
The Human Guinea Pig Project
The Human Guinea Pig Project is a podcast series where individuals discuss alternative methods of managing complex medical conditions and disease where the standard of care offers little promise.
The Human Guinea Pig Project
Repurposing loperamide to target glioma, metabolic reprogramming, liquid biopsies.
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Andrew Scarborough
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Season 1
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Episode 11
In this episode, recorded just before the New Year, I discuss recent news in brain cancer research.
This includes:
How the drug loperamide (brand name Imodium), induces cell death in glioblastoma cell lines and if this could have promise for real, human applications.
Metabolic reprogramming via inhibition of a key cancer metabolite- D-2-Hydroxyglutarate (D-2-HG).
Developments of liquid biopsies for glioma.