#07 JournalChat// COVID Hyperinflammation + HLH + ARDS : "Time is Lung"

The inspirational Dr. Sangita Agarwal (Rheumatologist) & Dr. Boris Lams (Respiratory), inflammatory lung specialists, take us through our emerging understanding of the complications of COVID-19: 

• Hyperinflammation
• ARDS
• Haemophagocytic lymphohistiocytosis (HLH)

Introduction
Background to the lung inflammation service (03:02)
The secret to the dynamic duo and navigating disagreement (05:15)

HLH: Haemophagocytic lymphohistiocytosis
HLH: what is it and why is it relevant in COVID-19 "The power of the immune system" (06:40)
Common triggers of HLH (08:40)
Screening for HLH and The H score (09:08)
Investigations for HLH and the return of ferritin (13:43)

ARDS
The basics of ARDS. Subtypes: "normal & atypical" (16:45)
HLH and ARDS (19:47)
COVID driving ARDS and the possible subtypes of "COVID ARDS" (20:40)

Hyperinflammatory COVID-19 & Therapies
Steroids and severe COVID-19 (28:05)
Potential therapies targeting the abnormal host response (32:01)
Lung fibrosis (38:54)

Conclusions
Take-home points (44:20)
TIME IS LUNG! (46:12)

Buzzwords
#Trialtastic
#Inflammologist
#TimeIsLung
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