#02 Feb ’20 Round Up: Nodules + NOACs + Prednisolone + more

Did you spend that extra leap year day in February keeping up with the medical literature? No? No problem, we’ve got you covered with a fresh look at the month's most relevant and interesting Gen Med articles.
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 In this month’s episode:

 …NELSON sails the high seas of lung cancer screening…

de Koning, Harry J et al. “Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.” The New England journal of medicine  https://pubmed.ncbi.nlm.nih.gov/31995683/

…the rise and rise of the NOAC…

 Inohara, Taku et al. “Decline in renal function and oral anticoagulation dose reduction among patients with atrial fibrillation.” https://pubmed.ncbi.nlm.nih.gov/31911503/

 Kuno, Toshiki et al. “Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Hemodialysis.” Journal of the American College of Cardiology https://pubmed.ncbi.nlm.nih.gov/31976865/

 
…why we should all brush up on our drug side effect monitoring…

 Savage, Rachel D et al. “Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With Hypertension.” JAMA internal medicine
https://pubmed.ncbi.nlm.nih.gov/32091538/ 

…Surely there’s more to it than just steroids?...

 Dobler, Claudia C et al. “Pharmacologic Therapies in Patients With Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review With Meta-analysis.” Annals of internal medicine. https://pubmed.ncbi.nlm.nih.gov/32092762/

 …when the question is steroids, might metformin be the answer?...

Pernicova, Ida et al. “Metformin to reduce metabolic complications and inflammation in patients on systemic glucocorticoid therapy” The lancet. Diabetes & endocrinology
https://pubmed.ncbi.nlm.nih.gov/32109422/

…to scope or not to scope for dyspepsia…
Sonnenberg, Amnon et al. “Low Prevalence of Helicobacter pylori-Positive Peptic Ulcers in Private Outpatient Endoscopy Centers in the United States.” The American journal of gastroenterology 

https://pubmed.ncbi.nlm.nih.gov/31972622/ 

***Irrelevantly relatively relevant articles*** 

Urinary Auto-brewery Syndrome: A Case Report https://pubmed.ncbi.nlm.nih.gov/32092761/

Sex rations & societal stress
https://pubmed.ncbi.nlm.nih.