Curcumin vs. Turmeric: The Truth About Absorption, Research & Real Results

Why has curcumin been studied in over 22,000 scientific papers but so many people see little to no results when taking it? #CurcuminBenefits #TurmericVsCurcumin #AntiInflammation #BrainHealth #NaturalHealthPodcast

In this episode of Ultra Life Today, Adam Payne (CEO of Ultra Botanica) and Josh Bellieu break down the science of curcumin vs. turmeric, bioavailability breakthroughs, and common myths about black pepper (piperine) and absorption.

Learn about the "Curcumin Buzz", why most supplements fail, and what cutting-edge technology is changing the game for inflammation, brain health, and longevity.

If you’ve ever wondered whether curcumin can really help with Alzheimer’s, cancer, diabetes, and healthy aging, this episode will surprise you.

📌 What You’ll Learn:
* ✅ Curcumin vs. Turmeric – What’s REALLY in your supplements
* ✅ The shocking truth about black pepper (piperine) and drug interactions
* ✅ Why curcumin research exploded in the last 20 years
* ✅ What causes the "Curcumin Buzz" and how bioavailable forms change results
* ✅ How Ultra Botanica’s technology compares to top brands like BCM-95 and Theracurmin

Listen here or watch to the full episode on YouTube: https://youtu.be/LUdfe79jjTM

Visit UltraBotanica.com to learn more about us and how you can get a free sample of our products.

Transcript

0:00:00 - (Adam Payne): We know that curcumin was essentially was discovered because there were certain populations on the earth where the incidence of Alzheimer's, cancer and later they learned diabetes just was less. And it had nothing to do with the genomic, it had nothing to do with the DNA of the population. It had nothing to do with the geography of the population or the environment, which is those are, are two very tied close together.

0:00:45 - (Adam Payne): What they learned was that it was something in the daily diet that was contributing to lower Alzheimer's, lower cancer rates and ultimately longevity. People living past past 100.

0:01:13 - (Josh Bellieu): Hey everyone. Welcome to I guess what I'm going to call the Fireside Chat episode of Ultral Life Today. I am one of your hosts, Josh Belleew.

0:01:23 - (Adam Payne): Hi, I'm Adam Payne.

0:01:25 - (Josh Bellieu): Adam is the CEO of Ultra Botanica, lead inventor of this incredible technology that we call liquid protein scaffolding. You know, when I said the Fireside Chat atam, I thought about it and I thought, you know, people are not that into presidents these days. That's probably not like, that's probably not elevating our status in the world. Right. Or maybe we can reinvent the Fireside Chat and bring back some life into that.

0:01:49 - (Adam Payne): I guess we're not really near a fire, but we are near some city. Sound baffling.

0:01:53 - (Josh Bellieu): This is going to be a fun episode for both you and I. Adam, I've been on an eight year interesting roller coaster ride with you on a subject called curcumin. A lot of people call it turmeric. That's actually a mistake. Curcumin and turmeric are not the same thing. Although turmeric as we know by weight atam, I believe 3.14% of turmeric by weight is actually curcumin. And curcumin is where the magic, the actives and the most studied because, right. We're looking at 22,400 articles on Pubmed about curcumin. But if you type turmeric and curcumin in, you get about 25,600. So obviously curcumin has been the hot topic on PubMed.

0:02:36 - (Adam Payne): Oh, it's totally been the hot top.

0:02:38 - (Josh Bellieu): Blows aloe vera out of the water. It's. I mean vitamin C has about three times as much now that's amazing that it's actually a third of vitamin C in the ranking now.

0:02:49 - (Adam Payne): It is actually amazing.

0:02:50 - (Josh Bellieu): That's astonishing.

0:02:51 - (Adam Payne): You know, and there's so much. It's one way to measure kind of the pressure or the interest on different substances is to dive into PubMed yeah.

0:03:04 - (Josh Bellieu): Pubmed.gov for people that are brave enough out there to read abstracts and to.

