Progress, Potential, and Possibilities Podcast / Show
Interviews and Discussions With Fascinating People Who are Creating A Better Tomorrow For All Of Us - Host - Ira S. Pastor
Episodes
841 episodes
How argenx Is Reinventing Autoimmune Treatment | Dr. Luc Truyen, M.D., Ph.D., Chief Medical Officer, argenx
Most autoimmune drugs suppress the immune system broadly - but what if you could selectively remove the antibodies actually causing disease? That’s exactly what VYVGART is doing, and it may fundamentally change how we treat conditions like myas...
Reversing Humanity’s #1 Killer - Arterial Plaque | Dr. Matthew O’Connor, Ph.D. - CEO and Co-Founder - Cyclarity Therapeutics
In the time it will take you watch this episode, over 2,000 people around the world will die from diseases driven by arterial plaque. But what if we could actually remove the toxic cholesterol already trapped inside arteries?Today we’re...
Fixing the $100B Fluid Overload Crisis in Heart & Kidney Disease | Ryan Marthaler - Vice President of Product Marketing and Business Development, Nuwellis
One of the biggest drivers of hospital admissions isn’t what most people think - it’s fluid. Not infection, not surgery…fluid overload. And when the body stops responding to diuretics, medicine runs into a wall.Today we’re exploring one...
Pharma’s Biggest Blind Spot: Why 99.9% of Chemical Space Was Never Explored | Dr. Olga Nissan, Ph.D. - Vice President of Business Development, Evogene
Pharma has only explored a tiny fraction - less than one-tenth of one percent - of all possible drug-like molecules. So the question is: what happens when AI suddenly opens up the other 99.9%?Dr. Olga Nissan, Ph.D. is Vice President of ...
Programming Biology: Inside the DNA Supply Chain Powering Modern Drug Discovery - Dr. Patrick Finn, Ph.D. - President & COO -Twist Bioscience
We used to think of DNA as something we read. Now we’re starting to treat it like something we write - and that changes everything about how medicine gets made.Dr. Patrick Finn, Ph.D. is President and COO of Twist Bioscience ( https://w...
The Hidden Ripple Effect of Saving a Life | Brad & Kiera Newbury - National Medical Education & Training Center Inc.
What if saving a life isn’t a single moment…but the beginning of thousands of future moments that only exist because someone chose to act?Today’s guests are father-daughter duo Brad Newbury ( https://bradnewbury.com/ ) and Kiera Newbury...
The Future of Aging: From Healthspan to Joyspan | Dr. Sanjay Shetty, MD - President, CenterWell/Humana & Dr. Kerry Burnight, Ph.D. - Author, Joyspan
For decades, medicine focused on helping us live longer. Then came healthspan - helping us stay healthier longer. But what if the next frontier is something even deeper: joyspan… the quality, meaning, and fulfillment of the years we actually li...
Why Longevity Medicine Is Shifting From Optimization to Disease Interception | Dr. Julie Chen, MD - Chief Medical Officer - Radence and Sidestep Health AI
What if the future of medicine isn’t about treating disease…but detecting it 20 years before symptoms ever appear? Dr. Julie Chen, MD is helping lead one of the newest precision-health companies trying to build that future.Dr. Julie Che...
Induced Proximity Meets Oncology: A New Era In Cancer Therapy | Dr. Angela Coxon, Ph.D., Vice President of Research and Development, Amgen
For more than 30 years, small cell lung cancer has remained one of the most aggressive and difficult-to-treat cancers - marked by rapid progression, high relapse rates, and very few meaningful advances. But that may finally be starting to chang...
How Psychedelic Biotech Is Reshaping Mental Health | Eric So - CEO, Helus Pharma
Psychedelic medicine is no longer fringe science - it’s now part of White House policy discussions, FDA fast-track programs, and a rapidly emerging neuropsychiatric industry. But can these therapies truly become scalable standards of care?<...
Space Pharma: The Next Frontier in Biotechnology | Dr. Katie King - CEO, BioOrbit
What if the next breakthrough cancer therapy can’t be manufactured on Earth at all?In this episode, BioOrbit CEO Dr. Katie King explains how microgravity may unlock entirely new classes of medicines - from ultra-precise biologics to can...
How Smartphones Are Rewiring Our Brains, Sleep & Attention | Dr. Nidhi Gupta, MD - Founder, Phreedom Foundation; Founder, KAP Pediatric Endocrinology
What if the biggest public health threat to attention, sleep, relationships, and mental health isn’t a virus or a disease - but the device in your pocket?Dr. Nidhi Gupta, MD ( https://reconnect.expert/Dr-Nidhi-Gupta ) is a pediatric end...
