Voices

04: A Sister’s Illness Sends A Medical Student Into Life-Altering Research

• GMR • Season 1 • Episode 4

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Cultural Warning: This episode contains the name of an Aboriginal and/or Torres Strait Islander person who has passed away.

A rare infection. A Brisbane family tragedy. A young researcher who refuses to stop asking “why”. We’re joined by Kirby Patterson-Fahy, a 23-year-old medical student and emerging scientist at Gallipoli Medical Research, whose path into medicine begins with her sister Anastasia "Taisie" becoming seriously unwell and spending months in hospital. Kirby shares what it’s like to watch clinicians face unanswered questions, and how that uncertainty pushed her to start reading research papers long before she ever stepped into a lab. 

We follow the thread that led Kirby to Professor Rachel Thompson’s work on non-tuberculous mycobacteria, including evidence that Mycobacterium abscessus can be grown from tap water in Brisbane. That discovery doesn’t just change how a family thinks about exposure and blame, it opens up the deeper scientific problem: if so many people are exposed, why do only some become dangerously ill? Kirby explains the role of underlying vulnerability, why NTM infections can be hard to diagnose and treat, and what makes mycobacteria so resistant to common antibiotics. 

Kirby also talks candidly about building a life that can hold both clinical training and medical research: early-morning swims, tight scheduling, learning the “why” behind guidelines, and seeing how evidence-based medicine is actually made. Along the way, we hear about growing up with two mums, foster sisters, and a strong sense that family is defined by care, not biology. If you care about Australian medical research, antibiotic resistance, mycobacteria, and the future of clinician-scientists, this conversation will stay with you. 

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Welcome To Voices At GMR

Host Miriam Kent

Hi everyone, I'm Miriam Kent, CEO of Gallipoli Medical Research, and I'm delighted to welcome you to our new podcast, Voices. Tune in as we bring you raw conversations with leaders, survivors, researchers, and advocates across veteran health, medical research, clinical trials, and the broader community. From a Victoria Cross Medal recipient and a mother of two surviving stage four melanoma, to Australia's first female three-star lieutenant general, their voices will transform the way you think about service, leadership, and what it truly means to stand beside one another during life's hardest moments. We have entrusted the master conversationalist Sarah Maxwell to sit down and facilitate these important conversations. Sarah, over to you.

Conversationalist Sarah Maxwell

Today we sit down with second-year medical student and young researcher Kirby Patterson- Fahy. At only 23 years old, she has already completed her Bachelor of Advanced Science and Microbiology at the University of Queensland while conducting important research at Gallipoli Medical Researches Lab under Professor Rachel Thompson. Attending major conferences like the American Toracic Society in Washington in 2023 and Mycobacterium in Colorado in 2025, alongside her GMR supervising professors, exposed Kirby to a wealth of physicians. These experiences surely will impact the medical doctor she will become. Kirby swims every morning, except for this morning, at 5:30 a.m. before her medical placement. She is one disciplined and focused young woman. Welcome, Kirby to Voices, GMR's new podcast designed to capture the sentiment of incredible women and men like yourself who conduct medical research to improve the health and well-being of veterans, their families, and the broader Australian community. So welcome, Kirby. I can't wait to hear

Meet Kirby And Her Path

Conversationalist Sarah Maxwell

more about all these amazing things you do. Thank you. And sorry for exposing your swimming, because normally, guys, it was cold this morning. But this girl, she goes in that pool. Oh, that heated pool. That heated pool. So, Kirby, you grew up in Brisbane and you did your schooling here. What did you initially tend towards in your studies?

Guest Kirby Patterson-Fahy

Um, I was always very interested in maths and science. Um, and I decided quite early on in high school that I was interested in being an engineer. Um so I chose all the physics and the maths subjects, and yeah, I was really quite interested, planned my um degree to be an engineer.

Conversationalist Sarah Maxwell

So we know that something changed. So your educational track, when you seemed, like you said, quite sure that it would be mathematics and engineering, um, yeah, what changed it?

