Alexander Disease Research Update
Albee Messing
Monthly discussion of recent publications from the research literature on Alexander Disease, hosted by Albee Messing from the University of Wisconsin-Madison.
Episodes
Alexander Disease Research Update - Episode #14: whole exome/genome sequencing; more questions on the brainstemNovember 12, 2022
Alexander Disease Research Update - Episode #13: MRI diffusion tractography - what can it tell us?October 13, 2022
Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsiesSeptember 01, 2022
Alexander Disease Research Update - Episode #11: neurology 101 (location, location, location), discussion on the autonomic nervous systemAugust 05, 2022
Alexander Disease Research Update - Episode #10: effects of variants in the rod domain on GFAP assembly and aggregation, new ideas about functions of intermediate filamentsJune 09, 2022
Alexander Disease Research Update - Episode #9: new mechanisms of astrocyte dysfunction, case report with novel variant, commentary on head trauma as an aggravating factorApril 12, 2022
Alexander Disease Research Update - Episode #8 - two case reports, natural history study of 21 pediatric patients, management of constipationMarch 06, 2022
Alexander Disease Research Update - Episode #7 - common drugs tested in cell culture model; germline mosaicism vs de novo variants; electronic health records in researchJanuary 27, 2022
Alexander Disease Research Update - Episode #6 - silent mutations, case report, new rat model, mouse proteomicsJanuary 04, 2022
Alexander Disease Research Update - Episode #5 - case report with silent mutation and area postrema syndrome; neuropsychological testingDecember 04, 2021
Alexander Disease Research Update - Episode #4 - case report, clinical trialsOctober 26, 2021
Alexander Disease Research Update - Episode #3September 16, 2021
Alexander Disease Research Update - Episode #2August 13, 2021
Alexander Disease Research Update - Episode #1July 15, 2021
Alexander Disease Research Update - Episode #13: MRI diffusion tractography - what can it tell us?October 13, 2022
Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsiesSeptember 01, 2022
Alexander Disease Research Update - Episode #11: neurology 101 (location, location, location), discussion on the autonomic nervous systemAugust 05, 2022
Alexander Disease Research Update - Episode #10: effects of variants in the rod domain on GFAP assembly and aggregation, new ideas about functions of intermediate filamentsJune 09, 2022
Alexander Disease Research Update - Episode #9: new mechanisms of astrocyte dysfunction, case report with novel variant, commentary on head trauma as an aggravating factorApril 12, 2022
Alexander Disease Research Update - Episode #8 - two case reports, natural history study of 21 pediatric patients, management of constipationMarch 06, 2022
Alexander Disease Research Update - Episode #7 - common drugs tested in cell culture model; germline mosaicism vs de novo variants; electronic health records in researchJanuary 27, 2022
Alexander Disease Research Update - Episode #6 - silent mutations, case report, new rat model, mouse proteomicsJanuary 04, 2022
Alexander Disease Research Update - Episode #5 - case report with silent mutation and area postrema syndrome; neuropsychological testingDecember 04, 2021
Alexander Disease Research Update - Episode #4 - case report, clinical trialsOctober 26, 2021
Alexander Disease Research Update - Episode #3September 16, 2021
Alexander Disease Research Update - Episode #2August 13, 2021
Alexander Disease Research Update - Episode #1July 15, 2021