The Peptide Episode

In this episode of Double Booked Official Podcast we sit down with peptide and wellness expert Lisa Esposito to break down everything you've already been googling about peptides, wellness, metabolism, and aging. 

• We talk about:
• What Peptides are
• Why they're everywhere
• Who would benefit 
• How to get the right ones

Whether you're simply curious or hearing about peptides for the first time, the conversation was designed to break down all the details and share how to connect with Lisa directly to begin your peptide journey. 

Transcript

SPEAKER_01 0:00

Double booked official podcast. Today, for the very first time, we have a special guest. We have Lisa Esposito, a nurse practitioner based in Tampa, Florida, by the handle of Lisa Marie Wellness on Instagram. Lisa has built her entire practice around something that most conventional medicine is just starting to pay attention to, peptide therapy for women. Lisa works at the cutting edge of women's health, helping her patients optimize everything from hormones and body composition to energy, recovery, and longevity using targeted peptide protocols tailored specifically to how the female body works. If you've been curious about peptides and what they can actually do for you, or if you've felt the standard answers just aren't cutting it, this conversation is for you. Lisa, welcome to the show.

SPEAKER_00 0:53

That was a great introduction.

SPEAKER_01 0:55

Well, listen, I'm not gonna, yeah, right. I'm not gonna lie. I actually chatted some of that and I'm like, oh wow, this sounds really, really good. I'm gonna keep, I'm gonna have to chat all my uh opening sentence. I love this from here on out. That was great.

SPEAKER_00 1:09

That was I can I hope I can own up to that. I mean, that would be a good idea. That's pretty impressive.

SPEAKER_02 1:15

You definitely can. I'm so, so excited for this topic. I I really love, and I have a question for both of you. Lately, it feels like we're finally reaching this intersection between beauty and aesthetics to actual wellness. Is this really like a new thing that's happening? Or am I just in the age where now it's relevant to me? So social media is now bombarding me, or is this new that we're talking about wellness instead of just beauty at any price?

SPEAKER_00 1:47

No, I think absolutely that's the way this industry is trending. You know, being in the aesthetics industry and having been in the aesthetics industry for several years now, I can I've seen a change over the last, I would say like two to three years. But this past year, I feel like things really ramped up. But definitely looking at things internally more so than just looking at the exterior. You know, if you can look great on the outside, but if you're not functioning well internally, you're that reflects on the outside as well.

SPEAKER_01 2:15

So have these have these been around and we just didn't know that how to utilize them, or it like right? Because for a while it was like the skincare regimen and the and the moisturizer and this, and then now all of a sudden you can inject almost anything and it's like, oh, you'll be younger, you'll be this.

SPEAKER_00 2:32

So it has this been going around or yeah, I mean, peptides have been around and have been used for a long time. They were more commonly used in like the fitness industry for probably a couple decades now. So people in like fitness, bodybuilding, things of that nature had been using these for a while. But, you know, I think the GLP one is a gateway, right? I don't want to call it a fad because it's not a fad. I think it's here to stay forever. But I think that was like when it kind of started to normalize that kind of care where you're doing things more on your own and doing it not just for weight loss, but for wellness as well. So I think that kind of, like you said, truly was the gateway. You know, people got comfortable with injecting themselves at home. And that just kind of opened up the doors to other things and taking control of our health and not relying on I don't want to go into that in much depth. But yeah, topical, but also just medicine in the way it's practiced now. And I think that, you know, I don't want to go too deep into this and go down this rabbit hole, but I think that a lot of medicine, like your family medicine doctors, their hands are kind of tied in what they can do because they're having to work at the like the expense of the insurance company. So they're living in the city.

SPEAKER_02 4:00

But I don't think that there's a big focus on on getting wellness. Yeah, there's a very big focus on the profit center. I also doubt, but yeah, exactly.

SPEAKER_00 4:10

Yeah, like I don't know if we want to get into that, but but no, it's it's really it's been great to see just people wanting to take control of their health and not just wait until they're told they have to go on a blood pressure medication or cholesterol medication or you know, things of that nature.

SPEAKER_02 4:27

So it's yeah, my dad is a very he fancies himself a biohacker. He is all the way down the rabbit hole. He's obsessed with peptides. He's been studying them for probably six or seven years. He believes if there was less regulation in the studying of peptides, that they could fundamentally change the entire healthcare system, be it in America or or everywhere. And there's other countries that he thinks are so much further ahead, some European countries, Mexico, things like that, that really like peptides could change whatever we know. So the fact that we even get this small portion of it, and the portion that we do get is of course related to our vanity, is still very exciting. I'm so excited for this. Yeah, no, it is very exciting. If a patient comes in to you, I assume, and I and you can tell me I'm wrong, that a lot of your patients are are women and that they are generally they have maybe a kid or a few kids, and all of a sudden, age is starting to happen in some way or another. What are their chief complaints?

SPEAKER_00 5:33

Generally, weight gain is like the the number one thing that I feel. Weight gain and fatigue are probably the two biggest things that bring people in to see me. But that, you know, weight gain, especially around the midsection, fatigue, brain fog, loss of libido. I mean, there's lots of hair, skin quality changes. There's so many things. And, you know, it's not, they're not always coming into me for a wellness or peptide consult. They may be coming into me for something aesthetics, like maybe an injectable or Botox, but it opens up the conversation to, you know, like we can only do so much externally. And I always tell people like 80% of what like your aesthetic care, like 20% of it's what we do in the spa, and then 80% of it is what you do at home. So you can only do so much Botox and fillers, but if you're not taking care of yourself at home, and that means like skincare, your diet, exercise, nutrition, like all of that plays such a big role in how we look on the outside.