Guest Kirby Patterson-Fahy

Well, when I was in um grade 11, um my younger sister got quite sick um and was in hospital. And during that time, um I saw how many questions there were and how many um unknowns, and I became quite interested in medicine because before that point I had thought of medicine as something that had already been kind of set in stone, the answers were already quite known. Um, but then I realized like in medicine there's a whole heap of unknowns, and I was quite interested in um in that. So then I decided I was um gonna be a doctor.

Conversationalist Sarah Maxwell

Oh my gosh. Like, how many sisters and brothers do you have? I have three younger sisters. And so were you the only one that was becoming curious about your sister's like what was wrong with her and her um sickness?

Guest Kirby Patterson-Fahy

Yeah, well, I was the oldest, so I um was quite involved in in knowing what was going on, but I was also quite interested. So I like to to be there um when doctors were explaining things and really know what was happening.

Conversationalist Sarah Maxwell

And did you tell your parents that these thoughts were changing in you? Like that you were starting to think, hey, maybe not engineering, mom, like I'm actually thinking about medicine now.

Guest Kirby Patterson-Fahy

Yeah, yeah, I did. Um I yeah, I started talking to my parents um about being interested in medicine.

Conversationalist Sarah Maxwell

Yeah. And as your sister um, like in terms of being unwell, did your um passion and your drive shift even more as as her illness got worse?

Guest Kirby Patterson-Fahy

Yeah, so she was in hospital for um three to four months. So it was quite a long period of time. Um and at the beginning, I it it was I was more just interested in medicine in in became more interested in medicine in general. Um, but then as time went on was when I started really um being interested in what was going on for her and started, you know, researching online on um research articles and things like that and trying to understand um what was happening for her in her um mycobacterial infection. Um and yeah, when she passed away as well at the end was when um I really knew it was set in stone that that's what I wanted to be interested in, keep working with.

Conversationalist Sarah Maxwell

So are you saying that over those three, four months, so your sister passed away after four months? Yeah. Oh my god. Oh, Kirby. It's just uh when you first told me, I just couldn't even um, it was unexpected. I didn't expect

Losing A Sister And Seeking Answers

Conversationalist Sarah Maxwell

that to be the story. And so thank you for sharing it, first of all. And as that's happening, are you in some way trying to save her life?

Guest Kirby Patterson-Fahy

Not not really. The I knew that wasn't me. I was just a high school student. I wasn't going to do that. But I I was just really curious. I wouldn't understand what was going on. I didn't want to be um just you know watching and not knowing what was happening next. I really wanted to be knowing what was going on.

Conversationalist Sarah Maxwell

And as you were studying and looking and researching and trying to figure out this mycobacterium space, I I know you shared that someone in particular kept rising to the surface.

Guest Kirby Patterson-Fahy

Yeah, so when I was um researching, initially I was looking more at the treatment side of things, but then after she passed, I was um the question was where did she get this infection from? Um, and and you know, why why did it happen for her? And it was a big question, and the doctors had said, like, we'll probably never know the answer to that. And when I was looking um at research papers, I came across um Rachel Thompson's work, where she had found um Mycobacterium secessis in the tap water um in Brisbane. And to me, that then that made um sense. It was like, well, there's nothing we could have done to stop her from being exposed to tap water. If it's in the tap water, it's everywhere. Um that's wow, she's gotten she's she, you know, she's been exposed. Um somehow, whatever happened, it um she got sick from it from a lot of other people, but um, you know, it was inevitable that she was going to be exposed to it when we're interacting with tap water every day.

Conversationalist Sarah Maxwell

So am I to understand that you all everyone in the house was exposed to the same drinking water, and yet somehow your sister interacted differently with the mycobacterium?

Guest Kirby Patterson-Fahy

Well, it's it's really um hard to say what because um it wasn't like my tap water in particular or the household's tap water, but um, what Rachel's work has shown that you can grow Mycobacterium recessors from tap water. When we were in the hospital, the doctors had said, oh, you know, um, if you go to spas, sometimes they grow spas and people get sick from spas. And so then my parents were concerned about all the public swimming pools my sister had ever been in that she may have gotten it from there. But then with Rachel's work showing that she can grow it from various places of tap water in Brisbane, then it was, well, it was nowhere she went or nothing she did, it was just living where she did. Um that she must have been exposed to it somehow. Gosh.

Conversationalist Sarah Maxwell

I know we didn't plan on asking this, but does that make you feel vulnerable in general when you hear that?

