In this episode of Dark History, we revisit one of the most infamous studies in clinical research — the Tuskegee Syphilis Study. While nearly every researcher has heard of it as the cornerstone example of why IRBs exist, the deep...

 In this episode, we dive into a chilling case where a promising T-cell therapy showed remarkable results in adolescents and pediatric patients — but when tested in adults, the outcome was tragically different. Phase 1 looked fine, Phase 2...

“Good Intentions, Bad Paperwork” Meet the city doc everyone loved — champion of public health, hero of harm reduction, and the driving force behind making Narcan accessible without a prescription. But when his passion for helping peo...

In this powerful installment of Dark History of Clinical Trials, we examine one of the most tragic and transformative episodes in pharmaceutical history: the thalidomide disaster.Marketed as a safe sedative and morning sickness ...

In this episode, we dive deep into the recent FDA action that exposed a pharmaceutical manufacturer distributing counterfeit codeine cough syrup. What began as a quiet compliance concern quickly escalated into a full-scale investigation—leading...