The Glucose Never Lies® Podcast
Host John Pemberton — diabetes educator, researcher, and dad living with type 1 since 2008 — explores how to think clearly about type 1 diabetes in the real world.
EACH episode translates current evidence and expert practice into decisions you can use: CGM accuracy and interpretation, getting more from pumps and automated insulin delivery, movement as a glucose tool, nutrition that protects performance and enjoyment, sleep, travel, parties, and sport.
Guests include leading clinicians, researchers, and people with lived experience. Expect respectful challenge, plain language, and practical take-aways.
Note: Educational only. No therapeutic relationship or personal medical advice.
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The Glucose Never Lies® Podcast
15: C-Peptide - What type of type 1 diabetes do you have?
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Hosted by diabetes dietitian John Pemberton, this show blends science and real-life experience to make managing type 1 diabetes easier, clearer, and more human. Smart insights, practical tips, and honest conversations await.
It's all about C-Peptide and what it means for people living with T1D!
🕒 [00:09] Think all T1D is the same? Think again.
🕒 [02:14] Some people really do have it harder — and “brittle diabetes” might be real.
🕒 [04:37] Enter C-peptide: a marker of how much insulin your body still makes.
🕒 [06:10] Know your number:
• High: >200 pmol/L
• Intermediate: 30–200
• Low: <30
🕒 [09:11] Diagnosed young? You likely have lower C-peptide. John, diagnosed at 27, still has 220 after 10 years.
🕒 [10:20] High C-peptide = better time-in-range, fewer hypos, fewer complications.
🕒 [13:10] Why? More portal insulin + less glucagon = smoother control.
🕒 [14:01] Use your C-peptide to prioritise tech and tailor therapy (GLP-1s, HCL systems, nutrition).
🕒 [17:55] Most of all—be kind to yourself. It’s not weakness. It’s biology.
Key resources
Episode 14: Insulin Resistance and T1D
C-Peptide full article – click here
