Down For Health

“The Role of Inflammation in Down Syndrome and How to Tame It”

Blake Butler Episode 3

In this enlightening episode, we explore the critical connection between systemic inflammation and health outcomes in individuals with Down syndrome. Emerging research points to chronic inflammation as a contributor to a variety of health challenges, including autoimmune conditions, cognitive decline, and cardiovascular issues.

Join us as we break down:

📚 Key studies highlighting the link between inflammation and Down syndrome

🥗 The role of anti-inflammatory diets like the Mediterranean or plant-forward approaches

🐟 How omega-3 fatty acids can support immune health and reduce inflammation

🧠 Practical tips to support overall wellness through nutrition and lifestyle changes

Whether you're a parent, caregiver, or health advocate, this episode is packed with actionable insights to help you or your loved ones thrive.

🔍 Resources & Links:

Learn more and access helpful resources at: www.downforgreens.co

Sources

  • Huggard, Dean et al. “Increased systemic inflammation in children with Down syndrome.” Cytokine vol. 127 (2020): 154938. doi:10.1016/j.cyto.2019.154938
  • Malle, Louise et al. “Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells.” Nature vol. 615,7951 (2023): 305-314. doi:10.1038/s41586-023-05736-y
  • Mara et al. “Down Syndrome Is a Metabolic Disease: Altered Insulin Signaling Mediates Peripheral and Brain Dysfunctions.” Frontiers in neurosciencevol. 14 670. 8 Jul. 2020, doi:10.3389/fnins.2020.0067
  • Pecoraro, Luca et al. “Lipid Profile, Eating Habit, and Physical Activity in Children with Down Syndrome: A Prospective Study.” Diseases (Basel, Switzerland) vol. 12,4 68. 29 Mar. 2024, doi:10.3390/diseases12040068
  • Joanna, and Dariusz Włodarek. “General Dietary Recommendations for People with Down Syndrome.” Nutrientsvol. 16,16 2656. 11 Aug. 2024, doi:10.3390/nu16162656