The Best AI Show on Pharma
In a world where healthcare decisions are getting faster, smarter, and more complex, one force is quietly reshaping the entire pharma landscape: intelligence. Not the kind you read in reports, but the kind that emerges when data, science, and experience collide. The Best AI Show on Pharma steps right into that intersection. Hosted by Ayush Mishra, this podcast brings you candid, future-facing conversations with leaders who are redefining how medicines are discovered, developed, and delivered.
Each episode goes beyond buzzwords, beyond hype, and beyond surface-level talk. These are the real stories, the challenges no one admits, the breakthroughs no one sees coming, and the visions shaping the next decade of medicine. Whether you are a pharma professional, a healthcare innovator, or someone who believes that smarter technology can lead to better outcomes, this is where the future becomes understandable, practical, and actionable.
The Best AI Show on Pharma
Ep #3 | Beyond the AI Hype: Real Solutions for Clinical Trial Efficiency with Ayush Mishra and Suzanne Vyvoda
Clinical trials don’t fail because of bad science, they fail because the operations behind them are broken.
In this high-signal episode, Ayush Mishra sits down with Suzanne Vyvoda, a 20-year clinical operations veteran who has built teams across 40+ countries, scaled billion-dollar trials, advised CROs, biotech founders, and helped companies cut trial costs by up to 25% without compromising quality.
From the chaos inside clinical sites and the “Excel tracker economy” that still runs global trials to the quiet operational failures that delay drugs, inflate budgets, and frustrate stakeholders, Suzanne breaks down what really drives clinical trial inefficiency, and why AI alone won’t fix it.
But this isn’t a pessimistic take.
We unpack where AI is actually working, which use cases offer real ROI today, why RWE is becoming operationally strategic, and why the future of drug development won’t be about replacing people, but augmenting them.
In This Episode, You’ll Learn:
- Why clinical trials are still powered by spreadsheets and PDFs
- Why sites, CROs, and biotechs are all frustrated, and all correct
- Why tech adoption fails when it adds work instead of removing it
- Why RWE + site intelligence is the next frontier of feasibility
- How good contract design alone can cut trial costs dramatically
- Why “ecosystem fluency” is the missing skill for AI founders
- Why CROs fear tech, and why that incentive structure needs to change
- Why the right MVP solves one problem, not 27
- Why the next wave of tools must feel native to real operators
If you want a real look at how trials actually run, from budget to operations to site burden to CRO incentives, and clarity on where AI fits (and doesn’t), this episode is unmissable.
Watch till the end. Your understanding of clinical operations will change.
Connect with Ayush Mishra
https://www.linkedin.com/in/ayushmishra/
Connect with Suzanne Vyvoda
https://www.linkedin.com/in/suzanne-vyvoda/
Watch on YouTube
https://youtu.be/dalypa2iYi0