SPEAKER_01 6:36

So so then how in incorporating peptides into the conversation, how what do you tell them peptides are? And how do you explain it to, you know, somebody who has never really heard or tried it before?

SPEAKER_00 6:48

Yeah. So peptides are naturally occurring, they're chains of amino acids. So you've heard of like amino acid powders that people take, like BCAAs, like those are chains of amino acids, but peptides are just a little bit more specific and they are designed to perform a certain function in your body. So we all have peptides circulating in our bodies now, and like I said, naturally occurring. So it's not the same as taking like a synthetic hormone or a synthetic, like like you've heard of people taking like growth hormone, like it's not the same or HCG. It's it's it's almost like the precursor of that. So it's signaling your body to perform a certain function that as we age, it may not be performing as well as it did when we were younger. So it's it's very interesting. And you know, I think that it's going to be really interesting to see how health, like healthcare trends now, like having these tools and them becoming more widely used and accepted in our industry.

SPEAKER_02 7:47

So is there an I did chat GPT what a peptide is to, and I said explain it to me, like a five-year-old. And it said that essentially amino acids are individual Legos, peptides are like the little bag of a subset that you put together, a few pieces of those Legos, and then proteins are the entire thing that you created out of the Lego. So they're like the building blocks of protein.

SPEAKER_01 8:10

So that's what I think. Is there an age that you're gonna see? It you know, is it the 40-year-old woman? Is it 50-year-old man? Like, what is the age? Is there an exact age or a roundabout age? And when you start should start doing this, is it something you should start doing when you're younger?

SPEAKER_00 8:28

No, I think it's very, it's very subjective. So everybody, you know, tends to experience these symptoms at different varying ages. So I would say on average, population that I see starts around like mid-30s to you know, upwards to 40s and 50s for women and then men. I don't see a huge male population. I'm hoping to increase that here in the coming months. But I would say a good majority of the men that I see are, I see their spouses and they're they see how amazing their spouses are looking and feeling. So they're then interested in it as well. But like I said, it's very subjective. Like I have a couple 20-year-olds that are taking some, like it just, it really just depends.

SPEAKER_02 9:14

Like so whether hook it up. Like if you like obviously GLP1 starts with weight loss, but other things like NAT and other different peptides, if you didn't start that to your 40s, can you catch up to feel optimized? Or is it like, hey, look, there's gonna be a period that's just lost and this is just the best you're gonna feel?

SPEAKER_00 9:35

No, not necessarily. I would say, like, if you're coming into me and you're 40 and you've never had your hormones looked at, that's gonna be where we start. So before we I always tell my patients, like, let's optimize your hormones, your thyroid, all of that needs to be functioning because otherwise we can give you a peptide, but that's like putting a band-aid on it. And I'd rather fix the root problem, which a lot of times, if our hormones are not optimized, then you know, I think that a lot of times fixes the issues that people have. But that's not to say peptides can't also be layered in there and help, you know, with energy and other concerns that you have as you're entering that perimenopause age.

SPEAKER_02 10:17

So, what would be like your baseline tests? So they come in, they're tired, they're gaining weight, they're just feeling older. What are the tests that you're gonna order kind of step one?

SPEAKER_00 10:27

So if you've come in and you've you've already been treated for your hormones, you're getting pellets or you're taking, you know, getting using creams or whatever. So that's already that component's already been addressed. It just depends on which peptide you're wanting to move forward with or what I guess what your chief complaint is. Now, if it's weight gain and we're wanting to start on a GLP one, I usually just order a very basic panel of labs just to check and make sure everything's functioning well and get a baseline before we get started. If you've had it, I tell people within the last six months. So if you've seen your primary care physician, we can use those labs and go based off of that. But if not, we can, I have the ability to order it and just go to any quest and get those labs done. But it just depends. Like I don't order labs for NAD. There's certain peptides that I just don't feel the need to order labs for. And so it just depends on which ones we're going with.

SPEAKER_02 11:18

But what if you haven't had your hormones addressed? Like what kind of a what should they be looking at for the hormones?

SPEAKER_00 11:25

Yeah. So I would we would do a comprehensive hormone panel, which includes everything from your thyroid function, your vitamin D, your vitamin B12, your all of your hormones. So your your FSH, your estrogen, your testosterone, your free testosterone, like it's pretty extensive comprehensive panel that we do. Yeah.

SPEAKER_01 11:45

Yeah, I've had it done. And both my husband and I have had it done. And so we both are on different in injectables. So I've done um a semaglutide. I have an NAD, which I'll be honest with you, I don't even know what the NAD does. So that I've got a lot of questions around that. Uh, I've done a B12, which I feel amazing with B12. I think it's like the answer to my brain fog and afternoon energy instead of a coffee. Um so I I would tell you it's like a great process to go to through my gland. And it's I had no idea. I still don't have an idea. There's so many probably other components and other peptides I should be taking or mixing in or what have you.

SPEAKER_02 12:28

So I'll have to tell us what some of the peptides are. Like, obviously, I think we know about semiglutide or GLP1 person, but but pretend we didn't. Just tell us like what's the range? What are these peptides?

SPEAKER_00 12:41

I mean, we have peptides. I mean, there are peptides that, like I said, I think complaints that I hear are, you know, weight loss or weight gain, fatigue, brain fog, immune system. Like, let's say it's a teacher or somebody who travels a lot, that they just are constantly coming down with something. People with autoimmune concerns come to me looking for help with inflammation. We have peptides that are great for recovery. Like if you've had an injury and they can just help you to get back on your feet quicker. Oh my god, these are so exciting.

