Reproductive Rebel

Stronger Through the Shift: The Science of Creatine for Perimenopause, Nervous System and Longevity with John Moro

Adrienne Irizarry, HWH Season 5 Episode 36

Use Left/Right to seek, Home/End to jump to start or end. Hold shift to jump forward or backward.

0:00 | 51:25

Perimenopause is not just a hormonal shift—it’s a full-body recalibration that impacts your brain, metabolism, and nervous system.

In this episode of Reproductive Rebel, we explore one of the most overlooked yet well-researched tools in women’s health: creatine.

Joined by John Morro, we unpack the science behind creatine supplementation and why it’s emerging as a powerful ally for women navigating perimenopause and beyond.

This conversation bridges the gap between research and real-life application—offering a grounded, expansive perspective on strength, longevity, and cellular energy.

In This Episode, We Explore:

– What creatine actually is and how it works in the body

– Why women in perimenopause may benefit more than ever

– The connection between creatine, brain function, and mood

– Muscle as a key player in hormonal and metabolic health

– Nervous system resilience and energy production

– Common myths about creatine (and what’s actually true)

– How to begin incorporating creatine safely and effectively


This Episode Is For You If:

– You’re experiencing fatigue, brain fog, or decreased strength

– Your current wellness routine no longer feels supportive

– You want evidence-based tools that honor your body’s evolution

– You’re ready to move from depletion → resilience

Reproductive Rebel Takeaway:

Perimenopause isn’t asking you to do more.

It’s asking you to support yourself differently.

And sometimes, that looks like reclaiming tools the wellness world told you weren’t “for you.”

https://www.sciencedirect.com/topics/neuroscience/brain-metabolism

https://pmc.ncbi.nlm.nih.gov/articles/PMC7998865/#:~:text=Implications%20of%20creatine%20supplementation%20and,the%20luteal%20phase%20%5B16%5D.

(Creatine Kinase activity reference)

https://link.springer.com/article/10.1007/s00726-016-2199-y

(Creatine in women)

https://www.tandfonline.com/doi/full/10.1080/15502783.2025.2502094

(Creatine in menopause)

https://pubmed.ncbi.nlm.nih.gov/8730112/#:~:text=According%20to%20a%20study%20of%20patients%20with,atrophy%20explain%20only%20part%20of%20the%20association.

(Impaired creatine kinase activity effects.)

https://pmc.ncbi.nlm.nih.gov/articles/PMC5928444/#:~:text=The%20addition%20of%20creatine%20to,leads%20to%20accelerated%20bone%20loss.

(Creatine and bones)

https://pmc.ncbi.nlm.nih.gov/articles/PMC8228369/

Info on creatine and exercise

https://link.springer.com/article/10.1186/s12970-021-00412-w

(Myth busting and creatine)

Moon Essence®: Holistic solutions for a symptom free life.

Join The Rebel Frequency Inner Circle to unlock bonus episodes and content from the Reproductive Rebel herself*

Our FREE Facebook community, Ancient Wisdom for the Modern Woman!

Book with Moon Essence®

Instagram, Facebook and Twitter: @moonessenceme

“Hard Lotion” is a lotion “bar", solid at room temperature, made with 3 ingredients (shea butter, coconut oil & beeswax). Designed to heal & protect hands & feet from cracked & extremely dry skin. Use code "RR" now for 20% off

Leave a Review! Help others find this helpful information.

People on this episode