Biohacking Eve - Health Optimisation for Women

#6: Decoding Folate’s Role: Enej Kuscer Explores Methylation and Pregnancy Health

Judith Mueller

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Understanding Folic Acid and Personalised Health Optimisation with Judith Mueller and Dr Enej Kuscer

In this episode of Biohacking Eve: Health Optimisation for Women, Judith Mueller and Dr Enej Kuscer delve into the importance of folic acid (vitamin B9) during pregnancy, emphasising its role in DNA and RNA synthesis. They explore the critical enzyme MTHFR, which affects folate conversion, and why methyl folate might be a better supplement choice for expectant mothers.

They discuss how genetic differences impact nutrient absorption, the differences between male and female health needs, particularly during reproductive years, and emphasise the importance of personalised health strategies for optimal wellbeing. Dr Kuscer also provides insights into genetic variations affecting vitamins such as vitamin E and vitamin D. He explains how even identical twins can develop very different biologies over time due to lifestyle choices, despite having the same genetic makeup. Additionally, they explore The NU’s digital twin platform, which leverages multi-omics data to provide highly personalised health insights and predictive health strategies.


Links:

www.TheNU.com 


Episode breakdown:

  • 00:00 The Importance of Folic Acid in Pregnancy
  • 02:44 Introduction to Biohacking Eve and Guest Speaker
  • 03:10 Understanding The NU Digital Twin Platform
  • 03:42 User Experience and Benefits of The NU
  • 08:13 Health Optimisation Differences Between Men and Women
  • 20:37 Genetic Variations and Their Impact on Health
  • 28:16 Personalised Supplementation and Health Strategies
  • 34:55 Call to Action: Owning Your Biology
  • 37:23 Conclusion and Final Thoughts

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Website: www.BiohackingEve.com

Judith Mueller

there was one really interesting example that you and I have touched on previously regarding folic acid in pregnancy

Enej Kuscer

Folate this is the vitamin B9, right? This is the essential precursor in this very I'll just say complex pathway of methylation. But even more importantly, it's the essential substrate when you're building new building blocks of life, which is the DNA and RNA synthesis, right? When you think about what's happening with females when they're pregnant, of course, they're creating new life. There's a huge amount of fresh DNA being synthesized, Which just means it sucks all the folate out of your body, Which is why women need to get an extra supplementation of this vitamin B9, the folate, on this conversion of the folic acid through your methylation pathway, there is a few very, critical enzymes of which one is really absolutely the bottleneck. This one is called MTHFR, And, basically, it converts one let's say part of the folate story to another. And in a lot of people, this enzyme has a significantly lower activity. Which means that your folate is not being activated is not being converted. Basically, it's being discarded from the system now for us adults that creates a lot of minor annoyances, right? But then when you're thinking about the pregnancy, it becomes even more critical, right? Because there you're actually providing the substrate of New life, right? Of new DNA synthesis. So again when, you're thinking about how do I support my growing fetus, my baby in the best possible way, right? there is a folate you can buy a regular vitamin B9. or a methyl folate, Which is an activated form of this vitamin B9 and both can be bought in a regular pharmacy. One is maybe a little bit more expensive, but not much, But it does bypass this one critical step, right? So it would be the same recommendation. Yes, you do need a folate precursor for your healthy Pregnancy, but maybe you should just consider which one you're taking, right? the entire pathway the, kind of the deficiencies on this pathway, it's, Upwards of 20 percent in terms of the prevalence in the human population. So, being aware of these, let's say, methylation stories is really quite important.

Judith Mueller

Welcome back to Biohacking Eve Health Optimization for Women with Judith Mueller, where we shine a light on everything that will help you reach your best self as a woman, as unique and individual as you can be. Live long and prosper, my friend. Hello everyone. Today I'm joined by Dr. Enej Kuscer, who's the CEO of The NU. The NU is a digital twin platform that integrates a comprehensive 360 degree multi omics analysis, which basically means that The NU is leveraging genome, epigenome, blood, microbiome, wearables, and other health data inputs to deliver highly personalized health insights and precision optimization health strategies. Enej, love it to meet you.