SPEAKER_02 13:12

I need all of that.

SPEAKER_01 13:13

There's so many things. What's the one, Michael Ann, that you put on your face? Chrome? Copper copper. I use copper.

SPEAKER_02 13:21

Topically, and I love, I feel a big difference. And I've done NAD. I don't know that I saw a big difference using, but again, it could have been the wrong one. But I also I love glutathione. I love it. I love it. Obsessed.

SPEAKER_01 13:36

What is that?

SPEAKER_00 13:38

So glutathione's your it's a your body's master antioxidant. So I like that one as like it's like the bread and butter of any kind of wellness protocol. So that energy and the GLP one are my staples.

SPEAKER_02 13:52

I I noticed a big difference. Like, I feel like as I got older and into menopause, so I had a hysterectomy, so I went straight into full-blown menopause overnight. But like, you know how when you suddenly can't drink anymore, like you have one glass of wine, you wake up the next day very foggy and hungover feeling. And if I'm using the glutathione regularly, that sort of eliminates that to a large degree. I really notice it in that tangible way.

SPEAKER_00 14:17

Yeah, yeah. Well, it's helping with detoxing. So I tell people like, if you've had a night out drinking, like give yourself a double shot of glutathione and you'll be okay. That's not the purpose that I like. That's not primarily why I prescribe it, but it's just great for overall like wellness and vitality. You know, it helps with like mold, metal toxicity. I feel like living in Florida, we all probably exposure mold every day. So it's just it just it's like purifying your body in a way.

SPEAKER_01 14:44

Is it a is it an oral pill or is it injectable?

SPEAKER_00 14:48

So we have injectable, it is intramuscular. You can inject it under the skin like you would your GLP1, but it just it takes a while to absorb and it burns quite a bit. So we typically recommend in in the muscle. So I do it to myself in my glute, which is really fun. But yeah, but there are some really great like oral forms of it. You just want to make sure it's like a liposomal version that is pretty well absorbed. Injectable is gonna be the best absorbed, but you know, the liposomal versions are great too.

SPEAKER_01 15:21

I think it's funny. I did inject my husband a few times before he got used to doing it himself, or I wasn't here, so we had to do it on his own. And you know, the needles are so tiny on some of these. I'm like, he goes, You've already already done. And I was like, Yes, it's like a baby needle, like it's nothing at all.

SPEAKER_02 15:38

My husband's out on that. He's out on anything to do with needles. We also like, he's a little bit older than I am, and we've been recently kind of having this two sides of the conversation. Like, he wants to go to a traditional doctor. So when he is tired, when he is feeling age, when he is gaining weight, when he feels like he has age spots on his face, he wants to go to a traditional regular MD family practitioner. And then he comes home and he doesn't understand why his problem wasn't solved. And I keep trying to tell him, look, you have to go to somebody who has more of a concentration in non-traditional medicine, has access to that, and also is going to have sort of that aesthetic and like beauty vanity component to it because they're just gonna be willing to stretch further. Like your doctor's like, yeah, I know how to do one thing and one thing only. And if it's not, you know, and something like you throw penicillin on, I'm out of ideas.

SPEAKER_03 16:33

And so he's just very referring, we're for you.

SPEAKER_02 16:37

Yeah, he went to like he went to a dermatologist because he had this like age spot, and they like took a chunk of it and biopsied it, and it was fine. But he's like, Well, I still have the age spot, except now just a piece is missing. And I'm like, Yeah, you went for the wrong goal to the wrong place.

SPEAKER_00 16:53

Yeah, no, and there are some great dermatology offices that are more aesthetic foc focused, but those are I feel like oh yeah, what are what are your so you mentioned?

SPEAKER_01 17:07

I can't even say the word you mentioned, gloyula foil. So you had glutathione. Is that and semiglutide or GLP1? Those are your top two peptides that you use. What's kind of a what's a third that you think is pretty hot right now that you'd see?

SPEAKER_00 17:25

I would say NAD Plus and GLP1s are the top two. I always like tell people those are my bread and butter. Like those are the two I'll never be without. Even a GLP1 in a patient that's not necessarily looking for weight loss. I feel like most women benefit from it just for like the inflammation benefit that you receive. Like I personally microdose, like I'm not on a dose that's you know, I'm trying to lose weight on. It's just more for inflammation.

SPEAKER_02 17:52

And I don't take a dose every week, I take a very small dose every two weeks, and it just helps a great deal with my inflammation and um insulin resistance too, because I feel like you get the menopause, you start to become insulin resistant, even if you never reach like diabetic or pre-diabetic levels, you really are still having this insulin resistance.

SPEAKER_00 18:12

Right. Yeah, no, I think there's still so much to come with GLP1s and studies that are going to show so many other benefits that I feel like we don't even know half of it at this point. But can you take these things forever?

unknown 18:26

Yeah.

SPEAKER_00 18:27

I mean, people are on insulin forever, people are on metformin forever, you know, it's it's not going to be harmful to you, provided you're not on a, you know, if you're healthy and you're taking it at a very small dose just for like the inflammator, inflammation benefits of it, it's safe to be on long term.

