ICU Ed and Todd-Cast
Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine and have special guests talking about their area of expertise! This podcast is made for educational purposes. The content provided in this podcast, and in any linked materials, is not intended and should not be construed as medical advice and should not be used to diagnose or treat any medical condition. We try to stay away from opinions but all opinions represent our own and not of any entity we work for. Please keep this in mind as you enjoy the podcast!
Episodes
75 episodes
CCR25: UK-ROX and TARGET-Protein (with Mail bag!)
Episode 72! We continue talking about the articles from the CCR25 conference with UK-ROX or "Conservative Oxygen Therapy in Mechanically Ventilated Critically Ill Adult Patients" published in JAMA 2025 by Martin et al and TARGET-Protein or "Sod...
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Season 1
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Episode 72
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44:27
CCR24/Old: FLUID and BICAR-ICU
Episode 71! We continue talking about the articles from the CCR25 conference with FLUID or "A Crossover Trial of Hospital-Wide Lactated Ringer's Solution versus Normal Saline" published in NEJM 2025 by McIntyre et al and our old article is BICA...
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Season 1
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Episode 71
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53:35
New: A2B with Wes Ely
Episode 70! In this episode we have a special guest, Wes Ely, join us to talk about A2B or "Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients" by Walsh et al published in JAMA May of 2025. A long dis...
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Season 1
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Episode 70
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58:30
CCR25: RESCUE-3 and PROMIZING
Episode 69! We start talking about the articles from the CCR25 conference with RESCUE-3 or "Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation" published in AJRCCM by Dres et al and PROMIZING or "Proportion...
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Season 1
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Episode 69
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44:57
New: MODE with Kevin Seitz
Episode 68! Today we talk about modes of mechanical ventilation with the first author Dr. Kevin Seitz. This was published in CHEST April of 2025 as "Effect of Ventilator Mode on Ventilator-Free Days in Critically Ill Adults: A Randomized Clinic...
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Season 1
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Episode 68
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50:22
CCR25 Recap
Episode 67! Today we do a quick overview of the presentations from the Critical Care Reviews 2025 (CCR25) Conference!
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Season 1
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Episode 67
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42:57
New: TASC with Benjamin Tillman
Episode 66! Today we talk about Acute Chest Syndrome in Sickle Cell Disease with one of our favorite hematologists, Benjamin Tillman! We base our discussion around the TASC trial or "Comparison of Prophylactic and Therapeutic Doses of Anticoagu...
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Season 1
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Episode 66
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46:05
New/Old: Risk factors for Stress Ulcers and Transfusions in GIB
Episode 65! Though this is during ATS, this episode was pre-recorded so you will get some reactions to the conference in the coming episodes. Instead we have a short episode where we talk about risk factors for stress ulcers and transfusion thr...
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Season 1
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Episode 65
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35:14
New: REMAP-CAP Steroids
Episode 64! We talk more about steroids in severe community acquired pneumonia with "Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial" pub...
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Season 1
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Episode 64
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40:02
New/Old: PEERLESS and PEITHO
Episode 63! We talk about intermediate risk PE in "Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in the Management of Intermediate-Risk Pulmonary Embolism" by Jaber et al published in Circulation in February 2025. The...
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Season 1
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Episode 63
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50:27
ISICEM Review and SESAR
Episode 62! We talk briefly about two of the analyses that dropped with the ISICEM conference and then talk in depth about SESAR or "Inhaled Sedation in Acute Respiratory Distress Syndrome" by Jabudon et al in JAMA 2025. Then was answer a quest...
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Season 1
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Episode 62
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48:46
New/Review: Extubating to HFNC
Episode 61! We talk about HFNC including extubation to HFNC in "Early weaning from invasive mechanical ventilation via high-flow nasal oxygen versus conventional weaning in patients with hypoxemic respiratory failure" by Ayyawar et al published...
