Leaders on a Mission

How AI Is Reshaping Sustainable Chemistry

Simon Leich

Computation is killing the wet lab—and reshaping enzyme innovation in the process. Maria Fátima Lucas, CEO of ZYMVOL, shares how AI and physics-based simulation shrink enzyme discovery from 100 million sequence variants to fewer than 300 lab-tested hits—cutting timelines, risk, and cost by orders of magnitude.

In this episode, Maria unpacks how ZYMVOL is making biocatalysis not just greener, but cheaper and faster—bringing clean chemistry to sectors previously priced out. From Europe’s regulatory drivers to a bold product pivot into bio-based melanin, this is a rare look inside a deeptech company scaling with precision, not hype.

Tune in for a fresh look at building ventures that last, not just raise.


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Hey Climate Tech enthusiasts! 


Searching for new podcasts on sustainability? 

Check out the Leaders on a Mission podcast, where I interview climate tech leaders who are shaking up the industry and bringing us the next big thing in sustainable solutions. 

Join me for a deep dive into the future of green innovation exploring the highs, lows, and everything in between of pioneering new technologies.

Get an exclusive insight into how these leaders started up their journey, and how their cutting edge products will make a real impact.

Tune in on…


YouTube: https://www.youtube.com/@leadersonamissionNet0

Spotify: https://open.spotify.com/show/7o41ubdkzChAzD9C53xH82

Apple Podcasts: https://podcasts.apple.com/us/podcast/leaders-on-a-mission/id1532211726


…to listen to the latest episodes!


Timestamps:

00:00 – Clean chemistry = mission

02:41 – From pharma to enzymes

05:07 – Bootstrapping for 6 years

07:03 – AI + physics workflow

10:55 – Why cost always wins

11:15 – Regulatory bans as tailwind

14:52 – End-to-end solution model

19:31 – First hits in 3 months

23:47 – Enzyme marketplace vision

28:42 – Bio-melanin case study

35:24 – Fundraising and future


Useful links:

ZYMVOL  website: https://zymvol.com/

ZYMVOL LinkedIn: https://www.linkedin.com/company/zymvol/

Maria Fatima Lucas LinkedIn: https://www.linkedin.com/in/fatimalucas/

Leaders on a Mission website: https://cs-partners.net/podcasts/

Simon Leich’s LinkedIn: https://www.linkedin.com/in/executive-talent-headhunter-agtech-foodtech-agrifoodtech-agritech/