delay or disregard professional medical care based on the podcast's content. Certain treatments may be available only at Envita’s international clinic in Hermosillo, Mexico. No specific outcomes are promised or implied.
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Outcomes Disclaimer
The results referenced from Envita's Precision Cancer Care: 35-Fold Improvement in Response Rates are from a retrospective analysis of 199 late-stage cancer patients treated at Envita Medical Centers between 2021 and 2023, as published in the Journal of Cancer Therapy. These outcomes are not guaranteed and will vary based on individual factors such as cancer type, stage, genetics, immunity and prior treatments. Any comparisons to standard care or clinical trials are based on published data and internal analysis, not head-to-head studies. Individual results will vary.
You can read the full peer-reviewed study at:
https://www.scirp.org/journal/paperinformation?paperid=132493
Most of the advice you hear about avoiding cancer is technically correct, but too vague to actually change anything. It's the same recycled advice everyone has heard for years. And I'm firmly convinced that it's exactly why it changes almost nothing. So today I'm going to give you the advice that I would give my own family, and I'm going to rank them in order to actually give you the impact to help. Not the advice that's the safest to say, not the advice that sounds good on social media, but the advice that changes the terrain of the cancer and how it grows. I'm Dr. Dino Prado, founder of InVita Medical Centers. For the last 25 years, my team and I have worked to help thousands of cancer patients that have failed some of the top cancer hospitals across the country. And we did it using precision targeting. One thing I have to say before I get started is make sure you're working with the doctor before you change anything. Here's the key there is no 100% foolproof way to prevent cancer. But that doesn't mean we're powerless. We can lower risks, we can change the terrain, we can detect it earlier, and we can stop pretending vague advice is good enough. So we can get into how to really help you. Number one, stop feeding the metabolic fire. If I could get people to understand this one thing about cancer prevention, it would be this. You can't ignore insulin resistance, you can't ignore belly fat, and you can't ignore blood sugar, and you can't ignore fatty liver, and you can't ignore metabolic terrain. You can't ignore the lack of metabolic flexibility. This lack of metabolic flexibility is so linked to cancer, but also heart disease, diabetes, and so many of the chronic diseases, and those things that can make our cells worse or more difficult, like environments of high insulin, high glucose, high inflammation, high visceral fat, and low muscle. That's the modern American terrain, or like to call the SAD, the standard American diet. People are overfed and undernourished and under-exercised, and they're not eating the right quality of foods. Their cells are starving for real nutrients like proteins, high-quality foods. They're carrying extra weight, but losing muscle, which also impacts aging and anti-aging. They're drinking sugar in almost all these products, they're eating processed carbohydrates, snacking all day, and sleeping poorly. And they're being told everything looks normal because of their basic lab works aren't terrible yet. That's early metabolic breakdown. A 2025 study in the scientific report found that insulin resistance significantly mediated the relationship between physical activity and mortality, including cancer mortality. So, in plain English, this means that its life-saving benefits of physical activity appear to come from improving insulin sensitivity. Specifically, things like weight-bearing exercise, muscle lifting, or walking and staying active, these open up those GLUT-4 receptors and bring the glucose into the muscle, into the body, instead of staying around in your circulation and causing insulin problems. So here is the no BS version. If your waste is growing and your fasting insulin is high and your blood sugar is creeping up, your triglycerides are too high, your HDL is way too low, and your liver enzymes are elevated, and your energy is crashing after your meals, your body's telling you something. Listen before you get a diagnosis. The everyday version is simple. Stop making breakfast dessert. Stop drinking sugar. Stop ultra-processed foods. Stop pretending fruit juice, cereal, muffins, granola bars, and all these health foods that are disguised as health foods that are loaded with sugar are part of your daily intake because these cause these flexibility problems with your metabolism and they don't help with the prevention of cancer. They make it worse. Here's the easy but powerful facts. Build your meals around high-quality proteins, grass-fed beef, high-quality wild-caught fish, fiber, real foods, healthy fats, omega-3 fatty acids. Walk and stay active after meals, strength train, get good sleep. And then when you go to the doctor, track your insulin, your A1C hemoglobin, your fructosamine, your triglycerides, track your HDL, and most importantly, your waist circumference, your liver markers, and your body composition, your energy, your metabolism, your morning erections. These are all circulatory signs that you can track at home. Prevention starts with this metabolic honesty. Number two, build muscle like your life depends on it. Muscle is not vanity. Muscle is not just for bodybuilders that are taking hormones. Muscle is one of the largest glucose clearing organs in your body. And the biggest muscles you have are in your legs. So things like squats and working and walking and biking, all these things are going to help you. Muscle helps regulate insulin. Muscle helps control inflammation. Muscle supports mitochondrial density. Muscle releases myocines, which are these chemical signals that communicate with your immune system, your liver, your fat tissue, and your brain. And in