Dr. Sprague is a clinical researcher with expertise in the design and conduct of large randomized controlled trials, observational studies, systematic reviews, and scoping reviews.  She obtained a Doctorate Degree in Medical Science from the University of Amsterdam and a Master of Science Degree in Health Research Methodology from McMaster University.  She became a Faculty Member with the Department of Surgery in 2014 and serves as an Associate Faculty Member in the Department of Health Research Methods, Evidence, and Impact in 2017.  In addition to her faculty appointments, Dr. Sprague serves as the Associate Director at the Centre for Evidence-Based Orthopaedics at McMaster University.