SPEAKER_02 18:45

Yeah, I think back to like in the early 2000s when like hormone therapy first started becoming more popular. And there was that study done that said, hey, look, estrogen causes breast cancer, you shouldn't take it. And so so many people that reached menopause in that generation never started it. And now, of course, just in last year, 2025, the FDA finally came out and said, look, those studies were incorrect, short-sighted, and not accurate and highly, highly safe. But there's still a large school of people, doctors, that say, look, you can only do this until you're 60s, and then you got to get off the hormone therapy. I have no intention of like aging at 60 either, for the record.

SPEAKER_00 19:28

I literally, I'm so passionate about this that I just got goosebumps, like just hearing you talk about it, because it is it's so insane how like basically women were told no, you can't do hormones. And now it's like we're trying to recover and fix all of the damage that was done because of that study, which was totally debunked, more or less. Um, and now it's like we're having to go back and reverse that damage. And there's still so many old practitioners that are like, nope, no hormones for you, like you're tired, like that's normal part of perimetopause, like you'll be fine, like that's all normal. Like just reassuring you that these awful symptoms are normal and you just need to put up with it because you're a woman and this is this is what happens. But because they were told at one time that there's this black box warning on these hormones, and women can't have them. And it's like it's it's so frustrating. And I went away for this really great hormone training two months ago, and they talked a lot about just that generation of women that did not use hormones because they were told no, you cannot because of this black box warning, and how the increase in Alzheimer's dementia is insane in that age population and all of these memory care units, it's like that generation of women that's that's who's suffering. So I'm just really hoping that now with that being lifted and hormones becoming at, you know, the front of this conversation with wellness and health for women, that hopefully we can prevent a lot of this going forward. Yeah. Are you seeing there?

SPEAKER_01 21:05

Are you seeing and hearing a lot of the benefits with hormones, you mean? Yes.

SPEAKER_00 21:13

Absolutely, yeah. It's I feel like I prior to going to this training, like I've always been a big believer in like hormone optimization optimization, thyroid optimization, but this training was like really eye-opening to me and just uh the statistics showing just how bad it got with that population of women that were told, like, no, this is not safe. You know, you're gonna get cancer if you do this. Like, and there were still people that used them, it just wasn't as widely accepted. And your OBGYN wasn't offering them, you know, you couldn't go, it was hard to access. Whereas now I think it's a lot easier to find access to hormones for women, especially.

SPEAKER_02 21:53

Yeah, but my mom, so my mom is in her six, she's mid sixties, and She was in that generation that was told you can't you can't take it. It's not safe. And and even now, where you know, I've explained to her the studies show that it's is safe. Her doctors are still telling her, Well, yes, it is safe, but now you're too old. Now you can't do it now. You can't start at 60. And I'm like, Mom, you you still have call it another 40 years of life. Don't you want it to be the best? And she will think back to that late 40s when she was in menopause as still like a dividing line to her history. Like she feels like things just switched off and went downhill and she gained all the weight and she can still type.

SPEAKER_00 22:39

I know it's heartbreaking. Yes, I mean she's not too old to start hormones at this time. Yes, it is ideal to start when you're entering perimenopause. Like that is the window that you really want to get on hormones if you're having hormone imbalances, but it's definitely not too late. She could she could feel better than she feels now, for sure.

SPEAKER_02 22:58

Yeah, I agree. I tell all my friends, I and this is true for anybody, for everybody should feel this way. I am not interested in just feeling a little better. I am interested in optimized. I'm not I'm not giving up. I will never accept, like, hey, now you're whatever age you are, you just can't go up and down the stairs as well. You just gotta slow down. You just it's okay to be forgetful. I refuse. I'm not gonna do that.

SPEAKER_01 23:25

No way. I can't do that.

SPEAKER_00 23:28

It's time we take control. It's like I feel like we've been held back as women for so long, and men are have been getting their testosterone for years. They feel great, it's our turn.

SPEAKER_02 23:38

Yeah, like they've been getting testosterone when it comes to like ED medications, they're all covered by insurance, they're all available for the slightest provocation, but we have to fight for the right to pay cash for bioidentical hormones to get us to feel good. It's ridiculous. It is and we have to convince people that these are real symptoms and we're not just losing our minds.

SPEAKER_00 24:03

Or that, yes, they're real symptoms, but I don't have to accept it as like this is my life from now on. Like there's a treatment for it, and I deserve that treatment. I I want to feel good, and that's I think that's where we're headed, and I'm really excited about it because it's enough enough. It's time for it's our time to shine. Yeah, they don't want us, they don't want us to be powerful.

SPEAKER_01 24:26

So, what's what's next in all this in the peptide research and what's coming to the table? Like, you know, we've heard of of some of these things helping with ADD and other aspects of like you just mentioned with your health. But what's next? What are they going to, what are they looking at? What are we reviewing? What can we expect maybe coming down the pipeline?

SPEAKER_00 24:49

Sure. So there's been a lot of red tape around surrounding peptides. And I'm sure if you're interested in peptides, you've done research on peptides, you know that there's some FDA stuff going on with peptides. Dozens of them were put on this FDA do not compound list, which made it really hard to acquire these peptides. So people started going the gray market avenue, which is not always safe. Those peptides are not well regulated. They may not be sterile, they may have endotoxins in them. Like you just don't know where they're coming from and what you're putting in your body. So it was really scary times that you know, people were just taking these peptides that they're buying off the internet with no medical oversight and injecting them. And, you know, there was a lot of instances where people had some really bad outcomes with that stuff. So I think as a result, in seeing this all kind of happen, our government is kind of wanting to revisit that and maybe try and offer some of these peptides or allow compounding pharmacies to be able to produce them. So dozen, I think a dozen or more of them were removed from this do not compound list, and they're on this like level two or category two list where technically they can be compounded FDA regulated compounding pharmacies. So my practice, I only use FDA-regulated pharmacies. So they're 503A and 503B registered pharmacies. If you're getting into peptides, you want to start using peptides, and you're not going to be, just make sure you're doing your research and whoever you're seeing, whoever whatever provider you're seeing, you're verifying that they're getting their peptides from a 503A or 503B pharmacy. That's going to be the safest avenue. They're checked for because they're FDA registered or regulated, they have to go through a series of testing for sterility, potency, purity, as well as like endotoxin testing. So you know that you're getting the safest, cleanest, purest peptides out there. So, yes, there's a lot going on in that industry. And as far as like regulation goes, I'm hoping that there's more to come with that and that you know, there's more access for people to get it the safer way, as opposed to going the research avenue.