Enej Kuscer

everyone. Bye bye.

Judith Mueller

Fantastic. Could you tell us a little bit about how this system works in practice? What do I actually see and have to do from a consumer point of view?

Enej Kuscer

Yeah, so it's really as easy as possible. So a, it's an open platform where people can upload their data. If they already have them, people can go online and purchase the best kits from us directly, or they can use third party testing, et cetera. New is really all about that. One place where you can connect all of your data, integrate that and get really amazing insights out of what your biology is doing, how you can optimize that health and so on, interact with your, let's say, digital twin, right? In terms of, let's say, 2 cases of a user experience, 1 is somebody that is completely new to the field, has never done any of that stuff, has been listening about. Health span and longevity and optimization or whatever our personalized health, but maybe never ventured into it themselves. So they can go online, just go to our website find the shop. They can buy the whole either from a very basic testing. Again, if they just want to with their toes first, or they want to go all in and see the as you mentioned, the genome, the epigenome, the gut biome, the blood biomarkers, and so on, right? You can get, you can buy the test kits, you get it delivered to your home, you do your saliva sampling a stool sampling, and then you, do a, blood analysis at the local lab. And then all of that data gets integrated into the platform, into your profile, into your digital twin. And then you see the outcomes, the recommendations, your biological age clocks and so on. On the other hand side, like I said, also if you just want to wet your toes, you can just maybe start very simply just maybe some basic genetic tests and some very minor like an annual health checkup, blood profile. And you can already start getting a lot of insights from that. But then you the more you get comfortable with your story, the more you build out, Oh, I want to know more about my gut biome and how does that affect my health or where's my epigenetic story evolving, et cetera. On the other hand side persona number two, Would be somebody that is really living it, right? So they've been doing that for years. They're very much aware of they, may even call themselves the biohackers or whatever, right? So they've done maybe at least a 23andMe genome and a few blood tests in the past, and maybe a gut biome or not. They have the data, right? So if they've been using service providers that allow them to get access to raw data, they will be able to download that and just upload into The NU platform. So again, with us, you really are the owner of your data. We are the custodian. It's, highly encrypted, highly secure, and so on, but you are the master of your data, right? So if you bring your own stuff, just upload it and it gets processed and it gets incorporated in kind of your historical biological profile. The problem. Out there is that many of those companies do not give you access to raw data. So in that case if you've done some of these types of, tests, you may only get the very simplified PDF report that will say eat more broccoli and less spinach. You, you maybe don't even know why, but you will not actually get to see why what are the kind of biomarkers behind, et cetera. So the raw data is important.

Judith Mueller

And actually speaking of raw data obviously I would have that from a consumer point of view, but how could I integrate working with my clinicians on that, my healthcare providers, if I wanted to

Enej Kuscer

Yeah, so this is really where NU shines where the current, let's say, primary focus of The NU activities is aimed at is really working with practitioners. And of course, with the end consumers via the practitioners, because there are still so many. Very let's say complex things to understand about your health journey, your health optimization. It's always good to work with a professional, right? So whether that's a dietitian or a nutritionist or a longevity medicine practitioner, et cetera. the data flow is then really seamless the clinician or the practitioner works with their clients or their patients. They basically oversee the sampling and so on. And then basically they are also the ones that can help guide the client through their digital twin experience and the kind of prioritization of the challenges, et cetera, et cetera.

Judith Mueller

super let's get to the nitty gritty, given that we're women's podcasts, are the sort of surprising insights that you've seen around that topic?

