Peptalk: Peptides Unpacked

#16 How A Little-Known Peptide Revives Libido For Men And Women

• Dr. Kylie Burton & Jessica Briecke

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Libido. Desire. It starts in the brain. Ever heard of PT-141 (the peptide)? It can reignite sexual motivation for women and men by targeting central pathways that drive want. 

From the “whatever” phase that creeps in with menopause or long-term stress to the postpartum crash that blindsides new parents, we get honest about why libido fades and what it takes to bring it back without awkwardness or guesswork.

We break down how to use PT-141 for real life: 

  • why it isn’t a daily routine, 
  • how the two-to-six-hour window works, 
  • and how to time it for morning, afternoon, or evening plans. 

Along the way, we share candid stories, evidence-informed insights, and simple habits that make intimacy feel inviting again: lighten the pressure, set the stage, and let brain-first signaling do its work. 

We encourage you to be brave and take action in secret. There's a Valentine's Day Special dropping February 4th for the first 5,000 orders. It's the new PT-141 Spray called Elate. Order quickly so you get your special gift with it—now’s the moment to plan date night with intention and a little science on your side.

If this helped you rethink libido, tap follow, share with a friend who could use the spark, and leave a quick review so more people can find the show. Your stories and questions guide future episodes—tell us what you want us to unpack next.

Want to connect more with the hosts? We'd love it! Connect with Jess at B2BwithJess.com/peptides or on Instagram @JessB_LMT_NC. Connect with Dr. Kylie at her other podcast Unshakeable Brain.

Ready to explore peptide therapy for yourself? Visit the company we recommend for advanced peptide therapy and one-on-one support at drkylieburton.com

Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll help you make the sales and marketing much easier—at drkylieburton.com

Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.

You have the science. You have the tools. Now it's time to take the next step.

This is PepTalk: Peptides Unpacked—science made simple, results made real.

SPEAKER_01:

Peptides are powerful and often misunderstood. And we're here to change that. I'm Dr. Kylie Burton. And I'm Jessica Brickie. This is Pep Talk. Peptides Unpacked. Science made simple. Results made real. Libido. That's the name of today's episode. Why? Because there is a peptide that will just change your life. Whether you're a man or a woman, it doesn't matter. PT141. Have you ever heard of it? Well, if you haven't, definitely listen in because we've got Valentine's Day around the corner, and this just might give you that extra spark you need to make this year extra special. All right, Jess. PT141 and libido.

SPEAKER_00:

