Phase Space Invaders (ψ)
With the convergence of data, computing power, and new methods, computational biology is at its most exciting moment. At PSI, we're asking the leading researchers in the field to discover where we're headed for, and which exciting pathways will take us there. Whether you're just thinking of starting your research career or have been computing stuff for decades, come and join the conversation!
Podcasting since 2024 • 33 episodes
Phase Space Invaders (ψ)
Latest Episodes
Episode 29 - Jérôme Hénin: Free energy methods, building useful software, and human learning from biomolecular systems
Jerome starts our conversation by reviewing the history of the ABF method and its advantages compared to the main competitors, and connects it to the development of COLVARS, historically very parallel to how the development of the Plumed tool s...
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Season 4
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Episode 29
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46:01
Episode 28 - Yuji Sugita: Replica exchange, software for massive simulations, and importance of long-distance collaborations
In Episode 28, Yuji Sugita shares the story of how he developed temperature replica exchange in the lab of Yuko Okamoto, connecting to his early experience from working with Nobuhiro Go, the father of Go models. We then talk about the process o...
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Season 4
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Episode 28
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38:54
Episode 27 - Kresten Lindorff-Larsen: Refining force fields, the science of intrinsically disordered proteins, and writing better grant proposals
In episode 27, Kresten starts by explaining his path from a wet lab biochemist to a computational biophysicist, a story full of open-ended explorations and helpful mentors. He gives us some background on how both the legacy and latest models de...
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Season 4
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Episode 27
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49:42
Episode 26 - Pratyush Tiwary: Infusing AI with physics, understanding emergent phenomena, the value of education and thinking
In episode 26, we talk about the origins of Pratyush's passion for statistical mechanics, deeply rooted in his background in material science, and think about how we can promote a profound understanding of statmech theory among people working i...
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Season 4
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Episode 26
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44:16
Episode 25 - Ivet Bahar: Elastic network models, targeting hinges for drug discovery, persistence and alertness
In episode 25, Ivet and me start with a general overview of the elastic network theory and its applications to biology, as well as its strengths and limitations. Ivet then tells us about the specific takeaways from the different lines of her re...
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Season 4
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Episode 25
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39:32