0:03:10 - (Adam Payne): Actually understand how much research has been done on these different substances to make them, it shows how much peer research has been put into it. One research paper is truly something that you just, you can't understand because it's.

0:03:30 - (Josh Bellieu): Well, the difficulty of the process going through the peer reviewed and then getting it into publication. It's a big deal.

0:03:37 - (Adam Payne): It's a huge deal. I mean, it's a research paper is not just something that just pops out of nowhere. There has to be typically over a year of research goes into creating all of the data that goes into a research paper. And then not only that, but then they have to tie it into all of the other published research that'out there on a particular subject. It has to be unique, so it cant be something that somebody else has already done.

0:04:04 - (Adam Payne): And then they have to validate it in this process called peer review. So they submit the paper to a journal and then the journal doesn't just say, oh wow, we got a new paper, let's just publish it. They actually submit it to an editorial board and they have scientists that are experts in their field review the paper for its academic quality only. And then they'll give them feedback, they'll push. Most 99.99% of the time an academic paper gets pushed back and they say, well, here's a hole, here's a hole, here's a hole. Go back and do more research.

0:04:45 - (Josh Bellieu): So with me and my conspiratorial mind, I look at all of the research done on curcumin and I think to myself, because we know how much of this stuff is funded by the pharmaceutical industry. I look at that and I think, man, they have been trying so hard to figure out a way to make an amazing set of drugs out of curcumin. I have to believe that because they'so that's totally true. Yes. So much of it.

0:05:11 - (Adam Payne): And not only that, but they make not only the amount of research that they do about this stuff, Josh, it's the level of scientific research that goes into each paper is astonishing. Yeah, so mean. We've done poster presentations, right. At different scientific conferences. And a poster presentation is typically it's the preliminary research that we'go into maybe contributing to a paper.

0:05:38 - (Josh Bellieu): And how many collective hours of research just off the top of your head went into R1 real poster that we presented recently at the Society of Integrative Oncology.

0:05:48 - (Adam Payne): Hundreds of hours. Ye. Hundreds of hours. So, so let's Just put it into context here. There. There's 26,000 published papers about turmeric and curcumin. Just. Just on curcumin. There's 22,000 published research articles about curcumin. The amount of research has been done.

0:06:09 - (Josh Bellieu): In curcumin and over such a short period of time, it's basically about a dozen years. I was looking at the spike in.

0:06:16 - (Adam Payne): The last 20 years.

0:06:16 - (Josh Bellieu): It's just crazy.

0:06:17 - (Adam Payne): It's 20 years. It's truly just crazy how much research has been done in that.

0:06:23 - (Josh Bellieu): So, you know, I was playing. So let's. Let's go back to Curcumin 101 and Basics because this is very important. I still meet people out there, Adam, that every day say I love turmeric and I put it in my smoothie and I take this big scoop of powder and I put it in things and stuff like that. And yet I still run into people at them. And you know how many stores I've been in, how many people I talk to that are patients of conventional doctors out there that don't even know or have not even heard of curcumin. So let's rewind the tape a little bit.

0:07:01 - (Josh Bellieu): Turmeric is a root or a rhizome.

0:07:04 - (Adam Payne): Right.

0:07:05 - (Josh Bellieu): I believe 80% of it is grown in India. But you've got Pakistan, Malaysia, Sri Lanka, Central America, you've got Vietnam, you've got Hawai. These other place.

0:07:17 - (Adam Payne): Haai.

0:07:17 - (Josh Bellieu): All these other places that kind of make up that other 20% of it's grown, but most just turmeric root.

0:07:23 - (Adam Payne): 99% of turmeric is used in food. It's not used in to make any kind of nutritional supplements or any medicinal products.

0:07:30 - (Josh Bellieu): Yeah. Are my favorite mustard Frenchist mustard out there. It uses lots of turmeric to make thatric beautiful bright yellow.

0:07:37 - (Adam Payne): That color. And actuallyfdc number three is turmeric. It's curcumin.

