In 2007, my book, Lean & Hard – the body you’ve always wanted in 24 workouts, was published by John Wiley & Sons. L&H offered a comprehensive six week, four workouts per week diet, nutritional supplement schedule, resistive exercise, and sprint-interval program, all designed to increase lean muscle mass.
The L&H book was based on a research study of my concepts that followed a cross section of athletes and non-athletes over six weeks, when I was an Associate Professor in the LSU School of Public Health and Preventive Medicine.
One of the nutritional supplements tested in the applied research study and utilized in the book was creatine, an organic acid that is created internally from the action of the amino acids arginine, glycine, and methionine, which are constructed in the liver and regulated through kidney function.
Creatine predominantly resides in skeletal muscle—mostly as phosphocreatine—with roughly two percent degrading to creatinine, a metabolic by-product, which is why too much creatine may skew a creatinine clearance test assessing kidney function.
Creatine use by athletes has been widely studied for its side effect of weight gain, which was initially thought to be fluid gain, but after years of research, has now been determined to be lean muscle development—when used correctly.
I came to the conclusion, after seeing the results of the LSU applied study and my continued research on creatine, that someday creatine monohydrate would offer additional benefits to an ageing population—specifically to address sarcopenia—the age-related loss in muscle strength (dynapenia), muscle mass, muscle quality, and physical performance (frailty issues).
That day has now arrived.
New research, “Current Evidence and Possible Future Applications of Creatine Supplementation for Older Adults,” appearing in the March 2021 online, peer-reviewed journal Nutrients, comments that, “sarcopenia typically occurs in 8–13% of adults ≥60 years of age, and, is associated with other age-related health conditions, such as osteoporosis, osteosarcopenia (muscle related bone loss), sarcopenic obesity, physical frailty, and cachexia (muscle loss due to disease).”
Muscle mass decreases by 0.45% in men and by 0.37% in women. However, these decrements climb to 0.9% for men and to 0.7% for women starting in their seventh decade.
The age-related decrease in muscle strength—a strong predictor of poor health outcomes, such as mobility disability, falls, fractures, and mortality in older adults—occurs more rapidly (2–5 times fold faster) than the reduction in lean (muscle) mass.
The Canadian and Australian study authors performed a narrative review evaluating the current research involving creatine (CR), with and without resistive training (RT), on properties of muscle and bone in older adults, “in order to provide a rationale and justification for future research involving CR in older adults with osteosarcopenia, sarcopenic obesity, physical frailty, or cachexia.”
Here’s what was determined.
As it pertains to addressing sarcopenia, “CR (≥3 grams/day) and RT (≥7 weeks; primarily whole-body routines) can improve some measures of muscle accretion, strength, and physical performance in older adults. Independent of RT, a CR loading phase and/or high relative daily dosage of creatine (≥0.3 g/kg/day) may be required to produce some muscle benefits in older adults.”
Relative to creatine usage with osteoporosis—the age-related loss of bone mineral density – “collectively, the vast majority of studies show no greater effect from CR, with and without RT, on properties of bone in older adults.”
To read the rest, go to maxwellnutrition.com