DMPK Insights
DMPK Insights is a by-monthly podcast by Pharmaron about the latest research and developments in DMPK science with a focus on three different areas:- Current Considerations: Breaking DMPK science with a focus on recent scientific publications, regulatory and other considerations - Influential Individuals: Key DMPK scientific influencers – career path, research focus, future plans- Trending Technologies: Technological advances in DMPK science – what does it do and why is it needed?
Episodes
12 episodes
DMPK Insights #12: New Frontiers in Understanding the BBB Transport of Small Molecule Drugs
For a captioned version or to access the transcript, please visit: https://www.pharmaron.com/knowledge-center/dmpk-insights-12-bbb-transporters/In this podcast, Elena and Mikko will discuss the current state-of-the-art around transporter...
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Season 1
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Episode 12
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38:41
DMPK Insights #11: Drug Meets Bug: How the Gut Microbiome Shapes DMPK
For a captioned version or to access the transcript, please visit https://www.pharmaron.com/knowledge-center/dmpk-podcast-11-gut-microbiome/.In this podcast, Chris Bode (Pharmaron US Labs) interviews Peter Turnbaugh, a microbiologist and...
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Season 1
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Episode 11
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47:27
DMPK Insights #10: The DMPK Project Representative: An essential role of contribution, integration and evolution
In this podcast Simon Taylor (Pharmaron UK) interviews Kevin Beaumont, a highly experienced DMPK scientist, leader and drug developer who has lived and breathed the role of the DMPK Project Representative throughout his 40-year industrial caree...
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Season 1
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Episode 10
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47:36
DMPK Insights #9: 60 and Beyond: Navigating the Frontiers of PBPK and QSP
In this podcast, listeners will join us in celebrating the remarkable career of Professor Amin Rostami, a trailblazer in the realms of PBPK and QSP. Following his 60th birthday, Professor Rostami will provide insights into his journey, the dyna...
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Season 1
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Episode 9
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39:32
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DMPK Insights #8: It’s “All-go” with Oligos: Challenges and Opportunities in LC-MS of Therapeutic
In this podcast, Robert MacNeill, Professor Michael Bartlett of the University of Georgia and Dr. Guilherme Guimaraes of Biogen, will focus on oligonucleotide LC-MS covering the exciting key challenges, the pivotal nature of sensitivity in such...
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Season 1
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Episode 8
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27:04
DMPK Insights #7: Carboxylic Acids and DILI – Conjugation and Reputation
In this podcast, Professor Ian Wilson, a globally recognised and leading expert in drug metabolism, with over 500 publications in the field, takes us on an engaging journey exploring the link between carboxylic acid containing drugs and their i...
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Season 1
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Episode 7
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33:32
DMPK Insights #6: Protein Mass Spectrometry: Advancing the Bioanalysis of Biotherapeutics and Biomarkers
In this podcast, Scott and John will discuss the LC-MS techniques that have been applied for the bioanalysis of biotherapeutics.The episode explores the following:The impact that mass spectrometry is having in the bio...
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Season 1
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Episode 6
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39:33
DMPK Insights #4: DMPK Past, Present and Future – A Festive Tale
This podcast format is inspired by the Charles Dicken’s novella “A Christmas Carol” whereby Phil Jeffrey (Bicycle Therapeutics), Beth Williamson (UCB) and Daniel Price (Nimbus) discuss DMPK Past, Present and Future with Scott. Key element...
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Season 1
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Episode 4
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1:03:36
DMPK Insights #5: Mass Spectrometry Imaging - Past, Present and Future
In this podcast, Josephine Bunch, Principal Research Scientist and Co-Director of the National Centre of Excellence in Mass Spectrometry (NiCE-MSI) at NPL, talks about her work, and in particular her involvement in the Cancer Research UK ...
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Season 1
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Episode 5
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30:38
DMPK Insights #3: Free Drug Theory: No Longer Just a Hypothesis?
In this podcast, Scott Summerfield, Senior Director, Pharmaceutical Metabolism at Pharmaron discusses his recent publication on Free Drug Theory (FDT) with Simon including the principles, arguments, and project impact. This article was an invit...
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Season 1
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Episode 3
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36:15
DMPK Insights #2: Pathways to Successful Drug Design – Discovery Metabolite ID
In this podcast, Dan Weston, Scientific Leader, Biotransformation at GSK discusses his recent publication on the important role that Metabolite ID plays in drug discovery.The episode addresses the following questions:Why stud...
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Season 1
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Episode 2
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26:43
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DMPK Insights #1: Candidate Survival – 3 Pillars to 5Rs and Beyond
In this podcast, Dr. Paul Morgan, Head of DMPK at Grünenthal Group, discusses the development of the publication that introduced the “5R framework” and improved the likelihood of AstraZeneca candidate survival from candidate drug nomination to ...
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Season 1
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Episode 1
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45:41
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