Guest Kirby Patterson-Fahy

Um, not particularly, because like I know my um my sister had some underlying health conditions that made her slightly more vulnerable. I see. Um but it's like, well, you're exposed, everyone's exposed every day, and um only a certain number of people get sick from it. Yeah. So um that's an interesting research question of why do some people get sick and some people don't.

Conversationalist Sarah Maxwell

And I'm glad I wanted to say that because you know, all Brisbane people could all of a sudden not want to drink their water anymore. And yet that's why I mentioned that everyone in the house possibly drank the same water, and yet she had predispositions. Um, and that's what you're discovering in your research. So that was a long way of us discovering that Professor Rachel Thompson also is what introduced you to Gallipoli medical research, which we're gonna call GMR, um, today. So, so in reading about her, how did you actually meet her?

Guest Kirby Patterson-Fahy

So, yeah, I first read her paper about the the water um when I was in grade 12 in high school. Um, and then I started my Bachelor of Advanced Science knowing that I wanted to do some research and that I was interested in doing it there. Um and um throughout my degree I did a few different um kind of subject research projects, and then when it came to start um thinking about what I wanted to do for my honours year, that was you know going to be a whole year's project, um, and there was an opportunity to reach out to researchers and see if they would um do a project. And so I had um been reading more and more of what um Rachel and her group had been publishing, and so I sent an email to Rachel um towards the end of my third year of uni and said, any chance that um I could do an honours project with you because I'm really interested in the area.

Conversationalist Sarah Maxwell

Um and she replied, you tell her your full story at that time in the email? Not in the email. I thought that was a bit of a hard start. I know. I I I thought how did you handle that? So you didn't ask or tell her straight away how long you'd known her.

Guest Kirby Patterson-Fahy

No, so I um I said I had been quite interested in Mycobacteria and that I'd read a lot of her papers. Um, and then she invited me to come meet with her at GMR um to discuss it, options and projects, and yeah, I told her a bit more of the story then.

Conversationalist Sarah Maxwell

Amazing. So I guess we know from the intro that you ended up in her lab and you currently are still doing research alongside her, and at the same time, you're completing your medical degree, so and you're doing placements. Okay, so how do you manage all of that?

Guest Kirby Patterson-Fahy

Just gotta be really efficient and scheduling. Um, but I also just really enjoy um the research side of things, and so I just um try to fit in as much of it as I can.

Conversationalist Sarah Maxwell

And is it a common thing for so are your um fellow medical students doing research as well, or is this a unique kind of

Tap Water Findings And Joining GMR

Conversationalist Sarah Maxwell

career path that you're no, there's a few um medical students doing um research as well, um, but I'm not aware of anyone that I'm quite close to that is quite as interested or involved as I am at the moment. And is it something you have to choose between? Like, okay, I'm so interested in this mycobacterium, and I I'm gonna choose research, or can you continue to do the two things together?

Guest Kirby Patterson-Fahy

No, I can continue to do the two things together. It's um it's becoming more and more of a thing that people do, and it is what Rachel does as well. She does the two things together.

Conversationalist Sarah Maxwell

Okay, so she's a medical doctor and this research. Yes. Right. And do they have to converge in terms of topic? Like meaning, do you you become some sort of like specialist in this area as a medical doctor?

Guest Kirby Patterson-Fahy

Usually, because people usually have interests that that um coincide and they want to see the both sides of it, the clinical side and the research side.

Conversationalist Sarah Maxwell

Interesting. Okay, so we know that you said being organized is how you manage it, but how do you stay sane?

Guest Kirby Patterson-Fahy

That's where the swimming comes in.

Conversationalist Sarah Maxwell

Okay.

Guest Kirby Patterson-Fahy

Um, so yeah, I I like to swim as much as I can um in the mornings before I go. It's a really good start to the day.

Conversationalist Sarah Maxwell

What how would you describe the difference between so we just jokingly said you didn't swim today? Do you feel the difference between the days that you swim and the days that you don't?

Guest Kirby Patterson-Fahy

Yeah, I tend to get more things done on the days I do swim, but you do need a rest day every now and then.