0:07:44 - (Josh Bellieu): So it's not. It's actually so. Well, now that's nice to know that it may not be a synthesized artificial.

0:07:51 - (Adam Payne): Yeah.

0:07:51 - (Josh Bellieu): Color.

0:07:52 - (Adam Payne): The color. It's one of the only natural colors out there.

0:07:55 - (Josh Bellieu): Wow. See, I knew that I was going to learn something today from Adam. I had no idea it was going to relate to mustard though. Must and artificial color. So that's fun. So let's do a little bit more here and take a deep dive at. And we talk about the fact that roughly 3% of turmeric is curcuminoids and there's three different ones. What are the three different curcuminoids.

0:08:17 - (Adam Payne): Oh, it's A demothhoxy curcumin, B demh, bis dem, myhoxy curcumin and curcumin.

0:08:24 - (Josh Bellieu): Ok, okay. And you've got a little history before and talked about these pan population studies that were done decades ago that where they look at basically cultures around the world and they try to determine why there is less incidence of disease and specific populations. And then most often again, obviously, other than unusual environmental factors that might affect some of those areas, doesn't it oftentimes just come back down to what are they eating?

0:08:53 - (Adam Payne): Yes. In fact, you're bringing up a great question and a point. So we know that curcumin essentially was discovered because there were certain populations on the earth where the incidence of Alzheimer's, cancer and later they learned diabetes was just, was less. And it had nothing to do with the genomic part, it had nothing to do with the DNA of the population. It had nothing to do with the geography of the population or the environment, which is those are two, are two very tied close together.

0:09:44 - (Adam Payne): What they learned was that it was something in the daily diet that was contributing to lower Alzheimer's, lower cancer rates and ultimately longevity. People living past 100.

0:10:02 - (Josh Bellieu): Well, and let's define longevity in a culture like India in a different way. It's not just living longer, it's living better longer. Because if you've got a lower incidence of these major diseases, then the quality of life is so much improved as well.

0:10:19 - (Adam Payne): Yeah, I mean people are happier, they're living better, longer lives. And by and large they're thriving more. I mean just lower cancer, lower Alzheimer's, lower diabetes, living longer lives. So when they cut all the noise out of the equation, the one thing that rose to the surface was the presence of turmeric in the daily diet. And then that started all of the research on what's in turmeric.

0:10:46 - (Josh Bellieu): Right. What is that active? What is there a magic bullet in turmeric? And I have to interject one thing here, Adam. I'm a huge believer that when God puts something together naturally, there's so many beautiful cofactors, there's so many different phytochemicals and things like that and enzymes naturally present that you would find in turmeric. And yet when they isolated curcumin, they really did find that it was the magic, it was what was making things happen.

0:11:16 - (Josh Bellieu): And so I have really gotten fascinated with curcumin as an isolated ingredient and curcum humanoids and what they do. And I dare People to do this, go out to pubmed.govpube.gov, type curcumin and then type any organ in the body, type any disease and I dare you to not find some study that has been published on almost every disease or every organ system as it relates to curcumin. And you'd like to think Adam, oh well we're going to find a bunch of negative press. Guess what?

0:11:54 - (Josh Bellieu): You don't, you don't, you just don't find them going oh my gosh. Other than the blood thinning effects, it just seems to be wide open as a generally accepted beneficial plant bioactive for the body. But it is, we do have struggles though and here's what I found. So I got on PubMed this morning and spent some time there and you know it was so interesting Adam and every incredible headline that I found for research article after research article after research article it always said however there is this limiting factor about curcumin due to its very poor absorption and lack of bioavailability.

0:12:36 - (Josh Bellieu): So there needs to be further exploration on everything from nanoparticle to unique kinds of combining it with fats and all kinds of different things that they'tried that you do find on PubMed. So it is still one of those things where it's like there's a promise of curcumin. That is amazing. But what did you and I learn as we began to talk to people eight years ago that were doctors, that were nutritionists, that were compounding pharmacists who were selling curcumin? What did we find out when we asked them about results?

