Live from Stage 4: MBC News for Us, by Us
Could a cure for breast cancer be closer than you think? Welcome to "Live from Stage 4" — a bold, hopeful podcast where people living with metastatic breast cancer, clinicians, and researchers take center stage. We share real stories, decode the science, and spotlight the ideas and breakthroughs that matter — for patients, caregivers, and anyone who believes progress is possible. This podcast is for us, by us, and all about us.
Episodes
48 episodes
Developing Story: How PCDI Is Changing the Way We Think About Dosing
When Anne Loeser noticed that MBC patients like her were struggling with crushing side effects from cancer drugs prescribed at maximum tolerated dose (MTD), she asked a radical question: Does it have to be this way? That led her to found the Pa...
Symptoms Spotlight: Osteonecrosis of the Jaw (ONJ) with Abigail Johnston and Melanie Sisk
Learn about osteonecrosis of the jaw (ONJ), a rare but serious side effect of bisphosphonates used to treat bone metastases. In this episode, Abigail Johnston is joined by Victoria Goldberg, executive producer of the podcast and fellow ONJ pati...
Developing Story: From CLEOPATRA to Life on Enhertu – HER2+ MBC with Dr. Erika Hamilton & Dr. Sarah Premji
Twenty-five years ago, the diagnosis of HER2+ breast cancer was a death sentence. Two-year survival was roughly 50%. Today, oncologists are using the word "cure" in the metastatic setting.Co-hosts Victoria Goldberg and Abigail Joh...
Say Their Name: Remembering Dr. Jill Tirabassi
This is the first episode of a series we never wanted to make.Jill Tirabassi was a physician in Buffalo, a mother of two little boys, a lifelong athlete, a gardener who was happiest with dirt on her hands, and a member of the Live From S...
Symptoms Spotlight: Chemo-Induced Nausea and Vomiting (CINV) with Abigail Johnston and Melanie Sisk
Chemotherapy-Induced Nausea and Vomiting (CINV): Managing a Common Side EffectNausea and vomiting are common side effects of chemotherapy, but the strategies that work for everyday nausea often fall short. In this episode, Abigail...
Developing Story: What Biomarkers Tell Us with Dr. Neil Vasan
Biomarkers are transforming how we understand and treat breast cancer, but what do they actually mean?In this episode, we break down the three layers of biomarker testing: DNA biomarkers that reveal genetic mutations like BRCA1 an...
Symptoms Spotlight: Ascites with Abigail Johnston and Melanie Sisk
In this Symptoms Spotlight episode, Abigail Johnston and Melanie Sisk are joined by Dr. Jill Tirabassi to talk about ascites, the buildup of fluid in the abdominal cavity that can occur with metastatic breast cancer and liver disease. Dr. Jill ...
Thriving Together 2026: From Silent Voices to Hear My Voice - 20 Years of the LBBC’s MBC Conference
This is a disease no one wants, but you meet the best people."Twenty years ago, about 125 people gathered at a hotel outside Philadelphia for the first-ever conference just for those living with metastatic breast cancer, at a time when t...
On Our Own Terms: A Conversation About Medical Aid in Dying, Dignity, and the Choices We're Afraid to Make
Nobody wants to talk about dying. But what happens when we do?On August 5th, 2025, New York becomes one of only a handful of states where Medical Aid in Dying (MAiD) is now legal. For people living with incurable or terminal illness, thi...
Developing Story: Triple Negative MBC - Hard Truths, Real Hope with Dr Sarah Premji
Triple negative metastatic breast cancer is one of the most complex and rapidly evolving frontiers in oncology, and this episode is your most comprehensive guide to understanding it.Victoria Goldberg sits down with Dr. Sarah Premji, onco...
Symptoms Spotlight: Blood Clots with Abigail Johnston and Melanie Sisk
In this episode of Symptoms Spotlights, hosts Abigail Johnston and Melanie Sisk, a metastatic breast cancer patient and a registered nurse living with MBC, dive deep into one of the most serious yet underdiscussed risks facing cancer patients: ...
Developing Story: Your Cancer's DNA and the Trial Using It to Cure You with Dr. Pedram Razavi
What if metastatic breast cancer didn't have to mean a lifetime of treatment? For a subset of HER2-positive patients, that question is no longer hypothetical.In this episode of Live from Stage 4, hosts Victoria Goldberg and Dr. ...