cancer patients, muscle and fitness are not small details. They're survival biology. A 2025 study, systematic review of a meta-analysis in the British Journal of Sports Medicine looked at nearly 47,000 cancer patients and found that higher muscle strength and cardiorespiratory fitness were associated with 31 to 46% lower risk of all-cause mortality compared to those with lower strength and fitness levels. That's not about looking good in the mirror. That's about energy and reserves. And when a cancer patient loses muscle, they get these loss of muscle from the cancer, or as you're aging sarcopenia, they lose appetite, they lose strength, they become frail. And that's not just a side effect. That's a warning sign that the body's losing reserves. The immune system is under pressure. The mitochondria are under pressure. The patient's ability to tolerate treatment may be under pressure. If I'm talking to a family member or a patient or our doctors are, we're going to talk about this in plain English. Lift weights, do resistant training, build muscle, preserve muscle, track your strength, and do not wait until you're sick to build these reserves. You can start them as young as in your teens and use it throughout your life. You can start older in your 60s and 70s and still build muscle. A 2025 study out of the UK Biobank study found that higher grip strength and muscle mass were associated with lower pancreatic cancer risks. Pancreatic cancer is tightly connected to metabolic function. Our pancreas makes insulin. Insulin resistance is linked to this, diabetes, inflammation, all to the organ of the pancreas. So the advice is not just about exercise. The advice is do resistance training three to four days a week, four to five times a week if you can. Focus on big muscle groups, legs, your glutes, back, chest, shoulders, push and pull exercises, squats, hinges, carrying things, walking daily. And if you're going to do some cardio and weights on the same day, lift first and then do your cardio. You're telling your body keep the muscle, build the mitochondria, clear the glucose, and give me metabolic flexibility. So number three, stop losing weight the wrong way. Everybody wants to scale down and lose weight, but not all weight loss is good. To lose fat is great, but to lose visceral fat is even better. But if you lose muscle, you crash your hormones, you undereat your proteins, you overdo the cardio, and you become weaker. And that's not healthy. That's especially important with these aggressive diets and people that are using the GLP1 medications. These GLP1s can be powerful tools used correctly in microdoses. But if someone uses them and does not eat enough protein and build enough muscle strength and have enough hormones and growth hormone, that doesn't change your body's composition the way we'd like it. We don't want to lose muscle. We want to quickly build muscle and we want to improve our metabolism. We want to bring the fat down and we want to build the muscle reserves, increase strength, improve insulin sensitivity, decrease inflammation. And that's the target, both for the prevention of cancer and even to help if you're in the middle of treatment. So the scale is not your best marker. It's fat mass and muscle mass. And strengths are better indicators of whether your body's actually moving in the right direction. So the no BS advices stop worshipping the scale, measure what matters: body fat, waste, muscle, grip strength, fasting insulin, A1C, hemoglobin, triglycerides. You can look at your HDL, your C reactor protein for inflammation, liver enzymes, check your sleep quality, your movement, and your strength. Tracking that are going to make a big difference because what gets measured gets managed. Number four, eat protein like you're rebuilding a body, not decorating a plate. If resistance training is the signal, protein is the building material. You cannot preserve lean tissue with coffee for breakfast, a salad for lunch, and a tiny dinner. And that's where a lot of people over 40 are in trouble. They're not eating enough quality protein. They're not getting the right building materials that their bodies need, especially if they're trying to lose weight, especially if they're fasting too aggressively. For many people, trying to build or preserve muscle, a target of around one gram of protein per pound of body weight is a good place to start. Some may need a little less, some more, but that gives you a good place to start. And if you have kidney disease or cancer, cachexia, digestive issues, work with a doctor to coordinate these things. Maybe a good high-quality nutritionist or a functional medicine doctor would be even better. But the principles are the same. We want muscle and we need protein to build that muscle. Most people do better spreading their protein across the day. So you try 30 to 40 grams, maybe four times a day. You get it from things like eggs, wild fish, organic poultry, grass-fed beef, bison, wild caught meats, organic Greek yogurts, clean protein powders, bone broth, and even plant protein that's of high quality. If you're trying to prevent disease by starving the body, that's not the way to go. The key is to build strong muscle. So number five, fix the mitochondria. This is the powerhouse of the body. Mitochondria are not just energy factories, they're decision-making centers. They help regulate oxidative stress. They control apoptosis, which has programmed cell death, telling cancer cells to just die off. They help determine whether damaged cells are cleaned up or they're allowed to stick around and survive. They influence immune function and inflammation. They influence repair. And in cancer prevention, mitochondrial health matters so deeply. Now, the no BS version is this: you do not fix mitochondria with one magic supplement. You fix mitochondria with signals, resistance training, walking, high quality protein, sleep, gut microbiome health, where you're eating a lot of quality of fruits and vegetables, particularly vegetables and different