0:13:09 - (Adam Payne): Ho hum, ho hum.

0:13:11 - (Josh Bellieu): It was like infrequent if it worked and many times very delayed results from the use of it. 30 days, 60 days, 90 days.

0:13:20 - (Adam Payne): Oh it was typically the results that typically we would hear from people was there was a loading time of at least two months for most people before they would start to be able to report on any kind of clinical results. And we see that the BCM 95 studies.

0:13:38 - (Josh Bellieu): Ye yeah, we want to let you know we have, we're huge fans of people like Terry Lemernd of Urop pharma. Terry naturally he's done so many breakthrough things for the industry of supplements introducing various things, making things like glucoseamine and and popular MSM independent health food store. People love this man. So we have nothing but good to say. So there are some really elegant technologies that people have experimented with. Right AdamH absolly out there and his would be one the BCM 95, it hit the shelf. It kind of took over in the curcumin space.

0:14:11 - (Josh Bellieu): A very expensive product which has kind of come down in price over the years a little bit.

0:14:15 - (Adam Payne): Has it?

0:14:15 - (Josh Bellieu): Oh yeah, it has. Well let me say this, it's come down a lot in price. It's still the most expensive I'm aware of on the health food store shelf.

0:14:24 - (Adam Payne): You know, I think it's only selling because it has that on'm the super expensive child on the block kind of aura too.

0:14:31 - (Josh Bellieu): It's got a lot of mystique and I do run into people that it does work fair. But it historically though, again it's a.

0:14:37 - (Adam Payne): Period of time they've done a lot, you know, they've spent a lot their formulation work of research too. Right. You know the original BCM95 technology which most of their product is based upon, they've actually expanded into other technologies over time. It's a ho hum technology. It improves the absorption of the curcuminoids by about a factor of twok. If you dig down in literature, instead of having to take 8 grams of curcumin in order to get any kind.

0:15:10 - (Josh Bellieu): Of that in perspective, that would be 16500 milligram capsules.

0:15:15 - (Adam Payne): Right.

0:15:16 - (Josh Bellieu): Who's going to make a meeting?

0:15:17 - (Adam Payne): Nody's going to do that?

0:15:18 - (Josh Bellieu): Capsules.

0:15:19 - (Adam Payne): So you have to take only eight capsules in order to get maybe to experience a result. That's not saying it, I'm not saying it's not effective. It just it takes a long time for you to accumulate enough of the curcuminoids in your body for it to have an accumulating effect. And that's assuming that you're doing it religiously, taking it every day because this stuff clears out of the body pretty quick.

0:15:47 - (Josh Bellieu): Okay. With a couple of minutes left till our break, we did some comparison studies initially with an off the shelf brand that you and I admit and most doctors we even know say it's the best one at the shelf. And that's the Thera Kerman technology out of Japan, right?

0:16:03 - (Adam Payne): Yep. I think it's a great technology.

0:16:05 - (Josh Bellieu): And again it's one that you know, our friend Joe Tippens, he used to and used to really recommend that. So on a capsule per capsule basis because we, because it is an elegant technology. But on a capsule per capsule basis, what did you find in your mirring studies? Mirring, fancy word for mouse. Studies. Right, or studies. What did we find on a capsule per capsule basis with just our original product with the orange lid ultraar?

0:16:31 - (Adam Payne): Oh, it's boy.

0:16:33 - (Josh Bellieu): It's.

0:16:33 - (Adam Payne): It's six to one. Right, Right.

0:16:35 - (Josh Bellieu): So one capsule of original ultrar is the equivalent of a blood level of a th ken product of six of those.

0:16:43 - (Adam Payne): Six of those. Right. On an equivalent basis. Now, now you have to be fair to the Theraurbin technology. One capsule of Theocurbin is about 30mg b of curcumin.

0:16:58 - (Josh Bellieu): In their formulation they have made into a bio activive compound.