Enej Kuscer

There's many areas that are very important for us to differentiate between men's health and women's health, right? So while, when we're thinking about health optimization and longevity, there's I don't know if we could call it like an 80 20 rule or I don't know the statistics on that, or probably it will be hard to gauge, but. Yes, for sure. Eat well take care of your nutrition and diet exercise maybe do an occasional fast, pay attention to your sleep all these things. Yes. They're important, right? They're important for everyone. Then you come to your, okay. It's already started to become a little bit more specific when you're thinking gut health and this and so on, but when you're looking at the difference between male and female, it really starts becoming very, different in terms of the reproductive health, the hormonal journey of us from teenage years onwards, as we evolve as we get older. Very different types of beings men produce their sperm for their entire lives and they are fertile basically until more or less their nineties or even basically until the end, whereas female they're born with a finite set of eggs that's defined basically already with, during the I don't, I forget which week during the pregnancy, et cetera, and that's it. And it's a very, fast decline, rapid decline in terms of the reproductive health. And we are actually, interestingly, one of the few species out there that even have this phenomenon called called menopause, right? So there's only a few other whales and probably some, other exotic species, but like most primates don't have menopause. And, also going through the monthly cycle of, the whole kind of play or concerto of your hormonal balance and, the way the body each time is preparing whether it may get pregnant or not, et cetera. So there really is a lot of aspects of that we were thinking about how to maintain your reproductive health, which, may drag down a lot of other health related issues if it declines too rapidly. But then on top of that, we add the pregnancy, right? Because there again, the male is the donor of the sperm. Easy done, right? But for female, you're then taking care of two living beings, right? Which they need to now all of a sudden you have the father's genetics in there as well, which has different metabolic pathways, different hormonal pathways, and so on. So all of a sudden, It's not just your own, let's say, metabolism optimization, but you need to think what is my ideal support in terms of the nutrition, the minerals and so on and so forth that the fetus requires. So it really becomes way more complex. Yeah, it's a very good question. And they're using a. Systemic approach such as NU or probably there are others, but really trying to understand your body holistically, right? You will be able to address a lot of these issues much more with the knowledge of What is going on within the system rather than seeing that something is not working and then trying basically all sorts of solutions, just whether something else might work. We've seen, so we've seen quite a few women that came onto the platform that had for many years trouble with for example, fertility, getting pregnant and so on. And of course the platform will identify many of the key features inflammation, gut biome dysbiosis, right? It will be stress levels hormonal imbalances and so on, right? And when you put all of those things, again, rebalance provide that reset of the system with a supplementation with dietary changes and so on. Many of these within months, are able to You know, conceive that they haven't been able before. And they've been taking all sorts of hormonal therapies and this and that. Or even when you then think about longevity. And again, this has not just been with our platform. I saw that as n equals one report studies from, let's say, lady bio hackers out there that this is not an uncommon feature when you think about menopause. Women who did not want to accept that they declined too soon and they started to really look at all sorts of biomarkers. How can we improve this and that? We've seen that in our case, that years into the menopause, women have been able to reverse their biological age and actually have Experiencing the period and all the kind of premenopausal stories again, right? So you can really do a lot about keeping your cells and your body or biology functioning healthier and younger for much longer. But again, it takes that systemic approach to not just going after one, let's say pathology that you're seeing or observing, but actually trying to understand why that is happening and which are the, all the contributing factors, right?

Judith Mueller

And I think there was one really interesting example that you and I have touched on previously regarding folic acid in pregnancy. you want to

