THE HUMAN CONDITION

CRISPR-Cas9

ADG Season 2 Episode 11

By Dr. Alfred Granite

Dr. Granite's newsletter explores the CRISPR-Cas9 technology, tracing its accidental discovery in bacteria to its potential for revolutionizing healthcare. It emphasizes the rigorous scientific process behind CRISPR's development, contrasting it with politically motivated endeavors. The newsletter highlights the FDA's approval of Casgevy and Lyfgenia, the first CRISPR-based treatments for sickle cell disease, while also acknowledging challenges like chemotherapy requirements and high costs. Dr. Granite points to resources that help explain the complex technology, emphasizing its role in future genetic medicine, using videos and podcasts for easier understanding. The article also explores LUCA, the Last Universal Common Ancestor, as a way to highlight genetics and the fundamental building blocks of life and the possibilities for AI to discover new uses.

Newsletter: https://the-human-condition.beehiiv.com