Holy moly, so I think that when people start talking peptides or things that we're gonna put into our body, the first thing that comes to mind is the little blue pill, and our body is gonna is gonna respond, and it's just for men, it's gonna respond in that way, which by the way, women can do too. We only talk about men and their needs. But in this particular case, we're talking about a really exciting peptide that is not geared towards blood flow, but is geared towards what's happening in our brain. I think that a lot of women go through menopause and experience low libido. I think it's a really it's probably pretty common. I'd say probably most women I know my age could care less if they're in the bedroom with their spouse ever again. Like that's literally it's like dead. They feel nothing. This peptide we're talking about, PT141, is kind of like, hey, I like my spouse again. I like you. Let's see what happens. It's a brain thing. Years ago, I heard a I was what you know, Oprah was big with her thing, and she had on Demi Moore and Bruce Willis. Remember way back in the day when they were married, and there was a part where they were talking, and Demi said something like, Some days you just wake up and you look at your partner and you go, yuck. And that had to have been like 25 years ago that I heard that. I don't even know, like, time is weird, so I have no idea how long ago they were married and when that interview happened. Could be longer for all I know. And it always stuck with me because at the time, my husband and I were young, newly married, and I could not even imagine a time when I wasn't hot for my husband, like raring to go. Fast forward, my husband and I are going to be celebrating 30 years of marriage this year. And I don't know that I would say that I look at my husband some days and go, yuck, but there are days that I go, whatever. And how sad is that? Because you know, you miss that intimacy and you take it for granted when you're young or when you're first together, and our brains are meant for procreate, like we're wired for procreation, scientifically, right? We are meant for a male and female to get together and procreate, and that ultimately to reproduce life, and that ultimately is how our bodies work. So when we're younger, we have things within us that give us that attraction that make us want to mate. And then as those as we age or we have stress and hormones change, that signaling in our brain changes, and now we become more nurturers, we got to take care of business, and it becomes less about what happens in the bedroom now, more about taking care of life. But most of us really enjoy what happens in the bedroom. But how do you get back there if you don't care? Like the spark literally don't care. How do you bring the spark back? And I'm not as I'm not I'm not a sexual wellness expert, but I can tell you that in the 30-something years in my office, this is a conversation that comes up that are no longer having intimacy with their with their partner the way that they used to. And we we just it's normal. Everybody's doing that, they're no longer interested. So now there's a peptide, and it's not a peptide that you take and 20 minutes later you're raring to go. It's something that you take maybe in the afternoon when you think maybe tonight's the night, or whatever the timing is, like you, it's a window, like two to out two to six hours, something like that, that starts signaling your brain to say, Oh, I like that person. That yuck is gone. I'm interested. And it increases sexual motivation, like the drive to want to have sex again, the increase in libido, and our response, the arousal. So it's all this brain signaling in it's happening, which is different from that little blue pill. It is not a daily peptide, it is a couple times a week that you would use it. Um, it's not recommended for daily use. And uh it's it's literally saving marriages, changing relationships, creating connectivity that you didn't think you were gonna have again in your life. And Ellie's doing it right because we are celebrating Valentine's big this year.

SPEAKER_01:

Before we jump into this celebratory this month on February 4th, when it drops, um you know, I'm 36, very different age group than your menopausal age group, which you're like, oh, I'm getting so much things to look forward to. Thank heavens we have the PT141. But for my age group, it's postpartum. You know, for me, I'm my libido is through the roof during pregnancy, and then it's like after pregnancy, the crash happens. And my husband's always like, Can we just go back to your pregnancy days without all the pregnancy but it's like he's 40 years old, his testosterone was so freaking high, I don't even maybe we have something to bring his down. Um, but I've you know, I've had conversations with friends, I've had conversations with colleagues at conferences where it's like, you know, we haven't had uh sex in three years or six months, and I just look at them like, wait, what? You don't have you not have the drive? You like, where's your libido gone? Like, that's crazy to me. And it's reality for a lot of people. So I love how this is an option, and you can do it in secrecy.

SPEAKER_00:

You can, it comes in a maybe it comes in a box, that's secret. I don't know. Well, it's shipped like any other peptide, it's gonna be shipped in cold pack conditions, nobody's gonna see it. But I think what you're getting at too is that when somebody places an order, um, when they go in and there we refer them to the telemedicine company, when they go in, they place an order because of HIPAA laws, we're never gonna see what it is. You and I, or whomever you're working with, never going to know that you are ordering something for what's happening in your bedroom and needing support that way. So that's protected, and then it comes in a cold pack. And even honestly, if the male person or your kids got the mail and they open a peptide and it says PT141, they don't know what that's for.

SPEAKER_01:

Even if they're teenagers, they have no idea what it's for, they don't know what that's for. Um, so let's talk about this. February 4th is when it's gonna go live. There are 5,000 available. Uh, Valentine's Day can be a rough one. It was once for me in my college days. My my parents would always send me flowers because they knew how much I hated the day. And I would usually spend like the whole day in the library or something, just distracting myself from the singleness of my life. That seemed to be always be the case until Andrew came along because I only dated one person before I met Andrew. Um, I always said I dated it to volleyball, and that was good enough for me because it did exactly what I told it to do. So I know Valentine's Days can be rough. I also know that there are relationships in rough situations, and having a little bit of drive, a little bit of that activator happening in the brain, providing the libido, the spark, as we'll call it, can really, really help. And it can probably change the tide of relationships as you've mentioned before. So tell us what's going down on February 4th. And I want you guys to know it's February 4th, and there are only 5,000 available, so you need to act as soon as you possibly can after the 4th.