Enej Kuscer

Yeah. Yeah, for sure. Folate is the essential, this is the vitamin B9, right? This is the essential precursor in this very I'll just say complex pathway of methylation. So C1 donor, right? This is a one carbon unit, right? Which is important for synthesis of a number of hormones like serotonin, dopamine, and so on. So you're but at the same time as a methylation let's say story, it's about regulation of activities of enzymatic of protein activities and so on. But even more importantly, again, as a carbon one donor, it's the essential substrate when you're building new building blocks of life, which is the DNA and RNA synthesis, right? When you think about what's happening with females when they're pregnant, of course, they're creating new life. There's a huge amount of fresh DNA being synthesized, right? Which just means it sucks all the folate out of your body, right? Which is why women need to get an extra supplementation of this vitamin B9, the folate, to support these methylation pathways and the carbon one synthesis, et cetera, et cetera. Now, with this pathway, there is a very interesting And to me, evolutionary, not very clear phenomenon of these MTHFR deficiency, because very often we have there are enzymes in our metabolic pathways that are either over expressed or under expressed that we have as a species accumulated through time. And we have these things called single nucleotide polymorphisms, which means this is how we differ from one one to another. On single nucleotide changes, and usually this meant evolutionary that at some point in the history for some subpopulation, a higher activity of an enzyme or a lower activity of enzyme was beneficial. And so that mutation took place and then took hold and it's still prevalent today. And very often, these are not necessarily fully detrimental, just a certain type of interesting advantage in certain type of environment. But with MTHFR. I'm not entirely sure where the kind of evolutionary story of this gene is, but on this conversion of the folic acid through your methylation pathway, there is a few very, critical enzymes of which one is really absolutely the bottleneck. But there are another four or five that are evolved. This one is called MTHFR, and it's called hydro reductase. And, basically, it converts one let's say part of the folate story to another. So it basically it's, a step in between. And in a lot of people, this enzyme is has a lower activity, significantly lower activity. Which means that your folate is not being activated is not being converted. Basically, it's being discarded from the system now for us adults that creates a lot of minor annoyances, right? So if we are MTHFR deficient, if we have a lower activity of this enzyme, it means that your. Neurotransmitter, your hormonal pathways and so on are more poorly supported, for example, right? Which means you have, let's say, a smaller buffer zone of what you can handle in terms of serotonin, dopamine all this, and then which very often leads in terms of the kind of consequence to. Mood swings, moodiness, anxiety, depression, all these kind of things. And then people would often say that's just who I am. The reality is you may just have a lower activity of these enzyme, which means that if you supplement correctly and bypass the defects of these enzymes you, may quite likely let's say rebalance your more flow state of your mind, of your cognition. But then when you're thinking about the pregnancy, it becomes even more critical, right? Because there you're actually providing the substrate of New life, right? Of new DNA synthesis. So again when, you're thinking about how do I support my growing fetus, my baby in the best possible way, right? For example, when we spoke about this gene there is a folate you can buy a regular vitamin B9. or a methyl folate, right? Which is an activated form of this vitamin B9 and the same, and both can be bought in a regular pharmacy. One is maybe a little bit more expensive, but not much, right? But it does bypass this one critical step, right? So it would be the same recommendation. Yes, you do need a folate precursor for your healthy Pregnancy, but maybe you should just consider which one you're taking, right? So that's one interesting example that it's just one out of many to think in terms of how do I really provide that optimal nutrition, optimal kind of mineral, vitamin and other support, et cetera, et cetera, for my own body as well as for my potentially my

Judith Mueller

And the thing fetus. correctly, it's about 20 percent of the population that has this deficiency. So especially as

Enej Kuscer

yeah,

Judith Mueller

one hell of a risk to take to not know That.

Enej Kuscer

It's really hard. It's not, I would not say that the MTHFR, particularly the gene has a homozygous minor prevalence of 20%, but the entire pathway the, kind of the deficiencies on this pathway, I think it's, Upwards of 20 percent in terms of the prevalence in the human population. So, being aware of these, let's say, methylation stories is really quite important.

Judith Mueller

And sticking with parenting, I find it quite interesting when you say if a couple has several kids, for example when you told what the genetic similarities, but also differences between the kids, which are siblings, which have the same set of parents, the same set of input theoretically, but not necessarily in practice. That's also a very interesting story.