SPEAKER_02 27:08

What do you tell people about some of the side more common side effects with like the GLP ones about the nausea, the not eating? Like, how do they support that or overcome that?

SPEAKER_00 27:18

Yeah, so at my practice, we offer both semaglutide and terzepatide. I would say 99% of my patients are using terzepatide over semaglutide. I just feel that the quality of the medication is significantly better. The side effect profile is way less than semaglutide. And I do feel that my clients that are wanting to lose weight on the trasepatide have less muscle loss. And I think with the semaglutide, people experience more of that nausea and just total aversion to food where they just can't even bring themselves to eat anything, let alone the protein and meet their protein requirements, so that they don't lose muscle. Whereas trzepatide, you don't really experience it, at least not to the degree that you do with semaglutide. So you're able to eat a more balanced diet and get your protein, meet your protein goals so that you're not experiencing that muscle loss. So generally, I try and, you know, tell people that trusepatite is going to be the better option for side effects. At smaller doses, most patients don't experience any side effects. If they do, it might be that first, first or second injection. So the first or second week. I always tell people that first injection, you want to bump up your fluid intake. So day before, day of the injection, a couple days after, your body's gonna do some adjusting. So you might experience a mild headache, a little bit of fatigue. But if you're getting enough fluids, I always tell people like add an electrolyte powder in there too, or electrolyte drink. I think that really helps kind of combat some of those side effects there. But like I said, smaller doses generally don't experience too many side effects, if any at all. As we get up into higher doses, if it's somebody who is more insulin resistance and require resistant and requires more of the medication, then we talk about ways to manage side effects, which oftentimes is like constipation, sometimes nausea, reflux. Those are I'd say the biggest three that I hear. So we just talk about ways to combat those. Do you have like specific questions about any of those side effects, or was it just kind of just in general?

SPEAKER_02 29:27

And then if you if you are down to call it your last 10 to 15 pounds from your goal weight, are you still eligible for the GLP ones?

SPEAKER_00 29:36

Your 10 to 15 from your goal weight, you said?

SPEAKER_02 29:39

Yeah. So you get the last five to 10 pounds. Maybe you have you, maybe you've never done a GLP one and you've just kind of fought and fought and you're down to like those last 10-ish pounds. Are you still eligible? Is that still a good idea?

SPEAKER_00 29:52

Absolutely. Like that's like my ideal patient is the patient that's exhausted all other efforts and now they're they're looking for a little help. I would rather that than somebody come in who has 70 pounds to lose and wants to take trosepatite and do nothing else because that's not gonna work. Like you're gonna lose the weight, but as soon as you stop it, you're gonna gain right back. So my ideal patient is somebody who's coming to me because they're frustrated because they've they've been working out five days a week. They have a personal trainer, they're eating all the right things, but they can't seem to the scale's not moving. That's you know, my ideal patient.

SPEAKER_01 30:25

So it was a game changer for our whole uh most of our family. Like I did it, then my husband did it, my parents did it. Like it's it has been a game changer, especially that last like you said, last 10. I think I think I was at probably 15 to 20 pounds that I needed gone, and it came off slow and steady, and it hasn't I microdose as well. So yeah, it's um I'm at the same as when I got to like my so-called goal weight. And and and it made me just feel uh better and a lot more a lot more confident in myself.

SPEAKER_00 31:01

Yeah, no, it's great. I mean, it's I I can't like speak highly enough of it. Like it's just I feel like helps so many people, and just I've seen so many people's lives literally change, just from you know, getting to a healthy weight and having a little help with some GLB1s, yeah, you know, provided you're making those lifestyle changes. Yeah, yeah, confidence is huge.

SPEAKER_01 31:24

Yeah, definitely. So going back to the NADs, what is that supposed to do? Because I have it, I've taken it. Like, what am I supposed to be seeing?

