Lab to Market Leadership with Chris Reichhelm

The Hard Thing about Hard Tech – Greg Smithies on the TRL 4-5 Challenge

Deep Tech Leaders Season 2 Episode 5

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0:00 | 1:11:22

How do you move from novel idea to working prototype in hard tech? And how can you bend the rules of the game to give you a better chance of winning?

Greg Smithies is a finance and operations leader who has worked with some of the world's most ambitious companies. He led finance and operations at Elon Musk's Neuralink and The Boring Company. He's also been an investor with Battery Ventures, BMW iVentures and Fifth Wall. He's helped raise over $2bn for startups, and over $950m for funds.

This episode focusses on TRL 4-5 – the prototype stage where many Deep Tech companies stall.

Greg shares how companies like Twelve (e-SAF / carbon transformation) signed a 14-year offtake agreement with British Airways parent company (IAG) while they were still at TRL 4.

You'll learn:

- Why storytelling starts earlier than most founders think

- The three types of hard tech – and why each needs a different capital strategy

- How Neuralink built teams before the company formally existed

- Why off-the-shelf components can be a major advantage

- The biggest hiring mistake – hiring industry insiders too early

Greg outlines three types of hard tech: fundamental new science (Neuralink), re-engineered systems (Boring Company), and economies of scale (solar, batteries, electrolysers). Each faces a different lab-to-market journey.

Essential listening for anyone navigating TRL 4-6

Chapter Notes:

00:00 Runway Experiments Milestones

01:13 Podcast Mission And Stages

03:12 Meet Greg Smithies

05:22 Operator Vs Investor Tradeoffs

08:06 Storytelling And North Star

11:52 Prototype Stage Communication

13:08 Vision First Neuralink Example

15:22 Building Diverse Technical Teams

18:19 Elon Speed And Timelines

22:51 Three Deep Tech Company Types

27:47 Capital Tools For Each Bucket

33:26 Selling Offtakes Early

36:25 Investor Evidence Vs Story

38:05 Defining Best Bets

38:55 Milestones for Next Round

41:23 Runway Experiments Tradeoffs

42:45 Showmanship and Tangibility

45:29 Hard Tech CEO Duality

49:35 TRL1 vs TRL2 Shift

55:14 TRL as Iterative Loop

57:00 Finding the Real Buyer

01:01:24 Who Should Sell It

01:03:39 When to Replace the CEO

01:06:38 Avoiding Industry Insider Trap

01:10:02 Closing Thoughts

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