Enej Kuscer

Absolutely. And again we're talking a very similar analogy, right? So here, so you have in the same story, as I said earlier you have enzymes that are more active, you have enzymes that are less active, you have pathways that they're underexpressed, etc. And you always get two copies of a gene from your parents, one from each, right? And then the genes can be either dominant, they if there's one copy of something, it just takes control or recessive, which means that it's usually silence So it needs to have two copies, right? In order for it to be able to voice its opinion, right? Or you have an equal strength that each one plays contributes to a role. And so first of all, you need to know what type of genes those are, right? So are they the dominant player, the recessive players or, and then then you look at how these stories combine. So again let's say mother and father might have in certain number of genes in one area of, let's say related to your, hormones or mood and stress, anxiety, whatever, which is quite often in terms of kids. And you may have one copy of each here and here, but how they recombine this, the child can get two of the dominant versions, two of the recessive versions or one from each, right? So while you have kids, they can have completely different stories, how the genetics, you know, even in. All of us who are healthy people, right? So we're not talking here about any kind of genetic diseases and so on. We're talking about different, let's say evolutionary stories that came along through this polymorphisms, how they eventually combine in us that create this kind of unique, right? And it's interesting, because a lot of these then also plays a very interesting role in your, let's say, for example, your gut, your epithelial cells, right? Because while they we talk about a lot about gut microbial health and so on and so forth. And people say diet, right? So high fiber and this and fermented foods, et cetera, et cetera. But there is this also very huge Because it's almost like a symbiotic relationship, right? So there is a huge influence between the host and the bacteria in there. So the type of the cells, the type of mucus, the type of adhesive proteins and so on that are on your own cells. Will create a hosting environment for the type of bacteria that like to flourish there. So even within the same family who tends to eat the same foods lives in the same household, you will actually have some aspects of your gut biome that are amazingly equal, right? Similar, but then there will be aspects of your gut biome that are very unique, right? And it's going to be very interesting stories. All these let's say. Journeys evolve

Judith Mueller

Are there any particular genes where you would put a lot of attention on in terms of mutations for children in particular?

Enej Kuscer

what we discussed earlier, MTHFR is definitely one of them, right? For example, this really is a very prevalent and very important story that impacts your hormonal balance, your overall kind of development, et cetera. Other than that, I would say there's a lot of aspects that relate to your. Let's say nutrition your nutritional uptake. For example, when we think about when you go through this massive period of changes in your body composition and structure the bone and so on. You really want to know how can you handle, for example, your, vitamin D pathways, et cetera. So again, there is a number of, genes that are either how responsive you are to synthesizing that from the exposure to the sun from converting that into your, in the liver to an active form uptake into the cell and gene response, because this is actually a regulator, et cetera, et cetera. So again, the same as in MTHFR, there are a number of genes involved. And on top of that, there's a number of bacteria in your gut that synthesize. Or not the vitamin D, right? For example when, you think about the, kind of growth of your body, the immune system, the bone, the muscle, that even the neuronal developments a lot of these kind of vitamin, mineral pathways, the nutritional uptakes, or the gut uptake, et cetera, is really important to know where, whether you're well supported. Or whether a minor amount of supplementation might be beneficial. The same goes with kind of B vitamin pathways, the K vitamin and so on. Which again is, very important for growth. So I think here we are more focused on the nutritional and metabolic support and hormonal support rather than maybe the more longevity aspects of again, If we really want to be very very, detailed or very fast, but then then we face the other problem that we get to zealous about trying to control just about everything, right? Because again, I think that children can metabolize a lot of things still with a much greater degree of buffering than. We can write, but we were talking about evolutionary genes and even in that front some people are just way more capable of processing certain types of grain than others, certain types of fats than others and so on. For some kids, it might really be a very good idea to for anyone, it's a good idea to avoid too much sweet, et cetera. But but. Some kids are grown or, I don't know, nurtured on cereals for their entire young lives. And while there's nothing inherently wrong with cereals, especially if they're whole grain and if there's not too much sugar in there for some genetics, cereal is really not a good choice, right? And so if you know that, You may avoid causing your child having a lot of unnecessary inflammation and that inflammation can drive cardiovascular metabolic disease, even at the quite a young early age. And again, I wouldn't say ban cereal because cereal is amazing stuff. We exploded as as, a society when we invented growing cereals or growing grain but for some people that really isn't the best choice.