SPEAKER_00 31:33

So NAD is a it's actually not a peptide, which a lot of people think it is. It's always grouped in with you know, wellness protocols, people call it a peptide. I often sometimes even group it in with peptides, but it's a coenzyme, so it's something that's inside of every cell in your body, and its job is to provide fuel and energy to your mitochondria, which is mitochondria of the cell is like the battery of your cell. And so NAD goes in there and helps pump it up a little bit more, give it more energy so your cells work more efficiently, repair themselves better. And just so NED, when you're giving yourself an injection of it, is going to help every cell in your body run and work more efficiently. So I like it as like you're it's like you're all-encompassing. Like if somebody's coming to me with just like really generalized, like vague complaints where it's like everything, like I'm tired, I'm just not recovering from workouts, I have like get sick every other week and all these things. Like I oftentimes will start with NAD just because it's gonna go in and repair your cells and help yourselves to work more efficiently. And it's gonna be your immune cells, your, you know, your skin cells, everything. Everything's just gonna work more efficiently. Now, if you're not taking an appropriate dose, you may not be seeing or feeling the effects of it. So that's something you and I could chat about. Yeah, make sure that you're on an appropriate dose because you know, a 30-year-old may not need as much as a 40 or 50 year old. And so I have, you know, patients in their late 20s that are on it and they're on a small dose because what happens is as we age, it's something we have a lot of when we're born in our 20s. In our 30s, it starts to drop off. I think in our 40s, it's dropped off by about 50%. If you had zero NAD in your body, you would not be living. Like you need it to live. So, you know, somebody who's younger may not require as much as somebody who's in their 40s or 50s. So it's very subjective in, you know, whether or not you're getting relief by taking it. So it's something we could chat about, but it is something it's not always immediate. It's might be building up because if your NAD level is very low, you're gonna need a little bit to get you up to a good level where you're feeling the effects of it. You're feeling better, you're recovering better, your skin's looking better, you're burning fat quicker, and things of that nature.

SPEAKER_02 33:51

So I'll be clear. Just I I on the outside am not sure that Nicole needs more energy. The rest of us are struggling to keep up with her anyway.

SPEAKER_00 34:04

That's amazing.

SPEAKER_02 34:05

Yes, she wears many hats. Okay, so in addition to peptides, peptide therapies, things like this, hormones, we've talked about what else should we be doing to look and feel our best outside of that? What kind of skin treatments, what kind of nutrition? What should we be doing?

SPEAKER_00 34:22

I mean, I think everything starts in the kitchen. So your diet is like honestly, if I could say one thing is drink water. I don't know. Like I feel like so many people don't, but like you can agree that like when you don't drink water versus like you have a day that you drink two or three Stanley's, like your skin looks better, you feel better, your brain, you think clearer. Like so many people are walking around dehydrated and don't even realize it. And that's why they feel like crap. So it's me. It's me. I'm doing it. I'm guilty of it too. But one thing I did start doing, which I recommend to most of my wellness clients, is an electrolyte powder in the morning. Do you have a favorite? I can send you a link. There's one on Amazon that I like. You have to look at the sugar content because, like those liquid IVs and I think LMNT or some other brand, I don't know, they have a lot of sugar in them. So you have to find some that are not as high in the sugar content. And also the salt component of it is really important. Some of them literally have like table salt. You want it to be what's it called? Like sea salt or something where it's more mineral.

SPEAKER_02 35:29

Please do send us the link. That would be very helpful.

unknown 35:31

Okay.

SPEAKER_00 35:32

But I think that just kind of helps water water, nutrition, you know, protein is huge. Ideal amount of protein is one gram per pound of ideal body weight. So if your ideal body weight, if you're five five, it's around 120 pounds. So you should be getting around 120 grams of protein a day. Um, so that's a really, yeah, a lot of people, when I say that, are like shocked. But it's honestly, it doesn't sound realistic, but if you are getting around 20 to 30 grams of protein per meal, which most people are, if you're getting, you know, eggs, yogurt in the morning, you know, salad with chicken or something at lunch, and then dinner, get your lean protein, you're getting around like anywhere from 80 to 100 grams of protein right there. And then with snacking, just getting like Greek yogurt, cheese, nuts, like things where your protein bars, even protein shakes. It's not as hard as you would think to get it in.

SPEAKER_01 36:28

So bagels and pasta and candy bars aren't the right thing.

SPEAKER_00 36:32

I don't know. My kids said there's protein in bagels. I'm like, is there? I don't know. I guess they do have like six grams of protein or something. I'm going with them. It's better than nothing. But yeah, nutrition, I say everything starts with nutrition and then muscle, building muscle. That's like how you stay young. I truly believe it. You know, especially as women, we need muscle to support our bones because our bones start, you know, depleting as we get older. And then you need that resistance training too to keep your bones strong. So those are like the two big things like that you can change today. And then as far as like aesthetic treatments, sculpture, I am a big sculpture believer. If you haven't had sculpture before, I've been dying to understand what is it? Sculptra is a biostimulator. So something else, too, like these biostimulators are becoming more and more widely used because people want to go the more natural route as opposed to just putting a dermal filler, a hyaluronic acid filler in your face and putting a band-aid on it, more or less. Biostimulators go in and they're actually so sculptural is actually made up of dissolvable sutra material, like really, really tiny particles of it. We mix it with bacteriostatic water in some numbing solution as well, inject it, and then your body works to dissolve it. And in the process is building collagen elastin. So yeah. So do you inject it more like a filler or like where a filler would have historically gone? Exactly. Yeah, it's often like grouped in with fillers. Some people think it is a filler, but it's not. But yes, it's injected similar to a filler, depending on what you're coming in with, what your concerns are. We'll obviously focus in more on areas that you're seeing the signs of aging, but it's injected globally. So we start from like your temples, your midface, so your cheeks, and then this little space here called your piriform space. When we start to see like nasal labial folds showing more, that can just kind of help pop that out a little bit. And then your jawline, your chin. It's a really great way to just kind of like globally restore some of that loss of volume. And it also helps with your skin quality as well, which is really great. So sculptra is a good one, skincare, just you know, washing your face morning and night, vitamin C in the morning, vitamin C serum, and then a retinol at night, and then SPS, SPF every day. Whether you're going in the car to the grocery store, you should always be wearing it. There are so many great, you know, SPF foundations that we can use now that you know you put it on in the morning, and yes, you should be reapplying it if you're gonna be at the beach or on the boat, but they're it's so easy to do now, I feel like. So yeah.

