The Chain: Protein Engineering Podcast

Episode: 47 - Bonus Episode with PEGS Young Scientist Keynote Dr. Andrew Anzalone on Engineering Prime Editor Proteins for Therapeutic Applications

Cambridge Healthtech Institute Season 3 Episode 47

Dr. Andrew Anzalone, head of the Prime Editing Platform and scientific co-founder at Prime Medicine, is the winner of the PEGS Boston 2023 Young Scientist Keynote. He was invited to sit down with Brandon DeKosky, assistant professor of chemical engineering at MIT, to discuss prime editing and its precision in treating inherited genetic mutations. Anzalone outlines the next generation tool’s advantages over traditional CRISPR methods and the mechanism creating fewer gene editing errors. He also discusses his clinical training and background, the ongoing projects at Prime Medicine in engineering proteins for cell-based therapeutics, and his thoughts on the current challenges and future developments in gene editing and precision medicine. 

Links from this episode:  
Prime Medicine 
PEGS Boston Conference & Expo