Dr. Christopher Buck, Ph.D. - Senior Investigator, Laboratory of Cellular Oncology / Head, Tumor Virus Molecular Biology Section, Center for Cancer Research, National Cancer Institute - Food-Based Oral Vaccines And Disease Prevention

Dr. Christopher Buck, Ph.D. ( https://cbuck.substack.com/ ) is Senior Investigator, Laboratory of Cellular Oncology, And Head, Tumor Virus Molecular Biology Section, Center for Cancer Research, at the U.S. National Cancer Institute ( https://ccr.cancer.gov/staff-directory/christopher-b-buck ).

Dr. Buck’s lab focuses on the virion proteins of a family of viruses called polyomaviruses, and their research ranges from basic investigation of the mechanisms through which polyomaviruses infect cells to translational development of virus-like particle vaccines. They also maintain an active interest in discovering new virus species, with the goals of uncovering human disease associations and understanding the evolutionary history of cancer-causing viruses.

Dr. Buck received a bachelor’s degree in Molecular Cellular and Developmental Biology from the University of Colorado at Boulder and a Ph.D. from the Johns Hopkins School of Medicine.  

Dr. Buck’s graduate research in Dr. Robert Siliciano's lab focused on the translation and immunogenicity of the HIV-1 capsid protein Gag. For his graduate work, Dr. Buck received the Alicia Showalter Reynolds Award. 

In 2001, Dr. Buck began post-doctoral training in the Lab of Cellular Oncology, where he developed systems for producing human papillomavirus (HPV)-based gene transfer vectors (pseudoviruses). His work using HPV vectors ranged from basic studies of HPV virion structure and morphogenesis to translational research identifying candidate topical microbicides for blocking HPV transmission. For his work in these areas, Dr. Buck, and his mentors, Drs. John Schiller and Doug Lowy, shared the 2006 Norman P. Salzman Award. 

In 2007, Dr. Buck joined the faculty of the NCI’s Center for Cancer Research as an Investigator. In 2013, he shared a second Salzman Award in recognition of his mentoring of Dr. Rachel Schowalter.  Dr. Buck was awarded tenure in 2014.

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