Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, ...

Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the interse...

Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therap...

Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent per...

Lars Svensson, MD, PhD, and Xiaoying Lou, MD, share a deep dive into valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms.Looking to refer a patient? Please r...

Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides,...

A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategi...

Kenneth McCurry, MD, and Marie M. Budev, DO, discuss Cleveland Clinic’s leadership in lung and multi-organ transplantation, highlighting innovations like ex vivo lung perfusion (EVLP) and the collaborative care model that supports complex trans...

Tamanna Singh, MD, and Amanda Vest, MBBS, discuss the relationship between obesity and heart failure. They discuss multidisciplinary strategies, including lifestyle interventions and pharmacologic therapies like GLP-1 receptor agonists for mana...

Donna Kimmaliardjuk, MD, and Faisal Bakaeen, MD, explore the latest in multi-arterial coronary artery bypass grafting (CABG). They discuss patient selection, surgical techniques and long-term outcomes supported by optimal medical therapy. ...

When a heart is weak after a heart attack, cardiac arrest or surgery, mechanical circulatory support (MCS) can help the heart function while it heals or assist patients long-term.  Cleveland Clinic experts discuss MCS devices, specifically...

Amanda Vest, MBBS, explores sex-based differences in heart failure, focusing on biological and social factors that influence disease development, treatment response and outcomes in women. She highlights disparities in risk factors, access to ca...

Scott Cameron, MD, highlights the underdiagnosis and undertreatment of peripheral artery disease (PAD) in women. He discusses diagnostic challenges and emphasizes the  need for improved screening, female-specific guidelines and more inclus...

Women are more likely than men to experience atrial fibrillation symptoms. Mohamed Kanj, MD, discusses gender-based differences in atrial fibrillation treatment, including rate control, rhythm control and anticoagulation. Looking t...

Ravi Ambani, MD, and Aravinda Nanjundappa, MBBS, MD, discuss Cleveland Clinic’s leadership and progress in treating carotid artery disease. Learn how multidisciplinary teams are transforming care with new research on medical and surgical therap...

Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension caused by chronic blood clots in the lungs. It is an under-recognized condition, but with accurate imaging and quality treatment, it can often be cured. G...

When treating mitral valve disease, a surgeon must decide whether to repair or replace a valve. Cleveland Clinic experts discuss robotically-assisted surgery, reoperations and the outcomes a patient can expect from surgery at Cleveland Clinic.<...

Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss surgical options, recovery and expected outcomes for those with connective tissue...

Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss the diagnosis of these genetic conditions and indications for heart and aorta tre...

G. Jay Bishop, MD, and Aravinda Nanjundappa, MBBS, MD, explore Cleveland Clinic’s latest advances in vascular medicine, from research on aortic aneurysm biomarkers to innovative treatments for pulmonary embolism, hypertension, and peripheral ar...

Learn about the promising results of a fixed-dose combination therapy trial that achieved up to a 50% reduction in LDL cholesterol. Steven Nissen, MD and Ashish Sarraju, MD discuss how this CETP inhibitor-based therapy compares to monotherapies...

Persistent or recurrent atrial fibrillation (AFib) following ablation remains a clinical challenge, especially when it occurs more than three months after an ablation. Expert Cleveland Clinic electrophysiologists discuss the causes for recurren...

Structural heart disease encompasses a range of abnormalities affecting the heart’s valves, chambers, and muscle. At Cleveland Clinic, our team brings deep expertise in the diagnosis and interventional management of these complex conditions—par...

When an aortic aneurysm occurs, a multidisciplinary team of experts can provide the best care for the patient. Francis (Frank) Caputo, MD, and Marijan Koprivanac, MD, discuss aortic aneurysms and the team-based approach to treating these comple...

Bicuspid aortic valve is a common heart condition where the aortic valve has only two leaflets instead of the normal three. In part two of this two-part series, Lars Svensson, MD, PhD, and Brian Griffin, MD, discuss surgical techniques for bicu...