It's Not in Your Head
Welcome to It's Not in Your Head Podcast, with Dan and Juz. Dr. Dan is a Sports Physician and Justine a Pain Coach and patient. We have come together to find ways to manage complex pain better for both patients and providers. New episodes will come out bi-weekly on all major platforms.
It's Not in Your Head
30 Understanding Hypermobile Ehlers-Danlos Syndrome (hEDS): Symptoms, Diagnosis, & Common Connections
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This episode uses hypermobile Ehlers-Danlos Syndrome (hEDS) as a clinical example of how a metabolic driver can fuel central sensitization. Dr. Bates shares patterns he sees in practice, covering how hEDS should be diagnosed, what markers to look for, and how it connects to CRPS and other sensitization presentations. The discussion includes the role of genetic predisposition, why certain medications should be avoided, the importance of protein intake, and practical management strategies — all delivered with both clinical depth and accessibility so you can make more sense of a complex and commonly misunderstood diagnosis.
Resources:
www.iniyh.com/episodes/ep-30-making-sense-of-heds
Timestamps:
00:00 Introduction to the Podcast
01:00 Diving into Central Sensitization and hEDS
02:25 Understanding EDS Types
03:39 Dan's Journey with Hypermobile EDS Patients
04:50 Identifying Patterns in Complex Patients
05:25 Exploring the Underlying Disease Process
08:39 Mechanisms Behind Hypermobile EDS
09:52 The Role of Protein Metabolism in EDS
11:13 MMPs and Their Impact
18:42 Inflammatory Responses and Immune System Involvement
26:22 Genetic Predispositions and External Triggers
31:13 Understanding Protein Requirements
32:38 Strategies for Increasing Protein Intake
36:20 Choosing the Right Protein Sources
40:47 Long COVID and Hypermobility
46:17 Preventing Disease Progression
54:42 Final Thoughts and Future Directions