The Best AI Show on Pharma

Ep #4 | Accelerating Clinical Trials with Real-World Data, Know What Actually Works with Ayush Mishra and Chandi Kodthiwada

Ayush Mishra Season 1 Episode 4

The pharmaceutical industry doesn’t struggle with scientific innovation, it struggles with execution. Feasibility, enrollment, evidence generation, and regulatory confidence remain the biggest constraints on getting medicines to patients faster.

In this episode of The Best AI Show on Pharma, Ayush Mishra speaks with Chandi Kodthiwada, Vice President, Product Management, Komodo Health, whose work sits at the intersection of real-world data, clinical development, and AI strategy across the life sciences ecosystem.

While for more than a decade building data products for biopharma, Chandi explains why most AI initiatives stall, why clinical trial operations remain deeply inefficient, and why real-world evidence is becoming a strategic lever rather than a research afterthought. From feasibility to enrollment to post-market monitoring, we explore how data is reshaping drug development and where the industry is actually seeing ROI.

This is not a futurist conversation, it’s a grounded look at what’s working today, what still breaks, and what needs to change for AI to truly matter in biopharma. Also get ready to know some deets on the recent partnership that happened between Komodo Health and Anervea.

What You’ll Learn in This Episode:

• Why AI pilots struggle inside pharma organizations
 • Why 30% of clinical trial sites never enroll a patient
 • Recent partnership that happened between Komodo Health and Anervea
 • Why RWE is gaining regulatory traction beyond publications
 • Why consulting isn’t going away, but the slide work is
 • Why trial bottlenecks are now operational, not scientific
 • Why structured context beats model complexity in real use cases
 • Why execution is the new competitive edge in drug development
 • Why startups need ecosystem fluency, not just technology

If you’re involved in clinical development, RWE, regulatory, digital, medical, or commercial strategy, this episode offers a clear lens into where the industry is headed, and what’s required to get there.

Connect with Ayush Mishra

https://www.linkedin.com/in/ayushmishra/ 

Connect with Chandi Kotriwada

https://www.linkedin.com/in/chandikodthiwada/

Watch on YouTube

https://youtu.be/XIHNrAbE5N4 

Watch Now on YouTube