SPEAKER_00:

Yep. So Ellie has not only the PT141 that we were talking about, but they have something else. It's called the thrill pill, and it's a lozenge, it's it's uh troche, but it's really a lozenge that you put in your mouth, and this it works differently than the PT141. This is something that you would take close to the time that you think that you want to be intimate, and it has not only a little bit of PT141 in it, it also has some oxytocin in it, it has uh uh tadalophil in it, and that is gonna, for men and for women, get you ready to roll. But next week we are going to have that available as a nasal spray. So that's gonna come out as a nasal spray, and along with anybody that orders the first 5,000 people that decide that they want to give this a whirl, the owner of the company thought it was a really good idea to give a Valentine's gift for those 5,000 people in the form of the TikTok viral rosebud personal massager. And I didn't know what that was. So last night I went down the TikTok rabbit hole.

SPEAKER_01:

TikTok Road.

SPEAKER_00:

Holy moly, let me just say, if you're listening to this right now and you don't know what I'm talking about, I would say go on TikTok and put in rosebud personal massager or TikTok viral rose, Google it, whatever. It'll bring you into all these people that are talking about their experience, what it is, what it does, how you use it, and you are gonna want to be one of those 5,000 people that are on board. Whether you're a woman and you want it for yourself or you're a man and you want it for your partner, this is this is pretty freaking cool. This is a lot of fun.

SPEAKER_01:

Yeah. So to get the Rose gift, we have to buy the nasal version.

SPEAKER_00:

Yeah, I I believe. So I don't know as the time of this recording, I don't know that we have officially. Um and see if we did put in the details of what it is, but what it was told to me last night on our call, it's the spray purchase, which is the new thing we're launching next week, of the thrill pill. And that's gonna come with this personal massager, this rosebud viral massager. Just pulling that up right now.

SPEAKER_01:

So if you need an extra spark, whether it be on Valentine's Day and days afterwards, I'm thinking like you take it before date night, before you go out for date night, and then when you come back for date night, you've got the the spark rolling.

SPEAKER_00:

Yeah, I don't have I must have gotten rid of the email so I don't have it right in front of me, but it is something that you would use on the the the spray or the lozenge, you would do that right before, you know, that's because it happens pretty darn quick. Um, and the PT141, um, that is something that you would take date night day, like afternoon. Um maybe, maybe you're a morning person, so you're gonna maybe get up early and take it. If you're a morning person, if you're a afternoon delight person, you're gonna take it in the morning. If you're an evening person, you're gonna do it at that. You're gonna do that injection in the afternoon. Um, because that PT141 injection, two to four hours before you brain signaly start saying, Hey, I'm interested, and then the lozenge or the spray, that's gonna be something that you do right before you're ready to get going.

SPEAKER_01:

Okay, labido fixer upper. PT141 thrill pill and the spray, whatever they end up naming it. Go grab it. It the gift is available February 4th for the first 5,000 who purchased the spray. So give yourself an extra Valentine's Day gift. Give it um recommend it to a friend if you know of somebody who could use a libido booster and get that spark back in their relationship and uh get a whirlwind. All right, Jess, where they can they find you?

SPEAKER_00:

You can always follow me on Instagram. I am Jess B underscore LMT underscore N C. You can also come on board with me and get your peptides or start a business with me, anything you want to do, and you're gonna find me at b2bwith.com backslash peptides.

SPEAKER_01:

If you're not from Jess, go to my page, drkylieburton.com slash peptides. You can get started there. All right, go grab your spark and let us know if you would like to, or you can do this in secret. Totally fine too. Secrecy is probably what 99% of people are gonna do. Go for it. And you can thank us later. Thank you for joining us until next time. I can't wait to hear that.