A New Hope for Newborn Brain Injury - Dr. Howard Berman, Ph.D. - CEO, ReAlta Life Sciences
Every year, thousands of newborns suffer devastating brain injury during birth - and despite decades of research, there are still no approved drug therapies for Hypoxic Ischemic Encephalopathy (HIE). But one biotech company believes it may fina...
Inside America’s Homeless Crisis: Policy, Reality & the Stories We Ignore - Donald Whitehead Jr. - Executive Director, National Coalition for the Homeless; Valerio Zanoli - Award-Winning Filmmaker and Social Entrepreneur
On any given night, more than 750,000 people are homeless in America - but that number doesn’t even begin to tell the full story.Today’s conversation sits at the intersection of advocacy, lived experience, and storytelling - because end...
How Chef-Led Customization Is Disrupting The Chocolate Industry - Brandon Olsen And Michael Held - Co-Founders - As We Do Chocolate Company
There’s a hidden supply chain crisis happening in fine dining right now - and it’s something as simple, and as essential, as chocolate.Brandon Olsen is a world-class chef and chocolatier known for blending high-end culinary artistry wit...
Microreactor Revolution: Nuclear Power Goes Small, Mobile, and Off-Grid - Josef Freundorfer - CEO - Nuclea Energy
What if you could ship a nuclear power plant like a container - and run it for years without refueling?Josef Freundorfer is the CEO of Nuclea Energy ( https://www.nuclea.energy/ ), where he is leading the development of next-generation ...
How AI + Satellites Are Transforming Global Infrastructure Monitoring | Sean Donegan - CEO - Satelytics
We may be building something entirely new - a kind of digital nervous system for the planet, where satellites and AI are constantly sensing and interpreting what’s happening on Earth.Sean Donegan is the Founder and CEO of Satelytics ( h...
Prescribing Nature For Human And Planetary Health - Jennie McCaffrey - Vice President of Health & Education - BC Parks Foundation
Doctors in North America are now prescribing something you can’t buy at a pharmacy… and it’s backed by a growing body of science. Jennie McCaffrey is the Vice President of Health & Education at the BC Parks Foundation ( https:/...
Non-Pharmacological Cognitive Health: The StrongerMemory Approach | Rob Liebreich - CEO, Goodwin Living
Today on Progress, Potential And Possibilities, we explore a different kind of breakthrough in cognitive health - not a drug, not a device, but a simple daily practice that’s quietly transforming lives.Our guest is Rob Liebreich, Presid...
Bioprinting The Human Body In Wartime | Ukraine’s Medtech Revolution | Denys Gurak, Founder; Kateryna Osetrova, Executive Director; Michael Pluzhnyk, Chief Technology Officer; biodrook
In times of crisis, innovation doesn’t slow down - it accelerates.Over the past several years, Ukraine has become globally recognized for its rapid advances in defense technology - particularly in drones and distributed manufacturing. B...
Building “Off-the-Shelf” Regenerative Cell Therapies: The Next Biotech Revolution | Brian Culley - CEO, Lineage Cell Therapeutics
Today’s conversation sits at the intersection of one of the most ambitious - and most challenging - frontiers in modern medicine: regenerative cell therapy.For decades, the vision has been incredibly compelling - replace damaged or dyin...
Bioelectronics & Precision Neuromodulation: The Next Therapeutic Frontier | Dr. Robert Spoelgen, Ph.D. - Vice President and Head of Bioelectronics, Merck KGaA Darmstadt Germany
Imagine a device that can sense disease in real time… and treat it instantly. That’s the promise of Bioelectronics.Dr. Robert Spoelgen, Ph.D. is Vice President and Head of Bioelectronics at Merck KGaA Darmstadt Germany ( https://www.emd...
The Architecture of a Drug Empire - and the Systems It Forced the World to Build | Carlos Lehder
Today’s conversation is part of a new series we’re launching — ‘Past Forward: Lessons for the Next Century.’ In this series, we examine pivotal moments, systems, and individuals from the past - not to relive them, but to better und...
The Blood Test That Could Detect Alzheimer’s Years Before Symptoms | Mike Banville - CEO, ALZpath
What if a simple blood test could detect Alzheimer’s years—maybe even decades—before symptoms ever appear?Mike Banville is the Chief Executive Officer of ALZpath ( https://alzpath.bio/ ), a company at the forefront of transforming how A...
How Microbiome Data is Transforming Veterinary Medicine | Dr. Bushra Schuitemaker, Ph.D. - Head of Microbiology, Pooch & Mutt - Head of Science and Research, BIOME9
There’s a revolution happening in pet health right now - where a simple stool sample can reveal disease risk, immune health, and even how long your dog might live.Dr. Bushra Schuitemaker, Ph.D. is a microbiologist, zoologist, and scienc...