Recently CSA Vital Times published a poignant first-person account by Dr. Zeest Khan, cardiac anesthesiologist, of her struggles with #LongCOVID. This is a follow-up, with Drs. Khan and Wes Ely, MD, a prominent critical care medicine specialist at Vanderbilt University and leader in ICU delirium management, who is now directing efforts in Long COVID. They sit down to discuss the therapeutic approaches. Follow Dr. Wes Ely on Twitter @WesElyMD and Dr. Zeeest Khan at @doctor_zeest.