Judith Mueller

so the final point personalized supplementation, what's the easiest way to go about that?

Enej Kuscer

Yeah. So again, it touches the same, aspects as we spoke. We spoke with all these examples. It's all about 1st, knowing who you are. So I'll use my own example. For example, I mentioned vitamin D earlier, right? And the number of genes and disclosure, I'm the worst genetic inheritance that you can imagine on the vitamin D story, right? So I've got really poor let's say, ability to synthesize from sun. I have a very poor conversion in my liver, so activation. Then I have very poor intake or uptake into the cell. Very poor vitamin D receptors, very poor transcription. So in terms of gene activation, et cetera. So I'm on the lower 20th percentile of my genetic code, right? But then I look at my circulating vitamin D in my blood is actually not bad, right? It's not optimal, but it's not bad. And as an entrepreneur, I don't really go out to the sun that much. Unfortunately, I should go out more often I, I try to at least five, 10 minutes a day, but it's not enough. So what happened there was it seems because I pay attention to my diet. And my overall well being and exercise and so on and so forth. I've been able to cultivate gut bacteria that are amazing, super producers of vitamin D, right? I'm providing as a host, the right environment that I give them something. They give me something right. Then it seems like this is almost an again, a a story that evolves through time when you can feel the what, your body needs, right? Again, if I just looked at my genome so again, that, that brings us to the problem of today's industry is people do very much a silenced approach, like they do just genetic testing with one company and then say Oh, this is what my genes are telling me this is what I should be doing. And then they start overdosing some stuff, right? That can be quite dangerous, right? You take identical twins. One is a couch potato. One is an athlete. One leaves inside and keep some being under stress, et cetera. The other one is climbing mountains, eating healthy foods. They will have completely different biologies, right? In 20, 30 years time. Genetics is only what your cells can do, right? But you have to actually take a holistic view at what is going, what is really going on, right? So I still supplement with vitamin D to bring it from the okay ish to the optimal, right? But if I just went by my genetics, I would start overdosing and that wouldn't be too healthy, right? So So this is where you really then crunch the data. So when you think about personalized supplementation then you have to think about again, multiple aspects, which is what you can see in our platform, right? How much evidence is there for certain things? So with the nutritional deficiency. There's plenty of evidence. For example, if you're deficient in certain types of minerals and vitamins and so on all the kind of correlations with the bad health outcomes, et cetera, are there there are certain vitamin supplements and so on that are also quite strongly now starting to be correlated with more of the longevity aspects of it, at least, or at least healthier aging, right? For many others however, we may either have anecdotal evidence or thousands of years of ayurvedic tradition and so on. Is ashwagandha good for you hard to say again, yes, we can say, because actually there's a lot of science growing in that field. But all I'm saying is you have to first take into account how much, how strong is the evidence. What's my data? And so when you look at your data, then you really look at your metabolic pathways, your genetics, your gut biome, your current blood biomarkers, your epigenetic aging processes. And then you start addressing them in terms of the kidney. Do I want to support my mitochondrial biogenesis, which are the right pgc, one alpha activators, and so on. Or they want to really just keep it low and make sure that I'm not deficient. Of course, you have to be mindful whether there is a systemic inflammation going on. You certainly want to take care of that. What's your glucose metabolism, lipid metabolism and so on. So again, layers, right? When do you start going into senolytics? That's the question. How much, is there a personalization data on quercetin and fisetin and so on? Not much, but is there a solid data that Quercetin might be a good thing in terms of kind of longevity strategy? I think so, right? what you want to know is it safe for me? Because you can take the simplest example. Again, I'll use something that probably most people are familiar with I don't know, a vitamin E, right? A simple antioxidant, right? And we've shown even our group has recently published a paper Vitamin E for certain type of, let's say genetics, which is not a gen like we discussed earlier. It's not a genetic disease, it's a genetic uniqueness of one population versus the other population. So for a certain type of genetics, vitamin E is like fuel to the fire, to any type of cancer. So it'll actually increase your likelihood of catching cancer within the next decade or so, right? Versus for the other type of population vitamin E is really. Putting out the fire, right? So it's helping yourselves to defend better. And it's actually reducing your likelihood of catching cancer and so on. So even the simplest vitamin like that can actually be causing more harm than good or vice versa. And for others, it's quite, neutral and irrelevant. So you're just wasting money.

