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In this episode of The Oncology Journal Club, the team weigh promising trial signals against the level of evidence needed to change clinical practice. From perioperative cholangiocarcinoma to molecular matching and chrono-oncology, the focus stays on a key question: what meaningfully improves outcomes for patients?

What’s covered

•  NeoGOLP trial in high-risk resectable iCCA: improved event-free survival; overall survival still immature 
•  MoST programme: molecular matching and survival associations when therapies align with biomarkers 
•  Genomic therapy matching in clinical decision-making 
•  Chrono-oncology: does treatment timing influence outcomes? 
•  CHOPIN phase II uveal melanoma trial: combination therapy signals and feasibility 
•  ASCO living guideline updates across lung, gastro-oesophageal and thyroid cancers 

The Oncology Journal Club Podcast hosted by Professor Craig Underhill, Dr Kate Clarke and Professor Chris Jackson, and proudly produced by The Oncology Network

Visit oncologynetwork.com.au for Show Notes, to send us Voice Notes and more information.