17 – GLP-1 in Type 1 Diabetes: beyond weight loss, towards metabolic therapy? Artwork

The Glucose Never Lies® Podcast

Host John Pemberton — diabetes educator, researcher, and dad living with type 1 since 2008 — explores how to think clearly about type 1 diabetes in the real world.

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The Glucose Never Lies® Podcast

17 – GLP-1 in Type 1 Diabetes: beyond weight loss, towards metabolic therapy?

September 12, 2025 • John Pemberton • Episode 17

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Episode 17 — GLP-1 in Type 1 Diabetes: Beyond Weight Loss, Towards Metabolic Therapy

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Guest: Professor Viral Shah, MD

Professor of Medicine & Director of Diabetes Clinical Research, Center for Diabetes and Metabolic Diseases, IU School of Medicine
Author of multiple clinical trials and consensus guidelines on GLP-1 and incretin therapies in type 1 diabetes

In this episode, John Pemberton speaks with Professor Viral Shah, a leading researcher in incretin therapies, about:

The unique challenges of type 1 diabetes (insulin resistance, glucagon, weight gain).
The evidence for GLP-1s in T1D: up to 30% insulin reduction, weight loss, and improved time in range.
Practical guidance for people with type 1 and healthcare professionals: insulin titration, MDI vs pump vs AID, nutrition, and risk–benefit.

Subscribe to The Glucose Never Lies® and receive the Summary PDF with all the key take-home messages and practical implementation strategies.

Go to the Podcast page for all the notes, insights, and further reading & listening.

Related GNL Resources

Overcoming Insulin Resistance in T1D
Eight Caus

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Collaboration: John Pemberton — john@theglucoseneverlies.com

Creatives: Anjanee Kohli — anj@theglucoseneverlies.com

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Disclaimer
This content is for informational purposes only and does not constitute medical advice.