The Synapse Critical Care & Emergency Medicine Podcast

The Synapse Season 2 Episode 93 - Winters Formula Pearls and Pitfalls

Season 2 Episode 93

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How can we determine where a patient with metabolic acidosis *should* be compensating in regard to expected PaCO2? Enter Winters Formula. In this episode we will talk about how it was derived, its strengths and weaknesses, how to use it, and more. You may be surprised by when and how it was derived, and how long we went without any extra evidence to support it.


Predicted PaCO2 = 1.5 x [HCO2] + 8    (+/- 2)