Hold onto your lab coats as we delve into the astonishing medic skills of the Matabelle ants and their natural antibiotics, a discovery with implications that could ripple through human healthcare. We'll chuckle together at AI's attempts at artistic genius and its more practical uses in the operating room, and then ponder the ethical maze surrounding a pioneering pig liver medical procedure.
Allergies got you sniffling? We've got the scoop on how nanoparticles might be the game-changer we've been sneezing for, thanks to groundbreaking research from Northwestern University. While we're at it, let's not forget about the superhero in the room: breast milk. Discover how this liquid gold is rewriting the rulebook on infant immunity. Prepare to be both enlightened and entertained as we merge cutting-edge science with hearty humor throughout our latest episode.
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Ever felt curious about the behind-the-scenes of animal research and the fascinating technologies being leveraged? Well, strap in as we embark on an enlightening journey, unveiling the intriguing world of animal research and its advancements through the lens of CRISPR-Cas9. We're discussing how a team at the University of Basel is revolutionizing gene-editing to minimize the use of mice in muscle disease studies.
Our discussion doesn't stop at gene editing! We dive into the nitty-gritty of how Harvard Medical School researchers are utilizing cells to control excessive muscle inflammation. We'll unpack how this could potentially assist elderly individuals in maintaining endurance and muscle tone for longer. We spice it up a notch with a captivating study showcasing how rats are trained to visualize routes and tasks in a virtual reality environment. We're not just discussing the science, we're exploring its fascinating implications on animal behavior and focus.
We conclude on a thrilling note, calling out to our listeners for exciting future guest suggestions and more engaging content. Keep your ears open for news about giveaways and bonus content.
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
Ever wondered if taurine could be the secret to longevity and health span? We got curious and decided to investigate. With insights from animal studies, we explore if taurine could help combat obesity, inflammation, blood pressure, and type two diabetes.
Brace yourselves as we step into the future of medical technology, celebrating the astonishing strides made in organ transplants. From its history to the success of the two most recent transplants, we unpack it all. And just when you thought it couldn't get any more fascinating, we talk about the potential use of viruses found in animal poop in treating diabetic foot ulcers. Buckle up for this thrilling journey, and don't forget to connect with us on social media for more exciting content. Thanks for listening, and we promise to be back with more episodes soon!
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Lab Rat Chat - Episode 34 with Dr. Ben Wylie
Get ready to embark on a fascinating scientific journey with our esteemed guest, Dr. Ben Wylie. We know you're curious about his career journey, his cutting-edge work in sarcoma research, and his innovative approach towards cancer treatment. So, we promise you an enlightening conversation that is sure to feed your curiosity and inspire your scientific spirit.
In the first part of our conversation, Dr. Wylie takes us through his journey, from his childhood fascination with the natural world to his current role in cancer research at the Telethon Kids Institute. He opens up about his career transitions, his love for academic research, and the critical work his team is doing in pediatric sarcoma to utilize a biodegradable material to deliver immunotherapy during surgery. This approach, which targets invisible micrometastatic disease left behind during surgery, could potentially transform the landscape of post-surgical cancer treatment.
The conversation takes an exciting turn towards veterinary research and the canine clinical trials to test the efficacy of their immunotherapy gel in dogs diagnosed with sarcoma. We discuss what hopes to be very promising results from this trial and how it can hopefully be translated into the human world. Stay tuned, and prepare for a thought-provoking ride into the world of scientific innovation.
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
Links to all these stories can be found below
In this episode, we also tackle topics from tornadoes to termites and share our personal experiences with these natural disasters and the chaos that sometimes ensues. Don't miss out on this fascinating and fun-filled conversation!
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Lab Rat Chat - Episode 33 with Dr. Alejando Torrado-Pacheco
What if psychedelics could hold the key to improving mental health? Join us for an inspiring conversation with Dr. Alejandro Torrado-Pacheco, a postdoc from Oregon Health Sciences University, as we journey through the world of psychedelics and their potential therapeutic applications. Alejandro shares his unique background, from growing up in Europe and studying physics, to ultimately transitioning into neuroscience and then behavioral neuroscience. We also learn about his current research in Dr. Bita Moghaddam's lab, which focuses on the fascinating potential of psychedelics to enhance mental well-being.
Dr. Torrado-Pacheco provides valuable insights into the history of psychedelics, the importance of set and setting for these experiences, and how animal research can help us better understand their biological mechanisms. Don't miss this opportunity to learn about the potential therapeutic benefits of these fascinating compounds and how they could reshape our understanding of mental health treatment in the near future.
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
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Lab Rat Chat - Episode 32 with Dr. Jodi Salinsky
In this episode of Lab Rat Chat, Jeff and Danielle chat with Jodi Salinksy, DVM, Animal Welfare Officer for the University of Auckland, New Zealand. We're thrilled to finally talk with someone from New Zealand to be able to compare and contrast some of the similarities and differences regarding animal research in that part of the world.
Topics discussed in this episode:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
Links to all these stories can be found below
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Resources & Links:
Monogamous Prairie Voles:
https://www.npr.org/sections/health-shots/2023/01/27/1152009605/prairie-voles-oxytocin-love-hormone-bonding-study
FDA Modernization Act:
https://www.science.org/content/article/fda-no-longer-needs-require-animal-tests-human-drug-trials
Freezing Hibernating Frogs:
https://www.manisteenews.com/news/article/Wildlife-Wednesday-This-Michigan-frog-could-help-17722836.php
Heart Scar Tissue Repair Story:
https://newatlas.com/medical/tropoelastin-injection-heart-scar-tissue/
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Lab Rat Chat - Episode 31 with Erin Vogelsong
In this episode of Lab Rat Chat, Jeff and Danielle chat with Erin Vogelsong, MS, Program Director of Drexel University's Master of Laboratory Animal Science program.
