Dive into Imaging Science
This is the Podcast of the European Society for Molecular Imaging (ESMI).
Join us as we delve into the recent literature, and perhaps learn a little from the minds that have shaped the field.
The premise is really simple: Each time we invite one senior academic to discuss their favourite publication from the recent literature. We’ll find out what caught their eye, and why it is worth taking a closer look at this particular publication. Along the way, we will learn their publication strategies and possibly even glimpse into the future of this amazing field of research.
Music “In this Life”, Composer: Guido Jäger, Musicians: Andreas Jacobs – violin, Jacob Niller – accordion, Wolfgang Platen – contrabass
Dive into Imaging Science
In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors
- GUEST: Markita Del Carpio Landry, UC Berkeley
Welcome to Episode 16 of “Dive into Imaging Science”!
🎧 Tune in for a dynamic discussion on innovative probes work, the function of dopamine in the brain, and how these new imaging tools can be used in the future to reveal new biology.
This episode features a truly special guest: Markita Del Carpio Landry, the inaugural Trailblazer Plenary Lecturer at the upcoming EMIM in Ljubljana next March!
"The Trailblazer Lecture celebrates a rising leader in imaging science whose trajectory is unmistakably pointing toward lasting impact and excellence at the highest level. Markita is a perfect fit for such an accolade."
In the Landry lab, they have pioneered synthetic bio-mimetic nanocomposites for fluorescence imaging and targeted delivery of biological cargoes.
We talk with Markita about her career path, about the excitement to develop new imaging tools, and how gaining an academic position gave her the freedom to explore biological questions. We also discuss the importance of collaboration in science.
🎯 The paper Markita selected for this episode, from Yulong Li’s lab and published in Science, features a sophisticated molecular sensor that reads out dopamine signalling in the brain via far-red fluorescence.
The group describes how this innovative new tool can be multiplexed with other fluorescent readouts of acetylcholine and cyclic AMP. Starting in cells, before progressing to tissue sections, zebrafish, and finally in living mice, they demonstrate the ability to detect multiple neurochemicals simultaneously – quite a feat!
🍸 For this episode a cocktail to celebrate the inauguration of the trailblazer lectures and invites to our podcast. The Champagne Cocktail.
Recipe: A sugar cube in a flute glass, coated with Angostura bitters, then a shot of Cognac and top up with Champagne. A twist to the most loved celebration drink!
Selected Publication: Yu Zheng et al. In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors. Science 388, eadt7705(2025). DOI:10.1126/science.adt7705
Further information on the European Society for Molecular Imaging:
https://e-smi.eu/
Contact: office@e-smi.eu