things your body can digest to help your gut microbiome, nutrient-dense foods, healthy fats, reducing toxins, and improving insulin sensitivity. And this will support the membranes of the mitochondria. In a 2025 review on physical activity and cancer incidence and mortality, summarized the mechanism that may explain the cancer protective effects of physical activity, including lower body fat, improved insulin resistance and hormone regulation, improved redox balancing, and stronger antioxidant defense, and reduced oxidative stress. That's the bridge. Muscle. That's the key. So muscle activity improves these things, improves insulin sensitivity, it improves the terrain, it reduces inflammation, it supports chronic disease and cancer progression in a big way. So that's why I want people to think about it differently. Not just calories, not weight loss only, but terrain, not just vanity, but biology. Number six, rebuild the membranes. This is one of the things that I think is overlooked by almost everybody. And one of my personal favorites that people really need to add. And I think it's so important. Every cell in your body, including your mitochondria, they have membranes. And those membranes need building blocks so that they can repair and heal because they've handle communication. It helps determine what gets in and out of the cells, including things like glucose, insulin receptors. It deals with inflammation signaling, energy production. The membranes are stiff and old and inflamed and oxidized. They're damaged. They're going to be a higher risk for cancer. If your membranes are supported and healthy, they have high omega-3 fatty acids, like high-quality fish oils that are free from heavy metals and toxins, or wild-caught fish, antioxidants like azanthins, liposomal, which are like the rebarb inside of those membrane walls, things like phosphatidylcholine, these healthy fats. This is part of that clean nutrition with food. That's going to make a big difference in replacing those cell membranes. That's why I like phosphatidylcholine. It's one of the major phospholipids involved in the cell membrane. So I think about the membranes because they're overlooked by everybody. But if you have the right building blocks, just like you will with protein for your muscles, you're going to rebuild these membranes and give your body new cellular membranes, better flexibility, mobility, improves the signaling. That currently might be poor because they're old. See, poor healing creates vulnerability. Then I like to think of things like fish oil. Around 3,000 milligrams per day, like EPA DHA, they're appropriate because they help with the cell membranes, they help with inflammation. Be careful if you're ready on blood thinners, make sure you're working with a doctor because these things will help your blood be thinner. But thinner blood is great for cancer patients because it reduces metastases. And when you add it with liposomal xanthins that are fat soluble, it adds like a unique lipid membrane with rebarb. And so anytime you have oxidative stress that causes cancer sometimes, these reactive oxygen species that can cause oncogenes to turn on, you're shutting them down before they become a problem. So now just imagine you're exercising, your inflammation is under control, you're getting the toxins out of your diet, you're helping with the antioxidants, the cell membranes, you've changed the gain. So my prevention stack includes the phosphatidylcholine, that fish oil, and the liposomal laxanthins, because these play an important part of health and energy at the cell membrane or the mitochondria and the rest of the body. Then we supercharge our metabolism and our mitochondria with resistance training and protein to build muscles. And then we add sleep to help with repair. And then we add precision testing to know what's actually happening. That's prevention at a very high level. Number seven, understand that muscle talks to cancer biology. The muscle contracts and releases signal molecules that are called myokines. Think of myokines as a chemical text message released by your muscle during exercise. They communicate with your immune system. They communicate with fat tissue. They communicate with your liver and your brain and your metabolism. And some of these myokines appear to have anti-cancer signals. In a 2025 study in breast cancer survivors found that a single section of resistance training or high-intensity interval training increased anti-cancer myokines and reduced the growth of breast cancer cells in vitro. Exercise is not just about burning calories, it's about changing signaling, changing those myokines, those signals from our muscles, like 600 plus of those, changing insulin, changing mitochondria, and inflammation, all in our favor. So our internal terrain is healthy. And that's exactly how I want you to think. Not just calories, but not just weight loss, not just vanity, but putting all these things together to improve the biology of your body. Number eight, stop obsessing over this low-level stuff. We want to go after the important stuff. This is where I want to be a bit direct. People will spend hours debating the perfect mushroom powder, the perfect detox tea, the perfect red light device, the perfect biohacking gadget while they're sleeping like five hours a night, carrying belly fat, eating processed foods, drinking alcohol, avoiding resistance training, and never checking their insulin levels. That's backwards. I'm not saying those tools aren't helpful. They're great, but some may be more useful than others. You need to get these basics down before you add anything else to your protocol. Some of these things are supportive, but the foundations, like don't smoke, don't drink alcohol, you know that. But fixing insulin resistance is one of those foundations, building healthy muscle, eating high-quality protein, eating real foods that are non-processed, that don't have the chemicals, sleeping better, staying active, lowering that visceral fat. So whether you're