Conversationalist Sarah Maxwell

So well said, well said. Um, that's so true, actually, because you can get a little bit attached to doing it all the time, but it sounds like you have a nice balance going on, which is not easy when you have so many demands on your time. So well done, you. Um, okay, so I understanding this clinical research in the lab, the interplay, right? And how it interplays with your medical rotations. Do you find that your unique background in some way defined you or makes you a little bit different as a medical student?

Guest Kirby Patterson-Fahy

I find I do have a little bit more um understanding of how some of the um guidelines and things in in clinical practice have come come about because I've um read about it on different stages of the in in different research articles, or have a bit more understanding in that way around um, you know, how it has come to be that, you know, this is a medication you use for this condition or this is what you do, um, which I think is quite valuable at times rather understanding the the why rather than just um following what what is done.

Conversationalist Sarah Maxwell

And in that same vein, is there a placement that you enjoy more because of that understanding?

Guest Kirby Patterson-Fahy

I've actually pretty much enjoyed all of my placements so far. Um and I'm still quite early on in rotating through all the different areas. Um, but it is really just relevant to everything because medicine really is built on research. Um I think in in historically it wasn't really recognized as such, but um all of medicine is built on research and evidence.

Conversationalist Sarah Maxwell

And what's your current rotation that you're doing? I'm doing pediatrics at the moment. Okay. Do you ever think about your sister more actually in this placement?

Guest Kirby Patterson-Fahy

Yeah, I have been. And I'm at the same hospital she was at because she was sick as well. Um, but it's been quite nice to be back in a different capacity and um yeah.

Conversationalist Sarah Maxwell

And do you emotionally, is that something you've um worked on

Balancing Medicine Research And Swimming

Conversationalist Sarah Maxwell

with your family in terms of like do you guys do something specific? Do you talk about her a lot? Is it sort of like no one's talking about it at home? Like, how does it work in your family?

Guest Kirby Patterson-Fahy

We talk about it a lot. Um, we talk about her a lot. Um, and she's you know still a big part of our family.

Conversationalist Sarah Maxwell

Yeah, that's beautiful. I notice when you share how many sisters that you have, that how you share that is really beautiful. I think that's a real um reminder um of someone's presence in your life. So yeah, um, we're learning from you as you share about her. Um, what was her name? Let's voice her.

Guest Kirby Patterson-Fahy

Um, her name was Anastasia, but we used to call her Taisie for short, because some of my younger sisters struggled with Anastasia. Because they're younger.

Conversationalist Sarah Maxwell

So, Kirby, I want to talk about you having two moms. And I just have a couple questions because I think this is a really unique part of your story. So I wanted to know are all of your siblings, so all your sisters, are you all from the same moms? Let's ask that first.

Guest Kirby Patterson-Fahy

Yeah, so um me and my next one down sister, um, we're both from the same biological background. Um, and then the two youngest um were foster placements um that ended up long term. So they both came out of hospital straight into our house as little babies and um was always going to be there the whole way through.

Conversationalist Sarah Maxwell

And were there any dramas when your sister got sick? Were there any dramas that maybe you don't know the it's okay if you don't know the answer, but were there any in the movies you see dramas medically with um same-sex parents? Was there anything of that nature that happened in the hospital setting or anything like that for your moms? Definitely not that I was aware of. Um so, in general, um, I mean, you don't know any different, right? So um just like my daughter has two moms, you had two moms, so and I don't think she knows any different either. But do you feel that let's go for what are some of the benefits of having two moms? I think there's lots of benefits.

Guest Kirby Patterson-Fahy

I think I would agree. I think I've had uh a great time with with two mums. Yeah, um, I think that there's a lot of freedom with it. I think with my with two mums not being fixed on the this is what a dad should do and this is what a mum should do, that it's really um balanced who does what and a lot of like cohesion because there's no there's no expectations, it's just um two people who really love each other, you know, um getting things going um and doing what needs to be done. Um and it's been um a lot of great connections with other people as well because they have some really really good friendships within the LGBTQ. Yeah, got it um and new a unique perspective as well on on life and what makes a family, because I think a lot of people get really hung up on biology. Um, and for me that's something that like especially with seeing you know my two younger sisters having no biological relationship to us at all and how we all work as a family, um, you know, four sisters and and the two mums, regardless of biological connection.