0:17:03 - (Adam Payne): Yes, they've made it into a product that actually gets into the body. It's 30 milligrams of nano sized curcumin particles that have been coated in this gum gadi which allows them to be dispersed. They don't aggregate. It's an elegant technology. So that's the equivalent of about two capsules of our original formula. Two capsules of our original formula will provide 30 milligrams of bioactive bioavailable curcumin.

0:17:36 - (Adam Payne): And so it's five to one of one to the other. So that would be, you know, one capsule of the Theocurbn, about two and a half capsules of our original formula. Theraacirmman is a great technology. You can get results with it. The problem is it causes a lot of gastric upset in people.

0:17:55 - (Josh Bellieu): Yeah. We're going into a break right now. This is Ultra Life Today. I'm Josh Bel I'm hanging out with Adam paying the CEO of Ultra Botanica. We're talking all things human today. S it's an inexhaustible subject but we're going to take a hit on a bunch of other interesting topics.

0:18:10 - (Adam Payne): I don't want to come back to Therakeurman in just a second because we compare it to our pro capsule right after the break. We'll talk about that.

0:18:16 - (Josh Bellieu): We'll do that. We'll be right back.

0:18:21 - (Adam Payne): Our mission is to take nature's most beloved botanicals and enhance them with our liquid protein scaffolds technology. This helps it reach your cells faster and better with exponentially enhanced bioavailability. You'll feel better every day. Ultra Boica the feel good curcumin.

0:18:52 - (Josh Bellieu): Welcome back to Ultra Life Today Part 2 with Adam Payne and Josh Bell. You we're talking all things curcumin, the evolution of curcumin, the discovery of curcumin as it relates to the medical research world. We've got so much more ground to cover. Adam, we were just coming out of the last segment.

0:19:10 - (Adam Payne): I thought we got everything. Have we done it?

0:19:12 - (Josh Bellieu): Thera? Oh, you've Got to be kidding me, right? We could go all day. So we were talking about therarma technology and of course we had an original product that when I met you eight years ago, there was just one product. But you already had things in the innovation pipeline because you had been experimenting with liquid protein scaffold technology with a variety of different types of proteins as well as amino acids. And we did come up the very next product we had that was the major curcumin hitter was for the professionals out there.

0:19:44 - (Josh Bellieu): Credential health professional.

0:19:45 - (Adam Payne): It's our ultrac cur pro ul pro. Right. And so that one capsule of Ultracur Pro provides 60 milligrams of absorbable curcumin.

0:19:53 - (Josh Bellieu): It'on a capsule per capsule basis with our original orangein four times more. Yeah, it's one equals four.

0:19:59 - (Adam Payne): Right. And so just comparing that to theacurbin.

0:20:02 - (Josh Bellieu): Smaller capsule too, easier compliance.

0:20:04 - (Adam Payne): You'd have to do 10 Thera Kerman capsules to get the equivalent of one professional capsule.

0:20:11 - (Josh Bellieu): Yeah. And because we know there's a lot of individuals out there that know of us because we do some products that facilitate supporting healthy cells, differentiation, proliferation ve are for individuals that are dealing with active cancers. When we're talking about the pro product, please don't go out and try to get the pro product because the n acetyl cysteine scaffold in that product is has an unhealthy relationship with with reactive.

0:20:40 - (Adam Payne): Oge with most cancers. Right.

0:20:42 - (Josh Bellieu): So ye. So we have other products that you can look on our website about that. But again, we're not doctors. We're not prescribing. We're not telling you to do something. We're simply talking about curcumin today. And we're talking about all this incredible information you find on med as well as what Adam and I have experienced for literally eight and a half years now with thousands of people and hundreds of doctors worldwide.

0:21:07 - (Adam Payne): We got to go back to the kind of the foundation here. We do the curcumin buzz.

0:21:12 - (Josh Bellieu): Well, okay, come on.

0:21:15 - (Adam Payne): We have to talk about the curcumin book.

