Learn about the promising results of a fixed-dose combination therapy trial that achieved up to a 50% reduction in LDL cholesterol. Steven Nissen, MD and Ashish Sarraju, MD discuss how this CETP inhibitor-based therapy compares to monotherapies...

Persistent or recurrent atrial fibrillation (AFib) following ablation remains a clinical challenge, especially when it occurs more than three months after an ablation. Expert Cleveland Clinic electrophysiologists discuss the causes for recurren...

Structural heart disease encompasses a range of abnormalities affecting the heart’s valves, chambers, and muscle. At Cleveland Clinic, our team brings deep expertise in the diagnosis and interventional management of these complex conditions—par...

When an aortic aneurysm occurs, a multidisciplinary team of experts can provide the best care for the patient. Francis (Frank) Caputo, MD, and Marijan Koprivanac, MD, discuss aortic aneurysms and the team-based approach to treating these comple...

Bicuspid aortic valve is a common heart condition where the aortic valve has only two leaflets instead of the normal three. In part two of this two-part series, Lars Svensson, MD, PhD, and Brian Griffin, MD, discuss surgical techniques for bicu...

Bicuspid aortic valve is a common heart condition where the aortic valve has only two leaflets instead of the normal three. In part one of this two-part series, Lars Svensson, MD, PhD, and Brian Griffin, MD, discuss treatment options for managi...

Venugopal Menon, MD, Section Head of Clinical Cardiology , spotlights new Cleveland Clinic research presented at ACC 2025. Explore the highlights of six studies on topics like antiplatelet therapy, fungal endocarditis, mechanical circulatory su...

Cleveland Clinic is transforming hypertrophic cardiomyopathy (HCM) care through new clinical trial innovations. Milind Desai, MD, MBA, recaps two recent studies that analyzed the use AI for the diagnosis of HCM and gene therapy for treatment.

Cleveland Clinic's dedication to research and a team of teams approach puts the Heart, Vascular and Thoracic Institute at the forefront of heart failure care. Amanda Vest, MBBS, and Edward Soltesz, MD, discuss ongoing clinical trials and the ne...

Siva Raja, MD, PhD, provides an update on volumes and outcomes for robotically-assisted thoracic surgery at Cleveland Clinic. https://my.clevelandclinic.org/staff/17512-siva-raja...

For patients with heart failure, a left ventricular assist devices (LVAD) can help the body meet its circulatory needs. Pavan Bhat, MD, and Michael Tong, MD, discuss LVAD as a bridge between medical therapy and a heart transplant, or as a desti...

Daniel Raymond, MD, provides an update on volumes and outcomes for the pulmonary and esophageal surgery programs at Cleveland Clinic. Learn more about the Department of Thoracic Surgery.

Kenneth McCurry, MD, provides an update on lung transplant volumes and outcomes for the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic.View the case study and patient story Dr. McCurry shared.Learn more ab...

The OPTION clinical trial compared left atrial appendage closure to continued oral anticoagulation in patients at risk of stroke after undergoing atrial fibrillation (AFib) ablation. Oussama Wazni, MD and Mohamed Kanj, MD discuss the findings o...

Shinya Unai, MD, provides an update on reoperation volumes and outcomes for the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic.Learn more about the Department of Thoracic and Cardiovascular Surgery.

Marc Gillinov, MD, provides an update on volumes and outcomes for the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic.Learn more about the Department of Thoracic and Cardiovascular Surgery.Looking to refer ...

Luke Laffin, MD, shares the findings from a late breaker he presented at ACC 2025. Lorundrostat is an investigational drug found to significantly lower 24-hour blood pressure among patients with uncontrolled and resistant hypertension. ...

Steven Nissen, MD, shares the findings from a late breaker he presented at ACC 2025.  Lepodisiran is a small interfering RNA that targets lipoprotein(a) levels, lowering a patient's risk for atherosclerosis and aortic stenosis.

Patrick Vargo, MD provides an update on surgery volumes and outcomes from the Aorta Center. Learn more about the Aorta Center. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri....

Faisal Bakaeen, MD provides an update on the state of coronary artery surgery. Learn more about the Coronary Artery Bypass Surgery Center.

Lars Svensson, MD, PhD, Chief of Cleveland Clinic's Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, and Marc Gillinov, MD, Chair of Thoracic and Cardiovascular Surgery, continue their discussion with a detailed overview ...

Join Lars Svensson, MD, PhD, Chief of Cleveland Clinic's Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute, and Marc Gillinov, MD, Chair of Thoracic and Cardiovascular Surgery, as they discuss the unparalleled expertise a...

Haytham Elgharably, MD, discusses new trends and contemporary data from studies on the management of endocarditis. Learn more about the Endocarditis Center. Looking to refer a patient? Please reach out to our Physician...

Robotically assisted heart surgery provides an alternative to a sternotomy that offers many benefits to the patient. Marc Gillinov, MD, and Tarek Malas, MD, discuss these benefits and considerations for a successful outcome.Looking to r...

Amar Krishnaswamy, MD, provides an update on Cleveland Clinic's Section of Interventional Cardiology.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET), toll-free 800.223.2273, ...