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Season 1
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Episode 61
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46:47
SCCM: PROACTIVE and ASA in sepsis
Episode 60! We jump to SCCM where we talk about 2 late breakers - PROACTIVE or "Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation" by Downar et al and "Acetylsalicylic Acid Tr...
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Season 1
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Episode 60
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45:15
TRAUMOX2, SAHARA, and mailbag
Episode 59! We finish our CCR down under coverage with TRAUMOX2 or "Early Restrictive vs Liberal Oxygen for Trauma Patients" published in JAMA by Arleth et al and then switch to SAHARA or "Liberal or Restrictive Transfusion Strategy in Aneurysm...
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Season 1
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Episode 59
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57:02
Old/New: FLORALI and RENOVATE
Episode 58! We talk about non-invasive oxygen support and RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published in JAMA December 2024 and presented at the CCR Down Under Conference....
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Season 1
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Episode 58
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56:42
CCR Down Under: SCREEN with Adam Wright
Episode 57! We were excited to have on this episode Dr. Adam Wright who is a PhD in Bioinformatics to discuss SCREEN or "Electronic Sepsis Screening Among Patients Admitted to Hospital Wards: A Stepped-Wedge Cluster Randomized Trial" published ...
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Season 1
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Episode 57
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1:06:27
CCR Down Under: ADAPT-Sepsis
Episode 56! In this episode we spend a few minutes talking about making decisions on ECMO initiation but spend most of the episode talking about ADAPT-Sepsis or "Biomarker-Guided Antibiotic Duration for Hospitalized PatientsWith Suspected S...
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Season 1
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Episode 56
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46:03
2024 Year in Review and CCR Down Under
Episode 55 and Happy New Year! In this episode we talk broad strokes about the CCR Down Under Conference and the trials that were presented, then Todd and Eddie go over a bunch of articles from the year 2024 that they didn't have time to go ove...
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Season 1
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Episode 55
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59:58
New/Old: BALANCE and iDIAPASON
Episode 54! In this episode we talk about antibiotic duration in bacteremia (BALANCE) and also antibiotic duration in Pseudomonas Ventilator associated pneumonia (iDIAPASON). BALANCE (NEJM): https://www.nejm.org/doi/full/10.1056/NE...
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Season 1
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Episode 54
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52:01
New/New-ish: IVIO and PARAMEDIC-3
Episode 53! In this episode we talk about access in patients with out of hospital cardiac arrest. Both articles are similar so we talk in depth about IVIO and then bringing PARAMEDIC-3 to round out our discussion. A good acronym discussion too,...
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Season 1
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Episode 53
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34:16
New/New: INTREPID and PROLABI
Episode 52! In this episode we talk about fevers in acute neurologic injury and double that up with talking about low tidal volume ventilation in patients with neurologic injuryINTREPID (JAMA): https://jamanetwork.com/journals/jama/full...
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Season 1
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Episode 52
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40:42
LIVE @ CC Bootcamp 2024: NONSEDA
We are (were) LIVE at ACNP Critical Care Bootcamp 2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the NONSEDA trial or "Nonsedation or Light Seda...
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Season 1
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Episode 51
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22:32
FAST and IV Fluid Shortage
Episode 50! In this episode we talk about SBT frequency and "Frequency of Screening and Spontaneous Breathing Trial Techniques" by Burns et al from JAMA 2024 that was released with the ESICM conference. In our second segment, instead of another...
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Season 1
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Episode 50
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55:49
LIVE @ CHEST2024: Minocycline for delirium and Amio vs lido for cardiac arrest
We are LIVE at CHEST2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about a few articles that were recently published in CHEST - "Prophylactic Minocycl...
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Season 1
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Episode 49
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52:10
New: Long Term Outcomes of ICU Visitation Policies
Episode 48! In this episode we talk about the long term effects of ICU visitation policies on families. Long Term Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39172240/Long Term Outcomes of Visitation (ICM):...
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Season 1
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Episode 48
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35:26