SPEAKER_02 39:03

I mean, I those I have melasma, so I use chemical and minerals coverage every day and wear a hat the whole nine yards.

SPEAKER_01 39:12

And yeah, I think you missed your calling, my gland. I feel like you could be in the aesthetics business.

SPEAKER_02 39:18

I know, yeah. You seem to know a lot about stuff. I'm just very I it's my dad. My dad is a weirdo in a the best possible way. I love it, but he like he has a hyperbaric chamber in his house. Like he's gonna get along. Yeah, he's so much fun. So all the time I hear these things or I see things on Instagram, or I see, and I just send him a picture. I'm like, what is this? Is this real? Is this a bunch of hooey? And he will tell me. He he he prints up this whole thing of all these questions he wanted me to ask you about NAD. I'm I'm just gonna hold on those.

SPEAKER_00 39:51

Just tell him to set up a consultation with me. My consultations are complimentary and we can chat for an hour about all of his questions. He would love it, he would just absolutely love it.

SPEAKER_02 40:02

Oh, I love that. He sounds like a fun guy. I feel like we get along. He's the best, so he's gonna live forever, and hence hopefully I will too. Yeah, he's passing that on to you. I love it. Okay, one thing I have noticed more of that I would love your thoughts are in addition to feeling good, looking good. What about like brain health? What can we do to keep our brains? We're caring so much, we're working moms, we've got all these kids. So I think of our brains as like a sponge, and eventually you put too much in the sponge, liquids gotta fall out. What can we do to kind of just improve like that memory and context? What do we do?

SPEAKER_00 40:43

Nutrition. Nutrition is a huge part of our brain health, but also sleep is something that I feel like is often overlooked. I wear my aura ring. I don't know if you guys have any kind of trackable devices, but I've had this for like two years now, and that was really eye-opening for me just to see how bad my sleep was. You know, I I used to say, like, oh, I'm one of those people that can run on five hours of sleep and I'm fine. And then I started seeing these stats and like how bad my sleep was, how bad my recovery was. And I was like, oh my gosh, like maybe I'm not a five hour sleep, five-hour night sleep person. Like, so sleep is a really big part of our brain health and keeping, you know, everything working well, and not just your brain health, but you know, your metabolism, everything. If you're not sleeping well, you're not going your body's in a constant state of fight or flight, and your cortisol levels are going to be high, and it's just gonna be everything's gonna be harder. So yeah, and it's always sleeper. Yeah, sleep hygiene. So just finding a routine at night, winding down, no screen time, you know, 30 to 45 minutes before bed, meditation, you know, even if it's like like I have a Peloton app with guided meditations on there that I'll do sometimes, like finding ways to help your brain unwind at night, and then really doing what you can to get some good quality sleep. And that's where things like peptides can come in handy. We have peptides that help with sleep. Something that starts to decrease as we age is the amount of deep and REM sleep cycle that we get. So there's peptides.

SPEAKER_02 42:15

I do not sleep. A terrible sleeper, I've always been a terrible sleeper, and when I try to meditate, I like I get angry. Like I said, no, you will not relax.

SPEAKER_01 42:28

Yeah. What about uh magnesium? Is that something that we should all be taking at night before we go to bed?

SPEAKER_00 42:34

Absolutely. Yeah, magnesium is so important, helps a lot too with just like overall stress and anxiety. But yes, magnesium can help a lot with sleep and kind of helping you unwind and relax at bedtime. I have a really great one that I can recommend to you as well. Oh, yes, please definitely recommend that.

SPEAKER_02 42:50

How do you feel about creatine?

SPEAKER_00 42:52

Love it.

unknown 42:53

Okay.

SPEAKER_00 42:54

Take it every day. Everyone, all women should take it every day.

SPEAKER_01 42:56

I took it today too. I have the little gummies, they're very good.

SPEAKER_00 43:00

Yeah, there's there's a I mean, I feel like it's similar to hormones, how a lot of like there was that stigma that like creatine was for bodybuilders and women shouldn't take it because it's going to make you puffy. And no, it's one of the most studied supplements out there, and there's so many great studies about it, and especially studies in women and how beneficial it is for women and perimetopausal women. Um, it can even help with estrogen balance. So definitely recommend creatine. Five grams a day is what most women should be taking.

SPEAKER_02 43:30

Yeah, I take it. I put it in my coffee every morning because I feel like it dissolves in a warm liquid better than just water. I love it. I I I literally have a really hard time concentrating without it when I don't take it.

SPEAKER_00 43:43

I do too. I have an like an ADHD patient who she told me she takes, she doubles it. She takes 10 grams a day because she her ADD is so bad, but she takes it double the amount. She said it has been life changing for her.

SPEAKER_02 43:56

I feel like I have ADHD too. I I do feel it. I don't feel Like it was as popular when I was younger to get it diagnosed or to treat it. But my son has it and I know it's genetic. And I was actually telling somebody this story the other day, but I feel like when I was a kid, I always thought I was psychic, like I could predict the future. I knew what you were about to say. I knew what was about to happen. But I really think now as an adult, it was just ADHD the whole time. Yeah. Same.

SPEAKER_00 44:23

Same. Yep. I like look back at just school when I was in like middle school, high school. And I never did well in school, but I also never really tried. So it was just I didn't know how to focus. I had a hard time with focus, but now in hindsight, I'm like, wow, like if I knew then what I know now, I would have been so much better off. But I mean, everything happens for a reason, right? Yes, we're here. I made I made it somehow, but but yeah, so I think that creatine can definitely help with that for sure. And there's other peptides too.