0:21:17 - (Josh Bellieu): Okay, so Adam and and friends are sitting around the table. One guy is a guy named Beg Currian. He's a PhD researcher at Oklahoma Memorial Medical Research Foundation. You've got Dr. Hal Schofield is kind.

0:21:30 - (Adam Payne): Of on the side.

0:21:31 - (Josh Bellieu): And Adam says something to BG that literally, like probably made his hair stand on in it did BG goes. We've got this liquefied version of curcumin and it's in a Molecular form atom now. And we just know that in this molecular form it's going to get in the bloodstream. And Adam's like great, do you have jars of it? Let's take shots of it.

0:21:50 - (Adam Payne): O no, no. Even worse than that. I'd said BG Y we sat, we, we, we took some of what you made and we took shots of it yesterday.

0:21:59 - (Josh Bellieu): And he thought you were going to die.

0:22:00 - (Adam Payne): He was like, you can't do thatn have't 50 studies we haven't studied the safety of this formula in humans. And I'm like, I was like. And he was all serious. Of course he was know because in the medical and the research world you're never going to test a substance that's been in research in the research labs on humans until you've done animal studies and toxicity studies and all this work. But you know what?

0:22:26 - (Adam Payne): Curcumin is one of the safest substances ever studied on the planet. They've tried to study a toxic dose of curcumin. They've tried by overeeding turmeric and curcumin to animals and they have never found a toxic dose of curcumin. So when BG was getting all higher than thou on me while I was telling him that we took his liquid curcumin this was like the preecessor predecessor of the Ultra LP's technology.

0:23:03 - (Adam Payne): I said BG, it's safe. There's never been a known toxicity. And he was like yeah, yeah, yeah, I guess you're right, I guess you're right. But then I said bg it's astonishing. We all got something called, we call it the curcumin buzz and there was something about it. And most people when they first try either the original product, like two capsules.

0:23:24 - (Josh Bellieu): Of the original, especially the original because of how quickly it is fully absorbed.

0:23:28 - (Adam Payne): Into the bloodstam especially and an empty stomach, you'll get this in within five minutes. You'll get this kind of like buzz going on.

0:23:37 - (Josh Bellieu): Let'just talk about this kind of well being kind of enhanced cognition kind of thing.

0:23:42 - (Adam Payne): Yeah, it's not bad. It's not like that's not like an alcohol buzz or buz. Yeah, it's not a caffeinated buzz but it's kind of like this light headed kind of not negative, not too positive but we all felt it. We taken the shots of solubleized curcumin and each of us around the table were like are you feeling that? So I knew two things that were happening here Josh. One, it was getting into our bodies.

0:24:07 - (Josh Bellieu): Bbb it's not. The Better Business Bureau is right.

0:24:10 - (Adam Payne): It's the blood brain barrier. And the fact that we were feeling it in that way meant that those curcumin molecules were getting past the blood brain barrier and getting into our ce.

0:24:21 - (Josh Bellieu): By the way, we've done a permeability study now to prove that is actually true about ultrac cur.

0:24:27 - (Adam Payne): It was done at the University of Texas. We did a permeability study on the gut. We did some. Actually, it wasn't us, it was another research group and did a permeability study on the brain and it's getting it. And that was done on our LPs product, our curcumin bound to whey protein. So not only do we know that it's getting into the body, but it's actually getting into the central nervous system here.

0:24:49 - (Josh Bellieu): So, Adam, I want to. I want to say something because one of the things I began to find is I began to meet individuals out there that were taking curcumin. And this is going to move us kind of back into the. Into the last thing I think you wanted to say about Thera Garman. And that is I began to hear individuals say, you know, I was taking curcumin, I was taking large amounts of it and. Or not even large amounts of it and saying they were having gastric upset, they lot stomach issues lot.

