Mind & Matter
Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it.
The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today.
Not medical advice.
At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it.
As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet.
I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint.
My beliefs:
- Taking ownership of your health starts with taking ownership of your information diet.
- All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions.
- Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information.
Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi:
- “Γνῶθι σεαυτόν” (Know thyself)
- “Μηδὲν ἄγαν” (Nothing in excess)
- “Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)
Mind & Matter
Latest Episodes
Endocannabinoid Biology in Health & Disease | Nephi Stella | Episode 305
The biology of endogenous cannabinoids & history of cannabinoid-based therapeuticsTOPICS DISCUSSED:Anandamide vs 2-AG: The two major endocannabinoids with a shared arachidonic acid backbone but distinct head...
Mitochondria Peptides: MOTS-c, Humanin, Genetic Variation in Health & Disease | Pinchas Cohen | Episode 304
Mitochondrial peptides act as stress signals that regulate metabolism, muscle mass, and neurodegeneration.TOPICS DISCUSSED:Mitochondria as Communication Hubs: Beyond ATP production, mitochondria encode peptides ...
Neuro-Immune Interactions: Pain, Inflammation, Peptides & Healing | Isaac Chiu | Episode 303
How the nervous and immune systems communicate, using peptides and other signals, to regulate pain, itch, and inflammation.TOPICS DISCUSSED:Nociception & Pathogens: Sensory neurons detect bacterial toxins wi...
MOTS-c & Mitochondrial Peptides in Health & Aging | David Lee | 302
Mitochondrial peptide MOTS-c is a stress-induced signal that reprograms cell metabolism.TOPICS DISCUSSED:Mitochondrial Roles: Not just ATP production, but “speaker of the house” via communication molecules that ...
Peptides & GHK-Copper in Skin Health | Rahi Sarbaziha | Episode 301
GHK-Copper and peptides in skin care, aging, and general health.TOPICS DISCUSSED:Endogenous Decline: GHK-copper levels peak in young adulthood then fall with age, reducing natural support for skin repair and col...
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