Gavin and Jessamy welcome back Oksana Pyzik of UCL to talk about the significant impacts of Trump's actions on health infrastructure in Ukraine and broader Europe.

Oksana provides a comprehensive update on the current health situation in Ukraine, the challenges faced by healthcare systems amidst ongoing conflict, and the repercussions of halted aid on crucial programs like HIV and TB. 

We also explore the response of international institutions responsible for coordinated efforts to address pressing health issues and discuss what a tariff schedule might mean for the pharmaceutical industry.

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Gavin, Richard, and Jessamy reunite for another bonus episode, covering the first three months or so of health in the US under Trump. What do the appointments tell us about the administration's agenda? How can institutions stand up to cuts and intimidation? 

We also look at gender justice in global health as laid out by the excellent new Commission in The Lancet, and highlight that the world's impressive gains on maternal and newborn mortality are slowing - what more needs to be done?

You can read "Achieving gender justice for global health equity: the Lancet Commission on gender and global health" here:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00488-X/fulltext?dgcid=buzzsprout_tlv_podcast_lancetgenderhealth25_lancet

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Following the discovery of H5N1 influenza of avian origin in a sheep in the UK this week, Gavin is joined by Dr. Abraar Karan of Stanford University to discuss the current state of bird flu in the US, its impact on public health, and the potential for human-to-human transmission. Dr. Karan analyses the ongoing outbreaks and infections in the US, the challenges in detecting and controlling the virus, and the lessons learned from COVID-19.

We chat about the complexities of viral evolution, the importance of robust testing and surveillance, the critical need for coordinated efforts to prevent a potential epidemic, and how bird flu might end.

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Content warning: discussions of sexual assault, violence, and rape

How does society handle sexual assault? What are the health implications for victims and for populations? Did the Pelicot case change attitudes and what can we do to address stigma? 

Gavin is joined by Professor Betsy Stanko OBE and Professor Katrin Hohl OBE, who together worked on the London Metropolitan Police's Operation Soteria to change how the police deal with sexual assault cases. 

In this episode, we explore the global burden of sexual violence, its profound impact on women's health, the systemic challenges in addressing the hidden dimensions of sexual violence, the difficulties in measuring its prevalence, and the critical need for a trauma-informed and holistic approach in both healthcare and criminal justice systems.

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Gavin is joined by Heather Wardle, Professor of Gambling Research and Policy at the University of Glasgow, and the lead commissioner on The Lancet Public Health’s Commission on Gambling, to discuss the rapid expansion of the global gambling industry and its profound public health implications. We chat online gambling, technological advancements, and increasing accessibility, and how they are transforming the gambling landscape, leading to widespread health harms.

You can read the Commission here:

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(24)00167-1/fulltext?dgcid=buzzsprout_tlv_podcast_lanpubgambling24

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Donald Trump has taken office in the US and immediately turned his attention to dismantling the US position as a world leader in global health. How will actions taken so far affect the health of people around the world? Gavin is joined by co-host Miriam Sabin, North American Executive Editor at The Lancet, and they speak to Dr. Gavin Yamey, lead author of The Lancet's recent Commission on Investing in Health, and Director of the Center for Policy Impact in Global Health at the Duke Global Health Institute.

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Richard, Gavin, and Jessamy return to the studio for another freeform discussion kicking off with the responsibilities of science and scientific publishing in a time where fact checking and moderation are going out of fashion. We also cover climate change in the US with the recent wildfires, and the importance of retaining institutional memory following traumatic experiences after Richard was particularly struck by a recent trip to Argentina.

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Where does power lie in global health? What are the historical and systemic barriers that perpetuate inequities, and what is the impact of political shifts towards nationalism? 

Catherine Kyobutungi and Madhukar Pai join Gavin to talk about their recent Comment published in The Lancet, "Shifting power in global health will require leadership by the Global South and allyship by the Global North". Join us to learn about the challenges and opportunities for Global South leadership and the importance of redefining knowledge, success, and problem identification in global health.

You can read Catherine and Madhu's Comment piece here:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02323-7/fulltext?dgcid=buzzsprout_tlv_podcast_generic_lancet

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The last Lancet Voice of the year delves into the latest findings from the Institute for Health Metrics and Evaluation (IHME) from our recently released US Special Issue. Ali Mokdad and Emmanuela Gakidou join Miriam Sabin and Gavin Cleaver to explore the comprehensive analysis of the Global Burden of Disease, the alarming trends in obesity and life expectancy, and the critical need for policy changes to improve public health in the United States.

Read the US special issue here:
https://www.thelancet.com/journals/lancet/issue/vol404no10469/PIIS0140-6736(24)X0050-1?dgcid=buzzsprout_tlv_podcast_generic_lancet

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In September 2023, Wales passed legislation making the maximum speed limit 20mph in built-up areas. How are speed limits linked to public health? How can researchers engage with governments to enact public health research? And how do you deal with the situation when there is a huge online backlash to your work? Dr. Sarah Jones from Public Health Wales joins Gavin to discuss how her research was implemented, how it's gone so far, and what's next.

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What is the impact of systemic racism on public health in New York City? How can we leverage government to meet ambitious goals for improving life expectancy?

Prof. Michelle Morse, the interim Health Commissioner of the Department of Health of New York City, joins Miriam Sabin and Matt Gilbert of The Lancet to discuss bridging public health and clinical care to reduce health inequities.