Symptoms Spotlight: Vaginal Dryness with Abigail Johnston and Melanie Sisk
In this episode of Symptoms Spotlight, hosts Abigail Johnston and Melanie Sisk take an honest and personal look at one of the most common yet least talked about side effects of metastatic breast cancer treatment: vaginal dryness.Both liv...
Developing Story: The Trial That Dares to Say Cure with Dr. Lior Braunstein
We've always been told that metastatic breast cancer can't be cured, only managed. But what if that's no longer the whole story?In this episode of Live from Stage 4, hosts Victoria Goldberg and Dr. Ellen Landsberger sit down wit...
Developing Story: CureWise Goes Live - The AI Platform Built by Cancer Patients, for Cancer Patients
Last time, we had a front row seat to a vision. This time, that vision has a launch date.On June 20th, CureWise officially launched, and for every cancer patient who walks into an oncologist's office with ten minutes and no idea what to ...
Developing Story: Beyond Camizestrant — The Evolving Landscape of ER+/HER2- MBC with Dr. Sarah Premji
The field of hormone receptor-positive, HER2-negative metastatic breast cancer is moving faster than ever, and in this episode, we go beyond SERENA-6 to map the full picture of what's changing.Joining hosts Victoria Goldberg and Abigail ...
Symptoms Spotlight: Neutropenia with Abigail Johnston and Melanie Sisk
In this episode of the Symptom Spotlight Series, hosts Abigail Johnston and Melanie Sisk are joined by Dr. Jill Tirabassi, this podcast's team member, to break down neutropenia. It is one of the most common and important side effects of cancer ...
Developing Story: The Camizestrant Vote, Doctors Weigh In with Dr. Sarah Sammons & Dr. Neil Vasan
Two weeks ago, we broke down the ODAC vote on camizestrant and SERENA-6 with seven patient advocates. This week, we go deeper — bringing in the clinical and regulatory perspectives from two of the most qualified voices in the field.We're...
Symptoms Spotlight: Melanie's Updates on Sleep Apnea and Constipation
After recording our earlier Symptoms Spotlight episodes on sleep and constipation, Melanie Sisk comes back with real-life updates that prove these topics hit closer to home than she expected. First, Melanie shares her surprising new diagnosis o...
Developing Story: The Camizestrant Vote — When Your Blood Test Knows Before Your Scan Does
The ODAC Vote on Camizestrant & SERENA-6: A Patient Advocate Panel Weighs InWhen the FDA's Oncologic Drugs Advisory Committee voted 6-3 against recommending approval of camizestrant in the SERENA-6 trial setting, the MBC commu...
Front Row Seat: Dr. Fatima Cardoso on Aiming Higher - Hope and the Road to a Cure
In this episode of Life from Stage IV, host Victoria Goldberg sits down with Dr. Fátima Cardoso, Breast oncologist and president of the ABC Global Alliance, to unpack a landmark decade of progress — and confront what still needs to cha...
Front Row Seat: Can We Talk about the Cure? A Conversation with Dr. Eric Winer
For a long time, the word "cure" and "metastatic breast cancer" didn't belong in the same sentence. That's changing — and nobody is better positioned to explain why than today's guest.Dr. Eric Winer is one of the world's leading breast c...
Thriving Together 2026: LBBC's MBC Conference Through Our Eyes
Every year, Living Beyond Breast Cancer (LBBC) brings together hundreds of people living with metastatic breast cancer for one of the most anticipated events in the MBC community, the Thriving Together MBC Conference. This year marked a milesto...
Symptoms Spotlight: Hair Loss with Abigail Johnston and Melanie Sisk
Hair loss is one of the most emotionally complex side effects of cancer treatment — and in this episode of Symptom Spotlights, Abigail Johnston and Melanie Sisk are joined by Lisa Backus and Jill Tirabassi for an honest, practical conversation ...
Front Row Seat: The Enigma of the Blood-Brain Barrier & More with Dr. Nancy Lin
What happens when breast cancer spreads to the brain — and what can actually be done about it? In this episode, host Victoria Goldberg sits down with Dr. Nancy Lin, medical oncologist at Dana-Farber Cancer Institute and one of the country's lea...