0:25:19 - (Josh Bellieu): That is one of the things that I'm so proud to be able to say because I have people all the time. We've got new pharmacies and new doctors and health professionals onboarding all the time for their patient populations. And they're like, what are the adverse events associated with ultracur? I need to know. And I said, well, number one, and this is important, we put it right on the label. Curcumin is noted in the medical literature to affect the fxa. No to the thrombin pathway.

0:25:45 - (Adam Payne): Oh, very mean.

0:25:46 - (Josh Bellieu): Meaning it will thin the blood.

0:25:48 - (Adam Payne): It does th blood.

0:25:50 - (Josh Bellieu): But then when you guys came out with what I call like this literally light years'rocket fuel type version of curcumin that's hitting the bloodstream at elevated levels, it's like, we do really want to monitor that. So we do put a warning on the label related to anyone taking prescription blood thinners, please consult Dr. First. However, what I thought was really cool, Adam, is, you know, in eight and a half years, our dear friend Mary Jane Fry, she.

0:26:17 - (Josh Bellieu): She called me a couple of different times over the years and said, I do have a client that has ended up with some stomach issues. And she says and I'm not sure whether it's because they're high toxic anyway, you know, detoxing them from other different things. But I have found Adam almost a zero incidence of herzheimer reactions with people taking ultracr which has been so cool to me because that is one of the things that does scare a lot of people off from standard curcumin. It doesn't absorb, it sits in the gut. And what do we have happen?

0:26:50 - (Josh Bellieu): People struggle.

0:26:53 - (Adam Payne): It's astonishing how many problems come because people don't understand kind of the impact of the nutritional supplements and the pharmaceuticals that people are taking on their human condition. You know, I think we're the only curcumin company that'been reporting on this blood thinning aspect to it.

0:27:11 - (Josh Bellieu): I've never seen it on another bottle.

0:27:13 - (Adam Payne): Al well and you know why? Its because we'getting into the body and most of the others arent. And we see this effect especially with the pro product. The big reason why we only sell the professional grade product only through clinical practices is because this can be an.

0:27:30 - (Josh Bellieu): Issue we want a doctor consultation involved in.

0:27:32 - (Adam Payne): Oh, you take more than three of these important in a short period of time, you're going to bruise.

0:27:37 - (Josh Bellieu): Yeah, it is indeed possible. You know, you, me, our friend Kyle Drew of super health fame. He and I experiment with large amounts at different times of different products of ours. And so we have gotten to the point where we did notice we were bruising easily. And the big remedy that back off, back off.

0:27:57 - (Adam Payne): You have to back off, back off of what you're using very quickly reverses. So don't overdo it.

0:28:02 - (Josh Bellieu): So let's do something here with let's.

0:28:04 - (Adam Payne): And there's no need to go above and beyond the levels that people that where people are bruising. Well really.

0:28:10 - (Josh Bellieu): And I tell people, Adam, we oftentimes tell people on the front end especially as it relates to our products maybe like the original Ultracr or the advanced. You can dose load a bit that first 15 to 30 days if you're really struggling with discomfort in your body, mobility issues. But then I tell people once you have achieved the result you want, play with the amount you're taking to see what helps you maintain those results. Absoutely because I have many people that take less after that first month, you know and maintain the results.

0:28:40 - (Josh Bellieu): Okay, we've got about four minutes left and this is a really cool thing for us to do before we start hitting headlines of really interesting research studies. Let's talk a little bit about bioerine piperine, black pepper extract, all the same thing. One thing you do find among people that know turmeric and no curcumin, they go, my turmeric can curcumin, by golly, by Yemeni. It has black pepper extract in it or piperine or berine.

0:29:10 - (Josh Bellieu): Why did you and I key in on that in the beginning, Adam? And then you did it took a deep dive and you go, wa a minute, wait a minute. This is inappropriate to put in a supplement, especially with individuals that historically the population taking the age demographic, taking curcumin and turmeric, they're frequently fiftyus, fifty plus. And they're on what, A lot of medications.

0:29:34 - (Adam Payne): A lot of medications.

