#08 April '20 Round Up: Bundles + CPAPathon + Diet advice + MRSA....+ Squirrels

Are you trying to keep up with the general medicine literature but after completing Love is Blind and Tiger King, you’ve spent your evenings cringing through episodes of Normal People with your family?
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In this month's episode...
(05:11)...Sepsis bundles, not greater than the sum of their parts?...
Baghdadi, Jonathan D et al. “Association of a Care Bundle for Early Sepsis Management With Mortality Among Patients With Hospital-Onset or Community-Onset Sepsis.” JAMA

(10:39)...Aspirin might prevent HCC (and preserve flowers?)
Simon, Tracey G et al. “Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality.” NEJM

(17:30)...CPAPathon: ACS/OSA/CO (there's a good anagram in there somewhere)...
Sánchez-de-la-Torre, Manuel et al. “Effect of OSA and its treatment with continuous positive airway pressure on the prevalence of cardiovascular events in patients with acute coronary syndrome (ISAACC study): a randomised controlled trial.” Lancet
Wimms, Kelly et al. "CPAP versus standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): a multicentre, randomised controlled trial" Lancet
Turgut & Yavuz. "Comparison of non-invasive CPAP with mask use in carbon monoxide poisoning" AJEM

(27:52)...Diets and cardiovascular disease...
Ge, Long et al. “Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials.” BMJ 

(37:17)...Does MRSA bacteremia need anything more than vancomycin ...
Tong, Steven Y C et al. “Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial.” JAMA

(40:43)...is your stethoscope spreading the next pandemic?...
Sukaina Ali Alali et. al "Community Hospital Stethoscope Cleaning Practices and Contamination Rates" AJIC

(44:24)...JOURNALBITES...
Benzo-resistant status epilepticus
Penicillin allergy decision rule
New anaphylaxis guidelines
SGLT2 inhibitors and heart failure

(50:07)...Medieval strains of m. leprae in the red squirrel...