Conversationalist Sarah Maxwell

Oh, beautifully said, and yes, I'm seeing a lot of females in that house. Uh as you said that, it's so true. But thank you for sharing that unique perspective that's special for your life, you know, and and we could go, we could do a whole podcast on on this topic, but thank you for mentioning that to round out your experience. And even when I think about you in a lab, what you do for work, it's another feature to the amazing things you do. So thank you very much for sharing that part of you. What specifically are you currently passionate about in your work and study? Because I think there's been a little bit of a morphing.

Guest Kirby Patterson-Fahy

Yeah, so initially I was just really interested in um, you know, Taisie's infection and and her experience with mycobacteria. Um, but then reading more about it, I realized that it's it's uncommon, but there are a lot of people that get really sick um with mycobacterial

Two Mums Foster Family And Belonging

Guest Kirby Patterson-Fahy

infections, and a lot of people that um end up trying to treat them for a really long time with different degrees of success and often not a lot of success in in actually treating and clearing the infection. Um so more recently I've been um doing some lab work on new antibiotics um combinations that can be used to treat mycobacterial infections.

Conversationalist Sarah Maxwell

Okay, I'm kind of interested in this. There's a personal um interest, but I think it's what you just said, not realizing that this, that there's a possibility that you can have an infection that they cannot identify. And so when you talk about new antibiotics, um is that what the limitation is, that it's a bacteria that has not been seen before, so they just don't have any match to fight it?

Guest Kirby Patterson-Fahy

Yeah, so the the biggest limitation with mycobacteria is they're they um have a quite unique like cell wall and structure around them that even if the the targets for antibiotics exist that already around and use in other infections are there inside the bacteria, they have this really um heavy guard of coating around them. A lot of antibiotics don't get in. Um, so it's it's really that's the challenge is um it's just really protecting itself and it does a really good job of that, and it's really hard to get anything in there to kill it.

Conversationalist Sarah Maxwell

So basically, the more popular antibiotics that we know about, are they more like broad spectrum? They're trying to like go after a host of bacterium. And the word myco that we're adding to it, is that a specific strain, or is it all myco? This is the layman's question.

Guest Kirby Patterson-Fahy

It's a very good question. So the the myco means um it comes from like fungi as. fungi fungi like um that that's what they look like on a on a plate and it's part of the the the extra hard coating around the outside is is the bit that makes them the the mycobacteria and there's like 250 species of mycobacteria themselves um and one of which is tuberculosis so that's why it's called non-tuberculous mycobacteria sometimes the area I'm quite interested in um and yeah does that answer the question no it does and it well a couple things I'm thinking you are in the right field at the right time is what I'm thinking um because are when you just named the 250 did you say strains I don't know if you say species sorry um are those new discoveries or are they they're always going to be 250 strains or species yeah so they're there the new species have been identified and kind of added to the group over time and some of them were originally thought to be the same thing but as our um detection methods have improved we've been able to split um some of them out and identify them differently um which is um and all those 250 not all of them cause disease as well there's only a few a subset that cause um like quite significant disease yeah um although yeah and so if you have um now I'm asking a lot of these questions but if you is there an antibiotic for each species of the 250 um mycobacterium that you've just said yeah so the environmental ones that don't cause disease we haven't really been looked at because you don't don't need to worry about antibiotics for those um and then the handful that do cause clinical disease they um all have kind of different combinations of antibiotics that work for them and slightly different susceptibility um profiles and is the

Why Mycobacteria Resist Antibiotics

Guest Kirby Patterson-Fahy

only way to get rid of them through an antibiotic yeah and usually it's more than one lots so they um for a standard treatment for a pulmonary um NTM infection is you know a year of antibiotics and usually um you know at least three at a time a year yeah oh my gosh okay that's a long time okay so thank you for that because I feel that's going to be the the patient um interest in mycobacterium you know and now you're at the solving end of things which is very interesting um when you go to conferences like you know we mentioned you know in Washington in 2023 that was the thoracic society then you go to the Mycobacterium one in Colorado recently what do you learn there? Like how does this actually impact your future career path yeah I've really enjoyed um the two conferences that I've been able to are international overseas ones I've gone to um and there's just such a wealth of different um people all interested in different aspects of it and they're all coming at it from slightly different angles different specialties of medicine or um of different branches of science and they all come with their unique approach so it's really interesting to see all the different ways that people are looking at this and all the different angles they're coming from and to see that there's so many different ways that I could go in the future.