walking or cycling, you're trying to stay in that zone two to build that mitochondria for your exercise, reducing toxins, and getting the appropriate screenings like early cancer detection tests. Now you're moving at a whole different level. Knowing your family history is helpful, but most cancers are not genetic. They're epigenetic, they're from changes of our diet and lifestyle. So here's the rule: do not use advanced tools to avoid basic discipline. Number nine, stop poisoning the terrain. I'm gonna say this in plain English: no smoking, no vaping, no drinking heavy alcohol or processed foods. Try to avoid pesticides as much as you can, plastic, solvents, mold, endocrine disruptors that are in our environment. It's hard to get rid of all of them, but just reduce that. So it's not overwhelmed every day and you have low sleep and feel fatigued or you have lots of inflammation. You need to overcome these things. This is not about fear. This is about reducing the burdens of these toxic foods and eating the healthier ones. And you've heard this over and over again. It's common sense, but putting it all together and majoring in the majors and not in the minors. Number 10, take sleep seriously. Go to bed on time. You're just gonna feel better. It's even great to take naps. Anything you can do to help you get rest is gonna be so good for your body and heal. Our body needs these things. These are just fundamentals to health. And there are no medications as good as these fundamentals. So the no BS here is go to bed, get morning sunlight, cut the caffeine, keep the room cold and dark, and don't eat giant meals at night, maybe a little protein so your glucose doesn't drop. That's gonna help you with prevention. Sleep is so important and often ignored by so many. It's a repair window for our bodies and for our health. Number 11, detect early. Now we have these multi-early cancer detection tests where we can look at almost all the cancers with a simple blood test. If it's positive, we run imaging. If we see imaging, then we biopsy it and we can diagnose it. We find it early, we remove it, and we're done. We change diet, lifestyle, exercise, and people move on with their life. Yes, it's good to know family history, but to be honest, people even outside of family history are getting cancers earlier. Statistically, almost half of all the population will get cancer. So we all need to be testing. If somebody finds they have cancer and it's already spreading, now we want to do precision oncology. That's where this matters. DNA testing for next generation sequencing, RNA transcriptomics, immune profiling, and immune spatial biology. So we know the tumor microenvironment and we're not falling to the one size fits all standard of care. I'm talking about using a thousand plus markers instead of like 24, a biopsy, a tumor marker, and imaging. Because cancer is not just about breast, colon, lung, pancreas, you name it. It's about immunity. It's about proper targets, it's about terrain. And that's the focus of the work we do. And that's why I believe that's so important because in our published paper, it shows to improve outcomes by 35 times when you have the data. We can map it out deeper and create the custom treatment plan for the patients who need that. Everybody needs to be looking at this dietary and lifestyle changes that I'm talking about because they're simple to incorporate, they're focusing on the right things, and they're helping our body heal. Now, if you had to compress the whole episode into the advice I would like to give to family members and our patients, don't smoke, don't drink heavenly, do not live metabolically broken, build muscle, walk every day, stay active, resistant training, eat high-quality protein, fix that insulin resistance, support mitochondrial health, support the membranes, the healthy fats, phosphatidylcholine, omega-3s, antioxidants, and liposomal health. That's going to make a big difference. Things like axanthins and antioxidants are very powerful. Get plenty of sleep, reduce your toxins, get rid of their fine carbohydrates, and test intelligently and screen intelligently and appropriately. And if cancer appears, you don't have to worry because you'll find it in a small size that you can remove and move on with your life. And that's the no BS version. Not because it's flashy, but because it's the bottom line. It's what I've seen and what I can tell you, I think is the way forward. A simple way to do this is just to pick one of these things and change these every week. Go lift weights three to four times a week. That might be what you want to start with. Walk after every meal. Get rid of all the refined carbohydrates and sugar products and get your fasting insulin checked and schedule your screenings. Stop drinking soda beverages and you're already on the right track. So you can just add these in and slowly build these into your routine until you optimize your body feeling great. There's so much advice out there that leads you in the wrong direction. All these programs are telling you how to eat, what not to eat. And I'm telling you, these are the basics. You incorporate these things, they're gonna see true changes, and you don't have to push around by all the nuances out there, but you can follow good sound advice that's gonna help you. So now that you've got my list and you can put it to work and lower your risks, that's really important. Now the flip side of this is just as useful, knowing the things that actually increase your risk of cancer. So you can click on this video here to help you with that because I walk you through what I'd call the fastest way to get cancer in 2026, the everyday lifestyle factors and the strongest evidence behind them, and where the real risk actually sits. If today's video made you want to do something, that one tells you exactly what to stop doing. I hope you found this episode helpful and it gave you a lot of tools that you can implement quickly into your life. And may the Lord bless you on your journey to healing.