0:29:35 - (Josh Bellieu): Let's talk about this a minute.

0:29:36 - (Adam Payne): Okay, so most people have a fable going on in their head about what pipriid, this black pepper extract is doing. Most people think that black pepper extract is improving the absorption of curcumin molecules.

0:29:56 - (Josh Bellieu): Into the it, its turning curcumin into an intravenous injection.

0:29:59 - (Adam Payne): And they have all of these great theories. So I even have one of my favorite friends, Boris Gorrenstein, who is a naturopath. He still believes this.

0:30:09 - (Josh Bellieu): Super sharp guy.

0:30:09 - (Adam Payne): Super sharp guy. He thinks, okay. His fable goes as follows. Well, black pepper is an irritant and it's inflaming the tissues a little bit in the gut. Gu. And that's improving the permeability of the gut. And that's why curcumin is absorbing more. Well, if it was, if black pepper was irritating the gut, that would actually decrease the absorption of nutrients. That's what Crohn's disease, our celiac disease, is doing'causing microf inflammation in the villi in the small intestines and that decreases absorption. So guess what, folks?

0:30:47 - (Adam Payne): Black pepper does not improve the absorption of anything into the body. What it is doing is it is inhibiting a key enzyme that is responsible for the breakdown of compounds like curcumin through a process called glucaronidation. And there's an enzyme in the liver called glucuronidase that is responsible for cutting curcumin molecules, cleaving them into two parts. And it also is responsible for the cleavage of about 40 different pharmaceutical products.

0:31:25 - (Josh Bellieu): Well, now products are classes.

0:31:27 - (Adam Payne): Classes of products.

0:31:28 - (Josh Bellieu): Now we get into hundreds, thousands of drugs.

0:31:31 - (Adam Payne): Classes. Yeah, yeah, yeah, yeah. And, and, and it's. All that piperine is doing is inhibiting that enzyme. So it's not improving the absorption of curcumin into the body. It is slowing down the rate your liver is Eliminating curcumin from your body.

0:31:50 - (Josh Bellieu): Being able to clear it, a process.

0:31:52 - (Adam Payne): So what it's doing artificially is it's increasing the amount of curcumin that you have in your circulation by decreasing the amount that gets chewed up. And so, yeah, it's elegant. If it didn't affect all of these other pharmaceutical classes of drugs, I would say it would be really cool. But the fact remains piperine can affect pharmaceutical products. And so if you're on any pharmaceutical drugs, please stay away from piperin unless you clear it with a good clinical nutritionist.

0:32:28 - (Josh Bellieu): Ye. And it comes natur, pepperin, byariine, black pepper extract. It'll even say like something niger on it, you know, which is just the pipper nitro. Yeah, black pepper. And we have a lot of. And I will say this, we do. We have a lot of close friends of mine, Adam, that are naturopathic or they'functional integrative people. And they say, hey, we've seen black pepper as a culprit that simply does irritate the stomach lining. And it's negative for our patients to have an irritated stomach.

0:32:59 - (Adam Payne): Gratefully to God and the universe, we don't need black pepper extract for people to experience the benefits of curcumin. We have so much curcumin is absorbed through our LPs technology, and it does.

0:33:12 - (Josh Bellieu): It so quickly that it doesn't have a chance to sit in the gut and create gastric upset.

0:33:17 - (Adam Payne): It doesn't create gastric upset. We get in so much of it that we get a bolus of it all over the body. And we actually. People experience a difference. 70% of people that take our product. Josh, just the original. Experience a dramatic benefit within a week, 55% of people within 24 hours. And a whopping 35% of people that take Ultraur, the original formula, experience a dramatic benefit within two hours.

0:33:44 - (Josh Bellieu): Yeah. And that survey, by the way, was done with original ultraur and only two capsules a day. This is Ultra Life today. Adam Payne, CEO of Ultra Botanic, elite inventor on the LP's technology We've been discussing. I'm Josh Belw.

0:33:58 - (Adam Payne): Please come back.