SPEAKER_01 45:00

I think you've mentioned nutrition so many times on this. I think we need to share some recipes, some good nutritious recipes with the crowd. So feel free to send them over.

SPEAKER_00 45:11

Yeah, no, I think just like honestly, it's hard, you know, with kids, it's hard. You're running from one process to the next.

SPEAKER_02 45:18

And yes, we're just on the go. It's like I know how to make chicken at home, but what if we've got triple sports booked and not I can't go home and grill a chicken? Yeah. Or like we travel from work so much, you know. It's got to be something grab and go. I will say I am obsessed with Siggy's yogurt. If you guys have not seen it, I think it's like I don't know if it's a yogurt or a skier, but it has like 15 grams of protein in one yogurt, whereas the traditional even Greek yogurt is probably closer to eight or nine. Yeah, it's so good. It's really good too.

SPEAKER_00 45:52

Yeah, they are the vanilla bean one's my favorite.

SPEAKER_02 45:55

Me too.

SPEAKER_00 45:56

And the vanilla bean with cinnamon I love. Yes. The overnight oats, have you had those before? They're like usually in the like the produce section of Target. And then at Publix, they're by the yogurts, and they're called Mush, I think is the brand. Oh, okay.

SPEAKER_03 46:12

I've seen them.

SPEAKER_00 46:13

They have like double chocolate, is one of the flavors, blueberry. There's all different flavors, but those are so good. And we make like a little concoction where I put the oats on the bottom, yogurt on top, and berries, and my kids love it. Like it's like our own little homemade parfait, and it's easily like 30 grams of protein. Oh, so if you have athlete, like that is really good. Good way to start the day. Get some protein in there, especially these kids now with all the testing. I'm like, you got to get a good meal in the morning, keep your brain working well all day. Yep.

SPEAKER_02 46:45

Like it's always something. I know. Any other vitamins or supplements that we should be taking regularly?

SPEAKER_00 46:52

My god, if I showed you all the supplements I'm taking, you would be like, What in the world? I know we'll have to consider medicine cabinets here one day soon. It's pretty bad, but I you guys are gonna live forever and I'm not.

SPEAKER_01 47:05

So this is this is good.

SPEAKER_00 47:07

Funny you should mention that. I did, have you guys heard of the function health by Dr. Mark Hyman? It's like a membership. Yeah. Love Dr. Hyman. I did the lab panel where it's like 150 biomarkers to see, like, you know, how everything looked and where I was with my biological age, and my biological age is 25.

SPEAKER_03 47:29

Woo! No girl!

SPEAKER_00 47:30

I'm like, I'm 38 for reference. So I'm like, okay, well, all of these supplements and peptides that I'm spending hundreds of dollars a month on are actually working.

SPEAKER_02 47:40

They're working. All right, send us your whole list so we'll share it with everybody so we can follow forever.

SPEAKER_00 47:46

Yeah. No, I take a multivitamin, I take omega-3, I take magnesium at night, I take a vitamin D3 and K2, I take probiotics, oh, probiotics. Everyone should be on probiotics. Which one?

SPEAKER_02 48:01

Maybe on. I feel like I've tried a ton of them and none of them have ever worked.

SPEAKER_00 48:05

I can send you a couple recommendations, but that was one thing that I took away from the what the hormone certification course that I went to was everything starts in your gut. Hormonal imbalances start in your gut, everything starts in your gut. So if your gut is not well balanced and the bacterium's not well balanced, everything's gonna be off. And that even like with our children too, like I need to find a good probiotic for them. That's actually something that's been on my list to do. But they're saying there's so many, like our youth now is having they're having hormone imbalances because of our food and the quality of our food here. And their guts are so out of whack and out of balance that they're now suffering, you know, with hormone imbalances at very young ages and having fertility issues and things that were not an issue when we were younger. So yeah. What else? I think that's I think that's really it. Those are my like staples, yeah. Umega-3, everyone should be on omega-3, D3, K2. I think like 90% of our population is vitamin D deficient, even though we live in Florida, you think you're getting it, but you're not.

SPEAKER_03 49:17

Yeah.

SPEAKER_00 49:19

But yeah, those are the the main ones I'd say. Awesome.

SPEAKER_02 49:23

Awesome. All right. Well, we cannot thank you enough. I feel like we could easily do a whole other episode talking about this. I'm so excited. Where can people find you if they have more questions or if they're ready to book a consultation?

SPEAKER_00 49:37

So my Instagram handle is Lisa MarieWellness, all one word. And I have a link in my bio where you can book complimentary wellness consultations. I'm in West Chase in Florida, in Tampa. So if you want to see me in the office, you can, but I do virtual appointments as well. So I'm licensed in Florida, Colorado, working on a couple other states at this time, but hoping, hoping to expand there, but can see you virtually anywhere in Florida.

SPEAKER_01 50:08

So this is so yes, thank you so much, Lisa. We really appreciate it. And uh, I'm sure there will be a ton of questions, not only from us, but from our viewers. So we'll make sure to share everything with you and tag you along the way.

SPEAKER_02 50:21

Yeah, and we'll put all the links for whatever you send us in all of our socials as well at Double Booked Official Podcast and make sure that we start getting everybody the wellness that they deserve.

SPEAKER_00 50:32

Yes. And if we want to do like a follow up at some point, we can. You know, if there are a lot of questions that come, I'm happy to get back on here and do a follow up. Awesome. Thank you, Lisa. Thank you, Lisa. You're welcome.