Special Live Webinar Announcement - February 1st @ 12pm EST:
In celebration of International Laboratory Animal Technician Week, Drexel University is hosting a webinar Bringing the Magic Through Podcasting: A Behind the Scenes Look Into the Lab Rat Chat Podcast. The webinar will feature Danielle Dady and Jeff Marshall, the hosts of Lab Rat Chat, and will give participants an inside look into the magic that goes into creating each and every episode. Tune in to learn more about the hosts, why Lab Rat Chat was created, the insider scoop on Jeff and Danielle’s favorite episodes, some of the mistakes made and lessons learned, and what to expect from Lab Rat Chat in the future. Visit Online.Drexel.Edu/LabRatChat to register.
Topics discussed in this episode:
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Lab Rat Chat - Episode 30 with Dr. Agnès Lacreuse
In this episode of Lab Rat Chat, Jeff and Danielle chat with Dr. Agnès Lacreuse, PhD, who is a researcher at the University of Massachusetts in the Department of Psychological and Brain Sciences Department.
She utilizes nonhuman primates in her research in order to better understand neurocognitive aging and pathological aging processes, such as those involved in Alzheimer's disease. Two-thirds of Alzheimer's disease cases in humans are women. 2/3 of AD cases in humans are women. For this reason, we also aim to understand how changes in sex hormones, especially estrogens, affect brain and cognitive aging in females.
Topics discussed in this episode:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
Links to all these stories can be found below
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Resources & Links:
Benefits of Fat in the Body Story:
https://www.the-scientist.com/news-opinion/how-fat-cells-help-kick-parasites-out-of-mice-study-70627
Needleless Jet Injection Story:
https://www.biospace.com/article/on-the-horizon-needle-free-vaccination-could-offer-better-protection-and-access-/
Reviving Pig Organs After Death Story:
https://www.science.org/content/article/pig-organs-revived-1-hour-after-animals-death
Elephants and Cancer Story: https://m.dailykos.com/stories/2022/10/23/2130664/-Top-Comments-Elephants-Rarely-Get-Cancer-Why
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All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/
News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
Links to all these stories can be found below
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Lab Rat Chat - Episode 29 with Dr. Kyle Flippo
In this episode of Lab Rat Chat, Jeff chats with Dr. Kyle Flippo, PhD, who is a postdoc in the University of Iowa Neuroscience and Pharmacology Department. He studies the role of endocrine signaling in the CNS in regulating metabolism, amongst other things. One of his current research projects has explored the role of a hormone (FGF21) in suppressing alcohol consumption in monkeys. Not only is this promising for providing a treatment for alcohol use disorders, they've also found this hormone plays a major role in reducing sugar intake as well. This research is really groundbreaking stuff and thankfully we have scientists out there like Dr. Flippo who works compassionately with laboratory animals to make these sorts of discoveries.
Topics discussed in this episode:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
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Lab Rat Chat - Episode 28 with Dr. Amanda Vanderplow
In this episode of Lab Rat Chat, Danielle and Jeff chat with Dr. Amanda Vanderplow, a PhD research scientist in the Cahill Lab of Neuroscience Research at the University of Wisconsin-Madison. She studies dendritic spine plasticity and how synaptic alterations contribute to neuropsychiatric disorders. In other words, she much smarter than the rest of us. One of her current research projects discovers a potential link between sleep apnea and autism-like behaviors. This could be one of those breakthrough discoveries that allows us to prevent and/or reduce the rising prevalence of autism-like behaviors in society today, and we have Dr. Vanderplow, her team, and her rats, to thank for discovering this link.
Topics discussed in this episode:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
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Lab Rat Chat - Episode 27 with Dr. Christine Lattin
In this episode of Lab Rat Chat, Danielle and Jeff chat with Dr. Christine Lattin, an assistant professor at Louisiana State University. She conducts incredible research using birds as a model to help our understanding of stress and how different neurotransmitters and hormones help wild animals successfully cope with challenges, from predators to disease. Dr. Lattin's research will advance our understanding of how these hormone and neurotransmitter pathways work in humans as the pathways are very similar amongst all vertebrae species. We also discuss an extensive and uncalled-for attack campaign by PETA on Dr. Lattin's research and personal life and how she's been able to continue to thrive and overcome these challenges.
Topics discussed in this episode:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
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News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).
In this News Bite edition, Jeff and Danielle discuss:
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Lab Rat Chat - Episode 26 with Dr. Roy Taylor
In this episode of Lab Rat Chat, Danielle and Jeff chat with Dr. Roy Taylor, a physician and author, who is currently the Director of Newcastle Magnetic Resonance Centre at Newcastle University. He has been conducting research on type 2 diabetes since 1978 and in 2011, Taylor showed that the disease was a simple, reversible condition of excess fat within the liver and pancreas. Taylor developed the system now used throughout the United Kingdom for screening for diabetic eye disease, which has resulted in a major reduction in blindness due to diabetes across the UK. He is the author of Life Without Diabetes, a popular guide to understanding and reversing type 2 diabetes and achieving lasting remission (link below).
Topics discussed in this episode:
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