Judith Mueller

Interesting. Super interesting. And I was loving to have you on. Is there anything any sort of any single point that you wish that your, customers, your fellow research, your fellow entrepreneurs would really know about and take to heart that you think would absolutely move the needle in your field?

Enej Kuscer

It's just a call to action, The time is now that people start owning their biology, that people really get on this train of knowing their data, monitoring their data starting to build their trend lines and seeing how they can start optimizing their health. The future of precision and preventative and longevity medicine is so insanely exciting ahead of us. With all the stuff that is even in the lab today, in terms of let me not even start getting into that because people might think it's science fiction, but it's really insanely exciting. And we have this one vehicle in life that we that we can rely on and that the more we maintain it in, in in great shape, the more we can collect the data, know, and be in the driver's seat in the op know the user, the operating manual, right? The more likely we're going to be able to see that exciting future. I would not go with a guesstimate. On your own body, right? Know it, own it, right? That's how you start. And this is why we developed The NU as a platform. Is really, that's your that's your digital twin. That's your data where you start you upload your historical record. You start with systems approach now. Then you monitor, retest, if you want every quarter, if you want every year even if you do every two year, it doesn't matter. Because what you want to do is. First, really know, how can I start optimizing and then monitoring preventively building that, no knowledge of my body and kind of being able to take action before things become a problematic a pathology. So anyway,

Judith Mueller

Sounds

Enej Kuscer

that's it.

Judith Mueller

So where can people find you?

Enej Kuscer

It's a very simple, it's just www The NU. com. Yeah. So it's the new means. New actually means now in Dutch, right? So it's a call to action. So while you can play, it's a new live, new you, new era, but new means now which is really the case, right? So very often people take new year's resolutions and then say, Oh, or they say, yeah, I know I should do something this project at work and my kids and this I'll do it next year, right? There's always some reason to not, go for it. But I think, I really think the time is now.

Judith Mueller

Fantastic. Thank you very much. Thank you for joining me on this transformative journey. Your presence in this community is truly valued. Now, you may not realize it, but your words hold immense power. They have the ability to reach others who may benefit greatly from the wisdom shared here. If you found value in what you heard, I kindly ask you to take a moment to subscribe to Biohacking Eve, leave a glowing review on your preferred podcast platform, and share Biohacking Eve with your friends and family. Your support helps spread the message of health optimization for women far and wide. Lastly, I want to express my gratitude to you for investing in yourself. By prioritizing your well being, you serve as an inspiration to others. I'm eagerly looking forward to bringing you many more exciting episodes, and thank you for being a Biohacker. Right. The part of our community live long and prosper, my friend. The Biohacking Eve Health Optimization for Women podcast is for general informational purposes only, and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the given of medical advice and no doctor patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be substituted for professional medical advice, diagnosis, or treatment. Users should not disregard or delay obtaining medical advice for any medical condition they may have and should seek the assistance of the healthcare professionals for any such conditions. In addition, the information on this podcast does not constitute investment or financial advice.

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