Master Stress with Dr. S

Longevity Beyond Biohacking: Dr. Jeff Gladden on Exponential Aging, Purpose, and Health Optimization - Part 1

Safia Debar Episode 81

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0:00 | 29:55

Dr. S introduces a podcast series on longevity and interviews Dr. Jeffrey Gladden, a cardiologist-turned-longevity physician and founder of Gladden Longevity in Dallas. Gladden describes how, despite being told his labs were “normal for his age,” he experienced weight gain, fatigue, anxiety, brain fog, and depression in his 50s and felt conventional medicine offered only sick care. After a two-and-a-half-year functional and integrative medicine deep dive, he identified subclinical hypothyroidism, genetic thyroid conversion issues, hormonal depletion, and neurotransmitter challenges, and found targeted therapies plus meditation helped him recover. He explains aging is biologically exponential and outlines his five-circle systems approach—life energy (psychospiritual), longevity (hallmarks of aging), health, performance, and environments—guided by questions like “How good can I be?” and “How do we live young for a lifetime?”

00:00 Longevity Everywhere
01:58 Meet Dr Jeff Gladden
04:07 Cardiology Wake Up Call
06:37 When Aging Accelerates
08:05 Functional Medicine Breakthrough
12:00 Leaving Conventional Medicine
12:51 Courage Purpose Identity
17:16 Spiritual Roots And Psychedelics
20:27 Love Creates Joy
22:48 Five Circles Longevity System
27:28 How Good Can I Be
28:23 Part Two Teaser

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