#04 March '20 Round Up: Bicycles, stopping Ace-i, HIV injectables, IHD management, CFS/ME, ITU tips and... Baths

Are you trying to keep up with the general medicine literature but you are saturated with Covid Coughs, Swabs, Oxygenation, Isolation, Ventilation, and the Mortality of the Nation? Your ears are in the right place as we bring you last months most relevant
(and sometimes less relevant) general medicine articles.
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In this month's episode...

...why we shouldn't leave all the cycling to work to the anaesthetists...
Association of injury-related hospital admissions with commuting by bicycle in the UK: a prospective population-based study. BMJ.
https://doi.org/10.1136/bmj.m336

...ACEI/ARBs shine through some difficult COVID related PR...
Qiao, Yao et al. “Association Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration Rate.” JAMA internal medicine, e200193. 9 Mar. 2020, doi:10.1001/jamainternmed.2020.0193

...a new treatment regimen injects some life into HIV care...
Orkin, Chloe et al. “Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection.” The New England journal of medicine vol. 382,12 (2020): 1124-1135. doi:10.1056/NEJMoa1909512

....the ISCHAEMIA trial, morbidly expensive but no extra mortality...
Maron, David J et al. “Initial Invasive or Conservative Strategy for Stable Coronary Disease.” The New England journal of medicine vol. 382,15 (2020): 1395-1407. doi:10.1056/NEJMoa1915922

...brush up on treatment options for CFS/ME...
Kim, Do-Young et al. “Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME).” Journal of translational medicine vol. 18,1 7. 6 Jan. 2020, doi:10.1186/s12967-019-02196-9

...a few pearls to help with your ICU redeployment...
Lee, Robert Y et al. “Association of Physician Orders for Life-Sustaining Treatment With ICU Admission Among Patients Hospitalized Near the End of Life.” JAMA, vol. 323,10 950–960. 16 Feb. 2020, doi:10.1001/jama.2019.22523

Lamontagne, François et al. “Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial.” JAMA, vol. 323,10 938–949. 12 Feb. 2020, doi:10.1001/jama.2020.0930

...and finally, the great medical conundrum of our time...
Ukai, Tomohiko et al. “Habitual tub bathing and risks of incident coronary heart disease and stroke.” Heart (British Cardiac Society), heartjnl-2019-315752. 24 Mar. 2020, doi:10.1136/heartjnl-2019-315752
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