Conversationalist Sarah Maxwell

Do you have a vision of so far of where you want to go in your own career?

Guest Kirby Patterson-Fahy

I don't have a specific vision so far. I know I really want to keep doing research and um I'm gonna stick with the mycobacteria at the moment because that's what really interests me at the moment but I'm haven't experienced all the the medicine side of things yet or the placements um and to know what that's like on a on a day-to-day and actually working in the field. So I'm really excited to you know try out all the different things first and and see where it leads me.

Conversationalist Sarah Maxwell

And what are you due to graduate from your med degree?

Guest Kirby Patterson-Fahy

So I'll graduate at the end of 2026. Okay so next year you graduate and then you specialize? And then I've start an internship which is two years of like on the job training where I'll rotate again through different um areas of the hospital.

Conversationalist Sarah Maxwell

Incredible yeah it's really interesting hearing the the connection to the research like you said all medicine is based on that research and and sounds like you are really connected to that fact because of how things have gone for you so far. So another um shout out to your sister and how she's complimented what you're doing in that way.

Guest Kirby Patterson-Fahy

So if we take stock of your current academic life all the things that you've seen at these conferences if you could wave a magic wand what would be your ultimate job yeah I'm not sure um I know I definitely want to have a job where I have time to do research. And that's built into it but um what I've seen from the conferences as well is a lot of people kind of build their own jobs using their own combination of clinical practice as being a doctor and research. So something that involves you know seeing patients interacting with patients, helping patients and their families and something that involves um a good balance of research as well.

Conversationalist Sarah Maxwell

Yeah thank you for mentioning that last part because I think that's what I was curious about is could you work in a lab with no one there or is it really about interplay with the patient and their family? So now I get it that that's a really critical part of it for you. And I think what's been really interesting is just hearing how your life experiences and what you've gone through as a family has really impacted your passion and your focus. But even how it's still it's still happening you know whether it's your supervisors and the professors like I can see that it's still forming for you. So I think it's a really interesting dynamic to follow your life this way.

Guest Kirby Patterson-Fahy

Now if you were to I don't know not word coach but give advice to a grade 11 grade 12 student about this area what would you what would your advice be for them if they

Conferences Career Vision And Advice

Guest Kirby Patterson-Fahy

are interested in some of the things you are just don't be afraid to send an email to the person you've been reading about because um you know that's what started it and if I had been scared to to write that email and along the way in the research um during my degree there was a few other opportunities where I asked someone you know can I spend um you know six weeks over summer break learning some of the lab skills um that built me up maybe ready for the for the honors um I think yeah you've just got to don't be scared to reach out reach out and ask good advice Kirby so quite well actually were you scared but you did it anyway or you actually never questioned it?

Conversationalist Sarah Maxwell

I was scared and you did it anyway. And you did it anyway. That is fantastic advice you're right because in your story when I heard that I did think oh that's no small potatoes to read about the person who's at the forefront of the work and then to contact them. That's yeah okay that's a that's fantastic advice and so you've heard it here everyone Kirby is telling you that that can change the trajectory of your academic life and probably going to be your your future medical life. So I just want to thank you on behalf of like GMR and the community because the you really are making an impact by the time that you devote to research and it does make a difference. So I just on behalf of all of them I just wanted to say thank you for not only the work that you do every day in the lab but also for coming and sharing it with other people that makes a difference. Thank you.

Host Miriam Kent

Thank you for joining us for this episode of Voices. We hope you've been inspired by the courage honesty and generous spirit shared on today's episode our work only happens with your support so please visit us at www.galiferesearch.com.au and now over to your part if you know someone who needs to hear this episode please share it with them and why not review our podcast so that others can hear voices of GMR don't forget to click the follow button so you can easily find that next episode thank you for listening we look forward to sharing the next voice of Gallipoli Medical Research with you very soon

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Miriam Kent (CEO Gallipoli Medical Research)

Host