Together, they explore the challenges and solutions in addressing health across a diverse city, tackling maternal mortality, and the importance of community engagement in public health.

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Gavin, Richard, and Jessamy get into the studio for another bonus episode looking at the launch of the Global Health 2050 report at the World Health Summit in Berlin, a report which shows a path to cutting premature mortality by 50% by 2050. Also up for discussion are the limits of human longevity and what well-designed cities mean for health.

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The US is the richest country in the world, but has some of the most entrenched poverty and associated poor health outcomes. Miriam Sabin (North American Senior Executive Editor at The Lancet) joins Jessamy to chat with Luke Shaefer (Professor of Public Policy at the University of Michigan and Director of Poverty Solutions) and Mona Hanna (Professor of Public Health at Michigan State University and paediatrician at Hurley Medical Centre) about why this is, their innovative Rx Kids cash grant program for families in Michigan, and what the upcoming US election means.

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Gavin is joined by Paul Moran (Professor of Psychiatry, University of Bristol and Honorary Consultant Psychiatrist, Bristol Royal Infirmary, UK) and Helen Christensen (Scientia Professor of Mental Health at the University of New South Wales, Sydney, Australia) to discuss The Lancet's new commission on self-harm, exploring its prevalence, cultural factors, and the crucial need for better data and compassionate care. We also talk about stigma and improving mental health services globally.

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https://www.thelancet.com/commissions/self-harm?dgcid=buzzsprout_tlv_podcast_lancetselfharm24_lancet

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Jessamy, Gavin, and Richard come together for another bonus episode of The Lancet Voice. A freeform chat covers xenotransplantation, the use of AI in scientific research, the Darzi report into the UK's National Health Service, and falling population levels over the next few decades.

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Ramanan Laxminarayan is the founder and president of the One Health Trust, Director of the WHO Collaborating Center on Antimicrobial Resistance in New Delhi, India, and an Affiliate Professor at the University of Washington, Seattle, WA. He is the lead author of The Lancet’s May 2024 series on Sustainable Access to Antibiotics. He joins Gavin and Jessamy to discuss how big of a problem AMR currently is and will be, what is being done, and what needs to be done.

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https://www.thelancet.com/series/antibiotic-resistance?dgcid=buzzsprout_tlv_podcast_generic_lancet

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In something of a bonus episode, Gavin, Richard, and Jessamy sit down for an informal chat about what's going on in the news, in health, and in the world of The Lancet, covering healthcare emissions, solar power, and the challenge of global co-operation on vaccines.

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The mpox case surge in Africa has been declared a Public Health Emergency of International Concern (PHEIC) by the WHO. A new clade of the virus has emerged since the 2022 outbreak which has led to a rapid increase in cases. Professor Salim Abdool Karim, who is the the chair of the Africa CDC’s Emergency Consultative Group and the director of CAPRISA, the Center for the AIDS Programme of Research in South Africa, joins Gavin Cleaver and Maneet Virdi to lay out in clear terms what's happening in Africa, what the PHEIC means, and what the future could look like.

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The first module of the UK's COVID-19 enquiry was published in July 2024. The enquiry found that the UK prepared for the wrong sort of pandemic, suffered from groupthink, and ultimately failed its citizens, more than 200,000 of whom died as a result of the pandemic.
 
Editor-in-chief of The Lancet, Richard Horton, joins Gavin and Jessamy to discuss his experiences giving evidence to the enquiry. We reflect on the findings, dissect their meaning for pandemic preparedness, and talk about what the UK government needs to do next.

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14 modifiable risk factors account for 45% of dementia cases worldwide. Gavin and Jessamy are joined by Prof. Gill Livingston (UCL) and Prof. Geir Selbaek (University of Oslo) to discuss the 2024 updates to The Lancet Commission on dementia prevention.

You can read the Commission here:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01296-0?dgcid=buzzsprout_tlv_podcast_lancetdementia24_lancet

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Gavin and Jessamy are joined by Mandeep Dhaliwal, Director of UNDP’s HIV, Health and Development Group, to discuss the access to health and freedom of the most vulnerable people around the world. Are we maintaining progress on rights, or are we in danger of backsliding?

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Gavin and Jessamy are joined by Oksana Pyzik (UCL, Fight The Fakes Alliance) to discuss how Ozempic/Wegovy/semaglutide works, what becoming mainstream means for our understanding of obesity and public health, and how demand is fuelling an unregulated black market in the drugs.

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Anita Zaidi, President of The Gender Equality Division at the Gates Foundation, joins Gavin to discuss women in global health from visibility in data all the way through to women in leadership positions in global health. Also on the agenda is the impact of vaccines, innovations in gender equity, and challenges and successes in addressing maternal mortality.

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Gavin and Jessamy are joined by Rupa Sarkar, editor-in-chief of The Lancet Digital Health, to discuss the uses of Large Language Models (LLMs) in healthcare, the safety and patient concerns, progress that’s been made, and the what the future of AI in health might hold.

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What are the hidden costs of breast cancer? What advances in breast cancer treatment have been made, and how can we tackle the problematic inequities that remain? What needs to be done for patients with metastatic breast cancer? Gavin and Jessamy are joined by Felicia Knaul, Reshma Jagsi, and Fatima Cardoso to discuss the recent Lancet Breast Cancer Commission.

You can read the Commission for free by registering:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00747-5/fulltext?dgcid=buzzsprout_tlv_podcast_generic_lancet

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